Nikolai Klymiuk Institute of Molecular Animal Breeding and Biotechnology Ludwig-Maximilian University Biography Publications Institution JoVE Articles Nikolai Klymiuk has not added a biography. If you are Nikolai Klymiuk and would like to personalize this page please email our Author Liaison for assistance. Publications Surface Modification of Pig Endothelial Cells with a Branched Heparin Conjugate Improves Their Compatibility with Human Blood Scientific Reports. Jun, 2017 | Pubmed ID: 28667310 Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-cell Interactions in Situ and is Altered After Transplantation Endocrinology. Jan, 2017 | Pubmed ID: 28324008 Transgenic Expression of Human Leukocyte Antigen-E Attenuates GalKO.hCD46 Porcine Lung Xenograft Injury Xenotransplantation. Mar, 2017 | Pubmed ID: 28258595 Direct Introduction of Gene Constructs into the Pronucleus-like Structure of Cloned Embryos: a New Strategy for the Generation of Genetically Modified Pigs Transgenic Research. Apr, 2017 | Pubmed ID: 27943082 Progressive Muscle Proteome Changes in a Clinically Relevant Pig Model of Duchenne Muscular Dystrophy Scientific Reports. Sep, 2016 | Pubmed ID: 27634466 Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs PloS One. 2016 | Pubmed ID: 27175998 Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation Transplantation. Sep, 2016 | Pubmed ID: 27077599 Chimeric 2C10R4 Anti-CD40 Antibody Therapy is Critical for Long-term Survival of GTKO.hCD46.hTBM Pig-to-primate Cardiac Xenograft Nature Communications. Apr, 2016 | Pubmed ID: 27045379 Inhibition of Complement Component C5 Prevents Clotting in an Ex Vivo Model of Xenogeneic Activation of Coagulation Xenotransplantation. Mar, 2016 | Pubmed ID: 26773447 Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies Toxicologic Pathology. Apr, 2016 | Pubmed ID: 26511847 Pre-clinical Heterotopic Intrathoracic Heart Xenotransplantation: a Possibly Useful Clinical Technique Xenotransplantation. Nov-Dec, 2015 | Pubmed ID: 26602740 Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets PloS One. 2015 | Pubmed ID: 26600426 Engraftment and Reversal of Diabetes After Intramuscular Transplantation of Neonatal Porcine Islet-like Clusters Xenotransplantation. Nov-Dec, 2015 | Pubmed ID: 26490671 Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b Without Apparent Phenotype PloS One. 2015 | Pubmed ID: 26474299 Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions Transplantation. Oct, 2015 | Pubmed ID: 25965410 Virus Safety of Islet Cell Transplantation from Transgenic Pigs to Marmosets Virus Research. Jun, 2015 | Pubmed ID: 25956348 Pig-to-baboon Heterotopic Heart Transplantation--exploratory Preliminary Experience with Pigs Transgenic for Human Thrombomodulin and Comparison of Three Costimulation Blockade-based Regimens Xenotransplantation. May-Jun, 2015 | Pubmed ID: 25847282 Complement Dependent Early Immunological Responses During Ex Vivo Xenoperfusion of HCD46/HLA-E Double Transgenic Pig Forelimbs with Human Blood Xenotransplantation. May-Jun, 2014 | Pubmed ID: 24635052 Homologous Recombination Contributes to the Repair of Zinc-finger-nuclease Induced Double Strand Breaks in Pig Primary Cells and Facilitates Recombination with Exogenous DNA Journal of Biotechnology. May, 2014 | Pubmed ID: 24613297 Regulatory Sequences of the Porcine THBD Gene Facilitate Endothelial-specific Expression of Bioactive Human Thrombomodulin in Single- and Multitransgenic Pigs Transplantation. Jan, 2014 | Pubmed ID: 24150517 Activation of the Lectin Pathway of Complement in Pig-to-human Xenotransplantation Models Transplantation. Nov, 2013 | Pubmed ID: 23958924 Dystrophin-deficient Pigs Provide New Insights into the Hierarchy of Physiological Derangements of Dystrophic Muscle Human