Oleksandr Platoshyn Neuroregeneration Laboratory, Department of Anesthesiology University of California, San Diego Biography Publications Institution JoVE Articles Oleksandr Platoshyn has not added a biography. If you are Oleksandr Platoshyn and would like to personalize this page please email our Author Liaison for assistance. Publications Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs Neuron. May, 2016 | Pubmed ID: 27112497 Thoracic 9 Spinal Transection-Induced Model of Muscle Spasticity in the Rat: A Systematic Electrophysiological and Histopathological Characterization PloS One. 2015 | Pubmed ID: 26713446 Vinculin Directly Binds Zonula Occludens-1 and is Essential for Stabilizing Connexin-43-containing Gap Junctions in Cardiac Myocytes Journal of Cell Science. Mar, 2014 | Pubmed ID: 24413171 Amelioration of Motor/sensory Dysfunction and Spasticity in a Rat Model of Acute Lumbar Spinal Cord Injury by Human Neural Stem Cell Transplantation Stem Cell Research & Therapy. May, 2013 | Pubmed ID: 23710605 ALS-linked TDP-43 Mutations Produce Aberrant RNA Splicing and Adult-onset Motor Neuron Disease Without Aggregation or Loss of Nuclear TDP-43 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23382207 Combinational Spinal GAD65 Gene Delivery and Systemic GABA-mimetic Treatment for Modulation of Spasticity PloS One. 2012 | Pubmed ID: 22291989 Functional Ion Channels in Human Pulmonary Artery Smooth Muscle Cells: Voltage-dependent Cation Channels Pulmonary Circulation. Jan, 2011 | Pubmed ID: 21927714 Tetramerization Domain Mutations in KCNA5 Affect Channel Kinetics and Cause Abnormal Trafficking Patterns American Journal of Physiology. Cell Physiology. Mar, 2010 | Pubmed ID: 20018952 Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells Annals of the New York Academy of Sciences. Oct, 2009 | Pubmed ID: 19845612 Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases PloS One. Sep, 2008 | Pubmed ID: 18769546 P75 Neurotrophin Receptor Regulates Agonist-induced Pulmonary Vasoconstriction American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2008 | Pubmed ID: 18689502 Downregulation of Connexin40 is Associated with Coronary Endothelial Cell Dysfunction in Streptozotocin-induced Diabetic Mice American Journal of Physiology. Cell Physiology. Jul, 2008 | Pubmed ID: 18463230 Characterization of Agonist-induced Vasoconstriction in Mouse Pulmonary Artery American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2008 | Pubmed ID: 17982012 Hypoxia Divergently Regulates Production of Reactive Oxygen Species in Human Pulmonary and Coronary Artery Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2007 | Pubmed ID: 17693484 Functional Characterization of Voltage-gated K+ Channels in Mouse Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Sep, 2007 | Pubmed ID: 17581857 Heterogeneity of Hypoxia-mediated Decrease in I(K(V)) and Increase in [Ca2+](cyt) in Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2007 | Pubmed ID: 17526598 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Functionality is Dependent on Coatomer Protein I (COPI) Biology of the Cell. Aug, 2007 | Pubmed ID: 17388782 Dynamics of Alpha-synuclein Aggregation and Inhibition of Pore-like Oligomer Development by Beta-synuclein The FEBS Journal. Apr, 2007 | Pubmed ID: 17381514 Function of Kv1.5 Channels and Genetic Variations of KCNA5 in Patients with Idiopathic Pulmonary Arterial Hypertension American Journal of Physiology. Cell Physiology. May, 2007 | Pubmed ID: 17267549 Thiol Oxidation Causes Pulmonary Vasodilation by Activating K+ Channels and Inhibiting Store-operated Ca2+ Channels American Journal of Physiology. Lung Cellular and Molecular Physiology. Mar, 2007 | Pubmed ID: 17098807 Bone Morphogenetic Protein-2 Upregulates Expression and Function of Voltage-gated K+ Channels in Human Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2006 | Pubmed ID: 16815889 TRPC1 Functions As a Store-operated Ca2+ Channel in Intestinal Epithelial Cells and Regulates Early Mucosal Restitution After Wounding American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2006 | Pubmed ID: 16282360 Acute Hypoxia Selectively Inhibits KCNA5 Channels in Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Mar, 2006 | Pubmed ID: 16236819 Divergent Effects of BMP-2 on Gene Expression in Pulmonary Artery Smooth Muscle Cells from Normal Subjects and Patients with Idiopathic Pulmonary Arterial Hypertension Experimental Lung Research. Oct, 2005 | Pubmed ID: 16368652 Long QT Syndrome-associated I593R Mutation in HERG Potassium Channel Activates ER Stress Pathways Cell Biochemistry and Biophysics. 