Morgan Huse

Publications

• Mechanical Forces in the Immune System
  Nature Reviews. Immunology. Nov, 2017  |   Pubmed ID: 28757604
• Sorting Nexin 27 Interactome in T-lymphocytes Identifies Zona Occludens-2 Dynamic Redistribution at the Immune Synapse
  Traffic (Copenhagen, Denmark). 08, 2017  |   Pubmed ID: 28477369
• A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System
  Immunity. 04, 2017  |   Pubmed ID: 28389069
• Probing Synaptic Biomechanics Using Micropillar Arrays
  Methods in Molecular Biology (Clifton, N.J.). 2017  |   Pubmed ID: 28255710
• Mechanical Communication at the Immunological Synapse
  Trends in Cell Biology. 04, 2017  |   Pubmed ID: 27986534
• Successful Engineering of a Highly Potent Single-chain Variable-fragment (scFv) Bispecific Antibody to Target Disialoganglioside (GD2) Positive Tumors
  Oncoimmunology. Jun, 2016  |   Pubmed ID: 27471647
• Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
  Cell. Mar, 2016  |   Pubmed ID: 26924577
• Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells
  Cell. Jan, 2016  |   Pubmed ID: 26806130
• A Generalizable Platform for the Photoactivation of Cell Surface Receptors
  ACS Chemical Biology. Nov, 2015  |   Pubmed ID: 26295186
• Retargeting T Cells to GD2 Pentasaccharide on Human Tumors Using Bispecific Humanized Antibody
  Cancer Immunology Research. Mar, 2015  |   Pubmed ID: 25542634
• Molecular Mechanisms and Functional Implications of Polarized Actin Remodeling at the T Cell Immunological Synapse
  Cellular and Molecular Life Sciences : CMLS. Feb, 2015  |   Pubmed ID: 25355055
• Lipid-based Patterning of the Immunological Synapse
  Biochemical Society Transactions. Dec, 2014  |   Pubmed ID: 25399561
• Diacylglycerol Kinase α Establishes T Cell Polarity by Shaping Diacylglycerol Accumulation at the Immunological Synapse
  Science Signaling. Aug, 2014  |   Pubmed ID: 25161317
• The Variable Hinge Region of Novel PKCs Determines Localization to Distinct Regions of the Immunological Synapse
  PloS One. 2014  |   Pubmed ID: 24751783
• CD28 and CD3 Have Complementary Roles in T-cell Traction Forces
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014  |   Pubmed ID: 24469820
• Inhibitory Receptor Signaling Destabilizes Immunological Synapse Formation in Primary NK Cells
  Frontiers in Immunology. 2013  |   Pubmed ID: 24348477
• Annular PIP3 Accumulation Controls Actin Architecture and Modulates Cytotoxicity at the Immunological Synapse
  The Journal of Experimental Medicine. Nov, 2013  |   Pubmed ID: 24190432
• From Lipid Second Messengers to Molecular Motors: Microtubule-organizing Center Reorientation in T Cells
  Immunological Reviews. Nov, 2013  |   Pubmed ID: 24117815
• Diacylglycerol Promotes Centrosome Polarization in T Cells Via Reciprocal Localization of Dynein and Myosin II
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013  |   Pubmed ID: 23818610
• IL-2-dependent Tuning of NK Cell Sensitivity for Target Cells is Controlled by Regulatory T Cells
  The Journal of Experimental Medicine. Jun, 2013  |   Pubmed ID: 23650441
• NK Cell Tolerance of Self-specific Activating Receptor KIR2DS1 in Individuals with Cognate HLA-C2 Ligand
  Journal of Immunology (Baltimore, Md. : 1950). May, 2013  |   Pubmed ID: 23554313
• Building Tolerance by Dismantling Synapses: Inhibitory Receptor Signaling in Natural Killer Cells
  Immunological Reviews. Jan, 2013  |   Pubmed ID: 23278746
• Novel Foxo1-dependent Transcriptional Programs Control T(reg) Cell Function
  Nature. Nov, 2012  |   Pubmed ID: 23135404
• Protein Kinase C-θ Clustering at Immunological Synapses Amplifies Effector Responses in NK Cells
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2012  |   Pubmed ID: 23077238
• Microtubule-organizing Center Polarity and the Immunological Synapse: Protein Kinase C and Beyond
  Frontiers in Immunology. 2012  |   Pubmed ID: 23060874
• Lymphocyte Polarity, the Immunological Synapse and the Scope of Biological Analogy
  Bioarchitecture. Jul, 2011  |   Pubmed ID: 22069511
• A Cascade of Protein Kinase C Isozymes Promotes Cytoskeletal Polarization in T Cells
  Nature Immunology. May, 2011  |   Pubmed ID: 21602810
• Inhibitory Signaling Blocks Activating Receptor Clustering and Induces Cytoskeletal Retraction in Natural Killer Cells
  The Journal of Cell Biology. Feb, 2011  |   Pubmed ID: 21339333
• Photochemical Approaches to T-cell Activation
  Immunology. Jun, 2010  |   Pubmed ID: 20406301
• Localized Diacylglycerol Drives the Polarization of the Microtubule-organizing Center in T Cells
  Nature Immunology. Jun, 2009  |   Pubmed ID: 19430478
• The T-cell-receptor Signaling Network
  Journal of Cell Science. May, 2009  |   Pubmed ID: 19386893
• Shouts, Whispers and the Kiss of Death: Directional Secretion in T Cells
  Nature Immunology. Oct, 2008  |   Pubmed ID: 18800163