Michael R. Gold

Publications

• The Rap2c GTPase Facilitates B Cell Receptor-induced Reorientation of the Microtubule-organizing Center
  Small GTPases. Feb, 2018  |   Pubmed ID: 29457987
• Imaging the Interactions Between B Cells and Antigen-Presenting Cells
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 29388105
• The Interaction of Sex, Height, and QRS Duration on the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality: an Individual-patient Data Meta-analysis
  European Journal of Heart Failure. Jan, 2018  |   Pubmed ID: 29314424
• Precision Medicine for Cardiac Resynchronization: Predicting Quality of Life Benefits for Individual Patients-An Analysis From 5 Clinical Trials
  Circulation. Heart Failure. Oct, 2017  |   Pubmed ID: 29038172
• Limitations of Qdot Labelling Compared to Directly-conjugated Probes for Single Particle Tracking of B Cell Receptor Mobility
  Scientific Reports. Sep, 2017  |   Pubmed ID: 28900238
• Predictors of Short-term Clinical Response to Cardiac Resynchronization Therapy
  European Journal of Heart Failure. Aug, 2017  |   Pubmed ID: 28295869
• The Rap1-cofilin-1 Pathway Coordinates Actin Reorganization and MTOC Polarization at the B Cell Immune Synapse
  Journal of Cell Science. 03, 2017  |   Pubmed ID: 28167682
• Applied Stretch Initiates Directional Invasion Through the Action of Rap1 GTPase As a Tension Sensor
  Journal of Cell Science. 01, 2017  |   Pubmed ID: 27199371
• What Goes Up Must Come Down: A Tripartite Dok-3/Grb2/SHIP1 Inhibitory Module Limits BCR Signaling
  European Journal of Immunology. Nov, 2016  |   Pubmed ID: 27813071
• SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling
  Developmental Cell. Apr, 2016  |   Pubmed ID: 27046831
• The Paracaspase MALT1 Cleaves HOIL1 Reducing Linear Ubiquitination by LUBAC to Dampen Lymphocyte NF-κB Signalling
  Nature Communications. Nov, 2015  |   Pubmed ID: 26525107
• Toll-like Receptor Ligands Sensitize B-cell Receptor Signalling by Reducing Actin-dependent Spatial Confinement of the Receptor
  Nature Communications. Feb, 2015  |   Pubmed ID: 25644899
• PI3K Signaling in B Cell and T Cell Biology
  Frontiers in Immunology. 2014  |   Pubmed ID: 25404931
• An Individual Patient Meta-analysis of Five Randomized Trials Assessing the Effects of Cardiac Resynchronization Therapy on Morbidity and Mortality in Patients with Symptomatic Heart Failure
  European Heart Journal. Dec, 2013  |   Pubmed ID: 23900696
• Control of the Hippo Pathway by Set7-dependent Methylation of Yap
  Developmental Cell. Jul, 2013  |   Pubmed ID: 23850191
• The Invasion Inhibitor Sarasinoside A1 Reverses Mesenchymal Tumor Transformation in an E-cadherin-independent Manner
  Molecular Cancer Research : MCR. May, 2013  |   Pubmed ID: 23399642
• Selective Pharmacological Inhibition of Phosphoinositide 3-kinase P110delta Opposes the Progression of Autoimmune Diabetes in Non-obese Diabetic (NOD) Mice
  Autoimmunity. Feb, 2013  |   Pubmed ID: 23039284
• Small Molecule Inhibitors of the Pyk2 and FAK Kinases Modulate Chemoattractant-induced Migration, Adhesion and Akt Activation in Follicular and Marginal Zone B Cells
  Cellular Immunology. Jan-Feb, 2012  |   Pubmed ID: 22507871
• Cofilin-mediated F-actin Severing is Regulated by the Rap GTPase and Controls the Cytoskeletal Dynamics That Drive Lymphocyte Spreading and BCR Microcluster Formation
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2011  |   Pubmed ID: 22068232
• Opposing Roles for CD34 in B16 Melanoma Tumor Growth Alter Early Stage Vasculature and Late Stage Immune Cell Infiltration
  PloS One. Apr, 2011  |   Pubmed ID: 21494591
• TNFR1 Delivers Pro-survival Signals That Are Required for Limiting TNFR2-dependent Activation-induced Cell Death (AICD) in CD8+ T Cells
  European Journal of Immunology. Feb, 2011  |   Pubmed ID: 21268004
• Preventing the Activation or Cycling of the Rap1 GTPase Alters Adhesion and Cytoskeletal Dynamics and Blocks Metastatic Melanoma Cell Extravasation into the Lungs
  Cancer Research. Jun, 2010  |   Pubmed ID: 20484042
• Rap GTPase-mediated Adhesion and Migration: A Target for Limiting the Dissemination of B-cell Lymphomas?
