Moses V. Chao Molecular Neurobiology Program, Skirball Institute for Biomolecular Medicine New York University School of Medicine Biography Publications Institution JoVE Articles Moses V. Chao has not added a biography. If you are Moses V. Chao and would like to personalize this page please email our Author Liaison for assistance. Publications The BDNF Val66Met Polymorphism Impairs Synaptic Transmission and Plasticity in the Infralimbic Medial Prefrontal Cortex The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2012 | Pubmed ID: 22396415 Transient Reversal of Episome Silencing Precedes VP16-Dependent Transcription During Reactivation of Latent HSV-1 in Neurons PLoS Pathogens. Feb, 2012 | Pubmed ID: 22383875 Reversal of Impaired Hippocampal Long-Term Potentiation and Contextual Fear Memory Deficits in Angelman Syndrome Model Mice by ErbB Inhibitors Biological Psychiatry. Feb, 2012 | Pubmed ID: 22381732 BDNF and Glucocorticoids Regulate Corticotrophin-releasing Hormone (CRH) Homeostasis in the Hypothalamus Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22232675 BDNF Val66Met Impairs Fluoxetine-Induced Enhancement of Adult Hippocampus Plasticity Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2012 | Pubmed ID: 22218094 A Cell Culture Model of Facial Palsy Resulting from Reactivation of Latent Herpes Simplex Type 1 Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. Jan, 2012 | Pubmed ID: 22158020 Huntingtin Mediates Dendritic Transport of β-actin MRNA in Rat Neurons Scientific Reports. 2011 | Pubmed ID: 22355657 Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac Science Signaling. 2011 | Pubmed ID: 22155786 Spatial Segregation of BDNF Transcripts Enables BDNF to Differentially Shape Distinct Dendritic Compartments Proceedings of the National Academy of Sciences of the United States of America. Oct, 2011 | Pubmed ID: 21933955 Identifying Transient Protein-protein Interactions in EphB2 Signaling by Blue Native PAGE and Mass Spectrometry Proteomics. Dec, 2011 | Pubmed ID: 21932443 Cultured Vestibular Ganglion Neurons Demonstrate Latent HSV1 Reactivation The Laryngoscope. Oct, 2011 | Pubmed ID: 21898423 TrkB As a Potential Synaptic and Behavioral Tag The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2011 | Pubmed ID: 21849537 APP is Phosphorylated by TrkA and Regulates NGF/TrkA Signaling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2011 | Pubmed ID: 21849536 Paranodal Permeability in "myelin Mutants" Glia. Oct, 2011 | Pubmed ID: 21618613 Distribution of Phosphorylated TrkB Receptor in the Mouse Hippocampal Formation Depends on Sex and Estrous Cycle Stage The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2011 | Pubmed ID: 21543608 A Selective Role for ARMS/Kidins220 Scaffold Protein in Spatial Memory and Trophic Support of Entorhinal and Frontal Cortical Neurons Experimental Neurology. Jun, 2011 | Pubmed ID: 21419124 Study of Neurotrophin-3 Signaling in Primary Cultured Neurons Using Multiplex Stable Isotope Labeling with Amino Acids in Cell Culture Journal of Proteome Research. May, 2011 | Pubmed ID: 21370927 Regulation of Trafficking of Activated TrkA is Critical for NGF-mediated Functions Traffic (Copenhagen, Denmark). Apr, 2011 | Pubmed ID: 21199218 Sortilin Associates with Trk Receptors to Enhance Anterograde Transport and Neurotrophin Signaling Nature Neuroscience. Jan, 2011 | Pubmed ID: 21102451 Nature and Duration of Growth Factor Signaling Through Receptor Tyrosine Kinases Regulates HSV-1 Latency in Neurons Cell Host & Microbe. Oct, 2010 | Pubmed ID: 20951966 The Ankyrin Repeat-rich Membrane Spanning (ARMS)/Kidins220 Scaffold Protein is Regulated by Activity-dependent Calpain Proteolysis and Modulates Synaptic Plasticity The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20943655 Regulation of Inhibitory Neurotransmission by the Scaffolding Protein Ankyrin Repeat-rich Membrane Spanning/kinase D-interacting Substrate of 220 KDa Journal of Neuroscience Research. Dec, 2010 | Pubmed ID: 20936698 The MAP Kinase Phosphatase MKP-1 Regulates BDNF-induced Axon Branching Nature