Molecular Genetics. Nov, 2013 | Pubmed ID: 23784375 Factors Influencing the Efficiency of Generating Genetically Engineered Pigs by Nuclear Transfer: Multi-factorial Analysis of a Large Data Set BMC Biotechnology. May, 2013 | Pubmed ID: 23688045 Permanent Neonatal Diabetes in INS(C94Y) Transgenic Pigs Diabetes. May, 2013 | Pubmed ID: 23274907 Potential of Primary Kidney Cells for Somatic Cell Nuclear Transfer Mediated Transgenesis in Pig BMC Biotechnology. Nov, 2012 | Pubmed ID: 23140586 Xenografted Islet Cell Clusters from INSLEA29Y Transgenic Pigs Rescue Diabetes and Prevent Immune Rejection in Humanized Mice Diabetes. Jun, 2012 | Pubmed ID: 22522620 The Porcine Chloride Channel Calcium-activated Family Member PCLCA4a Mirrors Lung Expression of the Human HCLCA4 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jan, 2012 | Pubmed ID: 22205680 First Inducible Transgene Expression in Porcine Large Animal Models FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2012 | Pubmed ID: 22138035 Tissue and Cellular Expression Patterns of Porcine CFTR: Similarities to and Differences from Human CFTR The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Sep, 2010 | Pubmed ID: 20498480 Transgenic Pigs As Models for Translational Biomedical Research Journal of Molecular Medicine (Berlin, Germany). Jul, 2010 | Pubmed ID: 20339830 Transgenic Pigs for Xenotransplantation: Selection of Promoter Sequences for Reliable Transgene Expression Current Opinion in Organ Transplantation. Apr, 2010 | Pubmed ID: 20061949 Genetic Modification of Pigs As Organ Donors for Xenotransplantation Molecular Reproduction and Development. Mar, 2010 | Pubmed ID: 19998476 Genomic, Tissue Expression, and Protein Characterization of PCLCA1, a Putative Modulator of Cystic Fibrosis in the Pig The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Dec, 2009 | Pubmed ID: 19755716 Concise Classification of the Genomic Porcine Endogenous Retroviral Gamma1 Load to Defined Lineages Virology. Feb, 2008 | Pubmed ID: 17964627 Phylogeny, Recombination and Expression of Porcine Endogenous Retrovirus Gamma2 Nucleotide Sequences The Journal of General Virology. Apr, 2006 | Pubmed ID: 16528048 Reliable Classification and Recombination Analysis of Porcine Endogenous Retroviruses Virus Genes. May, 2005 | Pubmed ID: 15830154 Characterization of Endogenous Retroviruses in Sheep Journal of Virology. Oct, 2003 | Pubmed ID: 14512574 Recombination Analysis of Human-tropic Porcine Endogenous Retroviruses The Journal of General Virology. Oct, 2003 | Pubmed ID: 13679607 Characterization of Porcine Endogenous Retrovirus Gamma Pro-pol Nucleotide Sequences Journal of Virology. Nov, 2002 | Pubmed ID: 12388734 Vurdering av antikoagulerende og anti-inflammatorisk egenskaper av endotelceller 3D cellekultur og ikke-anticoagulated fullblod Riccardo Sfriso1,2, Anjan Bongoni3, Yara Banz4, Nikolai Klymiuk5, Eckhard Wolf5, Robert Rieben1 1Department of Clinical Research, University of Bern, 2Graduate School for Cellular and Biomedical Sciences, University of Bern, 3Immunology Research Centre, St. Vincent's Hospital Melbourne, 4Institute of Pathology, University of Bern, 5Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University JoVE 56227 Medicine
Vurdering av antikoagulerende og anti-inflammatorisk egenskaper av endotelceller 3D cellekultur og ikke-anticoagulated fullblod Riccardo Sfriso1,2, Anjan Bongoni3, Yara Banz4, Nikolai Klymiuk5, Eckhard Wolf5, Robert Rieben1 1Department of Clinical Research, University of Bern, 2Graduate School for Cellular and Biomedical Sciences, University of Bern, 3Immunology Research Centre, St. Vincent's Hospital Melbourne, 4Institute of Pathology, University of Bern, 5Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University JoVE 56227 Medicine
