Monica Driscoll Department of Molecular Biology and Biochemistry Rutgers University Biography Publications Institution JoVE Articles Monica Driscoll has not added a biography. If you are Monica Driscoll and would like to personalize this page please email our Author Liaison for assistance. Publications Gluconeogenesis and PEPCK Are Critical Components of Healthy Aging and Dietary Restriction Life Extension PLoS Genetics. 08, 2020 | Pubmed ID: 32841230 Intervention Testing Program: the Farnesoid X Receptor Agonist Obeticholic Acid Does Not Robustly Extend Lifespan in Nematodes MicroPublication Biology. May, 2020 | Pubmed ID: 32550518 Healthy Lifespan Extension Mediated by Oenothein B Isolated from Eucalyptus Grandis × Eucalyptus Urophylla GL9 in Caenorhabditis Elegans Food & Function. Mar, 2020 | Pubmed ID: 32129349 Intervention Testing Program: the Creatine Analog β-guanidinopropionic Acid Does Not Extend Lifespan in Nematodes MicroPublication Biology. 2020 | Pubmed ID: 31998863 Intervention Testing Program: the Tyrosine Kinase Inhibitor Imatinib Mesylate Does Not Extend Lifespan in Nematodes MicroPublication Biology. 2019 | Pubmed ID: 32010883 Automated Lifespan Determination Across Caenorhabditis Strains and Species Reveals Assay-specific Effects of Chemical Interventions GeroScience. 12, 2019 | Pubmed ID: 31820364 CED-4 CARD Domain Residues Can Modulate Non-apoptotic Neuronal Regeneration Functions Independently from Apoptosis Scientific Reports. 09, 2019 | Pubmed ID: 31527664 NemaFlex: a Microfluidics-based Technology for Standardized Measurement of Muscular Strength of C. Elegans Lab on a Chip. 07, 2018 | Pubmed ID: 29892747 Q&A: Trash Talk: Disposal and Remote Degradation of Neuronal Garbage BMC Biology. 01, 2018 | Pubmed ID: 29382333 TOR-mediated Regulation of Metabolism in Aging Aging Cell. 12, 2017 | Pubmed ID: 28971552 A Long Journey to Reproducible Results Nature. 08, 2017 | Pubmed ID: 28836615 Impact of Genetic Background and Experimental Reproducibility on Identifying Chemical Compounds with Robust Longevity Effects Nature Communications. Feb, 2017 | Pubmed ID: 28220799 Morphological Remodeling of C. Elegans Neurons During Aging is Modified by Compromised Protein Homeostasis NPJ Aging and Mechanisms of Disease. 2016 | Pubmed ID: 27347427 Age-Related Phasic Patterns of Mitochondrial Maintenance in Adult Caenorhabditis Elegans Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2016 | Pubmed ID: 26818523 Using Measures of Single-cell Physiology and Physiological State to Understand Organismic Aging Aging Cell. Feb, 2016 | Pubmed ID: 26616110 A Lysine-rich Motif in the Phosphatidylserine Receptor PSR-1 Mediates Recognition and Removal of Apoptotic Cells Nature Communications. Jan, 2015 | Pubmed ID: 25564762 Flow-scanning Optical Tomography Lab on a Chip. Dec, 2014 | Pubmed ID: 25256716 Insulin Signaling in the Aging of Healthy and Proteotoxically Stressed Mechanosensory Neurons Frontiers in Genetics. 2014 | Pubmed ID: 25101108 CeleST: Computer Vision Software for Quantitative Analysis of C. Elegans Swim Behavior Reveals Novel Features of Locomotion PLoS Computational Biology. Jul, 2014 | Pubmed ID: 25033081 Mechanism of Longevity Extension of Caenorhabditis Elegans Induced by Pentagalloyl Glucose Isolated from Eucalyptus Leaves Journal of Agricultural and Food Chemistry. Apr, 2014 | Pubmed ID: 24701969 A Novel MitoTimer Reporter Gene for Mitochondrial Content, Structure, Stress, and Damage in Vivo The Journal of Biological Chemistry. Apr, 2014 | Pubmed ID: 24644293 NRA-2, a Nicalin Homolog, Regulates Neuronal Death by Controlling Surface Localization of Toxic Caenorhabditis Elegans DEG/ENaC Channels The Journal of Biological Chemistry. Apr, 2014 | Pubmed ID: 24567339 Neuronal Repair: Apoptotic Proteins Make Good Worm. Apr, 2013 | Pubmed ID: 24058867 Deletion of MicroRNA-80 Activates Dietary Restriction to Extend C. Elegans Healthspan and Lifespan PLoS Genetics. Aug, 2013 | Pubmed ID: 24009527 Dramatic Fertility Decline in Aging C. Elegans Males is Associated with Mating Execution Deficits Rather Than Diminished Sperm Quality Experimental Gerontology. Nov, 2013 | Pubmed ID: 23916839 Complex Expression Dynamics and Robustness in C. Elegans Insulin Networks Genome Research. Jun, 2013 | Pubmed ID: 23539137 Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis Elegans Nervous System The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2012 | Pubmed ID: 22745480 The Core Apoptotic Executioner Proteins CED-3 and CED-4 Promote Initiation of Neuronal Regeneration in Caenorhabditis Elegans PLoS Biology. 2012 | Pubmed ID: 22629231 EGF Signaling Comes of Age: Promotion of Healthy Aging in C. Elegans Experimental Gerontology. Feb-Mar, 2011 | Pubmed ID: 21074601 Spatial Asymmetry in the Mechanosensory Phenotypes of the C. Elegans DEG/ENaC Gene Mec-10 Journal of Neurophysiology. Dec, 2010 | Pubmed ID: 20881202 Specific Roles for DEG/ENaC and TRP Channels in Touch and Thermosensation in C. Elegans Nociceptors Nature Neuroscience. Jul, 2010 | Pubmed ID: 20512132 Novel EGF Pathway Regulators Modulate C. Elegans Healthspan and Lifespan Via EGF Receptor, PLC-gamma, and IP3R Activation Aging Cell. Aug, 2010 | Pubmed ID: 20497132 Metformin Induces a Dietary Restriction-like State and the Oxidative Stress Response to Extend C. Elegans Healthspan Via AMPK, LKB1, and SKN-1 PloS One. Jan, 2010 | Pubmed ID: 20090912 MicroRNAs in C. Elegans Aging: Molecular Insurance for Robustness? Current Genomics. May, 2009 | Pubmed ID: 19881908 FOXO3a is Broadly Neuroprotective in Vitro and in Vivo Against Insults Implicated in Motor Neuron Diseases The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2009 | Pubmed ID: 19553463 Caenorhabditis Elegans Glutamate Transporter Deletion Induces AMPA-receptor/adenylyl Cyclase 9-dependent Excitotoxicity Journal of Neurochemistry. Mar, 2009 | Pubmed ID: 19054279 A Glial DEG/ENaC Channel Functions with Neuronal Channel DEG-1 to Mediate Specific Sensory Functions in C. Elegans The EMBO Journal. Sep, 2008 | Pubmed ID: 18701922 Sequence Relationships Among C. Elegans, D. Melanogaster and Human MicroRNAs Highlight the Extensive Conservation of MicroRNAs in Biology PloS One. Jul, 2008 | Pubmed ID: 18665242 A Novel Computational Approach for Simultaneous Tracking and Feature Extraction of C. Elegans Populations in Fluid Environments IEEE Transactions on Bio-medical Engineering. May, 2008 | Pubmed ID: 18440900 A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. Elegans PLoS Genetics. Feb, 2008 | Pubmed ID: 18282106 Caenorhabditis Elegans Glutamate Transporters Influence Synaptic Function and Behavior at Sites Distant from the Synapse The Journal of Biological Chemistry. Nov, 2007 | Pubmed ID: 17681948 Heterologous Expression of C. Elegans Ion Channels in Xenopus Oocytes WormBook : the Online Review of C. Elegans Biology. 2006 | Pubmed ID: 18050441 Culture of Embryonic C. Elegans Cells for Electrophysiological and Pharmacological Analyses WormBook : the Online Review of C. Elegans Biology. 