Nikolaus Plesnila Institute for Stroke and Dementia Research University Hospital Munich Biography Publications Institution JoVE Articles Nikolaus Plesnila has not added a biography. If you are Nikolaus Plesnila and would like to personalize this page please email our Author Liaison for assistance. Publications CO2 Has No Therapeutic Effect on Early Microvasospasm After Experimental Subarachnoid Hemorrhage Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2014 | Pubmed ID: 24865999 Sustained Alterations of Hypothalamic Tanycytes During Posttraumatic Hypopituitarism in Male Mice Endocrinology. May, 2014 | Pubmed ID: 24601879 Preclinical Phase III Trials in Translational Stroke Research: Call for Collective Design of Framework and Guidelines Stroke; a Journal of Cerebral Circulation. Feb, 2014 | Pubmed ID: 24407954 Inhaled Nitric Oxide Protects Males but Not Females from Neonatal Mouse Hypoxia-ischemia Brain Injury Translational Stroke Research. Apr, 2013 | Pubmed ID: 24323275 A Semi-automated Method for Isolating Functionally Intact Mitochondria from Cultured Cells and Tissue Biopsies Analytical Biochemistry. Dec, 2013 | Pubmed ID: 23969012 Pathophysiological Role of Global Cerebral Ischemia Following Subarachnoid Hemorrhage: The Current Experimental Evidence Stroke Research and Treatment. 2013 | Pubmed ID: 23844316 Bradykinin in Blood and Cerebrospinal Fluid After Acute Cerebral Lesions: Correlations with Cerebral Edema and Intracranial Pressure Journal of Neurotrauma. Oct, 2013 | Pubmed ID: 23638655 Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog. [corrected] Cell Stem Cell. Apr, 2013 | Pubmed ID: 23561443 In Vivo Temporal and Spatial Profile of Leukocyte Adhesion and Migration After Experimental Traumatic Brain Injury in Mice Journal of Neuroinflammation. 2013 | Pubmed ID: 23448240 Arginine Vasopressin V1a Receptor-deficient Mice Have Reduced Brain Edema and Secondary Brain Damage Following Traumatic Brain Injury Journal of Neurotrauma. Aug, 2013 | Pubmed ID: 23441636 Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction The Journal of Biological Chemistry. Apr, 2013 | Pubmed ID: 23430260 Inhaled Nitric Oxide Reduces Secondary Brain Damage After Traumatic Brain Injury in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2013 | Pubmed ID: 23188422 Connexin 36 Promotes Cortical Spreading Depolarization and Ischemic Brain Damage Brain Research. Oct, 2012 | Pubmed ID: 22960118 Inhalation of NO During Myocardial Ischemia Reduces Infarct Size and Improves Cardiac Function Intensive Care Medicine. Aug, 2012 | Pubmed ID: 22653370 Impact of Anesthesia on Pathophysiology and Mortality Following Subarachnoid Hemorrhage in Rats Experimental & Translational Stroke Medicine. 2012 | Pubmed ID: 22414527 Paving the Road to Translation Cerebrovascular Diseases (Basel, Switzerland). 2012 | Pubmed ID: 22343133 Nitric Oxide: Considerations for the Treatment of Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2012 | Pubmed ID: 22333622 Inhalation of Nitric Oxide Prevents Ischemic Brain Damage in Experimental Stroke by Selective Dilatation of Collateral Arterioles Circulation Research. Mar, 2012 | Pubmed ID: 22207711 Experimental Subarachnoid Hemorrhage Causes Early and Long-lasting Microarterial Constriction and Microthrombosis: an In-vivo Microscopy Study Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2012 | Pubmed ID: 22146194 Vasopressin V(1a) Receptors Mediate Posthemorrhagic Systemic Hypertension Thereby Determining Rebleeding Rate and Outcome After Experimental Subarachnoid Hemorrhage Stroke; a Journal of Cerebral Circulation. Jan, 2012 | Pubmed ID: 21998059 Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome Following Experimental Subarachnoid Hemorrhage Cerebrovascular Diseases (Basel, Switzerland). 