Neuroscience. Nov, 2010 | Pubmed ID: 20935641 Ankyrin Repeat-rich Membrane Spanning/Kidins220 Protein Interacts with Mammalian Septin 5 Molecules and Cells. Aug, 2010 | Pubmed ID: 20680483 SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity Through Deacetylation of Specific Lysine Residues in Mammals PloS One. 2010 | Pubmed ID: 20668706 Increasing the Specificity of Neurotrophic Factors Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20656936 Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression Biological Psychiatry. Nov, 2010 | Pubmed ID: 20655510 Transactivation of Trk Receptors in Spinal Motor Neurons Histology and Histopathology. Sep, 2010 | Pubmed ID: 20607662 The BDNF Val66Met Polymorphism Impairs NMDA Receptor-dependent Synaptic Plasticity in the Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20592208 Activation of Adenosine A2A Receptors Induces TrkB Translocation and Increases BDNF-mediated Phospho-TrkB Localization in Lipid Rafts: Implications for Neuromodulation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010 | Pubmed ID: 20573894 The ARMS/Kidins220 Scaffold Protein Modulates Synaptic Transmission Molecular and Cellular Neurosciences. Oct, 2010 | Pubmed ID: 20547223 Localization of BDNF MRNA with the Huntington's Disease Protein in Rat Brain Molecular Neurodegeneration. 2010 | Pubmed ID: 20507609 Role of Transverse Bands in Maintaining Paranodal Structure and Axolemmal Domain Organization in Myelinated Nerve Fibers: Effect on Longevity in Dysmyelinated Mutant Mice The Journal of Comparative Neurology. Jul, 2010 | Pubmed ID: 20506478 Organophosphates Induce Distal Axonal Damage, but Not Brain Oedema, by Inactivating Neuropathy Target Esterase Toxicology and Applied Pharmacology. May, 2010 | Pubmed ID: 20188121 Trophic Factors: 50 Years of Growth Developmental Neurobiology. Apr, 2010 | Pubmed ID: 20186706 A Role for Huntington Disease Protein in Dendritic RNA Granules The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20185826 Trk Activation in the Secretory Pathway Promotes Golgi Fragmentation Molecular and Cellular Neurosciences. Apr, 2010 | Pubmed ID: 20123019 Nuclear Localization of the P75 Neurotrophin Receptor Intracellular Domain The Journal of Biological Chemistry. Feb, 2010 | Pubmed ID: 20022966 A Conversation with Rita Levi-Montalcini Annual Review of Physiology. 2010 | Pubmed ID: 19827948 Proneurotrophin-3 is a Neuronal Apoptotic Ligand: Evidence for Retrograde-directed Cell Killing The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19940174 Neuropathy Target Esterase is Required for Adult Vertebrate Axon Maintenance The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2009 | Pubmed ID: 19759306 Spongiform Pathology in Mouse CNS Lacking 'neuropathy Target Esterase' and Cellular Prion Protein Neurobiology of Disease. Sep, 2009 | Pubmed ID: 19524041 Ankyrin Repeat-rich Membrane Spanning/Kidins220 Protein Regulates Dendritic Branching and Spine Stability in Vivo Developmental Neurobiology. Aug, 2009 | Pubmed ID: 19449316 Essential Role of Hrs in Endocytic Recycling of Full-length TrkB Receptor but Not Its Isoform TrkB.T1 The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19351881 Neuroprotective Effects of Brain-derived Neurotrophic Factor in Rodent and Primate Models of Alzheimer's Disease Nature Medicine. Mar, 2009 | Pubmed ID: 19198615 Ankyrin-rich Membrane Spanning Protein Plays a Critical Role in Nuclear Factor-kappa B Signaling Molecular and Cellular Neurosciences. Jul, 2008 | Pubmed ID: 18501627 Dopamine D1 Receptor-induced Signaling Through TrkB Receptors in Striatal Neurons The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18381284 Activation of Trk Neurotrophin Receptors by Glucocorticoids Provides a Neuroprotective Effect Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18347336 Variant Brain-derived Neurotrophic Factor (Val66Met) Alters Adult Olfactory Bulb Neurogenesis and Spontaneous Olfactory Discrimination The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2008 | Pubmed ID: 18322085 Stable Isotopic Labeling by Amino Acids in Cultured