Mingyao Liu Latner Thoracic Research Laboratories, Toronto General Hospital Research Institute University Health Network Biography Publications Institution JoVE Articles Mingyao Liu has not added a biography. If you are Mingyao Liu and would like to personalize this page please email our Author Liaison for assistance. Publications Donor IL-17 Receptor A Regulates LPS-potentiated Acute and Chronic Murine Lung Allograft Rejection JCI Insight. Nov, 2023 | Pubmed ID: 37937643 Acellular Ex Vivo Lung Perfusate Silences Pro-inflammatory Signaling in Human Lung Endothelial and Epithelial Cells Journal of Translational Medicine. Oct, 2023 | Pubmed ID: 37845763 Applications and Safety of Gold Nanoparticles As Therapeutic Devices in Clinical Trials Journal of Pharmaceutical Analysis. Sep, 2023 | Pubmed ID: 37842655 Necroptosis in Organ Transplantation: Mechanisms and Potential Therapeutic Targets Cells. Sep, 2023 | Pubmed ID: 37759518 De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models International Journal of Molecular Sciences. Aug, 2023 | Pubmed ID: 37685927 A Machine-learning Approach to Human Ex Vivo Lung Perfusion Predicts Transplantation Outcomes and Promotes Organ Utilization Nature Communications. Aug, 2023 | Pubmed ID: 37558674 Identification of Regional Variation in Gene Expression and Inflammatory Proteins in Donor Lung Tissue and Ex vivo Lung Perfusate The Journal of Thoracic and Cardiovascular Surgery. Jul, 2023 | Pubmed ID: 37482240 Time to Extubation for Lung Transplant Recipients Represents a Pragmatic End-point to Guide the Development of Prognostic Tests The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jul, 2023 | Pubmed ID: 37406839 Mesenchymal Stromal Cell Therapy in Lung Transplantation Bioengineering (Basel, Switzerland). Jun, 2023 | Pubmed ID: 37370659 A Cell-free Tissue-engineered Tracheal Substitute with Sequential Cytokine Release Maintained Airway Opening in a Rabbit Tracheal Full Circumferential Defect Model Biomaterials. Sep, 2023 | Pubmed ID: 37352607 A Novel Tissue Preservation and Transport Solution As a Substitute for Formalin Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2023 | Pubmed ID: 37321542 Immunomodulation of the Donor Lung with CRISPR-mediated Activation of IL-10 Expression The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Oct, 2023 | Pubmed ID: 37315746 Evaluating the Impact of Ex Vivo Lung Perfusion on Organ Transplantation: A Retrospective Cohort Study Annals of Surgery. Aug, 2023 | Pubmed ID: 37073734 Alpha-1-antitrypsin Safely Promotes Rapid Recovery of Pigs After Lung Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2023 | Pubmed ID: 37004914 Defining and Targeting Tumor-associated Macrophages in Malignant Mesothelioma Proceedings of the National Academy of Sciences of the United States of America. Feb, 2023 | Pubmed ID: 36821580 Triaging Donor Lungs Based on a Microaspiration Signature That Predicts Adverse Recipient Outcome The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Apr, 2023 | Pubmed ID: 36710092 L-alanyl-L-glutamine Modified Perfusate Improves Human Lung Cell Functions and Extend Porcine Ex Vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Feb, 2023 | Pubmed ID: 36411189 Determining the Impact of Ex-vivo Lung Perfusion on Hospital Costs for Lung Transplantation: A Retrospective Cohort Study The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2023 | Pubmed ID: 36411188 Altered Purine Metabolism at Reperfusion Affects Clinical Outcome in Lung Transplantation Thorax. Mar, 2023 | Pubmed ID: 35450941 Evaluation of 10°C As the Optimal Storage Temperature for Aspiration-injured Donor Lungs in a Large Animal Transplant Model The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Dec, 2022 | Pubmed ID: 36216693 A Biomarker Assay to Risk-stratify Patients with Symptoms of Respiratory Tract Infection The European Respiratory Journal. Dec, 2022 | Pubmed ID: 36104292 Successful 3-day Lung Preservation Using a Cyclic Normothermic Ex Vivo Lung Perfusion Strategy EBioMedicine. Sep, 2022 | Pubmed ID: 35952495 Cell Death and Ischemia-reperfusion Injury in Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Aug, 2022 | Pubmed ID: 35710485 Interferon-stimulated and Metallothionein-expressing Macrophages Are Associated with Acute and Chronic Allograft Dysfunction After Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2022 | Pubmed ID: 35691795 Near-infrared Fluorescence Imaging During Ex vivo Lung Perfusion: Noninvasive Real-time Evaluation of Regional Lung Perfusion and Edema The Journal of Thoracic and Cardiovascular Surgery. Nov, 2022 | Pubmed ID: 35382935 Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice Cells. Mar, 2022 | Pubmed ID: 35326426 Ex Vivo Enzymatic Treatment Converts Blood Type A Donor Lungs into Universal Blood Type Lungs Science Translational Medicine. Feb, 2022 | Pubmed ID: 35171649 Proteomics, Brain Death, and Organ Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2022 | Pubmed ID: 35016814 Pathogenesis of Multinodular Goiter in Elderly XB130-Deficient Mice: Alteration of Thyroperoxidase Affinity with Iodide and Hydrogen Peroxide Thyroid : Official Journal of the American Thyroid Association. Apr, 2022 | Pubmed ID: 34915750 Ex Vivo Treatment of Cytomegalovirus in Human Donor Lungs Using a Novel Chemokine-based Immunotoxin The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2022 | Pubmed ID: 34802874 Single-Cell Analysis Reveals EP4 As a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2022 | Pubmed ID: 34740924 XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes Thyroid : Official Journal of the American Thyroid Association. Feb, 2022 | Pubmed ID: 34652970 Delivery of Regulatory T-cells for Control of Alloimmune Priming in the Donor Lung The European Respiratory Journal. Apr, 2022 | Pubmed ID: 34475226 Engineered Mesenchymal Stromal Cell Therapy During Human Lung Lung Perfusion is Compromised by Acidic Lung Microenvironment Molecular Therapy. Methods & Clinical Development. Dec, 2021 | Pubmed ID: 34703841 Ischemia-Reperfusion Injury in a Simulated Lung Transplant Setting Differentially Regulates Transcriptomic Profiles Between Human Lung Endothelial and Epithelial Cells Cells. Oct, 2021 | Pubmed ID: 34685693 Static Lung Storage at 10°C Maintains Mitochondrial Health and Preserves Donor Organ Function Science Translational Medicine. Sep, 2021 | Pubmed ID: 34524862 XB130 Deficiency Causes Congenital Hypothyroidism in Mice Due to Disorganized Apical Membrane Structure and Function of Thyrocytes Thyroid : Official Journal of the American Thyroid Association. Nov, 2021 | Pubmed ID: 34470464 Surfactant Therapy in Lung Transplantation: A Systematic Review and Meta-analysis Transplantation Reviews (Orlando, Fla.). Dec, 2021 | Pubmed ID: 34224988 Inflammatory Responses in Lungs from Donation After Brain Death: Mechanisms and Potential Therapeutic Targets The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Sep, 2021 | Pubmed ID: 34167864 Predicting Donor Lung Acceptance for Transplant During Ex Vivo Lung Perfusion: The EX Vivo Lung PerfusIon PREdiction (EXPIRE) American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Nov, 2021 | Pubmed ID: 33872459 Use of Metabolomics to Identify Strategies to Improve and Prolong Ex Vivo Lung Perfusion for Lung Transplants The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2021 | Pubmed ID: 33849769 Tocilizumab in Treatment for Patients With COVID-19 JAMA Internal Medicine. Jul, 2021 | Pubmed ID: 33818614 ASO Author Reflections: CXCR7 and CXCL12 Expression As Biomarker in Patients with Esophageal Adenocarcinoma Annals of Surgical Oncology. Sep, 2021 | Pubmed ID: 33811307 Prediction of Donor Related Lung Injury in Clinical Lung Transplantation Using a Validated Ex Vivo Lung Perfusion Inflammation Score The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jul, 2021 | Pubmed ID: 33781664 Prognostic Impact of CXCR7 and CXCL12 Expression in Patients with Esophageal Adenocarcinoma Annals of Surgical Oncology. Sep, 2021 | Pubmed ID: 33709176 Using Nutrient-rich Solutions and Adding Multiple Cytoprotective Agents As New Strategies to Develop Lung Preservation Solutions American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2021 | Pubmed ID: 33688744 α1-Antitrypsin Deficiency and the Risk of COVID-19: an Urgent Call to Action The Lancet. Respiratory Medicine. Apr, 2021 | Pubmed ID: 33485406 Friend or Foe? ACE2 Inhibitors and GLP-1R Agonists in COVID-19 Treatment Obesity Medicine. Mar, 2021 | Pubmed ID: 33426364 Single-cell Analysis Reveals Transcriptomic Remodellings in Distinct Cell Types That Contribute to Human Prostate Cancer Progression Nature Cell Biology. Jan, 2021 | Pubmed ID: 33420488 Transcriptomic Investigation Reveals Donor-specific Gene Signatures in Human Lung Transplants The European Respiratory Journal. Apr, 2021 | Pubmed ID: 33122335 Strategies to Prolong Homeostasis of Ex vivo Perfused Lungs The Journal of Thoracic and Cardiovascular Surgery. Jun, 2021 | Pubmed ID: 32958268 Cell-free DNA in Human Ex vivo Lung Perfusate As a Potential Biomarker to Predict the Risk of Primary Graft Dysfunction in Lung Transplantation The Journal of Thoracic and Cardiovascular Surgery. Aug, 2021 | Pubmed ID: 32928548 Commentary: It's Time for Exosomes to Get the Limelight in Lung Transplant The Journal of Thoracic and Cardiovascular Surgery. Feb, 2021 | Pubmed ID: 32534751 Alpha-1 Antitrypsin for COVID-19 Treatment: Dual Role in Antiviral Infection and Anti-Inflammation Frontiers in Pharmacology. 2020 | Pubmed ID: 33362565 Safety Concerns Regarding Concomitant Use of Tocilizumab and Glucocorticoids in COVID-19 Patients Proceedings of the National Academy of Sciences of the United States of America. Dec, 2020 | Pubmed ID: 33184179 Veno-venous ECMO As a Platform to Evaluate Lung Lavage and Surfactant Replacement Therapy in an Animal Model of Severe ARDS Intensive Care Medicine Experimental. Oct, 2020 | Pubmed ID: 33108583 Ex Vivo Lung Perfusion for Donor Lung Assessment and Repair: a Review of Translational Interspecies Models American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2020 | Pubmed ID: 32996780 Letter to the Editor: Comment on GLP-1-based Drugs and COVID-19 Treatment Acta Pharmaceutica Sinica. B. Jul, 2020 | Pubmed ID: 32834951 Glucagon-like Peptide-1 Receptor Mediates the Beneficial Effect of Liraglutide in an Acute Lung Injury Mouse Model Involving the Thioredoxin-interacting Protein American Journal of Physiology. Endocrinology and Metabolism. Sep, 2020 | Pubmed ID: 32723174 An Extracellular Oxygen Carrier During Prolonged Pulmonary Preservation Improves Post-transplant Lung Function The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2020 | Pubmed ID: 32334946 Increased Arginase Expression and Decreased Nitric Oxide in Pig Donor Lungs After Normothermic Ex Vivo Lung Perfusion Biomolecules. Feb, 2020 | Pubmed ID: 32075026 Potential Therapeutic Targets for Lung Repair During Human Lung Perfusion The European Respiratory Journal. Apr, 2020 | Pubmed ID: 32060066 Pharmacokinetics, Tissue Distribution and Safety of Gold Nanoparticle/PKC Delta Inhibitor Peptide Hybrid in Rats Nanotoxicology. Apr, 2020 | Pubmed ID: 31852291 Chemokines and Their Receptors As Biomarkers in Esophageal Cancer Esophagus : Official Journal of the Japan Esophageal Society. Apr, 2020 | Pubmed ID: 31773415 Mesenchymal Stromal Cell Therapy During Ex Vivo Lung Perfusion Ameliorates Ischemia-reperfusion Injury in Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2019 | Pubmed ID: 31474491 A B Cell-dependent Pathway Drives Chronic Lung Allograft Rejection After Ischemia-reperfusion Injury in Mice American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Dec, 2019 | Pubmed ID: 31365766 Donor Prone Positioning Protects Lungs from Injury During Warm Ischemia American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Mar, 2019 | Pubmed ID: 30887696 XB130 Deficiency Enhances Carcinogen-induced Skin Tumorigenesis Carcinogenesis. Nov, 2019 | Pubmed ID: 30820526 Inactivating Hepatitis C Virus in Donor Lungs Using Light Therapies During Normothermic Ex Vivo Lung Perfusion Nature Communications. Jan, 2019 | Pubmed ID: 30696822 Lentiviral Interleukin-10 Gene Therapy: Safety and Questions The Journal of Thoracic and Cardiovascular Surgery. Feb, 2019 | Pubmed ID: 30669243 Neutrophil Extracellular Traps in Lung Perfusion Perfusate Predict the Clinical Outcome of Lung Transplant Recipients The European Respiratory Journal. Apr, 2019 | Pubmed ID: 30655281 Identification and Modulation of Microenvironment Is Crucial for Effective Mesenchymal Stromal Cell Therapy in Acute Lung Injury American Journal of Respiratory and Critical Care Medicine. May, 2019 | Pubmed ID: 30521764 Spectrum of Chronic Lung Allograft Pathology in a Mouse Minor-mismatched Orthotopic Lung Transplant Model American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jan, 2019 | Pubmed ID: 30378739 Intracellular Signal Transduction Pathways As Potential Drug Targets for Ischemia-reperfusion Injury in Lung Transplantation Journal of Thoracic Disease. Nov, 2018 | Pubmed ID: 30631528 Pig Lung Transplant Survival Model Nature Protocols. Aug, 2018 | Pubmed ID: 30072720 Ischemia-reperfusion Induces Death Receptor-independent Necroptosis Via Calpain-STAT3 Activation in a Lung Transplant Setting American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2018 | Pubmed ID: 30024306 A Novel Combined Ex vivo and In vivo Lentiviral Interleukin-10 Gene Delivery Strategy at the Time of Transplantation Decreases Chronic Lung Allograft Rejection in Mice The Journal of Thoracic and Cardiovascular Surgery. Sep, 2018 | Pubmed ID: 29937159 Inhibition of Regulated Necrosis Attenuates Receptor-interacting Protein Kinase 1-mediated Ischemia-reperfusion Injury After Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Oct, 2018 | Pubmed ID: 29907500 New Avenues for Nanoparticle-Related Therapies Nanoscale Research Letters. May, 2018 | Pubmed ID: 29740711 Upregulation of Alveolar Neutrophil Enzymes and Long Pentraxin-3 in Human Chronic Lung Allograft Dysfunction Subtypes The Journal of Thoracic and Cardiovascular Surgery. Jun, 2018 | Pubmed ID: 29573785 Organ Preservation: from the Past to the Future Acta Pharmacologica Sinica. May, 2018 | Pubmed ID: 29565040 Pentraxin 3 Deficiency Enhances Features of Chronic Rejection in a Mouse Orthotopic Lung Transplantation Model Oncotarget. Feb, 2018 | Pubmed ID: 29492210 Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion Transplantation. May, 2018 | Pubmed ID: 29470355 Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes Annals of Surgery. Jan, 2018 | Pubmed ID: 29240608 α-Anti-trypsin Improves Function of Porcine Donor Lungs During Ex-vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. May, 2018 | Pubmed ID: 29153638 Chronic Lung Injury and Impaired Pulmonary Function in a Mouse Model of Acid Ceramidase Deficiency American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2017 | Pubmed ID: 29167126 Donor Bronchial Wash Bile Acid and Suitability of Donor Lungs for Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Aug, 2017 | Pubmed ID: 28888765 Leucine-rich Repeat-containing G Protein-coupled Receptor 4 Facilitates Vesicular Stomatitis Virus Infection by Binding Vesicular Stomatitis Virus Glycoprotein The Journal of Biological Chemistry. Aug, 2017 | Pubmed ID: 28842478 Leucine-rich Repeat-containing G Protein Coupled Receptor 4 (Lgr4) is Necessary for Prostate Cancer Metastasis Via Epithelial-mesenchymal Transition The Journal of Biological Chemistry. Aug, 2017 | Pubmed ID: 28768769 Inhibition of Histone Deacetylases Sensitizes EGF Receptor-TK Inhibitor-resistant Non-small-cell Lung Cancer Cells to Erlotinib in Vitro and in Vivo British Journal of Pharmacology. Jul, 2017 | Pubmed ID: 28749535 Cytochrome P450 3A Selectively Affects the Pharmacokinetic Interaction Between Erlotinib and Docetaxel in Rats Biochemical Pharmacology. Jul, 2017 | Pubmed ID: 28716728 A Conducive Bioceramic/polymer Composite Biomaterial for Diabetic Wound Healing Acta Biomaterialia. Sep, 2017 | Pubmed ID: 28713016 Higher M30 and High Mobility Group Box 1 Protein Levels in Ex Vivo Lung Perfusate Are Associated with Primary Graft Dysfunction After Human Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2017 | Pubmed ID: 28689646 Virus-Triggered ATP Release Limits Viral Replication Through Facilitating IFN-β Production in a P2X7-Dependent Manner Journal of Immunology (Baltimore, Md. : 1950). Aug, 2017 | Pubmed ID: 28687662 CRISPR/Cas9 System: a Powerful Technology for in Vivo and Ex Vivo Gene Therapy Science China. Life Sciences. May, 2017 | Pubmed ID: 28534255 Elimination of GPR146-mediated Antiviral Function Through IRF3/HES1-signalling Pathway Immunology. Sep, 2017 | Pubmed ID: 28464285 Palmitoylated SCP1 is Targeted to the Plasma Membrane and Negatively Regulates Angiogenesis ELife. Mar, 2017 | Pubmed ID: 28440748 Novel Hemostatic Agents Based on Gelatin-microbial Transglutaminase Mix Science China. Life Sciences. Apr, 2017 | Pubmed ID: 28321657 Elevation of GPRC5A Expression in Colorectal Cancer Promotes Tumor Progression Through VNN-1 Induced Oxidative Stress International Journal of Cancer. Jun, 2017 | Pubmed ID: 28316092 Synthesis of Heterocyclic Ring-fused Tricyclic Diterpene Analogs As Novel Inhibitors of RANKL-induced Osteoclastogenesis and Bone Resorption European Journal of Medicinal Chemistry. May, 2017 | Pubmed ID: 28288319 Comprehensive Assessment of Cucurbitacin E Related Hepatotoxicity and Drug-drug Interactions Involving CYP3A and P-glycoprotein Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Mar, 2017 | Pubmed ID: 28257659 Ailanthone: a New Potential Drug for Castration-resistant Prostate Cancer Chinese Journal of Cancer. Mar, 2017 | Pubmed ID: 28257652 Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis Via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis Journal of Medicinal Chemistry. Mar, 2017 | Pubmed ID: 28218840 CRISPR Knockout Rat Cytochrome P450 3A1/2 Model for Advancing Drug Metabolism and Pharmacokinetics Research Scientific Reports. Feb, 2017 | Pubmed ID: 28218310 Ten Years of Achievements in Biological and Medical Sciences Science China. Life Sciences. 02, 2017 | Pubmed ID: 28215028 SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the T Helper 17/Regulatory T Cell Balance Molecular Pharmacology. May, 2017 | Pubmed ID: 28213589 A Novel Synthetic Small Molecule YF-452 Inhibits Tumor Growth Through Antiangiogenesis by Suppressing VEGF Receptor 2 Signaling Science China. Life Sciences. Feb, 2017 | Pubmed ID: 28194552 Sevoflurane Attenuates Ischemia-Reperfusion Injury in A Rat Lung Transplantation Model The Annals of Thoracic Surgery. May, 2017 | Pubmed ID: 28190546 Exploration and Analysis of Drug Modes of Action Through Feature Integration Molecular BioSystems. Jan, 2017 | Pubmed ID: 28092388 Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model Human Gene Therapy. Sep, 2017 | Pubmed ID: 28052693 Lung Lavage and Surfactant Replacement During Ex Vivo Lung Perfusion for Treatment of Gastric Acid Aspiration-Induced Donor Lung Injury The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. May, 2017 | Pubmed ID: 28041954 A Betulinic Acid Derivative SH479 Inhibits Collagen-induced Arthritis by Modulating T Cell Differentiation and Cytokine Balance Biochemical Pharmacology. Feb, 2017 | Pubmed ID: 27965071 Proteome-Scale Investigation of Protein Allosteric Regulation Perturbed by Somatic Mutations in 7,000 Cancer Genomes American Journal of Human Genetics. Jan, 2017 | Pubmed ID: 27939638 Heritable Expansion of the Genetic Code in Mouse and Zebrafish Cell Research. Feb, 2017 | Pubmed ID: 27934867 Design and Fabrication of a Dual-Photoelectrode Fuel Cell Towards Cost-Effective Electricity Production from Biomass ChemSusChem. Jan, 2017 | Pubmed ID: 27860457 A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids Basic & Clinical Pharmacology & Toxicology. Mar, 2017 | Pubmed ID: 27657920 Identification of Genes Involved in Breast Cancer Metastasis by Integrating Protein-Protein Interaction Information with Expression Data Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. Feb, 2017 | Pubmed ID: 27508455 Generation of Obese Rat Model by Transcription Activator-like Effector Nucleases Targeting the Leptin Receptor Gene Science China. Life Sciences. Feb, 2017 | Pubmed ID: 27225180 In Vitro and in Vivo Evaluation of Cucurbitacin E on Rat Hepatic CYP2C11 Expression and Activity Using LC-MS/MS Science China. Life Sciences. Feb, 2017 | Pubmed ID: 26354504 Ailanthone Targets P23 to Overcome MDV3100 Resistance in Castration-resistant Prostate Cancer Nature Communications. Dec, 2016 | Pubmed ID: 27959342 Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2016 | Pubmed ID: 27916995 Extracellular ADP Facilitates Monocyte Recruitment in Bacterial Infection Via ERK Signaling Cellular & Molecular Immunology. Nov, 2016 | Pubmed ID: 27867196 Stimulus-dependent Dissociation Between XB130 and Tks5 Scaffold Proteins Promotes Airway Epithelial Cell Migration Oncotarget. Nov, 2016 | Pubmed ID: 27835612 A Combination Therapy for KRAS-mutant Lung Cancer by Targeting Synthetic Lethal Partners of Mutant KRAS Chinese Journal of Cancer. 10, 2016 | Pubmed ID: 27793187 Endosomal PH Modulation by Peptide-gold Nanoparticle Hybrids Enables Potent Anti-inflammatory Activity in Phagocytic Immune Cells Biomaterials. Dec, 2016 | Pubmed ID: 27728817 3D Printing of Biomaterials with Mussel-inspired Nanostructures for Tumor Therapy and Tissue Regeneration Biomaterials. Dec, 2016 | Pubmed ID: 27728813 Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats Scientific Reports. Oct, 2016 | Pubmed ID: 27713523 Lgr4 is Crucial for Skin Carcinogenesis by Regulating MEK/ERK and Wnt/β-catenin Signaling Pathways Cancer Letters. Dec, 2016 | Pubmed ID: 27693558 A Self-restricted CRISPR System to Reduce Off-target Effects Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2016 | Pubmed ID: 27687135 Formulation of Hydrophobic Therapeutics with Self-assembling Peptide and Amino Acid: A New Platform for Intravenous Drug Delivery Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2016 | Pubmed ID: 27586187 Efficient Liver Repopulation of Transplanted Hepatocyte Prevents Cirrhosis in a Rat Model of Hereditary Tyrosinemia Type I Scientific Reports. Aug, 2016 | Pubmed ID: 27510266 Defeat Mutant KRAS with Synthetic Lethality Small GTPases. Jul, 2016 | Pubmed ID: 27463838 Mesenchymal Stem Cell Treatment is Associated with Decreased Perfusate Concentration of Interleukin-8 During Ex Vivo Perfusion of Donor Lungs After 18-hour Preservation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Oct, 2016 | Pubmed ID: 27444694 Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents Through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer Scientific Reports. Jul, 2016 | Pubmed ID: 27387652 Evaluation of the Inhibition Potential of Plumbagin Against Cytochrome P450 Using LC-MS/MS and Cocktail Approach Scientific Reports. Jun, 2016 | Pubmed ID: 27329697 Inhibiting Cytoplasmic Accumulation of HuR Synergizes Genotoxic Agents in Urothelial Carcinoma of the Bladder Oncotarget. Jul, 2016 | Pubmed ID: 27303922 Ccndbp1 is a New Positive Regulator of Skeletal Myogenesis Journal of Cell Science. Jul, 2016 | Pubmed ID: 27235421 Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors The Journal of Biological Chemistry. 