Articles by Mikaela C. Murph in JoVE

• Genetics

  
  Manipulation of Ploidy in Caenorhabditis elegans Erlyana K. Clarke¹, Katherine A. Rivera Gomez^1,2, Zaki Mustachi¹, Mikaela C. Murph^1,3, Mara Schvarzstein^{1,2,3 1}Brooklyn College, Biology Department, City University of New York, ²The Graduate Center, Biology Department, City University of New York, ³Advanced Science Research Center, City University of New York This method allows for the generation of tetraploid and triploid Caenorhabditis nematodes from any diploid strain. Polyploid strains generated by this method have been used to study chromosome interactions in meiotic prophase, and this method is useful for examining important basic questions in cell, developmental, evolutionary, and cancer biology.