Primary Neurons: Application to Brain-derived Neurotrophic Factor-dependent Phosphotyrosine-associated Signaling Molecular & Cellular Proteomics : MCP. Jun, 2008 | Pubmed ID: 18256212 Adenosine Receptor A2A-R Contributes to Motoneuron Survival by Transactivating the Tyrosine Kinase Receptor TrkB Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17940030 Developmental and Activity-dependent Regulation of ARMS/Kidins220 in Cultured Rat Hippocampal Neurons Developmental Neurobiology. Nov, 2007 | Pubmed ID: 17587220 P75 Neurotrophin Receptor Regulates Tissue Fibrosis Through Inhibition of Plasminogen Activation Via a PDE4/cAMP/PKA Pathway The Journal of Cell Biology. Jun, 2007 | Pubmed ID: 17576803 The Tyrosine Kinase Fyn Determines the Localization of TrkB Receptors in Lipid Rafts The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17475794 Neurotrophins, Synaptic Plasticity and Dementia Current Opinion in Neurobiology. Jun, 2007 | Pubmed ID: 17419049 Pharmacologically Diverse Antidepressants Rapidly Activate Brain-derived Neurotrophic Factor Receptor TrkB and Induce Phospholipase-Cgamma Signaling Pathways in Mouse Brain Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Oct, 2007 | Pubmed ID: 17314919 TrkA Receptor Activation by Nerve Growth Factor Induces Shedding of the P75 Neurotrophin Receptor Followed by Endosomal Gamma-secretase-mediated Release of the P75 Intracellular Domain The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17215246 Pro-NGF Secreted by Astrocytes Promotes Motor Neuron Cell Death Molecular and Cellular Neurosciences. Feb, 2007 | Pubmed ID: 17188890 Ira B. Black 1941-2006 Neuron. Mar, 2006 | Pubmed ID: 20461897 A Role for Fyn in Trk Receptor Transactivation by G-protein-coupled Receptor Signaling Molecular and Cellular Neurosciences. Sep, 2006 | Pubmed ID: 16860569 BDNF-mediated Neurotransmission Relies Upon a Myosin VI Motor Complex Nature Neuroscience. Aug, 2006 | Pubmed ID: 16819522 Promoting Neurotrophic Effects by GPCR Ligands Novartis Foundation Symposium. 2006 | Pubmed ID: 16805430 Cell Survival Through Trk Neurotrophin Receptors is Differentially Regulated by Ubiquitination Neuron. May, 2006 | Pubmed ID: 16701206 Ligand-dependent Cleavage of the P75 Neurotrophin Receptor is Necessary for NRIF Nuclear Translocation and Apoptosis in Sympathetic Neurons Neuron. Apr, 2006 | Pubmed ID: 16630834 Neurotrophin Signalling in Health and Disease Clinical Science (London, England : 1979). Feb, 2006 | Pubmed ID: 16411893 Identification of a Switch in Neurotrophin Signaling by Selective Tyrosine Phosphorylation The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16284401 Biochemical Characterization of Intracellular Membranes Bearing Trk Neurotrophin Receptors Neurochemical Research. Jun-Jul, 2005 | Pubmed ID: 16187212 Neuregulin-1 Type III Determines the Ensheathment Fate of Axons Neuron. Sep, 2005 | Pubmed ID: 16129398 MAG Induces Regulated Intramembrane Proteolysis of the P75 Neurotrophin Receptor to Inhibit Neurite Outgrowth Neuron. Jun, 2005 | Pubmed ID: 15953414 {alpha}-Syntrophin Regulates ARMS Localization at the Neuromuscular Junction and Enhances EphA4 Signaling in an ARMS-dependent Manner The Journal of Cell Biology. Jun, 2005 | Pubmed ID: 15939763 Axonal Growth: Where Neurotrophins Meet Wnts Current Opinion in Cell Biology. Apr, 2005 | Pubmed ID: 15780585 Cleavage of P75 Neurotrophin Receptor by Alpha-secretase and Gamma-secretase Requires Specific Receptor Domains The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15701642 Neurotrophin Survival Signaling Mechanisms Journal of Alzheimer's Disease : JAD. Dec, 2004 | Pubmed ID: 15665417 Ternary Complex with Trk, P75, and an Ankyrin-rich Membrane Spanning Protein Journal of Neuroscience Research. Oct, 2004 | Pubmed ID: 15378608 Transactivation of Trk Neurotrophin Receptors by G-protein-coupled Receptor Ligands Occurs on Intracellular Membranes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004 | Pubmed ID: 15282267 A Unique Pathway for Sustained Neurotrophin Signaling Through an Ankyrin-rich Membrane-spanning Protein The