07, 2016 | Pubmed ID: 27226600 Suppression of KRas-mutant Cancer Through the Combined Inhibition of KRAS with PLK1 and ROCK Nature Communications. May, 2016 | Pubmed ID: 27193833 Importance of Left Atrial Pressure During Ex Vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2016 | Pubmed ID: 27160496 Human α1-antitrypsin Improves Early Post-transplant Lung Function: Pre-clinical Studies in a Pig Lung Transplant Model The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jul, 2016 | Pubmed ID: 27095003 Gpr97 is Dispensable for Metabolic Syndrome but is Involved in Macrophage Inflammation in High-fat Diet-induced Obesity in Mice Scientific Reports. Apr, 2016 | Pubmed ID: 27089991 LGR4 is a Receptor for RANKL and Negatively Regulates Osteoclast Differentiation and Bone Resorption Nature Medicine. May, 2016 | Pubmed ID: 27064449 Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening Basic & Clinical Pharmacology & Toxicology. Oct, 2016 | Pubmed ID: 27060462 β-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis The Journal of Pharmacology and Experimental Therapeutics. Jun, 2016 | Pubmed ID: 27048660 XB130 Deficiency Enhances Lipopolysaccharide-induced Septic Response and Acute Lung Injury Oncotarget. May, 2016 | Pubmed ID: 27029000 Preparation of Copper-containing Bioactive Glass/eggshell Membrane Nanocomposites for Improving Angiogenesis, Antibacterial Activity and Wound Healing Acta Biomaterialia. 05, 2016 | Pubmed ID: 26965395 CRISPR/Cas9-mediated Somatic Correction of a Novel Coagulator Factor IX Gene Mutation Ameliorates Hemophilia in Mouse EMBO Molecular Medicine. 2016 | Pubmed ID: 26964564 Modified In Vivo Lung Perfusion for Local Chemotherapy: A Preclinical Study With Doxorubicin The Annals of Thoracic Surgery. Jun, 2016 | Pubmed ID: 26952295 Characterization of Novel Cytochrome P450 2E1 Knockout Rat Model Generated by CRISPR/Cas9 Biochemical Pharmacology. Apr, 2016 | Pubmed ID: 26947455 New Insights into the Androgen Biotransformation in Prostate Cancer: A Regulatory Network Among Androgen, Androgen Receptors and UGTs Pharmacological Research. Apr, 2016 | Pubmed ID: 26926093 Bortezomib Inhibits Giant Cell Tumor of Bone Through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption Molecular Cancer Therapeutics. May, 2016 | Pubmed ID: 26861247 Circulating Cell Death Biomarkers May Predict Survival in Human Lung Transplantation American Journal of Respiratory and Critical Care Medicine. Jul, 2016 | Pubmed ID: 26796350 Halofuginone Treatment Reduces Interleukin-17A and Ameliorates Features of Chronic Lung Allograft Dysfunction in a Mouse Orthotopic Lung Transplant Model The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Apr, 2016 | Pubmed ID: 26787621 TLR-Activated Gap Junction Channels Protect Mice Against Bacterial Infection Through Extracellular UDP Release Journal of Immunology (Baltimore, Md. : 1950). Feb, 2016 | Pubmed ID: 26783339 A Hybrid of Thiazolidinone with the Hydroxamate Scaffold for Developing Novel Histone Deacetylase Inhibitors with Antitumor Activities Organic & Biomolecular Chemistry. Feb, 2016 | Pubmed ID: 26732459 Annexin V Homodimer Protects Against Ischemia Reperfusion-induced Acute Lung Injury in Lung Transplantation The Journal of Thoracic and Cardiovascular Surgery. Mar, 2016 | Pubmed ID: 26725713 Insulin Sensitizes FGF21 in Glucose and Lipid Metabolisms Via Activating Common AKT Pathway Endocrine. Jun, 2016 | Pubmed ID: 26607153 Design, Synthesis and Anticancer Activities of Novel Otobain Derivatives Organic & Biomolecular Chemistry. Jan, 2016 | Pubmed ID: 26593226 Fibroblast Growth Factor 21 Attenuates Hepatic Fibrogenesis Through TGF-β/smad2/3 and NF-κB Signaling Pathways Toxicology and Applied Pharmacology. Jan, 2016 | Pubmed ID: 26592322 The Greedy Nature of Mutant RAS: a Boon for Drug Discovery Targeting Cancer Metabolism? Acta Biochimica Et Biophysica Sinica. Jan, 2016 | Pubmed ID: 26487443 Low-dose Computed Tomography Volumetry for Subtyping Chronic Lung Allograft Dysfunction The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2016 | Pubmed ID: 26342441 Extension of Donor Lung Preservation with Hypothermic Storage After Normothermic Ex Vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jan, 2016 | Pubmed ID: 26227444 Meet Our Associate Editor Current Molecular Medicine. 2015 | Pubmed ID: 26634985 Large Genomic Fragment Deletion and Functional Gene Cassette Knock-in Via Cas9 Protein Mediated Genome Editing in One-cell Rodent Embryos Scientific Reports. 2015 | Pubmed ID: 26620761 Inhibition of Osteoclastogenesis and Bone Resorption in Vitro and in Vivo by a Prenylflavonoid Xanthohumol from Hops Scientific Reports. Dec, 2015 | Pubmed ID: 26620037 Fractal Circuit Sensors Enable Rapid Quantification of Biomarkers for Donor Lung Assessment for Transplantation Science Advances. Aug, 2015 | Pubmed ID: 26601233 Using the Inherent Chemistry of the Endothelin-1 Peptide to Develop a Rapid Assay for Pre-transplant Donor Lung Assessment The Analyst. Dec, 2015 | Pubmed ID: 26548776 Hierarchically Micro-patterned Nanofibrous Scaffolds with a Nanosized Bio-glass Surface for Accelerating Wound Healing Nanoscale. Nov, 2015 | Pubmed ID: 26503372 XB130/Tks5 Scaffold Protein Interaction Regulates Src-mediated Cell Proliferation and Survival Molecular Biology of the Cell. Dec, 2015 | Pubmed ID: 26446840 A Fiber Bragg Grating Sensing Based Triaxial Vibration Sensor Sensors (Basel, Switzerland). Sep, 2015 | Pubmed ID: 26393616 LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity The Journal of Pharmacology and Experimental Therapeutics. Dec, 2015 | Pubmed ID: 26377911 XB130 Promotes Bronchioalveolar Stem Cell and Club Cell Proliferation in Airway Epithelial Repair and Regeneration Oncotarget. Oct, 2015 | Pubmed ID: 26360608 Altered Profile of Circulating Endothelial-Derived Microparticles in Ventilator-Induced Lung Injury Critical Care Medicine. Dec, 2015 | Pubmed ID: 26308427 Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms PloS One. 2015 | Pubmed ID: 26291700 A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice PloS One. 2015 | Pubmed ID: 26208278 Effective Delivery of a Rationally Designed Intracellular Peptide Drug with Gold Nanoparticle-peptide Hybrids Nanoscale. Aug, 2015 | Pubmed ID: 26151444 In Vivo Selection for Spine-derived Highly Metastatic Lung Cancer Cells is Associated with Increased Migration, Inflammation and Decreased Adhesion Oncotarget. Sep, 2015 | Pubmed ID: 26090868 Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids ACS Nano. Jul, 2015 | Pubmed ID: 26083966 Phenotypic Diversity Within a Pseudomonas Aeruginosa Population Infecting an Adult with Cystic Fibrosis Scientific Reports. Jun, 2015 | Pubmed ID: 26047320 Repression of Mammalian Target of Rapamycin Complex 1 Inhibits Intestinal Regeneration in Acute Inflammatory Bowel Disease Models Journal of Immunology (Baltimore, Md. : 1950). Jul, 2015 | Pubmed ID: 26026060 Long-Term Administration of Fibroblast Growth Factor 21 Prevents Chemically-Induced Hepatocarcinogenesis in Mice Digestive Diseases and Sciences. Oct, 2015 | Pubmed ID: 26003555 XB130 Translocation to Microfilamentous Structures Mediates NNK-induced Migration of Human Bronchial Epithelial Cells Oncotarget. Jul, 2015 | Pubmed ID: 25980441 5-Fluoruracil Blocked Giant Cell Tumor Progression by Suppressing Osteoclastogenesis Through NF-kappaB Signals and Blocking Angiogenesis Bone. Sep, 2015 | Pubmed ID: 25956534 Mechanical Stress and the Induction of Lung Fibrosis Via the Midkine Signaling Pathway American Journal of Respiratory and Critical Care Medicine. Aug, 2015 | Pubmed ID: 25945397 The Ubiquitination of Rag A GTPase by RNF152 Negatively Regulates MTORC1 Activation Molecular Cell. Jun, 2015 | Pubmed ID: 25936802 TAT Cell-penetrating Peptide Modulates Inflammatory Response and Apoptosis in Human Lung Epithelial Cells Drug Delivery and Translational Research. Jun, 2015 | Pubmed ID: 25916485 Lycorine is a Novel Inhibitor of the Growth and Metastasis of Hormone-refractory Prostate Cancer Oncotarget. Jun, 2015 | Pubmed ID: 25915156 The Role of the Endothelin-1 Pathway As a Biomarker for Donor Lung Assessment in Clinical Ex Vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2015 | Pubmed ID: 25907141 Design and Optimization of Hybrid of 2,4-diaminopyrimidine and Arylthiazole Scaffold As Anticancer Cell Proliferation and Migration Agents European Journal of Medicinal Chemistry. 2015 | Pubmed ID: 25899332 Inhibition of Breast Cancer Progression by a Novel Histone Deacetylase Inhibitor, LW479, by Down-regulating EGFR Expression British Journal of Pharmacology. Aug, 2015 | Pubmed ID: 25884486 Targeted Deletion of the Murine Lgr4 Gene Decreases Lens Epithelial Cell Resistance to Oxidative Stress and Induces Age-related Cataract Formation PloS One. 2015 | Pubmed ID: 25811370 Chemokine Receptors and Their Therapeutic Opportunities in Diseased Lung: Far Beyond Leukocyte Trafficking American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2015 | Pubmed ID: 25637606 Investigation of Cytochrome P450 Inhibitory Properties of Maslinic Acid, a Bioactive Compound from Olea Europaea L., and Its Structure-activity Relationship Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. Jan, 2015 | Pubmed ID: 25636872 PKCδ-iPLA2-PGE2-PPARγ Signaling Cascade Mediates TNF-α Induced Claudin 1 Expression in Human Lung Carcinoma Cells Cellular Signalling. Mar, 2015 | Pubmed ID: 25562426 Crystal Structure of LGR4-Rspo1 Complex: Insights into the Divergent Mechanisms of Ligand Recognition by Leucine-rich Repeat G-protein-coupled Receptors (LGRs) The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25480784 Long-acting Hypoglycemic Effects of PEGylated FGF21 and Insulin Glargine in Mice with Type 1 Diabetes Journal of Diabetes and Its Complications. Jan-Feb, 2015 | Pubmed ID: 25456819 Development of a Validated LC-MS/MS Method for the Determination of Ailanthone in Rat Plasma with Application to Pharmacokinetic Study Journal of Pharmaceutical and Biomedical Analysis. Jan, 2015 | Pubmed ID: 25433911 Inhibition of Tumor Growth by Polyarginine-fused Mutant Cytosine Deaminase Applied Biochemistry and Biotechnology. Feb, 2015 | Pubmed ID: 25416477 PubAngioGen: a Database and Knowledge for Angiogenesis and Related Diseases Nucleic Acids Research. Jan, 2015 | Pubmed ID: 25392416 Protein Expression Profiling Predicts Graft Performance in Clinical Ex Vivo Lung Perfusion Annals of Surgery. Mar, 2015 | Pubmed ID: 25371129 The Antiparasitic Drug, Potassium Antimony Tartrate, Inhibits Tumor Angiogenesis and Tumor Growth in Nonsmall-cell Lung Cancer The Journal of Pharmacology and Experimental Therapeutics. Jan, 2015 | Pubmed ID: 25352499 A Novel Synthetic Small Molecule YH-306 Suppresses Colorectal Tumour Growth and Metastasis Via FAK Pathway Journal of Cellular and Molecular Medicine. Feb, 2015 | Pubmed ID: 25351103 Effects of Cucurbitacin E, a Tetracyclic Triterpene Compound from Cucurbitaceae, on the Pharmacokinetics and Pharmacodynamics of Warfarin in Rats Basic & Clinical Pharmacology & Toxicology. May, 2015 | Pubmed ID: 25250504 Claudin 1 Mediates Tumor Necrosis Factor Alpha-induced Cell Migration in Human Gastric Cancer Cells World Journal of Gastroenterology. Dec, 2014 | Pubmed ID: 25548484 Oridonin Inhibits Tumor Growth and Metastasis Through Anti-angiogenesis by Blocking the Notch Signaling PloS One. 2014 | Pubmed ID: 25485753 Evaluation of Enzyme Inhibition Kinetics in Drug-drug Interactions Chemico-biological Interactions. 10, 2014 | Pubmed ID: 25451570 New Functions and Signaling Mechanisms for the Class of Adhesion G Protein-coupled Receptors Annals of the New York Academy of Sciences. Dec, 2014 | Pubmed ID: 25424900 Generation of Site-specific Mutations in the Rat Genome Via CRISPR/Cas9 Methods in Enzymology. 2014 | Pubmed ID: 25398346 De Novo Synthesize of Bile Acids in Pulmonary Arterial Hypertension Lung Metabolomics : Official Journal of the Metabolomic Society. 2014 | Pubmed ID: 25374487 Design and Optimization of Novel Hydroxamate-based Histone Deacetylase Inhibitors of Bis-substituted Aromatic Amides Bearing Potent Activities Against Tumor Growth and Metastasis Journal of Medicinal Chemistry. Nov, 2014 | Pubmed ID: 25360834 Small Molecule 1'-acetoxychavicol Acetate Suppresses Breast Tumor Metastasis by Regulating the SHP-1/STAT3/MMPs Signaling Pathway Breast Cancer Research and Treatment. Nov, 2014 | Pubmed ID: 25301089 XB130 Deficiency Affects Tracheal Epithelial Differentiation During Airway Repair PloS One. 2014 | Pubmed ID: 25272040 Extracellular UDP and P2Y6 Function As a Danger Signal to Protect Mice from Vesicular Stomatitis Virus Infection Through an Increase in IFN-β Production Journal of Immunology (Baltimore, Md. : 1950). Nov, 2014 | Pubmed ID: 25261483 CRISPR/Cas-mediated Genome Editing in the Rat Via Direct Injection of One-cell Embryos Nature Protocols. Oct, 2014 | Pubmed ID: 25255092 Toll-like Receptor-triggered Calcium Mobilization Protects Mice Against Bacterial Infection Through Extracellular ATP Release Infection and Immunity. Dec, 2014 | Pubmed ID: 25245808 Antitumor Action of a Novel Histone Deacetylase Inhibitor, YF479, in Breast Cancer Neoplasia (New York, N.Y.). Aug, 2014 | Pubmed ID: 25220594 GPR126 Protein Regulates Developmental and Pathological Angiogenesis Through Modulation of VEGFR2 Receptor Signaling The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25217645 Total Synthesis and Biological Studies of Cryptocin and Derivatives of Equisetin and Fusarisetin A Organic & Biomolecular Chemistry. Oct, 2014 | Pubmed ID: 25139438 Lgr4 Protein Deficiency Induces Ataxia-like Phenotype in Mice and Impairs Long Term Depression at Cerebellar Parallel Fiber-Purkinje Cell Synapses The Journal of Biological Chemistry. Sep, 2014 | Pubmed ID: 25063812 A Note on CYP2J2-mediated Terfenadine Hydroxylation in Human Liver Microsomes Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Sep, 2014 | Pubmed ID: 24997310 XB130-A Novel Adaptor Protein: Gene, Function, and Roles in Tumorigenesis Scientifica. 