N. Joan Abbott

Publications

• The Blood-brain Barrier in Psychosis
  The Lancet. Psychiatry. Aug, 2017  |   Pubmed ID: 28781208
• Uptake and Metabolism of Sulphated Steroids by the Blood-brain Barrier in the Adult Male Rat
  Journal of Neurochemistry. Sep, 2017  |   Pubmed ID: 28665486
• Impact of Capillary Flow Hydrodynamics on Carrier-mediated Transport of Opioid Derivatives at the Blood-brain Barrier, Based on PH-dependent Michaelis-Menten and Crone-Renkin Analyses
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Aug, 2017  |   Pubmed ID: 28614733
• Bidirectional Apical-basal Traffic of the Cation-independent Mannose-6-phosphate Receptor in Brain Endothelial Cells
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2017  |   Pubmed ID: 28337939
• In vitro Models of the Blood-brain Barrier: An Overview of Commonly Used Brain Endothelial Cell Culture Models and Guidelines for Their Use
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2016  |   Pubmed ID: 26868179
• Translocation of LRP1 Targeted Carbon Nanotubes of Different Diameters Across the Blood-brain Barrier in Vitro and in Vivo
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Mar, 2016  |   Pubmed ID: 26809004
• LRP-1-mediated Intracellular Antibody Delivery to the Central Nervous System
  Scientific Reports. Jul, 2015  |   Pubmed ID: 26189707
• The Interaction of Carbon Nanotubes with an in Vitro Blood-brain Barrier Model and Mouse Brain in Vivo
  Biomaterials. Jun, 2015  |   Pubmed ID: 25890741
• Characterization of a Novel Brain Barrier Ex Vivo Insect-based P-glycoprotein Screening Model
  Pharmacology Research & Perspectives. Aug, 2014  |   Pubmed ID: 25505597
• Primary Porcine Brain Microvessel Endothelial Cell Isolation and Culture
  Current Protocols in Neuroscience. Oct, 2014  |   Pubmed ID: 25297692
• In Vitro Porcine Blood-brain Barrier Model for Permeability Studies: PCEL-X Software PKa(FLUX) Method for Aqueous Boundary Layer Correction and Detailed Data Analysis
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Dec, 2014  |   Pubmed ID: 25239510
• A High-content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-like Kinase 1
  PloS One. 2013  |   Pubmed ID: 24204733
• A Multi-system Approach Assessing the Interaction of Anticonvulsants with P-gp
  PloS One. 2013  |   Pubmed ID: 23741405
• Blood-brain Barrier Structure and Function and the Challenges for CNS Drug Delivery
  Journal of Inherited Metabolic Disease. May, 2013  |   Pubmed ID: 23609350
• A Detailed Method for Preparation of a Functional and Flexible Blood-brain Barrier Model Using Porcine Brain Endothelial Cells
  Brain Research. Jul, 2013  |   Pubmed ID: 23603406
• Delivery of Paclitaxel Across Cellular Barriers Using a Dendrimer-based Nanocarrier
  International Journal of Pharmaceutics. Jan, 2013  |   Pubmed ID: 23089576
• Establishment of a Simplified in Vitro Porcine Blood-brain Barrier Model with High Transendothelial Electrical Resistance
  Brain Research. Jul, 2013  |   Pubmed ID: 22789905
• Overview and Introduction: the Blood-brain Barrier in Health and Disease
  Epilepsia. Nov, 2012  |   Pubmed ID: 23134489
• An Improved in Vitro Blood-brain Barrier Model: Rat Brain Endothelial Cells Co-cultured with Astrocytes
  Methods in Molecular Biology (Clifton, N.J.). 2012  |   Pubmed ID: 22144323
• Structure and Function of the Blood-brain Barrier
  Neurobiology of Disease. Jan, 2010  |   Pubmed ID: 19664713
• All Vertebrates Started out with a Glial Blood-brain Barrier 4-500 Million Years Ago
  Glia. May, 2008  |   Pubmed ID: 18338790
• Strategies to Advance Translational Research into Brain Barriers
  The Lancet. Neurology. Jan, 2008  |   Pubmed ID: 18093565
• P-Glycoprotein Expression in Human Retinal Pigment Epithelium Cell Lines
