Nina Bhardwaj Division of Hematology and Oncology, Hess Center for Science and Medicine Mount Sinai Medical Center Biography Publications Institution JoVE Articles Nina Bhardwaj has not added a biography. If you are Nina Bhardwaj and would like to personalize this page please email our Author Liaison for assistance. Publications Therapeutic In-Situ Autovaccination Against Solid Cancers with Intratumoral Poly-ICLC: Case Report, Hypothesis, and Clinical Trial Cancer Immunology Research. May, 2014 | Pubmed ID: 24801836 Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 Blockade Cancer Immunology Research. May, 2014 | Pubmed ID: 24795354 Dissection of Immune Gene Networks in Primary Melanoma Tumors Critical for Antitumor Surveillance of Patients with Stage II-III Resectable Disease The Journal of Investigative Dermatology. Feb, 2014 | Pubmed ID: 24522433 Dendritic Cells in Progression and Pathology of HIV Infection Trends in Immunology. Mar, 2014 | Pubmed ID: 24246474 HIV Type 1 Infection of Plasmacytoid and Myeloid Dendritic Cells is Restricted by High Levels of SAMHD1 and Cannot Be Counteracted by Vpx AIDS Research and Human Retroviruses. Feb, 2014 | Pubmed ID: 23924154 Dendritic Cell-Targeted Approaches to Modulate Immune Dysfunction in the Tumor Microenvironment Frontiers in Immunology. 2013 | Pubmed ID: 24339825 Impact of MAPK Pathway Activation in BRAF(V600) Melanoma on T Cell and Dendritic Cell Function Frontiers in Immunology. 2013 | Pubmed ID: 24194739 A Bloody Mess: Dendritic Cells Use Hemophagocytosis to Regulate Viral Inflammation Immunity. Sep, 2013 | Pubmed ID: 24054326 Active Systemic Lupus Erythematosus is Associated with Decreased Blood Conventional Dendritic Cells Experimental and Molecular Pathology. Jun, 2013 | Pubmed ID: 23773850 Dendritic Cell Dysregulation During HIV-1 Infection Immunological Reviews. Jul, 2013 | Pubmed ID: 23772620 Dendritic Cell Immunotherapy Annals of the New York Academy of Sciences. May, 2013 | Pubmed ID: 23651191 Antigen Depots: T Cell Traps? Nature Medicine. Apr, 2013 | Pubmed ID: 23558621 Phenotypic Properties of Transmitted Founder HIV-1 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23542380 Influenza, but Not HIV-specific CTL Epitopes, Elicits Delayed-type Hypersensitivity (DTH) Reactions in HIV-infected Patients European Journal of Immunology. Jun, 2013 | Pubmed ID: 23504637 Aspirin Attenuates Platelet Activation and Immune Activation in HIV-1-Infected Subjects on Antiretroviral Therapy: A Pilot Study Journal of Acquired Immune Deficiency Syndromes (1999). Jul, 2013 | Pubmed ID: 23406976 Inhibition of Both BRAF and MEK in BRAF(V600E) Mutant Melanoma Restores Compromised Dendritic Cell (DC) Function While Having Differential Direct Effects on DC Properties Cancer Immunology, Immunotherapy : CII. Apr, 2013 | Pubmed ID: 23306863 Plasmacytoid Dendritic Cells in HIV Infection Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 22975872 HIV-1 Infection-induced Apoptotic Microparticles Inhibit Human DCs Via CD44 The Journal of Clinical Investigation. Dec, 2012 | Pubmed ID: 23160198 Plasma Factors During Chronic HIV-1 Infection Impair IL-12 Secretion by Myeloid Dendritic Cells Via a Virus-independent Pathway Journal of Acquired Immune Deficiency Syndromes (1999). Dec, 2012 | Pubmed ID: 22902724 Activation of the Noncanonical NF-κB Pathway by HIV Controls a Dendritic Cell Immunoregulatory Phenotype Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22879398 Topical TLR7 Agonist Imiquimod Can Induce Immune-mediated Rejection of Skin Metastases in Patients with Breast Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2012 | Pubmed ID: 22767669 Dysregulation of Anti-tumor Immunity by the Matrix Metalloproteinase-2 