2005 | Pubmed ID: 16244363 Identification of Functional Voltage-gated Na(+) Channels in Cultured Human Pulmonary Artery Smooth Muscle Cells Pflugers Archiv : European Journal of Physiology. Nov, 2005 | Pubmed ID: 16052353 Postnatal Isl1+ Cardioblasts Enter Fully Differentiated Cardiomyocyte Lineages Nature. Feb, 2005 | Pubmed ID: 15703750 Enhanced Expression of Transient Receptor Potential Channels in Idiopathic Pulmonary Arterial Hypertension Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15358862 Overexpression of TRPC1 Enhances Pulmonary Vasoconstriction Induced by Capacitative Ca2+ Entry American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2004 | Pubmed ID: 15220115 Overexpression of Human KCNA5 Increases IK V and Enhances Apoptosis American Journal of Physiology. Cell Physiology. Sep, 2004 | Pubmed ID: 15140747 Diversity of Voltage-dependent K+ Channels in Human Pulmonary Artery Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2004 | Pubmed ID: 15047570 Hypoxia Increases AP-1 Binding Activity by Enhancing Capacitative Ca2+ Entry in Human Pulmonary Artery Endothelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Dec, 2003 | Pubmed ID: 12909593 Bone Morphogenetic Proteins Induce Apoptosis in Human Pulmonary Vascular Smooth Muscle Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2003 | Pubmed ID: 12740218 Apoptosis Repressor with Caspase Domain Inhibits Cardiomyocyte Apoptosis by Reducing K+ Currents American Journal of Physiology. Cell Physiology. Jun, 2003 | Pubmed ID: 12734105 PDGF Stimulates Pulmonary Vascular Smooth Muscle Cell Proliferation by Upregulating TRPC6 Expression American Journal of Physiology. Cell Physiology. Feb, 2003 | Pubmed ID: 12529250 Cytochrome C Activates K+ Channels Before Inducing Apoptosis American Journal of Physiology. Cell Physiology. Oct, 2002 | Pubmed ID: 12225992 Inhibition of Endogenous TRP1 Decreases Capacitative Ca2+ Entry and Attenuates Pulmonary Artery Smooth Muscle Cell Proliferation American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2002 | Pubmed ID: 12060571 Role of Capacitative Ca2+ Entry in Bronchial Contraction and Remodeling Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2002 | Pubmed ID: 11896026 Activation of K(+) Channels and Increased Migration of Differentiated Intestinal Epithelial Cells After Wounding American Journal of Physiology. Cell Physiology. Apr, 2002 | Pubmed ID: 11880277 Nitric Oxide Induces Apoptosis by Activating K+ Channels in Pulmonary Vascular Smooth Muscle Cells American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2002 | Pubmed ID: 11748062 Yetişkin Farelerde Subpial Adeno-ilişkili Virüs 9 (AAV9) Vektör Teslimatı Takahiro Tadokoro1, Atsushi Miyanohara1, Michael Navarro1, Kota Kamizato1, Stefan Juhas2, Jana Juhasova2, Silvia Marsala1, Oleksandr Platoshyn1, Erik Curtis3, Brandon Gabel3, Joseph Ciacci3, Nada Lukacova4, Katarina Bimbova4, Martin Marsala1,4 1Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, 2Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 3Department of Neurosurgery, University of California, San Diego, 4Institute of Neurobiology, Slovak Academy of Sciences JoVE 55770 Neuroscience
Yetişkin Farelerde Subpial Adeno-ilişkili Virüs 9 (AAV9) Vektör Teslimatı Takahiro Tadokoro1, Atsushi Miyanohara1, Michael Navarro1, Kota Kamizato1, Stefan Juhas2, Jana Juhasova2, Silvia Marsala1, Oleksandr Platoshyn1, Erik Curtis3, Brandon Gabel3, Joseph Ciacci3, Nada Lukacova4, Katarina Bimbova4, Martin Marsala1,4 1Neuroregeneration Laboratory, Department of Anesthesiology, University of California, San Diego, 2Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 3Department of Neurosurgery, University of California, San Diego, 4Institute of Neurobiology, Slovak Academy of Sciences JoVE 55770 Neuroscience
