Michael Hutchinson Department of Neurology St. Vincent's University Hospital Biography Publications Institution JoVE Articles Michael Hutchinson has not added a biography. If you are Michael Hutchinson and would like to personalize this page please email our Author Liaison for assistance. Publications Temporal Discrimination: Mechanisms and Relevance to Adult-Onset Dystonia Frontiers in Neurology. 2017 | Pubmed ID: 29234300 The Premotor Syndrome of Cervical Dystonia: Disordered Processing of Salient Environmental Stimuli Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2017 | Pubmed ID: 29205495 Disrupted Superior Collicular Activity May Reveal Cervical Dystonia Disease Pathomechanisms Scientific Reports. Dec, 2017 | Pubmed ID: 29196716 Practice Does Not Make Perfect: Temporal Discrimination in Musicians with and Without Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2017 | Pubmed ID: 29076564 Effects of Vitamin D3 in Clinically Isolated Syndrome and Healthy Control Participants: A Double-blind Randomised Controlled Trial Multiple Sclerosis Journal - Experimental, Translational and Clinical. Jul-Sep, 2017 | Pubmed ID: 28975037 Immediate Thrombocytopenia at Time of Alemtuzumab Infusion for Multiple Sclerosis - Not Always Self-limiting, Fully Reversible or Predictable Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2017 | Pubmed ID: 28661220 Treatment Effectiveness of Alemtuzumab Compared with Natalizumab, Fingolimod, and Interferon Beta in Relapsing-remitting Multiple Sclerosis: a Cohort Study The Lancet. Neurology. Apr, 2017 | Pubmed ID: 28209331 A Comparison of Stimulus Presentation Methods in Temporal Discrimination Testing Physiological Measurement. Feb, 2017 | Pubmed ID: 28099169 Menstrual Cycle and the Temporal Discrimination Threshold Physiological Measurement. Feb, 2017 | Pubmed ID: 28099161 Marta Elian: Obituary Multiple Sclerosis (Houndmills, Basingstoke, England). Mar, 2017 | Pubmed ID: 27956560 Long-term Effects of Delayed-release Dimethyl Fumarate in Multiple Sclerosis: Interim Analysis of ENDORSE, a Randomized Extension Study Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2017 | Pubmed ID: 27207449 Integrated Multidisciplinary Clinics Should Be the Gold Standard in Managing Progressive MS - Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Aug, 2016 | Pubmed ID: 27225676 All Relapsing Multiple Sclerosis Patients Should Be Managed at a Specialist Clinic - Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). 06, 2016 | Pubmed ID: 27207461 A Useful Annual Review of Cognition in Relapsing MS is Beyond Most Neurologists - Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). 05, 2016 | Pubmed ID: 27048309 Exploring the Unknown: Electrophysiological and Behavioural Measures of Visuospatial Learning The European Journal of Neuroscience. May, 2016 | Pubmed ID: 26840918 Modeling the Course and Outcomes of MS is Statistical Twaddle--Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2016 | Pubmed ID: 26830395 Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis PloS One. 2016 | Pubmed ID: 26726800 Neural Correlates of Abnormal Sensory Discrimination in Laryngeal Dystonia NeuroImage. Clinical. 2016 | Pubmed ID: 26693398 Sun Exposure is an Environmental Factor for the Development of Blepharospasm Journal of Neurology, Neurosurgery, and Psychiatry. Apr, 2016 | Pubmed ID: 25904812 Age-Related Sexual Dimorphism in Temporal Discrimination and in Adult-Onset Dystonia Suggests GABAergic Mechanisms Frontiers in Neurology. 2015 | Pubmed ID: 26696957 Neurodegeneration in Multiple Sclerosis is a Process Separate from Inflammation: No Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2015 | Pubmed ID: 26515290 Multiple Sclerosis Relapse Phenotype is an Important, Neglected Determinant of Disease-outcome: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2015 | Pubmed ID: 26438305 The Only Certain Measure of the Effectiveness of Multiple Sclerosis Therapy is Cerebrospinal Neurofilament Level: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2015 | Pubmed ID: 26242693 Young Women Do It Better: Sexual Dimorphism in Temporal Discrimination Frontiers in Neurology. 