Other Publications (1)
Articles by Miguel Tillo in JoVE
Mouse Hindbrain Ex Vivo Culture to Study Facial Branchiomotor Neuron Migration Miguel Tillo1, Quenten Schwarz1,2, Christiana Ruhrberg1 1UCL Institute of Ophthalmology, University College London, 2Department of Human Immunology, Centre for Cancer Biology, South Australia Embryonic neurons are born in the ventricular zone of the neural tube, but migrate to reach appropriate targets. Facial branchiomotor (FBM) neurons are a useful model to study neuronal migration. This protocol describes the wholemount ex vivo culture of mouse embryo hindbrains to investigate mechanisms that regulate FBM migration.
Other articles by Miguel Tillo on PubMed
Emerging Roles for Semaphorins and VEGFs in Synaptogenesis and Synaptic Plasticity Cell Adhesion & Migration. Nov-Dec, 2012 | Pubmed ID: 23076132 Synapse formation, maintenance and plasticity are critical for the correct function of the nervous system and its target organs. During development, these processes enable the establishment of appropriate neural circuits. During adulthood, they allow adaptation to both physiological and environmental changes. In this review, we discuss emerging roles for two families of classical axon and vascular guidance cues in synaptogenesis and synaptic plasticity, the semaphorins and the vascular endothelial growth factors (VEGFs). Their contribution to synapse formation and function add a new facet to the spectrum of overlapping and complementary roles for these molecules in development, adulthood and disease.