2011 | Pubmed ID: 21912109 Role of Apoptosis Inducing Factor (AIF) for Hippocampal Neuronal Cell Death Following Global Cerebral Ischemia in Mice Neuroscience Letters. Jul, 2011 | Pubmed ID: 21616126 In Vivo Contributions of BH3-only Proteins to Neuronal Death Following Seizures, Ischemia, and Traumatic Brain Injury Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2011 | Pubmed ID: 21364604 Fluid Resuscitation After Traumatic Brain Injury with Hypovolemic Shock: Still a Bloody Business? Critical Care Medicine. Mar, 2011 | Pubmed ID: 21330861 Contribution of Bradykinin Receptors to the Development of Secondary Brain Damage After Experimental Subarachnoid Hemorrhage Neurosurgery. Apr, 2011 | Pubmed ID: 21242838 Dopaminergic Neurons of System X(c)⁻-deficient Mice Are Highly Protected Against 6-hydroxydopamine-induced Toxicity FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2011 | Pubmed ID: 21191088 Characterization of a 3-vessel Occlusion Model for the Induction of Complete Global Cerebral Ischemia in Mice Journal of Neuroscience Methods. Oct, 2010 | Pubmed ID: 20688105 BH3-only Protein Bid is Dispensable for Seizure-induced Neuronal Death and the Associated Nuclear Accumulation of Apoptosis-inducing Factor Journal of Neurochemistry. Oct, 2010 | Pubmed ID: 20646170 Standardized Induction of Subarachnoid Hemorrhage in Mice by Intracranial Pressure Monitoring Journal of Neuroscience Methods. Jul, 2010 | Pubmed ID: 20457182 High Cortical Spreading Depression Susceptibility and Migraine-associated Symptoms in Ca(v)2.1 S218L Mice Annals of Neurology. Jan, 2010 | Pubmed ID: 20186955 Bid Mediates Fission, Membrane Permeabilization and Peri-nuclear Accumulation of Mitochondria As a Prerequisite for Oxidative Neuronal Cell Death Brain, Behavior, and Immunity. Jul, 2010 | Pubmed ID: 19961923 Temporal Profile of Thrombogenesis in the Cerebral Microcirculation After Traumatic Brain Injury in Mice Journal of Neurotrauma. Jan, 2010 | Pubmed ID: 19803784 The Role of Bradykinin B(1) and B(2) Receptors for Secondary Brain Damage After Traumatic Brain Injury in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2010 | Pubmed ID: 19773800 Level Alterations of the 2f (1)-f (2) Distortion Product Due to Hypoxia in the Guinea Pig Depend on the Stimulus Frequency European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. Mar, 2010 | Pubmed ID: 19629511 Mild Hypothermia (33 Degrees C) Reduces Intracranial Hypertension and Improves Functional Outcome After Subarachnoid Hemorrhage in Rats Neurosurgery. Aug, 2009 | Pubmed ID: 19625915 The Novel Nitric Oxide Synthase Inhibitor 4-amino-tetrahydro-L-biopterine Prevents Brain Edema Formation and Intracranial Hypertension Following Traumatic Brain Injury in Mice Journal of Neurotrauma. Nov, 2009 | Pubmed ID: 19514849 Inhibition of Bradykinin B2 Receptors Before, Not After Onset of Experimental Subarachnoid Hemorrhage Prevents Brain Edema Formation and Improves Functional Outcome Critical Care Medicine. Jul, 2009 | Pubmed ID: 19487935 Anatibant, a Selective Non-peptide Bradykinin B2 Receptor Antagonist, Reduces Intracranial Hypertension and Histopathological Damage After Experimental Traumatic Brain Injury Neuroscience Letters. Apr, 2009 | Pubmed ID: 19429066 Brain Edema Formation and Neurological Impairment After Subarachnoid Hemorrhage in Rats. Laboratory Investigation Journal of Neurosurgery. Nov, 2009 | Pubmed ID: 19425896 Effects of Transient Focal Cerebral Ischemia in Mice Deficient in Puma Neuroscience Letters. Feb, 2009 | Pubmed ID: 19159665 Role of Vasopressin V(1a) and V2 Receptors for the Development of Secondary Brain Damage After Traumatic Brain Injury in Mice Journal of Neurotrauma. Dec, 2008 | Pubmed ID: 19118456 Causal Role of Apoptosis-inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury The American Journal of Pathology. Dec, 2008 | Pubmed ID: 18988795 Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-lipoxygenase Dependent- and AIF-mediated Cell Death Cell Metabolism. Sep, 2008 | Pubmed ID: 18762024 Expression and Functional Role of Potassium-chloride Cotransporters (KCC) in Astrocytes and C6 Glioma Cells Neuroscience Letters. Sep, 2008 | Pubmed ID: 18638521 Changes of Cerebral Blood Flow During the Secondary Expansion of a Cortical Contusion Assessed by 14C-iodoantipyrine Autoradiography in Mice