Michael V. Sefton Institute of Biomaterials and Biomedical Engineering / Department of Chemical Engineering and Applied Chemistry University of Toronto Biography Publications Institution JoVE Articles Michael V. Sefton has not added a biography. If you are Michael V. Sefton and would like to personalize this page please email our Author Liaison for assistance. Publications Recovery of Cardiac Function Mediated by MSC and Interleukin-10 Plasmid Functionalised Scaffold Biomaterials. Feb, 2012 | Pubmed ID: 22078809 Bone Marrow-derived Mesenchymal Stromal Cells Enhance Chimeric Vessel Development Driven by Endothelial Cell-coated Microtissues Tissue Engineering. Part A. Feb, 2012 | Pubmed ID: 21861779 Toward an In Vitro Vasculature: Differentiation of Mesenchymal Stromal Cells Within an Endothelial Cell-Seeded Modular Construct in a Microfluidic Flow Chamber Tissue Engineering. Part A. Dec, 2011 | Pubmed ID: 21992078 On the Mechanism of Poly(methacrylic Acid -co- Methyl Methacrylate)-induced Angiogenesis: Gene Expression Analysis of DTHP-1 Cells Biomaterials. Dec, 2011 | Pubmed ID: 21872324 Endothelialized Biomaterials for Tissue Engineering Applications in Vivo Trends in Biotechnology. Aug, 2011 | Pubmed ID: 21549438 Application of an Endothelialized Modular Construct for Islet Transplantation in Syngeneic and Allogeneic Immunosuppressed Rat Models Tissue Engineering. Part A. Aug, 2011 | Pubmed ID: 21449709 Endothelial Cell Behaviour Within a Microfluidic Mimic of the Flow Channels of a Modular Tissue Engineered Construct Biomedical Microdevices. Feb, 2011 | Pubmed ID: 20842530 Chimeric Vessel Tissue Engineering Driven by Endothelialized Modules in Immunosuppressed Sprague-Dawley Rats Tissue Engineering. Part A. Jan, 2011 | Pubmed ID: 20695789 Effectiveness Factor and Diffusion Limitations in Collagen Gel Modules Containing HepG2 Cells Journal of Tissue Engineering and Regenerative Medicine. Feb, 2011 | Pubmed ID: 20653045 A Poloxamine-Polylysine Acrylate Scaffold for Modular Tissue Engineering Journal of Biomaterials Science. Polymer Edition. Dec, 2010 | Pubmed ID: 21144169 Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications Journal of Biomaterials Science. Polymer Edition. Dec, 2010 | Pubmed ID: 21144168 Perfusion and Characterization of an Endothelial Cell-seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber Biomaterials. Nov, 2010 | Pubmed ID: 20678792 A Modular Approach to Cardiac Tissue Engineering Tissue Engineering. Part A. Oct, 2010 | Pubmed ID: 20504074 MMP Levels in the Response to Degradable Implants in the Presence of a Hydroxamate-based Matrix Metalloproteinase Sequestering Biomaterial in Vivo Journal of Biomedical Materials Research. Part A. Jun, 2010 | Pubmed ID: 19911383 Poly(methacrylic Acid-co-methyl Methacrylate) Beads Promote Vascularization and Wound Repair in Diabetic Mice Journal of Biomedical Materials Research. Part A. May, 2010 | Pubmed ID: 19585566 Effect of a Matrix Metalloproteinase Sequestering Biomaterial on Caco-2 Epithelial Cell Barrier Integrity in Vitro Acta Biomaterialia. Jul, 2009 | Pubmed ID: 19307161 Fate of Endothelialized Modular Constructs Implanted in an Omental Pouch in Nude Rats Tissue Engineering. Part A. Oct, 2009 | Pubmed ID: 19265460 The Effect of a Hydroxamic Acid-containing Polymer on Active Matrix