Oncoimmunology. Jan, 2012 | Pubmed ID: 22720227 Immune Response in Melanoma: an In-depth Analysis of the Primary Tumor and Corresponding Sentinel Lymph Node Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jul, 2012 | Pubmed ID: 22425909 Plasmacytoid Dendritic Cells Lead the Charge Against Tumors The Journal of Clinical Investigation. Feb, 2012 | Pubmed ID: 22251700 MiR-30b/30d Regulation of GalNAc Transferases Enhances Invasion and Immunosuppression During Metastasis Cancer Cell. Jul, 2011 | Pubmed ID: 21741600 TLR4 Engagement During TLR3-induced Proinflammatory Signaling in Dendritic Cells Promotes IL-10-mediated Suppression of Antitumor Immunity Cancer Research. Aug, 2011 | Pubmed ID: 21730023 MAGE-A Inhibits Apoptosis in Proliferating Myeloma Cells Through Repression of Bax and Maintenance of Survivin Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2011 | Pubmed ID: 21565982 Human Immunodeficiency Virus Type 1 Modified to Package Simian Immunodeficiency Virus Vpx Efficiently Infects Macrophages and Dendritic Cells Journal of Virology. Jul, 2011 | Pubmed ID: 21507971 CTLA-4 Blockade Increases Antigen-specific CD8(+) T Cells in Prevaccinated Patients with Melanoma: Three Cases Cancer Immunology, Immunotherapy : CII. Aug, 2011 | Pubmed ID: 21465316 Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells Via an IL-12- and OX40L-dependent Pathway Cancer Cell. Mar, 2011 | Pubmed ID: 21397857 DCs and NK Cells: Critical Effectors in the Immune Response to HIV-1 Nature Reviews. Immunology. Mar, 2011 | Pubmed ID: 21350578 Spatiotemporal Trafficking of HIV in Human Plasmacytoid Dendritic Cells Defines a Persistently IFN-α-producing and Partially Matured Phenotype The Journal of Clinical Investigation. Mar, 2011 | Pubmed ID: 21339641 Oligonucleotide Motifs That Disappear During the Evolution of Influenza Virus in Humans Increase Alpha Interferon Secretion by Plasmacytoid Dendritic Cells Journal of Virology. Apr, 2011 | Pubmed ID: 21307198 LXR Promotes the Maximal Egress of Monocyte-derived Cells from Mouse Aortic Plaques During Atherosclerosis Regression The Journal of Clinical Investigation. Dec, 2010 | Pubmed ID: 21041949 Toll-like Receptor Agonists: Are They Good Adjuvants? Cancer Journal (Sudbury, Mass.). Jul-Aug, 2010 | Pubmed ID: 20693851 Evidence of Dysregulation of Dendritic Cells in Primary HIV Infection Blood. Nov, 2010 | Pubmed ID: 20693428 A Needle in the 'cancer Vaccine' Haystack Nature Medicine. Aug, 2010 | Pubmed ID: 20689546 CD8+ T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells PloS One. 2010 | Pubmed ID: 20585396 Directing Dendritic Cell Immunotherapy Towards Successful Cancer Treatment Immunotherapy. Jan, 2010 | Pubmed ID: 20473346 HIV-1 Impairs in Vitro Priming of Naïve T Cells and Gives Rise to Contact-dependent Suppressor T Cells European Journal of Immunology. Aug, 2010 | Pubmed ID: 20455275 Cellular Immune Responses Against CT7 (MAGE-C1) and Humoral Responses Against Other Cancer-testis Antigens in Multiple Myeloma Patients Cancer Immunity. 2010 | Pubmed ID: 20108890 Developing a Multidisciplinary Prospective Melanoma Biospecimen Repository to Advance Translational Research American Journal of Translational Research. 