Using a Non-invasive Protocol Journal of Neurotrauma. Jul, 2008 | Pubmed ID: 18627253 Egr-1 Regulates Expression of the Glial Scar Component Phosphacan in Astrocytes After Experimental Stroke The American Journal of Pathology. Jul, 2008 | Pubmed ID: 18556777 Role of Cortical Spreading Depressions for Secondary Brain Damage After Traumatic Brain Injury in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2008 | Pubmed ID: 18414497 Complex Level Alterations of the 2f (1)-f (2) Distortion Product Due to Hypoxia in the Guinea Pig European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. Nov, 2008 | Pubmed ID: 18389267 Enantio-selective Effects of Clenbuterol in Cultured Neurons and Astrocytes, and in a Mouse Model of Cerebral Ischemia European Journal of Pharmacology. Dec, 2007 | Pubmed ID: 17869242 Aldolase C-positive Cerebellar Purkinje Cells Are Resistant to Delayed Death After Cerebral Trauma and AMPA-mediated Excitotoxicity The European Journal of Neuroscience. Aug, 2007 | Pubmed ID: 17686042 Decompression Craniectomy After Traumatic Brain Injury: Recent Experimental Results Progress in Brain Research. 2007 | Pubmed ID: 17618993 Characterization of Microvascular Basal Lamina Damage and Blood-brain Barrier Dysfunction Following Subarachnoid Hemorrhage in Rats Brain Research. Apr, 2007 | Pubmed ID: 17303089 Bone Marrow Stromal Cells Mediate Protection Through Stimulation of PI3-K/Akt and MAPK Signaling in Neurons Neurochemistry International. Jan, 2007 | Pubmed ID: 17050038 Non-invasive Intraoperative Monitoring of Blood Pressure and Arterial PCO2 During Surgical Anesthesia in Mice Journal of Neuroscience Methods. Jan, 2007 | Pubmed ID: 16945419 Effect of Oxidative Stress on Glial Cell Volume Journal of Neurotrauma. Nov, 2006 | Pubmed ID: 17115914 Structure-activity Relationships by Interligand NOE-based Design and Synthesis of Antiapoptotic Compounds Targeting Bid Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16891420 Effect of Early and Delayed Decompressive Craniectomy on Secondary Brain Damage After Controlled Cortical Impact in Mice Journal of Neurotrauma. Jul, 2006 | Pubmed ID: 16866621 An Inhibitor of Tau Hyperphosphorylation Prevents Severe Motor Impairments in Tau Transgenic Mice Proceedings of the National Academy of Sciences of the United States of America. Jun, 2006 | Pubmed ID: 16769887 Therapeutic Window of Bradykinin B2 Receptor Inhibition After Focal Cerebral Ischemia in Rats Neurochemistry International. Oct, 2006 | Pubmed ID: 16624448 Influence of the Duration of Ischemia and Reperfusion on Infarct Volume and Microvascular Damage in Mice Neurological Research. Mar, 2006 | Pubmed ID: 16551441 Lactacidosis-induced Glial Cell Swelling Depends on Extracellular Ca2+ Neuroscience Letters. May, 2006 | Pubmed ID: 16469448 Simultaneous Bilateral Laser Doppler Fluxmetry and Electrophysiological Recording During Middle Cerebral Artery Occlusion in Rats Journal of Neuroscience Methods. Jun, 2006 | Pubmed ID: 16439028 Arterial Hypotension Triggers Perifocal Depolarizations and Aggravates Secondary Damage in Focal Brain Injury Brain Research. Feb, 2006 | Pubmed ID: 16412395 Hypertonic Fluid Resuscitation from Subarachnoid Hemorrhage in Rats: a Comparison Between Small Volume Resuscitation and Mannitol Journal of the Neurological Sciences. Feb, 2006 | Pubmed ID: 16343544 Apoptosis-inducing Factor Triggered by Poly(ADP-ribose) Polymerase and Bid Mediates Neuronal Cell Death After Oxygen-glucose Deprivation and Focal Cerebral Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2005 | Pubmed ID: 16267234 Platelet Adhesion Via Glycoprotein IIb Integrin is Critical for Atheroprogression and Focal Cerebral Ischemia: an in Vivo Study in Mice Lacking Glycoprotein IIb Circulation. Aug, 2005 | Pubmed ID: 16103235 Cluster Analysis: a Useful Tool for the Analysis of Cerebral Laser-Doppler Scanning Data Journal of Neuroscience Methods. Jul, 2005 | Pubmed ID: 15935225 Motoneuron Survival After C7 Nerve Root Avulsion and Replantation in the Adult Rabbit: Effects of Local Ciliary Neurotrophic