2014 | Pubmed ID: 24995146 Measurement Error of Surface-mounted Fiber Bragg Grating Temperature Sensor The Review of Scientific Instruments. Jun, 2014 | Pubmed ID: 24985840 Lgr4 Gene Regulates Corpus Luteum Maturation Through Modulation of the WNT-mediated EGFR-ERK Signaling Pathway Endocrinology. Sep, 2014 | Pubmed ID: 24877628 History and Current Status of Evidence-based Korean Medicine Evidence-based Complementary and Alternative Medicine : ECAM. 2014 | Pubmed ID: 24839452 Structure of the Human P2Y₁₂ Receptor in Complex with an Antithrombotic Drug Science China. Life Sciences. Jun, 2014 | Pubmed ID: 24801571 Optimization of 2-(3-(arylalkyl Amino Carbonyl) Phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone Derivatives As Potent Antitumor Growth and Metastasis Agents European Journal of Medicinal Chemistry. Jun, 2014 | Pubmed ID: 24794770 Low Invasive in Vivo Tissue Sampling for Monitoring Biomarkers and Drugs During Surgery Laboratory Investigation; a Journal of Technical Methods and Pathology. May, 2014 | Pubmed ID: 24687119 Gpr48 Deficiency Induces Polycystic Kidney Lesions and Renal Fibrosis in Mice by Activating Wnt Signal Pathway PloS One. 2014 | Pubmed ID: 24595031 Soluble Platelet-endothelial Cell Adhesion Molecule-1, a Biomarker of Ventilator-induced Lung Injury Critical Care (London, England). Mar, 2014 | Pubmed ID: 24588994 PKA Turnover by the REGγ-proteasome Modulates FoxO1 Cellular Activity and VEGF-induced Angiogenesis Journal of Molecular and Cellular Cardiology. Jul, 2014 | Pubmed ID: 24560667 Metabolomic Heterogeneity of Pulmonary Arterial Hypertension PloS One. 2014 | Pubmed ID: 24533144 LGR4/GPR48 Inactivation Leads to Aniridia-genitourinary Anomalies-mental Retardation Syndrome Defects The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24519938 Protein Kinase C Mediates Enterohemorrhagic Escherichia Coli O157:H7-induced Attaching and Effacing Lesions Infection and Immunity. Apr, 2014 | Pubmed ID: 24491575 Synthesis and Biological Evaluation of Novel Tetrahydro-β-carboline Derivatives As Antitumor Growth and Metastasis Agents Through Inhibiting the Transforming Growth Factor-β Signaling Pathway Journal of Medicinal Chemistry. Feb, 2014 | Pubmed ID: 24417479 Chimeric Anti-IL-17 Full-length Monoclonal Antibody is a Novel Potential Candidate for the Treatment of Rheumatoid Arthritis International Journal of Molecular Medicine. Mar, 2014 | Pubmed ID: 24378614 α1-Antitrypsin Inhibits Ischemia Reperfusion-induced Lung Injury by Reducing Inflammatory Response and Cell Death The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2014 | Pubmed ID: 24365768 Biological Effects of Tat Cell-penetrating Peptide: a Multifunctional Trojan Horse? Nanomedicine (London, England). Jan, 2014 | Pubmed ID: 24354809 LGR4 Acts As a Link Between the Peripheral Circadian Clock and Lipid Metabolism in Liver Journal of Molecular Endocrinology. Apr, 2014 | Pubmed ID: 24353284 Modified in Vivo Lung Perfusion Allows for Prolonged Perfusion Without Acute Lung Injury The Journal of Thoracic and Cardiovascular Surgery. Feb, 2014 | Pubmed ID: 24290703 Inhibitory Effects of Celastrol on Rat Liver Cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 Activity Fitoterapia. Jan, 2014 | Pubmed ID: 24144799 Enhancement of the Pharmacological Efficacy of FGF-21 by Genetic Modification and PEGylation Current Pharmaceutical Biotechnology. 2013 | Pubmed ID: 25106652 Evaluating the Pharmacological Mechanism of Chinese Medicine Si-Wu-Tang Through Multi-level Data Integration PloS One. 2013 | Pubmed ID: 24223693 Solid Phase Microextraction Fills the Gap in Tissue Sampling Protocols Analytica Chimica Acta. Nov, 2013 | Pubmed ID: 24216199 Ablation of LGR4 Promotes Energy Expenditure by Driving White-to-brown Fat Switch Nature Cell Biology. Dec, 2013 | Pubmed ID: 24212090 Efficient Gene Delivery to Pig Airway Epithelia and Submucosal Glands Using Helper-dependent Adenoviral Vectors Molecular Therapy. Nucleic Acids. 2013 | Pubmed ID: 24104599 Zebrafish Cancer and Metastasis Models for in Vivo Drug Discovery Drug Discovery Today. Technologies. 2013 | Pubmed ID: 24050234 GPR116, an Adhesion G-protein-coupled Receptor, Promotes Breast Cancer Metastasis Via the Gαq-p63RhoGEF-Rho GTPase Pathway Cancer Research. Oct, 2013 | Pubmed ID: 24008316 Heritable Gene Targeting in the Mouse and Rat Using a CRISPR-Cas System Nature Biotechnology. Aug, 2013 | Pubmed ID: 23929336 Lgr4 is a Key Regulator of Prostate Development and Prostate Stem Cell Differentiation Stem Cells (Dayton, Ohio). Jul, 2013 | Pubmed ID: 23897697 Lgr4 in Ocular Development and Glaucoma Journal of Ophthalmology. 2013 | Pubmed ID: 23840940 Lgr4 Regulates Mammary Gland Development and Stem Cell Activity Through the Pluripotency Transcription Factor Sox2 Stem Cells (Dayton, Ohio). May, 2013 | Pubmed ID: 23712846 PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells PloS One. 2013 | Pubmed ID: 23691166 High-efficiency and Heritable Gene Targeting in Mouse by Transcription Activator-like Effector Nucleases Nucleic Acids Research. Jun, 2013 | Pubmed ID: 23630316 Lgr4/Gpr48 Negatively Regulates TLR2/4-associated Pattern Recognition and Innate Immunity by Targeting CD14 Expression The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23589304 Lgr4-mediated Wnt/β-catenin Signaling in Peritubular Myoid Cells is Essential for Spermatogenesis Development (Cambridge, England). Apr, 2013 | Pubmed ID: 23533175 XB130, a New Adaptor Protein, Regulates Expression of Tumor Suppressive MicroRNAs in Cancer Cells PloS One. 2013 | Pubmed ID: 23527086 FBW7 Regulates Endothelial Functions by Targeting KLF2 for Ubiquitination and Degradation Cell Research. Jun, 2013 | Pubmed ID: 23507969 Lgr4 Gene Deficiency Increases Susceptibility and Severity of Dextran Sodium Sulfate-induced Inflammatory Bowel Disease in Mice The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23393138 Aqp5 is a New Transcriptional Target of Dot1a and a Regulator of Aqp2 PloS One. 2013 | Pubmed ID: 23326416 Inhibition of Breast Cancer Metastases by a Novel Inhibitor of TGFβ Receptor 1 Journal of the National Cancer Institute. Jan, 2013 | Pubmed ID: 23178439 Atypical Protein Kinase C in Cell Motility Cellular and Molecular Life Sciences : CMLS. Sep, 2013 | Pubmed ID: 23096778 XB130 As an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma Annals of Surgical Oncology. Sep, 2013 | Pubmed ID: 22805860 MEK/ERK Pathway Mediates PKC Activation-induced Recruitment of PKCζ and MMP-9 to Podosomes Journal of Cellular Physiology. Feb, 2013 | Pubmed ID: 22740332 Rejection of Tracheal Allograft by Intrapulmonary Lymphoid Neogenesis in the Absence of Secondary Lymphoid Organs Transplantation. Jun, 2012 | Pubmed ID: 23318304 A Natural Small Molecule Harmine Inhibits Angiogenesis and Suppresses Tumour Growth Through Activation of P53 in Endothelial Cells PloS One. 2012 | Pubmed ID: 23300602 MiR-93 Enhances Angiogenesis and Metastasis by Targeting LATS2 Cell Cycle (Georgetown, Tex.). Dec, 2012 | Pubmed ID: 23111389 Microarray Meta-analysis Identifies Acute Lung Injury Biomarkers in Donor Lungs That Predict Development of Primary Graft Failure in Recipients PloS One. 2012 | Pubmed ID: 23071521 Norcantharidin Facilitates LPS-mediated Immune Responses by Up-regulation of AKT/NF-κB Signaling in Macrophages PloS One. 2012 | Pubmed ID: 22984593 Therapeutic Effects