Mohanish Deshmukh Department of Cell and Developmental Biology, Neuroscience Center University of North Carolina Biography Publications Institution JoVE Articles Mohanish Deshmukh has not added a biography. If you are Mohanish Deshmukh and would like to personalize this page please email our Author Liaison for assistance. Publications Rescue from Excitotoxicity and Axonal Degeneration Accompanied by Age-dependent Behavioral and Neuroanatomical Alterations in Caspase-6-deficient Mice Human Molecular Genetics. Jan, 2012 | Pubmed ID: 22262731 MiR-29b is Activated During Neuronal Maturation and Targets BH3-only Genes to Restrict Apoptosis Genes & Development. Jan, 2011 | Pubmed ID: 21245165 Lack of X-linked Inhibitor of Apoptosis Protein Leads to Increased Apoptosis and Tissue Loss Following Neonatal Brain Injury ASN Neuro. 2009 | Pubmed ID: 19570023 Skeletal Muscle Differentiation Evokes Endogenous XIAP to Restrict the Apoptotic Pathway PloS One. 2009 | Pubmed ID: 19333375 Glucose Metabolism Inhibits Apoptosis in Neurons and Cancer Cells by Redox Inactivation of Cytochrome C Nature Cell Biology. Dec, 2008 | Pubmed ID: 19029908 Differential Apaf-1 Levels Allow Cytochrome C to Induce Apoptosis in Brain Tumors but Not in Normal Neural Tissues Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18093951 Chromatin Modification of Apaf-1 Restricts the Apoptotic Pathway in Mature Neurons The Journal of Cell Biology. Dec, 2007 | Pubmed ID: 18056406 Cell Host & Microbe. Sep, 2007 | Pubmed ID: 18005730 Restricting Apoptosis for Postmitotic Cell Survival and Its Relevance to Cancer Cell Cycle (Georgetown, Tex.). Aug, 2006 | Pubmed ID: 16880745 Enhanced Sensitivity to Cytochrome C-induced Apoptosis Mediated by PHAPI in Breast Cancer Cells Cancer Research. Feb, 2006 | Pubmed ID: 16489023 Reduced Apaf-1 Levels in Cardiomyocytes Engage Strict Regulation of Apoptosis by Endogenous XIAP The Journal of Cell Biology. Dec, 2005 | Pubmed ID: 16344307 Bcr-Abl-mediated Protection from Apoptosis Downstream of Mitochondrial Cytochrome C Release Molecular and Cellular Biology. Dec, 2004 | Pubmed ID: 15542838 Decreased Apoptosome Activity with Neuronal Differentiation Sets the Threshold for Strict IAP Regulation of Apoptosis The Journal of Cell Biology. Oct, 2004 | Pubmed ID: 15504912 Stability and Apoptotic Activity of Recombinant Human Cytochrome C Biochemical and Biophysical Research Communications. Dec, 2003 | Pubmed ID: 14680826 Critical Function of Endogenous XIAP in Regulating Caspase Activation During Sympathetic Neuronal Apoptosis The Journal of Cell Biology. Nov, 2003 | Pubmed ID: 14623868 Exogenous Smac Induces Competence and Permits Caspase Activation in Sympathetic Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2002 | Pubmed ID: 12223555 Multiple Channel Interactions Explain the Protection of Sympathetic Neurons from Apoptosis Induced by Nerve Growth Factor Deprivation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756494 Inhibition of the C-Jun N-terminal Kinase Signaling Pathway by the Mixed Lineage Kinase Inhibitor CEP-1347 (KT7515) Preserves Metabolism and Growth of Trophic Factor-deprived Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756493 Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c Adam J. Kole1, Elizabeth R.W. Knight2, Mohanish Deshmukh1 1Department of Cell and Developmental Biology, Neuroscience Center, University of North Carolina, 2Curriculum in Neurobiology, Neuroscience Center, University of North Carolina JoVE 2773 Biology
Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c Adam J. Kole1, Elizabeth R.W. Knight2, Mohanish Deshmukh1 1Department of Cell and Developmental Biology, Neuroscience Center, University of North Carolina, 2Curriculum in Neurobiology, Neuroscience Center, University of North Carolina JoVE 2773 Biology