EMBO Journal. Jun, 2004 | Pubmed ID: 15167895 Structural Biology. The P75 NGF Receptor Exposed Science (New York, N.Y.). May, 2004 | Pubmed ID: 15131296 Brain-specific Deletion of Neuropathy Target Esterase/swisscheese Results in Neurodegeneration Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004 | Pubmed ID: 15051870 The P75NTR-interacting Protein SC1 Inhibits Cell Cycle Progression by Transcriptional Repression of Cyclin E The Journal of Cell Biology. Mar, 2004 | Pubmed ID: 15051733 A Novel P75 Neurotrophin Receptor-related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15028767 Prevention of Apoptotic but Not Necrotic Cell Death Following Neuronal Injury by Neurotrophins Signaling Through the Tyrosine Kinase Receptor Journal of Neurosurgery. Jan, 2004 | Pubmed ID: 14743916 Mechanisms of Neurotrophin Receptor Vesicular Transport Journal of Neurobiology. Feb, 2004 | Pubmed ID: 14704956 Motors, Adaptors, and Receptors: Key Elements of Neuronal Transport Journal of Neurobiology. Feb, 2004 | Pubmed ID: 14704948 Dependence Receptors: What is the Mechanism? Science's STKE : Signal Transduction Knowledge Environment. Sep, 2003 | Pubmed ID: 13130129 Telomerase Activity in the Subventricular Zone of Adult Mice Molecular and Cellular Neurosciences. Aug, 2003 | Pubmed ID: 12932448 Regulated Intramembrane Proteolysis of the P75 Neurotrophin Receptor Modulates Its Association with the TrkA Receptor The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12913006 Retrograde Transport Redux Neuron. Jul, 2003 | Pubmed ID: 12848924 JNK-interacting Protein 1 Promotes Akt1 Activation The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12783873 Neurotrophins and Their Receptors: a Convergence Point for Many Signalling Pathways Nature Reviews. Neuroscience. Apr, 2003 | Pubmed ID: 12671646 Akt1 Regulates a JNK Scaffold During Excitotoxic Apoptosis Neuron. Aug, 2002 | Pubmed ID: 12194869 Annexin II Light Chain Regulates Sensory Neuron-specific Sodium Channel Expression Nature. Jun, 2002 | Pubmed ID: 12050667 Lack of the Cell-cycle Inhibitor P27Kip1 Results in Selective Increase of Transit-amplifying Cells for Adult Neurogenesis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2002 | Pubmed ID: 11896165 Activation of Trk Neurotrophin Receptor Signaling by Pituitary Adenylate Cyclase-activating Polypeptides The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11784714 Neurotrophins: to Cleave or Not to Cleave Neuron. Jan, 2002 | Pubmed ID: 11779474 Distinctive Features of Trk Neurotrophin Receptor Transactivation by G Protein-coupled Receptors Cytokine & Growth Factor Reviews. Feb, 2002 | Pubmed ID: 11750876 A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation Mariko Kobayashi1, Ju-Youn Kim1, Vladimir Camarena2, Pamela C. Roehm3, Moses V. Chao2,4,5,6,7, Angus C. Wilson1, Ian Mohr1 1Department of Microbiology, New York University School of Medicine, 2Molecular Neurobiology Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, 3Department of Otolaryngology, New York University School of Medicine, 4Department of Cell Biology, New York University School of Medicine, 5Department of Physiology and Neuroscience, New York University School of Medicine, 6Department of Psychiatry, New York University School of Medicine, 7Center for Neural Science, New York University School of Medicine JoVE 3823 Immunology and Infection
A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation Mariko Kobayashi1, Ju-Youn Kim1, Vladimir Camarena2, Pamela C. Roehm3, Moses V. Chao2,4,5,6,7, Angus C. Wilson1, Ian Mohr1 1Department of Microbiology, New York University School of Medicine, 2Molecular Neurobiology Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, 3Department of Otolaryngology, New York University School of Medicine, 4Department of Cell Biology, New York University School of Medicine, 5Department of Physiology and Neuroscience, New York University School of Medicine, 6Department of Psychiatry, New York University School of Medicine, 7Center for Neural Science, New York University School of Medicine JoVE 3823 Immunology and Infection
