Michael D. Rosenblum

Publications

• Transcriptomic Profiling of Plaque Psoriasis and Cutaneous T-Cell Subsets During Treatment with Secukinumab
  JID Innovations : Skin Science from Molecules to Population Health. May, 2022  |   Pubmed ID: 35757784
• Identifying and Antagonizing the Interactions Between Layilin and Glycosylated Collagens
  Cell Chemical Biology. Apr, 2022  |   Pubmed ID: 35104453
• Regulatory T Cells and Inflammatory Mediators in Autoimmune Disease
  The Journal of Investigative Dermatology. 03, 2022  |   Pubmed ID: 34284898
• T-Cell Adhesion in Healthy and Inflamed Skin
  JID Innovations : Skin Science from Molecules to Population Health. Jun, 2021  |   Pubmed ID: 35024681
• Early-life Inflammation Primes a T Helper 2 Cell-fibroblast Niche in Skin
  Nature. 11, 2021  |   Pubmed ID: 34707292
• Layilin Anchors Regulatory T Cells in Skin
  Journal of Immunology (Baltimore, Md. : 1950). 10, 2021  |   Pubmed ID: 34470859
• Regulatory T Cells Promote Innate Inflammation After Skin Barrier Breach Via TGF-β Activation
  Science Immunology. 08, 2021  |   Pubmed ID: 34452925
• Integrin αvβ8 on T cells Suppresses Anti-tumor Immunity in Multiple Models and is a Promising Target for Tumor Immunotherapy
  Cell Reports. 07, 2021  |   Pubmed ID: 34233193
• TGF-β: Deletion of TGF-β in T Revisited
  Science Immunology. 02, 2021  |   Pubmed ID: 33547050
• Single-cell RNA Sequencing of Psoriatic Skin Identifies Pathogenic Tc17 Cell Subsets and Reveals Distinctions Between CD8 T Cells in Autoimmunity and Cancer
  The Journal of Allergy and Clinical Immunology. 06, 2021  |   Pubmed ID: 33309739
• Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature
  Cell Reports. Medicine. 11, 2020  |   Pubmed ID: 33294857
• Keepin' It Regulatory: Foxp3 Gets a BAFfling SWItch
  Science Immunology. 09, 2020  |   Pubmed ID: 32887845
• Contribution of Plasma Cells and B Cells to Hidradenitis Suppurativa Pathogenesis
  JCI Insight. 10, 2020  |   Pubmed ID: 32853177
• Immunopathogenesis of Hidradenitis Suppurativa and Response to Anti-TNF-α Therapy
  JCI Insight. 10, 2020  |   Pubmed ID: 32841223
• Exhausted T Cell Signature Predicts Immunotherapy Response in ER-positive Breast Cancer
  Nature Communications. 07, 2020  |   Pubmed ID: 32681091
• Layilin Augments Integrin Activation to Promote Antitumor Immunity
  The Journal of Experimental Medicine. 09, 2020  |   Pubmed ID: 32539073
• Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma
  Annals of Surgical Oncology. Oct, 2020  |   Pubmed ID: 32488521
• Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2020  |   Pubmed ID: 32376655
• Regulatory T Cells in Skin Injury: At the Crossroads of Tolerance and Tissue Repair
  Science Immunology. 05, 2020  |   Pubmed ID: 32358172
• Sex Drives T into Fat
  Science Immunology. 04, 2020  |   Pubmed ID: 32245886
• An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease
  Biomaterials. 02, 2020  |   Pubmed ID: 31753473
• Y'all Comeback Now
  Science Immunology. 05, 2019  |   Pubmed ID: 32619187
• Regulatory T Cells Use Arginase 2 to Enhance Their Metabolic Fitness in Tissues
  JCI Insight. 12, 2019  |   Pubmed ID: 31852848
• Regulatory T Cells in Skin Are Uniquely Poised to Suppress Profibrotic Immune Responses
  Science Immunology. 09, 2019  |   Pubmed ID: 31492709
• CD27 Promotes CD4 Effector T Cell Survival in Response to Tissue Self-Antigen
  Journal of Immunology (Baltimore, Md. : 1950). 08, 2019  |   Pubmed ID: 31209102
• Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair
  Immunity. 03, 2019  |   Pubmed ID: 30893588
• Inflammatory T Cells Maintain a Healing Disposition
  Science Immunology. 01, 2019  |   Pubmed ID: 30610014
• The TNFRSF Members CD27 and OX40 Coordinately Limit T17 Differentiation in Regulatory T Cells
  Science Immunology. 12, 2018  |   Pubmed ID: 30578350
• Tissue-specific Contributions of to Atopic Dermatitis and Mast Cell-mediated Histaminergic Itch
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2018  |   Pubmed ID: 30463955
• Colitis Interruptus: LAGing Gut Inflammation
  Science Immunology. 09, 2018  |   Pubmed ID: 30194243
• Alteration of the Cutaneous Microbiome in Psoriasis and Potential Role in Th17 Polarization
  Microbiome. 09, 2018  |   Pubmed ID: 30185226
