Nicholas M. Luscombe European Bioinformatics Institute EMBL Heidelberg Biography Publications Institution JoVE Articles Nicholas M. Luscombe has not added a biography. If you are Nicholas M. Luscombe and would like to personalize this page please email our Author Liaison for assistance. Publications How Do You Find Transcription Factors? Computational Approaches to Compile and Annotate Repertoires of Regulators for Any Genome Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 21938617 A Genomic Model of Condition-specific Nucleosome Behavior Explains Transcriptional Activity in Yeast Genome Research. Jan, 2012 | Pubmed ID: 21930892 Protein-RNA Interactions: New Genomic Technologies and Perspectives Nature Reviews. Genetics. Feb, 2011 | Pubmed ID: 22251872 SpeCond: a Method to Detect Condition-specific Gene Expression Genome Biology. Dec, 2011 | Pubmed ID: 22212554 Genomic Analysis of DNA Binding and Gene Regulation by Homologous Nucleoid-associated Proteins IHF and HU in Escherichia Coli K12 Nucleic Acids Research. Dec, 2011 | Pubmed ID: 22180530 SpeCond: a Method to Detect Condition-specific Gene Expression Genome Biology. Oct, 2011 | Pubmed ID: 22008066 Comparative Genomics Suggests Differential Deployment of Linear and Branched Signaling Across Bacteria Molecular BioSystems. Nov, 2011 | Pubmed ID: 21879110 The RNA-binding Protein Rrm4 is Essential for Efficient Secretion of Endochitinase Cts1 Molecular & Cellular Proteomics : MCP. Dec, 2011 | Pubmed ID: 21808052 Large-scale Nuclear Architecture and Transcriptional Control Sub-cellular Biochemistry. 2011 | Pubmed ID: 21557088 An Overview of Prokaryotic Transcription Factors : a Summary of Function and Occurrence in Bacterial Genomes Sub-cellular Biochemistry. 2011 | Pubmed ID: 21557077 Sensitized Phenotypic Screening Identifies Gene Dosage Sensitive Region on Chromosome 11 That Predisposes to Disease in Mice EMBO Molecular Medicine. Jan, 2011 | Pubmed ID: 21204268 Direct and Indirect Effects of H-NS and Fis on Global Gene Expression Control in Escherichia Coli Nucleic Acids Research. Mar, 2011 | Pubmed ID: 21097887 ICLIP Predicts the Dual Splicing Effects of TIA-RNA Interactions PLoS Biology. 2010 | Pubmed ID: 21048981 The Nonspecific Lethal Complex is a Transcriptional Regulator in Drosophila Molecular Cell. Jun, 2010 | Pubmed ID: 20620954 ICLIP Reveals the Function of HnRNP Particles in Splicing at Individual Nucleotide Resolution Nature Structural & Molecular Biology. Jul, 2010 | Pubmed ID: 20601959 Comparative Genomics of Cyclic-di-GMP Signalling in Bacteria: Post-translational Regulation and Catalytic Activity Nucleic Acids Research. Oct, 2010 | Pubmed ID: 20483912 Comprehensive Reanalysis of Transcription Factor Knockout Expression Data in Saccharomyces Cerevisiae Reveals Many New Targets Nucleic Acids Research. Aug, 2010 | Pubmed ID: 20385592 Genome Research. Jun, 2010 | Pubmed ID: 20378718 Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome PLoS Genetics. Feb, 2010 | Pubmed ID: 20174442 Know Your Limits: Assumptions, Constraints and Interpretation in Systems Biology Biochimica Et Biophysica Acta. Sep, 2009 | Pubmed ID: 19439202 A Census of Human Transcription Factors: Function, Expression and Evolution Nature Reviews. Genetics. Apr, 2009 | Pubmed ID: 19274049 Principles of Transcriptional Regulation and Evolution of the Metabolic System in E. Coli Genome Research. Jan, 2009 | Pubmed ID: 18836036 Genome-wide Analysis Reveals MOF As a Key Regulator of Dosage Compensation and Gene Expression in Drosophila Cell. May, 2008 | Pubmed ID: 18510926 Complete Genome Sequence of Uropathogenic Proteus Mirabilis, a Master of Both Adherence and Motility Journal of Bacteriology. Jun, 2008 | Pubmed ID: 18375554 Transcriptomics and Adaptive Genomics of the Asymptomatic Bacteriuria Escherichia Coli Strain 83972 Molecular Genetics and Genomics : MGG. May, 2008 | Pubmed ID: 18317809 Transcriptional Regulatory Networks in Bacteria: from Input Signals to Output Responses Current Opinion in Microbiology. Oct, 2006 | Pubmed ID: 16942903 Extrapolating Traditional DNA Microarray Statistics to Tiling and Protein Microarray Technologies Methods in Enzymology. 