  Cell Adhesion & Migration. Jul-Sep, 2010  |   Pubmed ID: 20212359
• Phosphoinositide 3-kinase P110 Delta Regulates Natural Antibody Production, Marginal Zone and B-1 B Cell Function, and Autoantibody Responses
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2009  |   Pubmed ID: 19843950
• Localized Diacylglycerol-dependent Stimulation of Ras and Rap1 During Phagocytosis
  The Journal of Biological Chemistry. Oct, 2009  |   Pubmed ID: 19700408
• B Cell Receptor-induced Phosphorylation of Pyk2 and Focal Adhesion Kinase Involves Integrins and the Rap GTPases and is Required for B Cell Spreading
  The Journal of Biological Chemistry. Aug, 2009  |   Pubmed ID: 19561089
• Lymphocytes in the Peritoneum Home to the Omentum and Are Activated by Resident Dendritic Cells
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009  |   Pubmed ID: 19553538
• B Cell Development: Important Work for ERK
  Immunity. Apr, 2008  |   Pubmed ID: 18400191
• The Rap GTPases Regulate B Cell Morphology, Immune-synapse Formation, and Signaling by Particulate B Cell Receptor Ligands
  Immunity. Jan, 2008  |   Pubmed ID: 18191594
• Differential Role of Reactive Oxygen Species in the Activation of Mitogen-activated Protein Kinases and Akt by Key Receptors on B-lymphocytes: CD40, the B Cell Antigen Receptor, and CXCR4
  Journal of Cell Communication and Signaling. Jun, 2007  |   Pubmed ID: 18481208
• The Rap GTPases Mediate CXCL13- and Sphingosine1-phosphate-induced Chemotaxis, Adhesion, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes
  European Journal of Immunology. Aug, 2006  |   Pubmed ID: 16821235
• The Rap GTPases Regulate Integrin-mediated Adhesion, Cell Spreading, Actin Polymerization, and Pyk2 Tyrosine Phosphorylation in B Lymphocytes
  The Journal of Biological Chemistry. Mar, 2004  |   Pubmed ID: 14701796
• Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation
  The Journal of Biological Chemistry. Oct, 2003  |   Pubmed ID: 12904304
• Akt is TCL-ish: Implications for B-cell Lymphoma
  Trends in Immunology. Mar, 2003  |   Pubmed ID: 12615201
• The Human Antimicrobial Peptide LL-37 is a Multifunctional Modulator of Innate Immune Responses
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002  |   Pubmed ID: 12244186
• The Rap GTPases Regulate B Cell Migration Toward the Chemokine Stromal Cell-derived Factor-1 (CXCL12): Potential Role for Rap2 in Promoting B Cell Migration
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2002  |   Pubmed ID: 12133960
• To Make Antibodies or Not: Signaling by the B-cell Antigen Receptor
  Trends in Pharmacological Sciences. Jul, 2002  |   Pubmed ID: 12119152
• The B Cell Antigen Receptor Regulates the Transcriptional Activator Beta-catenin Via Protein Kinase C-mediated Inhibition of Glycogen Synthase Kinase-3
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002  |   Pubmed ID: 12097378
• Activation and Phosphatidylinositol 3-kinase-dependent Phosphorylation of Protein Kinase C-epsilon by the B Cell Antigen Receptor
  Immunology Letters. Jul, 2002  |   Pubmed ID: 12036603
• The Direct Recruitment of BLNK to Immunoglobulin Alpha Couples the B-cell Antigen Receptor to Distal Signaling Pathways
  Molecular and Cellular Biology. Apr, 2002  |   Pubmed ID: 11909947
• CD40 Signaling in B Cells Regulates the Expression of the Pim-1 Kinase Via the NF-kappa B Pathway
  Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002  |   Pubmed ID: 11777968
• Interaction of Cationic Peptides with Lipoteichoic Acid and Gram-positive Bacteria
  Infection and Immunity. Dec, 1999  |   Pubmed ID: 10569762
• Dendritic Cell Survival and Maturation Are Regulated by Different Signaling Pathways
  The Journal of Experimental Medicine. Dec, 1998  |   Pubmed ID: 9841930
• Listeria Monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-activated Protein Kinase Pathway
  Infection and Immunity. Mar, 1998  |   Pubmed ID: 9488402