2009 | Pubmed ID: 19966936 Resolution of Immune Activation Defines Nonpathogenic SIV Infection The Journal of Clinical Investigation. Dec, 2009 | Pubmed ID: 19959871 Immune Profile and Mitotic Index of Metastatic Melanoma Lesions Enhance Clinical Staging in Predicting Patient Survival Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19915147 Dendritic Cells As Targets for Therapy in Rheumatoid Arthritis Nature Reviews. Rheumatology. Oct, 2009 | Pubmed ID: 19798032 Vaccination with Recombinant NY-ESO-1 Protein Elicits Immunodominant HLA-DR52b-restricted CD4+ T Cell Responses with a Conserved T Cell Receptor Repertoire Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009 | Pubmed ID: 19531622 A Randomized Therapeutic Vaccine Trial of Canarypox-HIV-pulsed Dendritic Cells Vs. Canarypox-HIV Alone in HIV-1-infected Patients on Antiretroviral Therapy Vaccine. Oct, 2009 | Pubmed ID: 19450647 Hematopoietic Progenitor Kinase 1 is a Negative Regulator of Dendritic Cell Activation Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19414772 Phosphorylated 4E-BP1 is Associated with Poor Survival in Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19336517 Vaccination with a Recombinant Protein Encoding the Tumor-specific Antigen NY-ESO-1 Elicits an A2/157-165-specific CTL Repertoire Structurally Distinct and of Reduced Tumor Reactivity Than That Elicited by Spontaneous Immune Responses to NY-ESO-1-expressing Tumors Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb-Mar, 2009 | Pubmed ID: 19238015 Aberrant MiR-182 Expression Promotes Melanoma Metastasis by Repressing FOXO3 and Microphthalmia-associated Transcription Factor Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19188590 In Vitro Priming Recapitulates in Vivo HIV-1 Specific T Cell Responses, Revealing Rapid Loss of Virus Reactive CD4 T Cells in Acute HIV-1 Infection PloS One. 2009 | Pubmed ID: 19165342 HLA Class I - Associated Immunodominance Affects CTL Responsiveness to an ESO Recombinant Protein Tumor Antigen Vaccine Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2009 | Pubmed ID: 19118058 Efficient in Vitro Expansion of JC Virus-specific CD8(+) T-cell Responses by JCV Peptide-stimulated Dendritic Cells from Patients with Progressive Multifocal Leukoencephalopathy Virology. Jan, 2009 | Pubmed ID: 19062062 Innate Immune Responses in Primary HIV-1 Infection Current Opinion in HIV and AIDS. Jan, 2008 | Pubmed ID: 19372942 KBMA Listeria Monocytogenes is an Effective Vector for DC-mediated Induction of Antitumor Immunity The Journal of Clinical Investigation. Dec, 2008 | Pubmed ID: 19033668 Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 MRNA-transfected Dendritic Cells Cancer Research. Nov, 2008 | Pubmed ID: 19010919 HIV-activated Human Plasmacytoid DCs Induce Tregs Through an Indoleamine 2,3-dioxygenase-dependent Mechanism The Journal of Clinical Investigation. Oct, 2008 | Pubmed ID: 18776940 Immunization of Malignant Melanoma Patients with Full-length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod As Vaccine Adjuvant Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18566444 The Anergic State in Sarcoidosis is Associated with Diminished Dendritic Cell Function Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18566441 Quantitative Effect of Suboptimal Codon Usage on Translational Efficiency of MRNA Encoding HIV-1 Gag in Intact T Cells PloS One. 2008 | Pubmed ID: 18523584 Lack of Functionally Active Melan-A(26-35)-specific T Cells in the Blood of HLA-A2+ Vitiligo Patients The Journal of Investigative Dermatology. Aug, 2008 | Pubmed ID: 18337837 Biology of Plasmacytoid Dendritic Cells and Natural Killer Cells in HIV-1 Infection Current Opinion in HIV and AIDS. May, 2007 | Pubmed ID: 19372886 Exploiting Dendritic Cells for Active Immunotherapy of Cancer and Chronic Infections Molecular Biotechnology. Jun, 2007 | Pubmed ID: 17914192 Expression of the Cancer/testis Antigen NY-ESO-1 in Primary and Metastatic Malignant Melanoma (MM)--correlation with Prognostic Factors Cancer Immunity. 