• A Natural Killer-dendritic Cell Axis Defines Checkpoint Therapy-responsive Tumor Microenvironments
  Nature Medicine. 08, 2018  |   Pubmed ID: 29942093
• Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity
  Cell Reports. 06, 2018  |   Pubmed ID: 29898397
• Fas Ligand Promotes an Inducible TLR-dependent Model of Cutaneous Lupus-like Inflammation
  The Journal of Clinical Investigation. 07, 2018  |   Pubmed ID: 29889098
• Say It Isn't Pso: IL-25 Drives Skin Inflammation
  Science Immunology. 05, 2018  |   Pubmed ID: 29728428
• Skin-Resident T Cells Drive Dermal Dendritic Cell Migration in Response to Tissue Self-Antigen
  Journal of Immunology (Baltimore, Md. : 1950). 05, 2018  |   Pubmed ID: 29563179
• HDAC Inhibition Potentiates Immunotherapy in Triple Negative Breast Cancer
  Oncotarget. Dec, 2017  |   Pubmed ID: 29371976
• Genomic Analysis of Atypical Fibroxanthoma
  PloS One. 2017  |   Pubmed ID: 29141020
• Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators
  ACS Nano. 11, 2017  |   Pubmed ID: 29124929
• Partially Exhausted Tumor-infiltrating Lymphocytes Predict Response to Combination Immunotherapy
  JCI Insight. Jul, 2017  |   Pubmed ID: 28724802
• Regulatory T Cells in Skin
  Immunology. 11, 2017  |   Pubmed ID: 28699278
• Skin-infiltrating, Interleukin-22-producing T Cells Differentiate Pediatric Psoriasis from Adult Psoriasis
  Journal of the American Academy of Dermatology. Sep, 2017  |   Pubmed ID: 28624119
• Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation
  Cell. Jun, 2017  |   Pubmed ID: 28552347
• Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
  Cell Host & Microbe. Apr, 2017  |   Pubmed ID: 28343820
• Tumor Immune Profiling Predicts Response to Anti-PD-1 Therapy in Human Melanoma
  The Journal of Clinical Investigation. 09, 2016  |   Pubmed ID: 27525433
• Plasmacytoid Dendritic Cells (pDCs) and Regulatory T (Treg) Cells May Be the Key to Viral Reactivation in Drug-induced Hypersensitivity Syndrome (DIHS)
  Journal of the American Academy of Dermatology. Jun, 2016  |   Pubmed ID: 27185444
• Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2016  |   Pubmed ID: 26826250
• The Distribution of Cutaneous Metastases Correlates with Local Immunologic Milieu
  Journal of the American Academy of Dermatology. Mar, 2016  |   Pubmed ID: 26778012
• Regulatory T Cell Memory
  Nature Reviews. Immunology. Feb, 2016  |   Pubmed ID: 26688349
• A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes
  Immunity. Nov, 2015  |   Pubmed ID: 26588783
• COPA Mutations Impair ER-Golgi Transport and Cause Hereditary Autoimmune-mediated Lung Disease and Arthritis
  Nature Genetics. Jun, 2015  |   Pubmed ID: 25894502
• Mechanisms of Human Autoimmunity
  The Journal of Clinical Investigation. Jun, 2015  |   Pubmed ID: 25893595
• Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-presenting Cells Critical for T Cell Immunity
  Cancer Cell. Nov, 2014  |   Pubmed ID: 25446897
• Melanoma Immunotherapy
  Cancer Biology & Therapy. Jun, 2014  |   Pubmed ID: 24651672
• A Case of Wong-type Dermatomyositis with Concomitant Anti-MDA5 Features
  Journal of the American Academy of Dermatology. Mar, 2014  |   Pubmed ID: 24528920
• Memory Regulatory T Cells Reside in Human Skin
  The Journal of Clinical Investigation. Mar, 2014  |   Pubmed ID: 24509084
• Cutting Edge: Self-antigen Controls the Balance Between Effector and Regulatory T Cells in Peripheral Tissues
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2014  |   Pubmed ID: 24442443
• An Open-label Study of Anakinra for the Treatment Of moderate to Severe Hidradenitis Suppurativa
  Journal of the American Academy of Dermatology. Feb, 2014  |   Pubmed ID: 24314876
• Cutting Edge: ABIN-1 Protects Against Psoriasis by Restricting MyD88 Signals in Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2013  |   Pubmed ID: 23785118
• Depleting Tumor-specific Tregs at a Single Site Eradicates Disseminated Tumors
  The Journal of Clinical Investigation. Jun, 2013  |   Pubmed ID: 23728179
• Treating Human Autoimmunity: Current Practice and Future Prospects
  Science Translational Medicine. Mar, 2012  |   Pubmed ID: 22422994
• Response to Self Antigen Imprints Regulatory Memory in Tissues
  Nature. Nov, 2011  |   Pubmed ID: 22121024