Articles by Ozge Kurtulus in JoVE
Microfabrication of Nanoporous Gold Patterns for Cell-material Interaction Studies Pallavi Daggumati1, Ozge Kurtulus2, Christopher Abbott Reece Chapman3, Damla Dimlioglu1, Erkin Seker1 1Department of Electrical and Computer Engineering, University of California, Davis, 2Department of Chemical Engineering and Materials Science, University of California, Davis, 3Department of Biomedical Engineering, University of California, Davis We report on techniques to micropattern nanoporous gold thin films via stencil printing and photolithography, as well as methods to culture cells on the microfabricated patterns. In addition, we describe image analysis methods to characterize morphology of the material and the cultured cells using scanning electron and fluorescence microscopy techniques.
Other articles by Ozge Kurtulus on PubMed
Recent Progress in SERS Biosensing Physical Chemistry Chemical Physics : PCCP. Jun, 2011 | Pubmed ID: 21509385 This perspective gives an overview of recent developments in surface-enhanced Raman scattering (SERS) for biosensing. We focus this review on SERS papers published in the last 10 years and to specific applications of detecting biological analytes. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids, lipids, peptides, and proteins, as well as for in vivo and cellular sensing. Current SERS substrate technologies along with a series of advancements in surface chemistry, sample preparation, intrinsic/extrinsic signal transduction schemes, and tip-enhanced Raman spectroscopy are discussed. The progress covered herein shows great promise for widespread adoption of SERS biosensing.
Nanotopography Effects on Astrocyte Attachment to Nanoporous Gold Surfaces Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2012 | Pubmed ID: 23367434 Nanoporous gold, synthesized by a self-assembly process, is a new biomaterial with desirable attributes, including tunable nanotopography, drug delivery potential, electrical conductivity, and compatibility with conventional microfabrication techniques. This study reports on the effect of nanotopography in guiding cellular attachment on nanoporous gold surfaces. While the changes in topography do not affect adherent cell density, average cell area displays a non-monotonic dependence on nanotopography.