of Inhaling Aerosolized Surfactant Alone or with Dexamethasone Generated by a Novel Noninvasive Apparatus on Acute Lung Injury in Rats The Journal of Trauma and Acute Care Surgery. Nov, 2012 | Pubmed ID: 22976417 Physiologic Assessment of the Ex Vivo Donor Lung for Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Oct, 2012 | Pubmed ID: 22975103 XB130 Mediates Cancer Cell Proliferation and Survival Through Multiple Signaling Events Downstream of Akt PloS One. 2012 | Pubmed ID: 22928011 Cucurbitacin E Inhibits Breast Tumor Metastasis by Suppressing Cell Migration and Invasion Breast Cancer Research and Treatment. Sep, 2012 | Pubmed ID: 22842972 Protective Effects of Long Pentraxin PTX3 on Lung Injury in a Severe Acute Respiratory Syndrome Model in Mice Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2012 | Pubmed ID: 22732935 Knowledge Translation: Airway Epithelial Cell Migration and Respiratory Diseases Cellular and Molecular Life Sciences : CMLS. Dec, 2012 | Pubmed ID: 22718093 KiSS1 and Its G-protein-coupled Receptor GPR54 in Cancer Development and Metastasis Cancer Metastasis Reviews. Dec, 2012 | Pubmed ID: 22692479 Claudin 1 Mediates TNFα-induced Gene Expression and Cell Migration in Human Lung Carcinoma Cells PloS One. 2012 | Pubmed ID: 22675434 Usnic Acid Inhibits Breast Tumor Angiogenesis and Growth by Suppressing VEGFR2-mediated AKT and ERK1/2 Signaling Pathways Angiogenesis. Sep, 2012 | Pubmed ID: 22669534 Molecular Binding of Self-assembling Peptide EAK16-II with Anticancer Agent EPT and Its Implication in Cancer Cell Inhibition Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2012 | Pubmed ID: 22465389 Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post-lung Transplantation in the Pig Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2012 | Pubmed ID: 22453765 Pulmonary Bacterial Communities in Surgically Resected Noncystic Fibrosis Bronchiectasis Lungs Are Similar to Those in Cystic Fibrosis Pulmonary Medicine. 2012 | Pubmed ID: 22448327 Synthesis and Biological Evaluation of Heterocyclic Ring-fused Betulinic Acid Derivatives As Novel Inhibitors of Osteoclast Differentiation and Bone Resorption Journal of Medicinal Chemistry. Apr, 2012 | Pubmed ID: 22435650 Src Tyrosine Kinase Inhibition Prevents Pulmonary Ischemia-reperfusion-induced Acute Lung Injury Intensive Care Medicine. May, 2012 | Pubmed ID: 22349424 Comparative Study of Regulatory T Cells Expanded Ex Vivo from Cord Blood and Adult Peripheral Blood Immunology. Jun, 2012 | Pubmed ID: 22348606 Caffeic Acid 3,4-dihydroxy-phenethyl Ester Suppresses Receptor Activator of NF-κB Ligand–induced Osteoclastogenesis and Prevents Ovariectomy-induced Bone Loss Through Inhibition of Mitogen-activated Protein Kinase/activator Protein 1 and Ca2+–nuclear Factor of Activated T-cells Cytoplasmic 1 Signaling Pathways Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2012 | Pubmed ID: 22337253 Differential Proteomic Analysis of Bronchoalveolar Lavage Fluid from Lung Transplant Patients with and Without Chronic Graft Dysfunction Clinical Biochemistry. Feb, 2012 | Pubmed ID: 22206736 The Actin-binding Domain of Actin Filament-associated Protein (AFAP) is Involved in the Regulation of Cytoskeletal Structure Cellular and Molecular Life Sciences : CMLS. Apr, 2012 | Pubmed ID: 21984596 Self-assembling Peptide-based Nanoparticles Enhance Cellular Delivery of the Hydrophobic Anticancer Drug Ellipticine Through Caveolae-dependent Endocytosis Nanomedicine : Nanotechnology, Biology, and Medicine. Jul, 2012 | Pubmed ID: 21889478 Programming the Cellular Uptake of Physiologically Stable Peptide-gold Nanoparticle Hybrids with Single Amino Acids Angewandte Chemie (International Ed. in English). Oct, 2011 | Pubmed ID: 21948562 Roles of XB130, a Novel Adaptor Protein, in Cancer Journal of Clinical Bioinformatics. Mar, 2011 | Pubmed ID: 21884627 Regression of Allograft Airway Fibrosis: the Role of MMP-dependent Tissue Remodeling in Obliterative Bronchiolitis After Lung Transplantation The American Journal of Pathology. Sep, 2011 | Pubmed ID: 21763265 Local Long-term Expression of Lentivirally Delivered IL-10 in the Lung Attenuates Obliteration of Intrapulmonary Allograft Airways Human Gene Therapy. Nov, 2011 | Pubmed ID: 21568692 Stromal Activation and Formation of Lymphoid-like Stroma in Chronic Lung Allograft Dysfunction Transplantation. Jun, 2011 | Pubmed ID: 21512432 The Potential of Nanoscale Combinations of Self-assembling Peptides and Amino Acids of the Src Tyrosine Kinase Inhibitor in Acute Lung Injury Therapy Biomaterials. Jun, 2011 | Pubmed ID: 21376387 Increased Levels of Interleukin-1β and Tumor Necrosis Factor-α in Donor Lungs Rejected for Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Apr, 2011 | Pubmed ID: 21237675 Actin Filament Associated Protein Mediates C-Src Related SRE/AP-1 Transcriptional Activation FEBS Letters. Feb, 2011 | Pubmed ID: 21236256 XB130, a Novel Adaptor Protein, Promotes Thyroid Tumor Growth The American Journal of Pathology. Jan, 2011 | Pubmed ID: 21224076 Transcriptional Signatures in Donor Lungs from Donation After Cardiac Death Vs After Brain Death: a Functional Pathway Analysis The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2011 | Pubmed ID: 21093300 Long Pentraxin PTX3 Deficiency Worsens LPS-induced Acute Lung Injury Intensive Care Medicine. Feb, 2011 | Pubmed ID: 21072499 Adaptor Protein XB130 is a Rac-controlled Component of Lamellipodia That Regulates Cell Motility and Invasion Journal of Cell Science. Dec, 2010 | Pubmed ID: 21084565 The Protein Kinase C Cascade Regulates Recruitment of Matrix Metalloprotease 9 to Podosomes and Its Release and Activation Molecular and Cellular Biology. Dec, 2010 | Pubmed ID: 20937775 Activating Transcription Factor 3 Confers Protection Against Ventilator-induced Lung Injury American Journal of Respiratory and Critical Care Medicine. Aug, 2010 | Pubmed ID: 20413626 Functions of Type II Pneumocyte-derived Vascular Endothelial Growth Factor in Alveolar Structure, Acute Inflammation, and Vascular Permeability The American Journal of Pathology. Apr, 2010 | Pubmed ID: 20167862 PTX3 As a Potential Biomarker of Acute Lung Injury: Supporting Evidence from Animal Experimentation Intensive Care Medicine. Feb, 2010 | Pubmed ID: 19921147 Functional Repair of Human Donor Lungs by IL-10 Gene Therapy Science Translational Medicine. Oct, 2009 | Pubmed ID: 20368171 Activated Protein C in Ischemia-reperfusion Injury After Experimental Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2009 | Pubmed ID: 19782612 Acute Lung Injury: a Yellow Card for Engineered Nanoparticles? Journal of Molecular Cell Biology. Oct, 2009 | Pubmed ID: 19666688 The Role of Intrapulmonary De Novo Lymphoid Tissue in Obliterative Bronchiolitis After Lung Transplantation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2009 | Pubmed ID: 19454728 Phorbol Ester-induced Podosomes in Normal Human Bronchial Epithelial Cells Journal of Cellular Physiology. Feb, 2009 | Pubmed ID: 18932175 Technique for Prolonged Normothermic Ex Vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Dec, 2008 | Pubmed ID: 19059112 Differential Gene Profiling in Acute Lung Injury Identifies Injury-specific Gene Expression Critical Care Medicine. Mar, 2008 | Pubmed ID: 18431273 Anti-human Tissue Factor Antibody Ameliorated Intestinal Ischemia Reperfusion-induced Acute Lung Injury in Human Tissue Factor Knock-in Mice PloS One. Jan, 2008 | Pubmed ID: 18231608 Acute