Nicholas R.J. Gascoigne Department of Microbiology and Immunology, Yong Loo Lin School of Medicine National University of Singapore Biography Publications Institution JoVE Articles Nicholas R.J. Gascoigne has not added a biography. If you are Nicholas R.J. Gascoigne and would like to personalize this page please email our Author Liaison for assistance. Publications Defining the Structural Basis for Human Alloantibody Binding to Human Leukocyte Antigen Allele HLA-A*11:01 Nature Communications. Feb, 2019 | Pubmed ID: 30792391 Themis-associated Phosphatase Activity Controls Signaling in T Cell Development Proceedings of the National Academy of Sciences of the United States of America. 11, 2018 | Pubmed ID: 30413615 CD8 T Cells Have Commitment Issues Nature Immunology. Aug, 2018 | Pubmed ID: 30013145 Nonstimulatory Peptide-MHC Enhances Human T-cell Antigen-specific Responses by Amplifying Proximal TCR Signaling Nature Communications. 07, 2018 | Pubmed ID: 30006605 Development of a Screening Strategy for New Modulators of T Cell Receptor Signaling and T Cell Activation Scientific Reports. Jul, 2018 | Pubmed ID: 29968737 Monomeric TCRs Drive T Cell Antigen Recognition Nature Immunology. May, 2018 | Pubmed ID: 29662172 A High Content Imaging Flow Cytometry Approach to Study Mitochondria in T Cells: MitoTracker Green FM Dye Concentration Optimization Methods (San Diego, Calif.). 02, 2018 | Pubmed ID: 29198814 CD40L Expression Allows CD8 T Cells to Promote Their Own Expansion and Differentiation Through Dendritic Cells Frontiers in Immunology. 2017 | Pubmed ID: 29163545 TCR-like Antibodies Mediate Complement and Antibody-dependent Cellular Cytotoxicity Against Epstein-Barr Virus-transformed B Lymphoblastoid Cells Expressing Different HLA-A*02 Microvariants Scientific Reports. Aug, 2017 | Pubmed ID: 28855662 Thymic Origins of T Cell Receptor Alloreactivity Transplantation. 07, 2017 | Pubmed ID: 28114168 Molecular Engineering of a Therapeutic Antibody for Blo T 5-induced Allergic Asthma The Journal of Allergy and Clinical Immunology. 05, 2017 | Pubmed ID: 27923562 TCR Signal Strength and T Cell Development Annual Review of Cell and Developmental Biology. 10, 2016 | Pubmed ID: 27712102 SHP1-ing Thymic Selection European Journal of Immunology. 09, 2016 | Pubmed ID: 27600672 Vive La Peptide Différence! Nature Immunology. 07, 2016 | Pubmed ID: 27434001 Targeting Epstein-Barr Virus-transformed B Lymphoblastoid Cells Using Antibodies with T-cell Receptor-like Specificities Blood. 09, 2016 | Pubmed ID: 27338099 Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition Frontiers in Immunology. 2016 | Pubmed ID: 26870040 Identification of a Novel Lymphoid Population in the Murine Epidermis Scientific Reports. Jul, 2015 | Pubmed ID: 26223192 Virus-specific T Lymphocytes Home to the Skin During Natural Dengue Infection Science Translational Medicine. Mar, 2015 | Pubmed ID: 25761891 THEMIS: a Critical TCR Signal Regulator for Ligand Discrimination Current Opinion in Immunology. Apr, 2015 | Pubmed ID: 25700024 A THEMIS:SHP1 Complex Promotes T-cell Survival The EMBO Journal. Feb, 2015 | Pubmed ID: 25535246 Allelic Exclusion of TCR α-chains Upon Severe Restriction of Vα Repertoire PloS One. 2014 | Pubmed ID: 25500569 Immunology: Tolerance Lies in the Timing Nature. Nov, 2014 | Pubmed ID: 25428497 Ligand-engaged TCR is Triggered by Lck Not Associated with CD8 Coreceptor Nature Communications. Nov, 2014 | Pubmed ID: 25427562 Fine-tuning T Cell Receptor Signaling to Control T Cell Development Trends in Immunology. Jul, 2014 | Pubmed ID: 24951034 Protein Kinase C-η Controls CTLA-4-mediated Regulatory T Cell Function Nature Immunology. May, 2014 | Pubmed ID: 24705298 Themis Sets the Signal Threshold for Positive and Negative Selection in T-cell Development Nature. Dec, 2013 | Pubmed ID: 24226767 Too Fast to Die Science Signaling. Oct, 2013 | Pubmed ID: 24129699 人間 cd8 T 細胞活性化における Co 作動を調査する単一のチェーン MHC 技術の使用 Xiang Zhao1, Maryam Hamidinia1, Joanna Ai Ling Choo1, Chien Tei Too1,2, Zi Zong Ho3, Ee Chee Ren4, Antonio Bertoletti3, Paul A. MacAry1,2,5, Keith G. Gould6, Joanna Brzostek1, Nicholas R.J. Gascoigne1,2,5 1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Immunology Programme, Life Sciences Institute, National University of Singapore, 3Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, 4Singapore Immunology Network, A*STAR, 5NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, 6Department of Immunology, Wright-Fleming Institute, Imperial College London JoVE 59126 Immunology and Infection
人間 cd8 T 細胞活性化における Co 作動を調査する単一のチェーン MHC 技術の使用 Xiang Zhao1, Maryam Hamidinia1, Joanna Ai Ling Choo1, Chien Tei Too1,2, Zi Zong Ho3, Ee Chee Ren4, Antonio Bertoletti3, Paul A. MacAry1,2,5, Keith G. Gould6, Joanna Brzostek1, Nicholas R.J. Gascoigne1,2,5 1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Immunology Programme, Life Sciences Institute, National University of Singapore, 3Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, 4Singapore Immunology Network, A*STAR, 5NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, 6Department of Immunology, Wright-Fleming Institute, Imperial College London JoVE 59126 Immunology and Infection