2006 | Pubmed ID: 18050435 Modulated MicroRNA Expression During Adult Lifespan in Caenorhabditis Elegans Aging Cell. Jun, 2006 | Pubmed ID: 16842496 Temperature-sensitive Mutant of the Caenorhabditis Elegans Neurotoxic MEC-4(d) DEG/ENaC Channel Identifies a Site Required for Trafficking or Surface Maintenance The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16239217 In Vivo Spectrofluorimetry Reveals Endogenous Biomarkers That Report Healthspan and Dietary Restriction in Caenorhabditis Elegans Aging Cell. Jun, 2005 | Pubmed ID: 15924569 The Neurotoxic MEC-4(d) DEG/ENaC Sodium Channel Conducts Calcium: Implications for Necrosis Initiation Nature Neuroscience. Dec, 2004 | Pubmed ID: 15543143 In Vivo Imaging of C. Elegans Mechanosensory Neurons Demonstrates a Specific Role for the MEC-4 Channel in the Process of Gentle Touch Sensation Neuron. Sep, 2003 | Pubmed ID: 12971899 Modeling Human Peroxisome Biogenesis Disorders in the Nematode Caenorhabditis Elegans Journal of Cell Science. May, 2003 | Pubmed ID: 12665560 Dying for a Cause: Invertebrate Genetics Takes on Human Neurodegeneration Nature Reviews. Genetics. Mar, 2003 | Pubmed ID: 12610523 A Potassium Channel-MiRP Complex Controls Neurosensory Function in Caenorhabditis Elegans The Journal of Biological Chemistry. Apr, 2003 | Pubmed ID: 12533541 Specific Aspartyl and Calpain Proteases Are Required for Neurodegeneration in C. Elegans Nature. Oct, 2002 | Pubmed ID: 12410314 Stochastic and Genetic Factors Influence Tissue-specific Decline in Ageing C. Elegans Nature. Oct, 2002 | Pubmed ID: 12397350 Protons at the Gate: DEG/ENaC Ion Channels Help Us Feel and Remember Neuron. Apr, 2002 | Pubmed ID: 11988165 Caloric Restriction and Lifespan: a Role for Protein Turnover? Mechanisms of Ageing and Development. Jan, 2002 | Pubmed ID: 11718814 Execution of Necrotic-Like Cell Death in Requires Cathepsin D Activity TheScientificWorldJournal. 2001 | Pubmed ID: 30147617 Necrotic Neurodegeneration in Caenorhabditis Elegans TheScientificWorldJournal. 2001 | Pubmed ID: 30147608 UNC-4/UNC-37-dependent Repression of Motor Neuron-specific Genes Controls Synaptic Choice in Caenorhabditis Elegans Genes & Development. Nov, 1999 | Pubmed ID: 10557206 Neuropathology of Degenerative Cell Death in Caenorhabditis Elegans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 1997 | Pubmed ID: 8994058 Kvantitative tilnærminger for scoring in vivo Neuronal Aggregate og Organelle Extrusion i Store Exopher Vesicles i C. elegans Meghan Lee Arnold*1, Jason Cooper*1, Barth D. Grant1, Monica Driscoll1 1Department of Molecular Biology and Biochemistry, Rutgers University JoVE 61368 Neuroscience Automatisert analyse av Carolina Ibáñez-Ventoso1, Christopher Herrera2, Esteban Chen1, Douglas Motto2, Monica Driscoll1 1Department of Molecular Biology and Biochemistry, Rutgers University, 2Computing Research and Education Building (CoRE), Rutgers University JoVE 54359 Neuroscience
Kvantitative tilnærminger for scoring in vivo Neuronal Aggregate og Organelle Extrusion i Store Exopher Vesicles i C. elegans Meghan Lee Arnold*1, Jason Cooper*1, Barth D. Grant1, Monica Driscoll1 1Department of Molecular Biology and Biochemistry, Rutgers University JoVE 61368 Neuroscience
Automatisert analyse av Carolina Ibáñez-Ventoso1, Christopher Herrera2, Esteban Chen1, Douglas Motto2, Monica Driscoll1 1Department of Molecular Biology and Biochemistry, Rutgers University, 2Computing Research and Education Building (CoRE), Rutgers University JoVE 54359 Neuroscience