2007 | Pubmed ID: 17625806 Armed and Ready: How Effector T Cells Deploy in Reactive Lymph Nodes to Modulate Immunity Nature Immunology. Jul, 2007 | Pubmed ID: 17579644 Pathways Utilized by Dendritic Cells for Binding, Uptake, Processing and Presentation of Antigens Derived from HIV-1 European Journal of Immunology. Jul, 2007 | Pubmed ID: 17534864 Vaccination with NY-ESO-1 Protein and CpG in Montanide Induces Integrated Antibody/Th1 Responses and CD8 T Cells Through Cross-priming Proceedings of the National Academy of Sciences of the United States of America. May, 2007 | Pubmed ID: 17517626 Harnessing the Immune System to Treat Cancer The Journal of Clinical Investigation. May, 2007 | Pubmed ID: 17476342 Clinical Relevance of Neutral Endopeptidase (NEP/CD10) in Melanoma Journal of Translational Medicine. 2007 | Pubmed ID: 17207277 The Apoptotic-cell Receptor CR3, but Not Alphavbeta5, is a Regulator of Human Dendritic-cell Immunostimulatory Function Blood. Aug, 2006 | Pubmed ID: 16614246 Expansion of HIV-specific CD4+ and CD8+ T Cells by Dendritic Cells Transfected with MRNA Encoding Cytoplasm- or Lysosome-targeted Nef Blood. Mar, 2006 | Pubmed ID: 16249391 Differentiation of Peripheral Blood Monocytes into Dendritic Cells Current Protocols in Immunology / Edited by John E. Coligan ... [et Al.]. Jul, 2005 | Pubmed ID: 18432951 Endocytosis of HIV-1 Activates Plasmacytoid Dendritic Cells Via Toll-like Receptor-viral RNA Interactions The Journal of Clinical Investigation. Nov, 2005 | Pubmed ID: 16224540 Combining Radiotherapy and Immunotherapy: a Revived Partnership International Journal of Radiation Oncology, Biology, Physics. Nov, 2005 | Pubmed ID: 16199306 Recent Advances in Dendritic Cell Biology Journal of Clinical Immunology. May, 2005 | Pubmed ID: 16118915 Recent Advances in Dendritic Cell Biology Journal of Clinical Immunology. Mar, 2005 | Pubmed ID: 15821885 Transmission and Accumulation of CTL Escape Variants Drive Negative Associations Between HIV Polymorphisms and HLA The Journal of Experimental Medicine. Mar, 2005 | Pubmed ID: 15781581 The Cancer-testis Antigens CT7 (MAGE-C1) and MAGE-A3/6 Are Commonly Expressed in Multiple Myeloma and Correlate with Plasma-cell Proliferation Blood. Jul, 2005 | Pubmed ID: 15761016 Plasmacytoid Dendritic Cells: Linking Innate and Adaptive Immunity Journal of Virology. Jan, 2005 | Pubmed ID: 15596797 Generation of Autologous Peptide- and Protein-pulsed Dendritic Cells for Patient-specific Immunotherapy Methods in Molecular Medicine. 2005 | Pubmed ID: 15585916 Exploiting Dendritic Cells for Active Immunotherapy of Cancer and Chronic Infection Methods in Molecular Medicine. 2005 | Pubmed ID: 15585909 CD8 Epitope Escape and Reversion in Acute HCV Infection The Journal of Experimental Medicine. Dec, 2004 | Pubmed ID: 15611288 Maturation Matters: Importance of Maturation for Antitumor Immunity of Dendritic Cell Vaccines Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2004 | Pubmed ID: 15365084 Manipulating Dendritic Cell Biology for the Active Immunotherapy of Cancer Blood. Oct, 2004 | Pubmed ID: 15231572 Danger Signals: a Time and Space Continuum Trends in Molecular Medicine. Jun, 2004 | Pubmed ID: 15177188 Lack of Phenotypic and Functional Impairment in Dendritic Cells from Chimpanzees Chronically Infected with Hepatitis C Virus Journal of Virology. Jun, 2004 | Pubmed ID: 15163708 DC-virus Interplay: a Double Edged Sword Seminars in Immunology. Jun, 2004 | Pubmed ID: 15130499 Human Immunodeficiency Virus Type 1 Activates Plasmacytoid Dendritic Cells and Concomitantly Induces the Bystander Maturation of Myeloid Dendritic Cells Journal of Virology. May, 2004 | Pubmed ID: 15113904 Dendritic Cells and the Promise of Therapeutic Vaccines for Human Immunodeficiency Virus (HIV)-1 Current HIV Research. Apr, 2003 | Pubmed ID: 15043203 Type I Interferons Promote Cross-priming: More Functions for Old Cytokines Nature Immunology. Oct, 2003 | Pubmed ID: 14515123 Against the