2015 | Pubmed ID: 26217303 Symptomatic Therapy in Multiple Sclerosis: Big Pharma Should Do More--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jul, 2015 | Pubmed ID: 26084346 A Network Meta-Analysis of Efficacy and Evaluation of Safety of Subcutaneous Pegylated Interferon Beta-1a Versus Other Injectable Therapies for the Treatment of Relapsing-Remitting Multiple Sclerosis PloS One. 2015 | Pubmed ID: 26039748 Unmet Needs of Multiple Sclerosis Patients in the Community Multiple Sclerosis and Related Disorders. Mar, 2015 | Pubmed ID: 25787190 Efficacy of Delayed-release Dimethyl Fumarate in Relapsing-remitting Multiple Sclerosis: Integrated Analysis of the Phase 3 Trials Annals of Clinical and Translational Neurology. Feb, 2015 | Pubmed ID: 25750916 Effects of Delayed-release Dimethyl Fumarate on MRI Measures in the Phase 3 CONFIRM Study Neurology. Mar, 2015 | Pubmed ID: 25681448 Any Evident MRI T2 Lesion Activity Should Guide Change of Therapy in Multiple Sclerosis--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2015 | Pubmed ID: 25623247 We Can Compare the Relative Efficacy Multiple Sclerosis Medications by Examining the Results of Independent Clinical Trials: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2015 | Pubmed ID: 25533303 An Evaluation of the Role of Environmental Factors in the Disease Penetrance of Cervical Dystonia Journal of Neurology, Neurosurgery, and Psychiatry. Mar, 2015 | Pubmed ID: 24963124 Future Placebo-controlled Trials of Disease Modifying Therapy in Relapsing Multiple Sclerosis Would Be Unethical: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). 08, 2014 | Pubmed ID: 27352435 The Best Clinical Paper of 2013: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2014 | Pubmed ID: 27352431 Managing Flushing and Gastrointestinal Events Associated with Delayed-release Dimethyl Fumarate: Experiences of an International Panel Multiple Sclerosis and Related Disorders. Jul, 2014 | Pubmed ID: 25877064 The Best Basic Science Paper in Multiple Sclerosis in 2013: Disease Specific Molecular Events in Cortical Multiple Sclerosis Lesions Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2014 | Pubmed ID: 25392336 Multiparity in Women with Multiple Sclerosis Causes Less Long-term Disability: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2014 | Pubmed ID: 25344548 Spinal Cord MRI Should Always Be Performed in Clinically Isolated Syndrome Patients: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2014 | Pubmed ID: 25326506 Optical Coherence Tomography Should Be Part of the Routine Monitoring of Patients with Multiple Sclerosis: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2014 | Pubmed ID: 25160124 A Headset Method for Measuring the Visual Temporal Discrimination Threshold in Cervical Dystonia Tremor and Other Hyperkinetic Movements (New York, N.Y.). 2014 | Pubmed ID: 25126450 Epidemiology of Wilson's Disease in Ireland Movement Disorders : Official Journal of the Movement Disorder Society. Oct, 2014 | Pubmed ID: 25112974 Cervical Dystonia: a Disorder of the Midbrain Network for Covert Attentional Orienting Frontiers in Neurology. 2014 | Pubmed ID: 24803911 MRI Measures Should Be a Primary Outcome Endpoint in Phase III Randomised Controlled Trials in Multiple Sclerosis: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Mar, 2014 | Pubmed ID: 24589687 Temporal Discrimination, a Cervical Dystonia Endophenotype: Penetrance and Functional Correlates Movement Disorders : Official Journal of the Movement Disorder Society. May, 2014 | Pubmed ID: 24482092 Dexterity Training Improves Manual Precision in Patients Affected by Essential Tremor Archives of Physical Medicine and Rehabilitation. Apr, 2014 | Pubmed ID: 24275064 Efficacy and Safety of BG-12 (dimethyl Fumarate) and Other Disease-modifying Therapies for the Treatment of Relapsing-remitting Multiple Sclerosis: a Systematic Review and Mixed Treatment Comparison Current Medical Research and Opinion. Apr, 2014 | Pubmed ID: 24195574 Evoked Potentials Are of Little Use in the Diagnosis or Monitoring of MS: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2013 | Pubmed ID: 24277734 Epstein-Barr Virus is a Necessary Causative Agent in the Pathogenesis of Multiple Sclerosis: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2013 | Pubmed ID: 24218488 One Can Prevent Post-partum MS Relapses by Exclusive Breast Feeding: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2013 | Pubmed ID: 24132003 The Endophenotype and the Phenotype: Temporal Discrimination and Adult-onset Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Nov, 2013 | Pubmed ID: 24108447 Dose-related Effects of Vitamin D on Immune Responses in Patients with Clinically Isolated Syndrome and Healthy Control Participants: Study Protocol for an