Michael Kharas

Publications

• The Lin28/let-7 Axis Regulates Glucose Metabolism
  Cell. Sep, 2011  |   Pubmed ID: 21962509
• From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond
  Genes & Cancer. Dec, 2010  |   Pubmed ID: 21779439
• Musashi-2 Regulates Normal Hematopoiesis and Promotes Aggressive Myeloid Leukemia
  Nature Medicine. Aug, 2010  |   Pubmed ID: 20616797
• Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells
  Cancer Cell. Jun, 2010  |   Pubmed ID: 20541703
• Akt: a Double-edged Sword for Hematopoietic Stem Cells
  Cell Cycle (Georgetown, Tex.). Apr, 2010  |   Pubmed ID: 20234178
• Constitutively Active AKT Depletes Hematopoietic Stem Cells and Induces Leukemia in Mice
  Blood. Feb, 2010  |   Pubmed ID: 20008787
• Hedgehog Signaling is Dispensable for Adult Murine Hematopoietic Stem Cell Function and Hematopoiesis
  Cell Stem Cell. Jun, 2009  |   Pubmed ID: 19497284
• Constitutive JAK3 Activation Induces Lymphoproliferative Syndromes in Murine Bone Marrow Transplantation Models
  Blood. Mar, 2009  |   Pubmed ID: 19139084
• Ablation of PI3K Blocks BCR-ABL Leukemogenesis in Mice, and a Dual PI3K/mTOR Inhibitor Prevents Expansion of Human BCR-ABL+ Leukemia Cells
  The Journal of Clinical Investigation. Sep, 2008  |   Pubmed ID: 18704194
• Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-induced Polycythemia Vera
  Cancer Cell. Apr, 2008  |   Pubmed ID: 18394554
• KLF4 is a FOXO Target Gene That Suppresses B Cell Proliferation
  International Immunology. May, 2008  |   Pubmed ID: 18375530
• Measuring Phosphorylated Akt and Other Phosphoinositide 3-kinase-regulated Phosphoproteins in Primary Lymphocytes
  Methods in Enzymology. 2007  |   Pubmed ID: 17954246
• T-cell Function is Partially Maintained in the Absence of Class IA Phosphoinositide 3-kinase Signaling
  Blood. Apr, 2007  |   Pubmed ID: 17164340
• KLF4 Suppresses Transformation of Pre-B Cells by ABL Oncogenes
  Blood. Jan, 2007  |   Pubmed ID: 16954505
• Sjögren's Syndrome-like Disease in Mice with T Cells Lacking Class 1A Phosphoinositide-3-kinase
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17071741
• S6 Kinase 2 Potentiates Interleukin-3-driven Cell Proliferation
  Journal of Leukocyte Biology. Dec, 2005  |   Pubmed ID: 16204634
• ABL Oncogenes and Phosphoinositide 3-kinase: Mechanism of Activation and Downstream Effectors
  Cancer Research. Mar, 2005  |   Pubmed ID: 15781610
• Optimal B-cell Proliferation Requires Phosphoinositide 3-kinase-dependent Inactivation of FOXO Transcription Factors
  Blood. Aug, 2004  |   Pubmed ID: 15069012
• Phosphoinositide 3-kinase Signaling is Essential for ABL Oncogene-mediated Transformation of B-lineage Cells
  Blood. Jun, 2004  |   Pubmed ID: 14976048
• The Avian ChB6 Alloantigen Induces Apoptosis in DT40 B Cells
  Cellular Immunology. Dec, 2003  |   Pubmed ID: 14962497