Other Publications (1)
Articles by Muhammad Ajmal Ayub in JoVE
A Closed-chest Model to Induce Transverse Aortic Constriction in Mice Lars Eichhorn*1, Christina Katharina Weisheit*1, Christopher Gestrich2, Konrad Peukert1, Georg Daniel Duerr2, Muhammad Ajmal Ayub3, Felix Erdfelder1, Florian Stöckigt4 1Department of Anaesthesiology, University Hospital Bonn, 2Department of Cardiac Surgery, University Hospital Bonn, 3Institute of Physiology 2, University of Bonn, 4Department of Medicine - Cardiology, University Hospital Bonn Here, we present a protocol of Transverse Aortic constriction (TAC) via a lateral thoracotomy. This technique is a minimally invasive, closed chest surgical procedure aiming to simulate pressure overload and heart failure in mice utilizing standard TAC laboratory settings.
Other articles by Muhammad Ajmal Ayub on PubMed
Sustained Apnea Induces Endothelial Activation Clinical Cardiology. | Pubmed ID: 28464406 Apnea diving has gained worldwide popularity, even though the pathophysiological consequences of this challenging sport on the human body are poorly investigated and understood. This study aims to assess the influence of sustained apnea in healthy volunteers on circulating microparticles (MPs) and microRNAs (miRs), which are established biomarkers reflecting vascular function.