Exploratory Randomized Double- Blind Placebo-controlled Trial Trials. Aug, 2013 | Pubmed ID: 23981773 Clinical Efficacy of BG-12 (dimethyl Fumarate) in Patients with Relapsing-remitting Multiple Sclerosis: Subgroup Analyses of the CONFIRM Study Journal of Neurology. Sep, 2013 | Pubmed ID: 23749293 Funding CCSVI Research Is/was a Waste of Valuable Time, Money and Intellectual Energy: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2013 | Pubmed ID: 23712526 CSF Oligoclonal Bands Are Important in the Diagnosis of Multiple Sclerosis, Unreasonably Downplayed by the McDonald Criteria 2010: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). May, 2013 | Pubmed ID: 23658237 The Best Clinical Paper on Multiple Sclerosis in 2012: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Apr, 2013 | Pubmed ID: 23599183 If I Had CIS with MRI Diagnostic of MS, I Would Take Vitamin D 10,000 IU Daily: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Feb, 2013 | Pubmed ID: 23388851 The Only Way to Manage Neurodegeneration in MS is to Prevent It with Effective Anti-inflammatory Therapy: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2012 | Pubmed ID: 23235778 Treat Patients with Radiologically Isolated Syndrome when the MRI Brain Scan Shows Dissemination in Time: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2012 | Pubmed ID: 23100525 Only Low Frequency Event-related EEG Activity is Compromised in Multiple Sclerosis: Insights from an Independent Component Clustering Analysis PloS One. 2012 | Pubmed ID: 23029079 Rehabilitation Therapy in MS: a Short-term, Expensive, Placebo: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2012 | Pubmed ID: 23014628 Industrial Pharmaceutical Drug Research Has Done More for the Health of People with MS Than Academic Neurologists: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2012 | Pubmed ID: 22936684 Deaths and Disability from Natalizumab Are No Longer Tolerable: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Aug, 2012 | Pubmed ID: 22807472 There is No Such Thing As a Mild MS Relapse. The Mild Relapse is an Anglo-Saxon Delusion - Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jul, 2012 | Pubmed ID: 22740606 We Are About to Cure MS in the Next 10 Years, Even Though We Do Not Know Its Cause: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2012 | Pubmed ID: 22619227 The Neurologist's Dilemma: MS is a Grey Matter Disease That Standard Clinical and MRI Measures Cannot Assess Adequately--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). May, 2012 | Pubmed ID: 22547413 Do Not Treat from CIS Onset: Evaluate Disease Course and Prognosis First--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Apr, 2012 | Pubmed ID: 22473502 In Assessing Multiple Sclerosis Disease Activity Patient Report Measures Are a Waste of Time: Cut to the MRI Scan!--Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Mar, 2012 | Pubmed ID: 22383438 Truly Benign Multiple Sclerosis is Rare: Let's Stop Fooling Ourselves--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2012 | Pubmed ID: 22146606 Using Atypical Symptoms and Red Flags to Identify Non-demyelinating Disease Journal of Neurology, Neurosurgery, and Psychiatry. Jan, 2012 | Pubmed ID: 21849338 Relapses Do Not Matter in Relation to Long-term Disability: Commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2011 | Pubmed ID: 22130599 The Major Cause of Multiple Sclerosis is Environmental: Genetics Has a Minor Role--commentary Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2011 | Pubmed ID: 21980152 Controversies in Multiple Sclerosis: a Series of Debates Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2011 | Pubmed ID: 21980149 Translation Initiator EIF4G1 Mutations in Familial Parkinson Disease American Journal of Human Genetics. Sep, 2011 | Pubmed ID: 21907011 Sporadic Adult Onset Primary Torsion Dystonia is a Genetic Disorder by the Temporal Discrimination Test Brain : a Journal of Neurology. Sep, 2011 | Pubmed ID: 21840890 Obituary Multiple Sclerosis (Houndmills, Basingstoke, England). May, 2010 | Pubmed ID: 28071148 Natalizumab Therapy of Multiple Sclerosis Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Oct, 2010 | Pubmed ID: 20874255 Clinically Isolated Syndrome: a Protected Zone for Trials of New Therapies? Multiple Sclerosis (Houndmills, Basingstoke, England). Jun, 2010 | Pubmed ID: 20427416 Comparing Endophenotypes in Adult-onset Primary Torsion Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Jan, 