2006 | Pubmed ID: 16939796 Comprehensive Analysis of Combinatorial Regulation Using the Transcriptional Regulatory Network of Yeast Journal of Molecular Biology. Jun, 2006 | Pubmed ID: 16762362 Transcriptional Networking Genome Biology. 2005 | Pubmed ID: 16168097 GenCompass: a Universal System for Analysing Gene Expression for Any Genome Trends in Biotechnology. Nov, 2004 | Pubmed ID: 15491796 Genomic Analysis of Regulatory Network Dynamics Reveals Large Topological Changes Nature. Sep, 2004 | Pubmed ID: 15372033 Structure and Evolution of Transcriptional Regulatory Networks Current Opinion in Structural Biology. Jun, 2004 | Pubmed ID: 15193307 Annotation Transfer Between Genomes: Protein-protein Interologs and Protein-DNA Regulogs Genome Research. Jun, 2004 | Pubmed ID: 15173116 CREB Binds to Multiple Loci on Human Chromosome 22 Molecular and Cellular Biology. May, 2004 | Pubmed ID: 15082775 Prediction of Regulatory Networks: Genome-wide Identification of Transcription Factor Targets from Gene Expression Data Bioinformatics (Oxford, England). Oct, 2003 | Pubmed ID: 14555624 Distribution of NF-kappaB-binding Sites Across Human Chromosome 22 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14527995 Genomic Analysis of Gene Expression Relationships in Transcriptional Regulatory Networks Trends in Genetics : TIG. Aug, 2003 | Pubmed ID: 12902159 ExpressYourself: A Modular Platform for Processing and Visualizing Microarray Data Nucleic Acids Research. Jul, 2003 | Pubmed ID: 12824348 The Transcriptional Activity of Human Chromosome 22 Genes & Development. Feb, 2003 | Pubmed ID: 12600945 Complex Transcriptional Circuitry at the G1/S Transition in Saccharomyces Cerevisiae Genes & Development. Dec, 2002 | Pubmed ID: 12464632 The Dominance of the Population by a Selected Few: Power-law Behaviour Applies to a Wide Variety of Genomic Properties Genome Biology. Jul, 2002 | Pubmed ID: 12186647 Protein-DNA Interactions: Amino Acid Conservation and the Effects of Mutations on Binding Specificity Journal of Molecular Biology. Jul, 2002 | Pubmed ID: 12126620 Comprehensive Analysis of Amino Acid and Nucleotide Composition in Eukaryotic Genomes, Comparing Genes and Pseudogenes Nucleic Acids Research. Jun, 2002 | Pubmed ID: 12034841 GATA-1 Binding Sites Mapped in the Beta-globin Locus by Using Mammalian ChIp-chip Analysis Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11867748 Structural Genomics: a New Era for Pharmaceutical Research Genome Biology. 2002 | Pubmed ID: 11864367 Molecular Fossils in the Human Genome: Identification and Analysis of the Pseudogenes in Chromosomes 21 and 22 Genome Research. Feb, 2002 | Pubmed ID: 11827946 iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution Julian Konig1, Kathi Zarnack2, Gregor Rot3, Tomaz Curk3, Melis Kayikci1, Blaz Zupan3, Daniel J. Turner4, Nicholas M. Luscombe2, Jernej Ule1 1Laboratory of Molecular Biology, Medical Research Council - MRC, 2European Bioinformatics Institute, EMBL Heidelberg, 3Computer and Information Science, University of Ljubljana, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute JoVE 2638 Biology
iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution Julian Konig1, Kathi Zarnack2, Gregor Rot3, Tomaz Curk3, Melis Kayikci1, Blaz Zupan3, Daniel J. Turner4, Nicholas M. Luscombe2, Jernej Ule1 1Laboratory of Molecular Biology, Medical Research Council - MRC, 2European Bioinformatics Institute, EMBL Heidelberg, 3Computer and Information Science, University of Ljubljana, 4Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute JoVE 2638 Biology