Metalloproteinases Biomaterials. Apr, 2009 | Pubmed ID: 19147221 Dual Delivery of Placental Growth Factor and Vascular Endothelial Growth Factor from Poly(hydroxyethyl Methacrylate-co-methyl Methacrylate) Microcapsules Containing Doubly Transfected Luciferase-expressing L929 Cells Tissue Engineering. Part A. Aug, 2009 | Pubmed ID: 19125649 Acceleration of Diabetic Wound Healing by an Angiopoietin Peptide Mimetic Tissue Engineering. Part A. Jun, 2009 | Pubmed ID: 18939935 IL-10 Secretion Increases Signal Persistence of HEMA-MMA-microencapsulated Luciferase-modified CHO Fibroblasts in Mice Tissue Engineering. Part A. Jan, 2009 | Pubmed ID: 18710337 Amidine Surface Modification of Poly(acrylonitrile-co-vinyl Chloride) Reduces Platelet Adhesion Journal of Biomedical Materials Research. Part A. Jun, 2009 | Pubmed ID: 18465816 A Preliminary Study of the Effect of Poly(methacrylic Acid-co-methyl Methacrylate) Beads on Angiogenesis in Rodent Skin Grafts and the Quality of the Panniculus Carnosus Plastic and Reconstructive Surgery. Nov, 2008 | Pubmed ID: 18971719 The Thrombogenicity of Human Umbilical Vein Endothelial Cell Seeded Collagen Modules Biomaterials. Jun, 2008 | Pubmed ID: 18325586 Innate and Adaptive Immune Responses in Tissue Engineering Seminars in Immunology. Apr, 2008 | Pubmed ID: 18221888 Effect of Mouse VEGF164 on the Viability of Hydroxyethyl Methacrylate-methyl Methacrylate-microencapsulated Cells in Vivo: Bioluminescence Imaging Journal of Biomedical Materials Research. Part A. Nov, 2008 | Pubmed ID: 18181105 Lactoyl-poloxamine/collagen Matrix for Cell-containing Tissue Engineering Modules Journal of Biomedical Materials Research. Part A. Aug, 2008 | Pubmed ID: 17969022 Modular Tissue Engineering: Fabrication of a Gelatin-based Construct Journal of Tissue Engineering and Regenerative Medicine. Mar-Apr, 2007 | Pubmed ID: 18038402 A Modular Tissue Engineering Construct Containing Smooth Muscle Cells and Endothelial Cells Annals of Biomedical Engineering. Dec, 2007 | Pubmed ID: 17882548 Design and Fabrication of Sub-mm-sized Modules Containing Encapsulated Cells for Modular Tissue Engineering Tissue Engineering. May, 2007 | Pubmed ID: 17582838 Poly(butyl Methacrylate-co-methacrylic Acid) Tissue Engineering Scaffold with Pro-angiogenic Potential in Vivo Journal of Biomedical Materials Research. Part A. Aug, 2007 | Pubmed ID: 17530634 Vascularization and Improved in Vivo Survival of VEGF-secreting Cells Microencapsulated in HEMA-MMA Tissue Engineering. Sep, 2007 | Pubmed ID: 17523877 Design Criteria for a Modular Tissue-engineered Construct Tissue Engineering. May, 2007 | Pubmed ID: 17439395 The Influence of Biomaterials on Endothelial Cell Thrombogenicity Biomaterials. Jun, 2007 | Pubmed ID: 17316788 Tissue Factor and Thrombomodulin Expression on Endothelial Cell-seeded Collagen Modules for Tissue Engineering Journal of Biomedical Materials Research. Part A. Feb, 2007 | Pubmed ID: 17111414 Advanced Tools for Tissue Engineering: Scaffolds, Bioreactors, and Signaling Tissue Engineering. Dec, 2006 | Pubmed ID: 17518670 Fabrication of Cell-containing Gel Modules to Assemble Modular Tissue-engineered Constructs [corrected] Nature Protocols. 