  Experimental Eye Research. Jul, 2006  |   Pubmed ID: 16530756
• Astrocyte-endothelial Interactions at the Blood-brain Barrier
  Nature Reviews. Neuroscience. Jan, 2006  |   Pubmed ID: 16371949
• Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation
  Cellular and Molecular Neurobiology. Feb, 2005  |   Pubmed ID: 15962506
• Induction of Aquaporin 1 but Not Aquaporin 4 Messenger RNA in Rat Primary Brain Microvessel Endothelial Cells in Culture
  Journal of Neurochemistry. May, 2005  |   Pubmed ID: 15857386
• Prediction of Blood-brain Barrier Permeation in Drug Discovery from in Vivo, in Vitro and in Silico Models
  Drug Discovery Today. Technologies. Dec, 2004  |   Pubmed ID: 24981621
• Interaction of Nucleoside Analogues with Nucleoside Transporters in Rat Brain Endothelial Cells
  Journal of Drug Targeting. Jun, 2004  |   Pubmed ID: 15512777
• 血液脳関門を開く副交感神経翼口蓋神経節の刺激によって： 新しいメソッドは脳への高分子配信。
  Journal of Neurosurgery. Aug, 2004  |   Pubmed ID: 15309923
• Brain to Blood Efflux Transport of Adenosine: Blood-brain Barrier Studies in the Rat
  Journal of Neurochemistry. Jul, 2004  |   Pubmed ID: 15228584
• Evidence for Bulk Flow of Brain Interstitial Fluid: Significance for Physiology and Pathology
  Neurochemistry International. Sep, 2004  |   Pubmed ID: 15186921
• Cross Reactivity of Polyclonal GFAP Antiserum: Implications for the In-vitro Characterisation of Brain Endothelium
  Brain Research. Jun, 2004  |   Pubmed ID: 15158176
• Flavonoid Permeability Across an in Situ Model of the Blood-brain Barrier
  Free Radical Biology & Medicine. Mar, 2004  |   Pubmed ID: 14980703
• In Vitro Trans-monolayer Permeability Calculations: Often Forgotten Assumptions
  Drug Discovery Today. Nov, 2003  |   Pubmed ID: 14643163
• An Overview of in Vitro Techniques for Blood-brain Barrier Studies
  Methods in Molecular Medicine. 2003  |   Pubmed ID: 12958429
• Functional Characterisation of Nucleoside Transport in Rat Brain Endothelial Cells
  Neuroreport. May, 2003  |   Pubmed ID: 12802208
• Vascular and Parenchymal Mechanisms in Multiple Drug Resistance: a Lesson from Human Epilepsy
  Current Drug Targets. May, 2003  |   Pubmed ID: 12699350
• Interaction Between Flavonoids and the Blood-brain Barrier: in Vitro Studies
  Journal of Neurochemistry. Apr, 2003  |   Pubmed ID: 12641740
• Lipids in Blood-brain Barrier Models in Vitro II: Influence of Glial Cells on Lipid Classes and Lipid Fatty Acids
  In Vitro Cellular & Developmental Biology. Animal. Nov-Dec, 2002  |   Pubmed ID: 12762838
• Lipids in Blood-brain Barrier Models in Vitro I: Thin-layer Chromatography and High-performance Liquid Chromatography for the Analysis of Lipid Classes and Long-chain Polyunsaturated Fatty Acids
  In Vitro Cellular & Developmental Biology. Animal. Nov-Dec, 2002  |   Pubmed ID: 12762837
• Bradykinin Increases Permeability by Calcium and 5-lipoxygenase in the ECV304/C6 Cell Culture Model of the Blood-brain Barrier
  Brain Research. Oct, 2002  |   Pubmed ID: 12384249
• Evaluation of the RBE4 Cell Line to Explore Carrier-mediated Drug Delivery to the CNS Via the L-system Amino Acid Transporter at the Blood-brain Barrier
  Journal of Drug Targeting. Jun, 2002  |   Pubmed ID: 12164376
• Astrocyte-endothelial Interactions and Blood-brain Barrier Permeability
  Journal of Anatomy. Jun, 2002  |   Pubmed ID: 12162730
• Ionic Currents in Isolated and in Situ Squid Schwann Cells
  The Journal of Physiology. Jun, 2002  |   Pubmed ID: 12068039
• Drug Resistance in Epilepsy: the Role of the Blood-brain Barrier
  Novartis Foundation Symposium. 2002  |   Pubmed ID: 11990780
• Understanding the Physiology of the Blood-Brain Barrier: In Vitro Models
  News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. Dec, 1998  |   Pubmed ID: 11390805