2010 | Pubmed ID: 19938165 Sensory Ataxic Neuropathy Dysarthria and Ophthalmoparesis (SANDO) in a Sibling Pair with a Homozygous P.A467T POLG Mutation Muscle & Nerve. Feb, 2010 | Pubmed ID: 19813183 Discontinuing Disease-modifying Therapy in Progressive Multiple Sclerosis: Can We Stop What We Have Started? Multiple Sclerosis (Houndmills, Basingstoke, England). Dec, 2009 | Pubmed ID: 19995848 Reactivation of BK Polyomavirus in Patients with Multiple Sclerosis Receiving Natalizumab Therapy Journal of Neurovirology. Sep, 2009 | Pubmed ID: 19670070 Phenotypic Diversity Associated with the Mitochondrial M.8313G>A Point Mutation Muscle & Nerve. Oct, 2009 | Pubmed ID: 19618438 Predicting and Preventing the Future: Actively Managing Multiple Sclerosis Practical Neurology. Jun, 2009 | Pubmed ID: 19448055 Striatal Morphology Correlates with Sensory Abnormalities in Unaffected Relatives of Cervical Dystonia Patients Journal of Neurology. Aug, 2009 | Pubmed ID: 19353218 The Efficacy of Natalizumab in Patients with Relapsing Multiple Sclerosis: Subgroup Analyses of AFFIRM and SENTINEL Journal of Neurology. Mar, 2009 | Pubmed ID: 19308305 Identification of the SPG15 Gene, Encoding Spastizin, As a Frequent Cause of Complicated Autosomal-recessive Spastic Paraplegia, Including Kjellin Syndrome American Journal of Human Genetics. Apr, 2008 | Pubmed ID: 18394578 REEP1 Mutation Spectrum and Genotype/phenotype Correlation in Hereditary Spastic Paraplegia Type 31 Brain : a Journal of Neurology. Apr, 2008 | Pubmed ID: 18321925 Natalizumab: A New Treatment for Relapsing Remitting Multiple Sclerosis Therapeutics and Clinical Risk Management. Jun, 2007 | Pubmed ID: 18360634 Molding the Sensory Cortex: Spatial Acuity Improves After Botulinum Toxin Treatment for Cervical Dystonia Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2007 | Pubmed ID: 17960812 Sporadic Adult Onset Dystonia: Sensory Abnormalities As an Endophenotype in Unaffected Relatives Journal of Neurology, Neurosurgery, and Psychiatry. Sep, 2007 | Pubmed ID: 17702779 Outcome of Beta-interferon Treatment in Relapsing-remitting Multiple Sclerosis: a Bayesian Analysis Journal of Neurology. Nov, 2007 | Pubmed ID: 17694348 The Patient Knows Best: Significant Change in the Physical Component of the Multiple Sclerosis Impact Scale (MSIS-29 Physical) Journal of Neurology, Neurosurgery, and Psychiatry. Aug, 2007 | Pubmed ID: 17332049 Population Frequency of HLA Haplotypes Contributes to the Prevalence Difference of Multiple Sclerosis in Ireland Journal of Neurology. Oct, 2005 | Pubmed ID: 16158194 Inherited Myoclonus-dystonia and Epilepsy: Further Evidence of an Association? Movement Disorders : Official Journal of the Movement Disorder Society. Dec, 2004 | Pubmed ID: 15389977 Familial Adolescent-onset Scoliosis and Later Segmental Dystonia in an Irish Family Journal of Neurology. Jul, 2004 | Pubmed ID: 15258787 Cervical Dystonia Following Peripheral Trauma--a Case-control Study Journal of Neurology. Feb, 2004 | Pubmed ID: 14991348 Further Evidence of Dementia in SPG4-linked Autosomal Dominant Hereditary Spastic Paraplegia Neurology. Feb, 2004 | Pubmed ID: 14872021 Meting en analyse van de drempel van de temporele discriminatie toegepast op cervicale dystonie Rebecca B Beck*1, Eavan M McGovern*1,2,3, John S Butler4, Dorina Birsanu1, Brendan Quinlivan1, Ines Beiser1,2,3, Shruti Narasimham1, Sean O'Riordan2,3, Michael Hutchinson2,3, Richard B Reilly1,5 1School of Engineering, Trinity College Dublin, The University of Dublin, 2Department of Neurology, St. Vincent's University Hospital, 3School of Medicine and Medical Sciences, University College Dublin, 4School of Mathematical Sciences, Dublin Institute of Technology, 5School of Medicine Trinity College Dublin, The University of Dublin JoVE 56310 Neuroscience
Meting en analyse van de drempel van de temporele discriminatie toegepast op cervicale dystonie Rebecca B Beck*1, Eavan M McGovern*1,2,3, John S Butler4, Dorina Birsanu1, Brendan Quinlivan1, Ines Beiser1,2,3, Shruti Narasimham1, Sean O'Riordan2,3, Michael Hutchinson2,3, Richard B Reilly1,5 1School of Engineering, Trinity College Dublin, The University of Dublin, 2Department of Neurology, St. Vincent's University Hospital, 3School of Medicine and Medical Sciences, University College Dublin, 4School of Mathematical Sciences, Dublin Institute of Technology, 5School of Medicine Trinity College Dublin, The University of Dublin JoVE 56310 Neuroscience