Self: Dendritic Cells Versus Cancer APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Jul-Aug, 2003 | Pubmed ID: 12974782 Characterization of the MHC Class I Cross-presentation Pathway for Cell-associated Antigens by Human Dendritic Cells Blood. Dec, 2003 | Pubmed ID: 12933572 Dominant Effector Memory Characteristics, Capacity for Dynamic Adaptive Expansion, and Sex Bias in the Innate Valpha24 NKT Cell Compartment European Journal of Immunology. Mar, 2003 | Pubmed ID: 12616479 Immunotherapy for AIDS Virus Infections: Cautious Optimism for Cell-based Vaccine Nature Medicine. Jan, 2003 | Pubmed ID: 12514710 Activation of Influenza Virus-specific CD4+ and CD8+ T Cells: a New Role for Plasmacytoid Dendritic Cells in Adaptive Immunity Blood. May, 2003 | Pubmed ID: 12511409 A Clinical Grade Cocktail of Cytokines and PGE2 Results in Uniform Maturation of Human Monocyte-derived Dendritic Cells: Implications for Immunotherapy Vaccine. Dec, 2002 | Pubmed ID: 12477423 A Division of Labor: DC Subsets and HIV Receptor Diversity Nature Immunology. Oct, 2002 | Pubmed ID: 12352961 Dendritic Cell Amplification of HIV Type 1-specific CD8+ T Cell Responses in Exposed, Seronegative Heterosexual Women AIDS Research and Human Retroviruses. Jul, 2002 | Pubmed ID: 12167272 Activation of HIV-1 Specific CD4 and CD8 T Cells by Human Dendritic Cells: Roles for Cross-presentation and Non-infectious HIV-1 Virus AIDS (London, England). Jul, 2002 | Pubmed ID: 12131208 Selective Loss of Innate CD4(+) V Alpha 24 Natural Killer T Cells in Human Immunodeficiency Virus Infection Journal of Virology. Aug, 2002 | Pubmed ID: 12097565 Interactions Between Dead Cells and Dendritic Cells in the Induction of Antiviral CTL Responses Current Opinion in Immunology. Aug, 2002 | Pubmed ID: 12088682 Amplification of Low-frequency Antiviral CD8 T Cell Responses Using Autologous Dendritic Cells AIDS (London, England). Jan, 2002 | Pubmed ID: 11807300 Residual Viral Replication During Antiretroviral Therapy Boosts Human Immunodeficiency Virus Type 1-specific CD8+ T-cell Responses in Subjects Treated Early After Infection Journal of Virology. Jan, 2002 | Pubmed ID: 11739706 Активация и Измерение NLRP3 Inflammasome деятельности Использование IL-1β в человека моноцитов дендритные клетки Melissa V. Fernandez1, Elizabeth A. Miller2, Nina Bhardwaj3 1Department of Pathology, New York University School of Medicine, 2Division of Infectious Diseases, Department of Medicine, Mount Sinai Medical Center, 3Division of Hematology and Oncology, Hess Center for Science and Medicine, Mount Sinai Medical Center JoVE 51284 Immunology and Infection Подготовка опухолевый антиген нагруженных Зрелые дендритные клетки иммунотерапии Rachel Lubong Sabado1, Elizabeth Miller2, Meredith Spadaccia1, Isabelita Vengco1, Farah Hasan1, Nina Bhardwaj1 1Cancer Institute, NYU Langone Medical Center, 2Infectious Diseases, NYU Langone Medical Center JoVE 50085 Immunology and Infection
Активация и Измерение NLRP3 Inflammasome деятельности Использование IL-1β в человека моноцитов дендритные клетки Melissa V. Fernandez1, Elizabeth A. Miller2, Nina Bhardwaj3 1Department of Pathology, New York University School of Medicine, 2Division of Infectious Diseases, Department of Medicine, Mount Sinai Medical Center, 3Division of Hematology and Oncology, Hess Center for Science and Medicine, Mount Sinai Medical Center JoVE 51284 Immunology and Infection
Подготовка опухолевый антиген нагруженных Зрелые дендритные клетки иммунотерапии Rachel Lubong Sabado1, Elizabeth Miller2, Meredith Spadaccia1, Isabelita Vengco1, Farah Hasan1, Nina Bhardwaj1 1Cancer Institute, NYU Langone Medical Center, 2Infectious Diseases, NYU Langone Medical Center JoVE 50085 Immunology and Infection