Factor and Brain-derived Neurotrophic Factor Application Plastic and Reconstructive Surgery. Jun, 2005 | Pubmed ID: 15923853 Release of Bradykinin and Expression of Kinin B2 Receptors in the Brain: Role for Cell Death and Brain Edema Formation After Focal Cerebral Ischemia in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2005 | Pubmed ID: 15815587 Role of Arginine Vasopressin V1 and V2 Receptors for Brain Damage After Transient Focal Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2005 | Pubmed ID: 15744246 Identification of Brain Tissue Necrosis by MRI: Validation by Histomorphometry Journal of Neurotrauma. Jun, 2004 | Pubmed ID: 15253801 Leukocyte-endothelium Interactions During Permanent Focal Cerebral Ischemia in Mice Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jun, 2004 | Pubmed ID: 15181374 Nuclear Translocation of Apoptosis-inducing Factor After Focal Cerebral Ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2004 | Pubmed ID: 15087715 Combination Therapy in Ischemic Stroke: Synergistic Neuroprotective Effects of Memantine and Clenbuterol Stroke; a Journal of Cerebral Circulation. May, 2004 | Pubmed ID: 15060319 Effect of Decompression Craniotomy on Increase of Contusion Volume and Functional Outcome After Controlled Cortical Impact in Mice Journal of Neurotrauma. Dec, 2003 | Pubmed ID: 14748979 Combination Drug Therapy and Mild Hypothermia After Transient Focal Cerebral Ischemia in Rats Stroke; a Journal of Cerebral Circulation. Sep, 2003 | Pubmed ID: 12893947 Relative Cerebral Blood Flow During the Secondary Expansion of a Cortical Lesion in Rats Neuroscience Letters. Jul, 2003 | Pubmed ID: 12821177 Neuroprotection in Transient Focal Cerebral Ischemia by Combination Drug Therapy and Mild Hypothermia: Comparison with Customary Therapeutic Regimen Stroke; a Journal of Cerebral Circulation. Jun, 2003 | Pubmed ID: 12730554 Caspase Activation and Neuroprotection in Caspase-3- Deficient Mice After in Vivo Cerebral Ischemia and in Vitro Oxygen Glucose Deprivation Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002 | Pubmed ID: 12415117 Lipid-sugar Particles for Intracranial Drug Delivery: Safety and Biocompatibility Brain Research. Aug, 2002 | Pubmed ID: 12137923 Nitric Oxide in the Penumbra of a Focal Cortical Necrosis in Rats Neuroscience Letters. May, 2002 | Pubmed ID: 12009523 Release of Excitatory Amino Acids in the Penumbra of a Focal Cortical Necrosis Journal of Neurotrauma. Apr, 2002 | Pubmed ID: 11990352 Function of BID -- a Molecule of the Bcl-2 Family -- in Ischemic Cell Death in the Brain European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes. Jan-Apr, 2002 | Pubmed ID: 11867899 Measurement of Absolute Values of Hemoglobin Oxygenation in the Brain of Small Rodents by Near Infrared Reflection Spectrophotometry Journal of Neuroscience Methods. Mar, 2002 | Pubmed ID: 11856562 चूहे में मॉडलिंग स्ट्रोक: दूरस्थ मध्य मस्तिष्क धमनी की स्थायी जमावट Gemma Llovera*1,2, Stefan Roth*1,2, Nikolaus Plesnila1,2, Roland Veltkamp3,4, Arthur Liesz1,2 1Institute for Stroke and Dementia Research, University Hospital Munich, 2Munich Cluster for Systems Neurology (SyNergy), 3Department of Neurology, University Heidelberg, 4Imperial College, Charing Cross Hospital JoVE 51729 Medicine Subarachnoid नकसीर की एक murine मॉडल Kathrin Schüller1, Dominik Bühler1, Nikolaus Plesnila1 1Institute for Stroke and Dementia Research (ISD), University of Munich Medical Center JoVE 50845 Medicine
चूहे में मॉडलिंग स्ट्रोक: दूरस्थ मध्य मस्तिष्क धमनी की स्थायी जमावट Gemma Llovera*1,2, Stefan Roth*1,2, Nikolaus Plesnila1,2, Roland Veltkamp3,4, Arthur Liesz1,2 1Institute for Stroke and Dementia Research, University Hospital Munich, 2Munich Cluster for Systems Neurology (SyNergy), 3Department of Neurology, University Heidelberg, 4Imperial College, Charing Cross Hospital JoVE 51729 Medicine
Subarachnoid नकसीर की एक murine मॉडल Kathrin Schüller1, Dominik Bühler1, Nikolaus Plesnila1 1Institute for Stroke and Dementia Research (ISD), University of Munich Medical Center JoVE 50845 Medicine