2006 | Pubmed ID: 17406556 Suppressed Splenocyte Proliferation Following a Xenogeneic Skin Graft Due to Implanted Biomaterials Transplantation. Aug, 2006 | Pubmed ID: 16906042 Vascularized Organoid Engineered by Modular Assembly Enables Blood Perfusion Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16864785 Methylation of Poloxamine for Enhanced Cell Adhesion Biomacromolecules. Jan, 2006 | Pubmed ID: 16398533 Surface Study of Collagen/poloxamine Hydrogels by a 'deep Freezing' ToF-SIMS Approach Biomaterials. Apr, 2006 | Pubmed ID: 16332388 Collagen/poloxamine Hydrogels: Cytocompatibility of Embedded HepG2 Cells and Surface-attached Endothelial Cells Tissue Engineering. Nov-Dec, 2005 | Pubmed ID: 16411826 Conformal Coating of Mammalian Cells Immobilized Onto Magnetically Driven Beads Tissue Engineering. Nov-Dec, 2005 | Pubmed ID: 16411825 Poloxamine Hydrogels with a Quaternary Ammonium Modification to Improve Cell Attachment Journal of Biomedical Materials Research. Part A. Nov, 2005 | Pubmed ID: 16059894 Semi-synthetic Collagen/poloxamine Matrices for Tissue Engineering Biomaterials. Dec, 2005 | Pubmed ID: 16023714 Endotoxin: the Uninvited Guest Biomaterials. Dec, 2005 | Pubmed ID: 16019062 In Vivo Recognition by the Host Adaptive Immune System of Microencapsulated Xenogeneic Cells Transplantation. Nov, 2004 | Pubmed ID: 15599309 Expression of Matrix Metalloproteinase-2 and -9 in Exudates Associated with Polydimethyl Siloxane and Gelatin Tubes Implanted in Mice Journal of Biomedical Materials Research. Part A. Nov, 2004 | Pubmed ID: 15386490 Poly(methylidene Malonate 2.1.2) Nanoparticles: a Biocompatible Polymer That Enhances Peri-adventitial Adenoviral Gene Delivery Journal of Controlled Release : Official Journal of the Controlled Release Society. Aug, 2004 | Pubmed ID: 15313000 Biomaterial-associated Thrombosis: Roles of Coagulation Factors, Complement, Platelets and Leukocytes Biomaterials. Nov, 2004 | Pubmed ID: 15147815 Reaction of Poly(acrylamide-co-vinylamine) with Tresyl-PEG in the Presence of PC12 Cells Biomaterials. Feb, 2003 | Pubmed ID: 12423598 Functional Assessment of Engineered Tissues and Elements of Tissue Design: Breakout Session Summary Annals of the New York Academy of Sciences. Jun, 2002 | Pubmed ID: 12081902 Functional Considerations in Tissue-engineering Whole Organs Annals of the New York Academy of Sciences. Jun, 2002 | Pubmed ID: 12081898 Fabrication of Micro-tissues using Modules of Collagen Gel Containing Cells M. Dean Chamberlain1, Mark J. Butler1, Ema C. Ciucurel1, Lindsay E. Fitzpatrick2, Omar F. Khan1, Brendan M. Leung2, Chuen Lo1, Ritesh Patel2, Alexandra Velchinskaya2, Derek N. Voice2, Michael V. Sefton1 1Institute of Biomaterials and Biomedical Engineering / Department of Chemical Engineering and Applied Chemistry, University of Toronto, 2Institute of Biomaterials and Biomedical Engineering, University of Toronto JoVE 2177 Bioengineering
Fabrication of Micro-tissues using Modules of Collagen Gel Containing Cells M. Dean Chamberlain1, Mark J. Butler1, Ema C. Ciucurel1, Lindsay E. Fitzpatrick2, Omar F. Khan1, Brendan M. Leung2, Chuen Lo1, Ritesh Patel2, Alexandra Velchinskaya2, Derek N. Voice2, Michael V. Sefton1 1Institute of Biomaterials and Biomedical Engineering / Department of Chemical Engineering and Applied Chemistry, University of Toronto, 2Institute of Biomaterials and Biomedical Engineering, University of Toronto JoVE 2177 Bioengineering