Lung Injury and Cell Death: How Many Ways Can Cells Die? American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2008 | Pubmed ID: 18203816 The Blimp-1 Gene Regulatory Region Directs EGFP Expression in Multiple Hematopoietic Lineages and Testis in Mice Transgenic Research. Apr, 2008 | Pubmed ID: 17879142 Intestinal Ischemia-reperfusion-induced Acute Lung Injury and Oncotic Cell Death in Multiple Organs Shock (Augusta, Ga.). Aug, 2007 | Pubmed ID: 17666944 Targeted Cell Replacement with Bone Marrow Cells for Airway Epithelial Regeneration American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2007 | Pubmed ID: 17616650 XB130, a Novel Adaptor Protein for Signal Transduction The Journal of Biological Chemistry. Jun, 2007 | Pubmed ID: 17412687 Long Pentraxin 3 in Pulmonary Infection and Acute Lung Injury American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2007 | Pubmed ID: 17277044 Cell-based Tissue Engineering for Lung Regeneration American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2007 | Pubmed ID: 17028264 Toll-like Receptor and Cytokine Gene Expression in the Early Phase of Human Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Nov, 2006 | Pubmed ID: 17097495 The Early Responses of VEGF and Its Receptors During Acute Lung Injury: Implication of VEGF in Alveolar Epithelial Cell Survival Critical Care (London, England). 2006 | Pubmed ID: 16968555 Lipopolysaccharide Accelerates Caspase-independent but Cathepsin B-dependent Death of Human Lung Epithelial Cells Journal of Cellular Physiology. Nov, 2006 | Pubmed ID: 16894574 The Effect of Gender Combinations on Outcome in Human Lung Transplantation: the International Society of Heart and Lung Transplantation Registry Experience The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2006 | Pubmed ID: 16730568 Src Protein Tyrosine Kinase Family and Acute Inflammatory Responses American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2006 | Pubmed ID: 16581827 Activation of Mitogen-activated Protein Kinases During Human Lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Dec, 2005 | Pubmed ID: 16364853 TNFalpha-induced Long Pentraxin PTX3 Expression in Human Lung Epithelial Cells Via JNK Journal of Immunology (Baltimore, Md. : 1950). Dec, 2005 | Pubmed ID: 16339571 Ventilator-induced Lung Injury: Role of Protein-protein Interaction in Mechanosensation Proceedings of the American Thoracic Society. 2005 | Pubmed ID: 16222035 Reperfusion-induced Gene Expression Profiles in Rat Lung Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Sep, 2005 | Pubmed ID: 16095495 PKA Independent and Cell Type Specific Activation of the Expression of Caudal Homeobox Gene Cdx-2 by Cyclic AMP The FEBS Journal. Jun, 2005 | Pubmed ID: 15943809 Innate Immunity and Organ Transplantation: the Potential Role of Toll-like Receptors American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. May, 2005 | Pubmed ID: 15816875 Caspase Inhibition Improves Ischemia-reperfusion Injury After Lung Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Feb, 2005 | Pubmed ID: 15643988 Conversion of Mechanical Force into Biochemical Signaling The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485829 Vascular Endothelial Growth Factor and Related Molecules in Acute Lung Injury Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2004 | Pubmed ID: 15475552 Increased Expression of Nitric Oxide Synthase in Human Lung Transplants After Nitric Oxide Inhalation Transplantation. Mar, 2004 | Pubmed ID: 15077032 Interleukin 10 Gene Transfection of Donor Lungs Ameliorates Posttransplant Cell Death by a Switch from Cellular Necrosis to Apoptosis The Journal of Thoracic and Cardiovascular Surgery. Oct, 2003 | Pubmed ID: 14566265 Impact of Human Interleukin-10 on Vector-induced Inflammation and Early Graft Function in Rat Lung Transplantation American Journal of Respiratory Cell and Molecular Biology. May, 2003 | Pubmed ID: 12707018 Accommodation After Lung Xenografting from Hamster to Rat Transplantation. Mar, 2003 | Pubmed ID: 12640297 Ischemia-reperfusion-induced Lung Injury American Journal of Respiratory and Critical Care Medicine. Feb, 2003 | Pubmed ID: 12588712 Molecular Cloning of Actin Filament-associated Protein: a Putative Adaptor in Stretch-induced Src Activation American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2002 | Pubmed ID: 12114187 Gain Control of N-methyl-D-aspartate Receptor Activity by Receptor-like Protein Tyrosine Phosphatase Alpha The EMBO Journal. Jun, 2002 | Pubmed ID: 12065411 Transplant Immunosuppression Enhances Efficiency of Adenoviral-mediated Gene Retransfection: Inhibition of Interferon-gamma and Immunoglobin G The Annals of Thoracic Surgery. Apr, 2002 | Pubmed ID: 11996247 A Simplified Model for En Bloc Double Lung Xenotransplantation from Hamster to Rat The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Feb, 2002 | Pubmed ID: 11834358 Soluble Transforming Growth Factor-beta Type III Receptor Gene Transfection Inhibits Fibrous Airway Obliteration in a Rat Model of Bronchiolitis Obliterans American Journal of Respiratory and Critical Care Medicine. Feb, 2002 | Pubmed ID: 11818331 Interleukin-8 Release During Early Reperfusion Predicts Graft Function in Human Lung Transplantation American Journal of Respiratory and Critical Care Medicine. Jan, 2002 | Pubmed ID: 11790657 Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation Yamato Suzuki1,2, Stephen Juvet1,2, Mingyao Liu1,2, Shaf Keshavjee1,2 1Latner Thoracic Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Temerty Faculty of Medicine, University of Toronto JoVE 65953 Medicine Protein Kinase C-delta Inhibitor Peptide Formulation using Gold Nanoparticles Hisato Konoeda1, Hong Yang2, Chengliang Yang1, Annette Gower1, Chun Xu1, Wei Zhang1, Mingyao Liu1,3 1Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Respiratory Medicine Research Laboratory, Institute of Translation Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 3Institute of Medical Science, Faculty of Medicine, University of Toronto JoVE 58741 Bioengineering Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid Shaun Pacheco1, Shan-Yu Fung2, Mingyao Liu1,3 1Latner Thoracic Surgery Research Laboratories, University Health Network, 2Department of Pediatrics, British Columbia Children's Hospital & University of British Columbia, 3Institute of Medical Science, University of Toronto JoVE 56158 Medicine
Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation Yamato Suzuki1,2, Stephen Juvet1,2, Mingyao Liu1,2, Shaf Keshavjee1,2 1Latner Thoracic Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Temerty Faculty of Medicine, University of Toronto JoVE 65953 Medicine
Protein Kinase C-delta Inhibitor Peptide Formulation using Gold Nanoparticles Hisato Konoeda1, Hong Yang2, Chengliang Yang1, Annette Gower1, Chun Xu1, Wei Zhang1, Mingyao Liu1,3 1Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Respiratory Medicine Research Laboratory, Institute of Translation Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 3Institute of Medical Science, Faculty of Medicine, University of Toronto JoVE 58741 Bioengineering
Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid Shaun Pacheco1, Shan-Yu Fung2, Mingyao Liu1,3 1Latner Thoracic Surgery Research Laboratories, University Health Network, 2Department of Pediatrics, British Columbia Children's Hospital & University of British Columbia, 3Institute of Medical Science, University of Toronto JoVE 56158 Medicine
