Nial J. Wheate

Publications

• A Cisplatin Slow-release Hydrogel Drug Delivery System Based on a Formulation of the Macrocycle Cucurbit[7]uril, Gelatin and Polyvinyl Alcohol
  Journal of Inorganic Biochemistry. May, 2014  |   Pubmed ID: 24595010
• Topical Cream-based Dosage Forms of the Macrocyclic Drug Delivery Vehicle Cucurbit[6]uril
  PloS One. 2014  |   Pubmed ID: 24454850
• DNA-based Aptamer Fails As a Simultaneous Cancer Targeting Agent and Drug Delivery Vehicle for a Phenanthroline-based Platinum(II) Complex
  Journal of Inorganic Biochemistry. Nov, 2013  |   Pubmed ID: 23954482
• Nanoparticles: the Future for Platinum Drugs or a Research Red Herring?
  Nanomedicine (London, England). Sep, 2012  |   Pubmed ID: 22994954
• Combining Aspects of the Platinum Anticancer Drugs Picoplatin and BBR3464 to Synthesize a New Family of Sterically Hindered Dinuclear Complexes; Their Synthesis, Binding Kinetics and Cytotoxicity
  Dalton Transactions (Cambridge, England : 2003). Oct, 2012  |   Pubmed ID: 22886151
• Cucurbit[7]uril Encapsulated Cisplatin Overcomes Cisplatin Resistance Via a Pharmacokinetic Effect
  Metallomics : Integrated Biometal Science. Jun, 2012  |   Pubmed ID: 22610518
• Cisplatin-tethered Gold Nanoparticles That Exhibit Enhanced Reproducibility, Drug Loading, and Stability: a Step Closer to Pharmaceutical Approval?
  Inorganic Chemistry. Mar, 2012  |   Pubmed ID: 22390791
• Evaluation of Anionic Half Generation 3.5-6.5 Poly(amidoamine) Dendrimers As Delivery Vehicles for the Active Component of the Anticancer Drug Cisplatin
  Journal of Inorganic Biochemistry. Sep, 2011  |   Pubmed ID: 21704583
• Microwave Synthesis of Cucurbit[n]urils
  Future Medicinal Chemistry. Feb, 2010  |   Pubmed ID: 21426190
• Synthesis, Processing and Solid State Excipient Interactions of Cucurbit[6]uril and Its Formulation into Tablets for Oral Drug Delivery
  Molecular Pharmaceutics. Dec, 2010  |   Pubmed ID: 20669974
• The Status of Platinum Anticancer Drugs in the Clinic and in Clinical Trials
  Dalton Transactions (Cambridge, England : 2003). Sep, 2010  |   Pubmed ID: 20593091
• Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin
  Journal of the American Chemical Society. Apr, 2010  |   Pubmed ID: 20225865
• Solid State Stabilisation of the Orally Delivered Drugs Atenolol, Glibenclamide, Memantine and Paracetamol Through Their Complexation with Cucurbit[7]uril
  Organic & Biomolecular Chemistry. Feb, 2010  |   Pubmed ID: 20135032
• A Chemical Preformulation Study of a Host-guest Complex of Cucurbit[7]uril and a Multinuclear Platinum Agent for Enhanced Anticancer Drug Delivery
  Dalton Transactions (Cambridge, England : 2003). Oct, 2009  |   Pubmed ID: 19759943
• Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer Cells
  Journal of Medicinal Chemistry. Sep, 2009  |   Pubmed ID: 19658404
• Diffusion-based Studies on the Self-stacking and Nanorod Formation of Platinum(II) Intercalators
  Chemical Communications (Cambridge, England). Mar, 2009  |   Pubmed ID: 19240876
• Side-on Binding of P-sulphonatocalix[4]arene to the Dinuclear Platinum Complex Trans-[{PtCl(NH3)2}2mu-dpzm]2+ and Its Implications for Anticancer Drug Delivery
  Journal of Inorganic Biochemistry. Mar, 2009  |   Pubmed ID: 19171382
• Anionic PAMAM Dendrimers As Drug Delivery Vehicles for Transition Metal-based Anticancer Drugs
  Journal of Inorganic Biochemistry. Mar, 2009  |   Pubmed ID: 19121543
• Improving Platinum(II)-based Anticancer Drug Delivery Using Cucurbit[n]urils
  Journal of Inorganic Biochemistry. Dec, 2008  |   Pubmed ID: 18653238
• Substituted Beta-cyclodextrin and Calix[4]arene As Encapsulatory Vehicles for Platinum(II)-based DNA Intercalators
  Inorganic Chemistry. Aug, 2008  |   Pubmed ID: 18597414
• Degradation of Bidentate-coordinated Platinum(II)-based DNA Intercalators by Reduced L-glutathione
  Journal of Medicinal Chemistry. May, 2008  |   Pubmed ID: 18412325
• Examination of Cucurbit[7]uril and Its Host-guest Complexes by Diffusion Nuclear Magnetic Resonance
  The Journal of Physical Chemistry. B. Feb, 2008  |   Pubmed ID: 18247599
• Novel Platinum(II)-based Anticancer Complexes and Molecular Hosts As Their Drug Delivery Vehicles
  Dalton Transactions (Cambridge, England : 2003). Nov, 2007  |   Pubmed ID: 17992290
• Encapsulation of Platinum(II)-based DNA Intercalators Within Cucurbit[6,7,8]urils
  Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Sep, 2007  |   Pubmed ID: 17653578
• DNA Intercalators in Cancer Therapy: Organic and Inorganic Drugs and Their Spectroscopic Tools of Analysis
  Mini Reviews in Medicinal Chemistry. Jun, 2007  |   Pubmed ID: 17584161
• The Effect of Ancillary Ligand Chirality and Phenanthroline Functional Group Substitution on the Cytotoxicity of Platinum(II)-based Metallointercalators
  Journal of Inorganic Biochemistry. Jul, 2007  |   Pubmed ID: 17544512
• Synthesis of DNA-sequence-selective Hairpin Polyamide Platinum Complexes
  Chemistry (Weinheim an Der Bergstrasse, Germany). 2007  |   Pubmed ID: 17226877
• Polyamide Platinum Anticancer Complexes Designed to Target Specific DNA Sequences
  Inorganic Chemistry. Jul, 2006  |   Pubmed ID: 16842007
• Cucurbit[n]uril Binding of Platinum Anticancer Complexes
  Dalton Transactions (Cambridge, England : 2003). Jan, 2006  |   Pubmed ID: 16395444
• Multi-nuclear Platinum Drugs: a New Paradigm in Chemotherapy
  Current Medicinal Chemistry. Anti-cancer Agents. May, 2005  |   Pubmed ID: 15992354
• Potential Adenine and Minor Groove Binding Platinum Complexes
  Journal of Inorganic Biochemistry. Oct, 2004  |   Pubmed ID: 15458819
• Multi-nuclear Platinum Complexes Encapsulated in Cucurbit[n]uril As an Approach to Reduce Toxicity in Cancer Treatment
  Chemical Communications (Cambridge, England). Jun, 2004  |   Pubmed ID: 15179496