Patricia Sancho

Publications

• Microenvironmental HCAP-18/LL-37 Promotes Pancreatic Ductal Adenocarcinoma by Activating Its Cancer Stem Cell Compartment
  Gut. Apr, 2015  |   Pubmed ID: 25841238
• A Mesenchymal-like Phenotype and Expression of CD44 Predict Lack of Apoptotic Response to Sorafenib in Liver Tumor Cells
  International Journal of Cancer. Journal International Du Cancer. Feb, 2015  |   Pubmed ID: 25053293
• Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer Via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice
  Gastroenterology. Nov, 2014  |   Pubmed ID: 25127677
• The NADPH Oxidase NOX4 Inhibits Hepatocyte Proliferation and Liver Cancer Progression
  Free Radical Biology & Medicine. Apr, 2014  |   Pubmed ID: 24509161
• [Cost-consequence Analysis of Respiratory Preventive Intervention Among Institutionalized Older People: Randomized Controlled Trial]
  Revista Española De Geriatría Y Gerontología. Sep-Oct, 2014  |   Pubmed ID: 24417971
• TGF-beta Signaling in Cancer Treatment
  Current Pharmaceutical Design. 2014  |   Pubmed ID: 23944366
• Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells
  PloS One. 2013  |   Pubmed ID: 24204632
• Overactivation of the TGF-β Pathway Confers a Mesenchymal-like Phenotype and CXCR4-dependent Migratory Properties to Liver Tumor Cells
  Hepatology (Baltimore, Md.). Dec, 2013  |   Pubmed ID: 23813475
• ROS Production is Essential for the Apoptotic Function of E2F1 in Pheochromocytoma and Neuroblastoma Cell Lines
  PloS One. 2012  |   Pubmed ID: 23251571
• Coping Strategies: Gender Differences and Development Throughout Life Span
  The Spanish Journal of Psychology. Nov, 2012  |   Pubmed ID: 23156917
• NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death During Liver Fibrosis Development
  PloS One. 2012  |   Pubmed ID: 23049784
• Predicting Perceived Health in Angolan Elderly: the Moderator Effect of Being Oldest Old
  Archives of Gerontology and Geriatrics. Nov-Dec, 2012  |   Pubmed ID: 22770711
• Protein-tyrosine Phosphatase 1B (PTP1B) Deficiency Confers Resistance to Transforming Growth Factor-β (TGF-β)-induced Suppressor Effects in Hepatocytes
  The Journal of Biological Chemistry. May, 2012  |   Pubmed ID: 22427664
• Resilience and Coping As Predictors of General Well-being in the Elderly: a Structural Equation Modeling Approach
  Aging & Mental Health. 2012  |   Pubmed ID: 22292552
• Lack of Amino Acids in Mouse Hepatocytes in Culture Induces the Selection of Preneoplastic Cells
  Cellular Signalling. Jan, 2012  |   Pubmed ID: 21964063
• Sorafenib Sensitizes Hepatocellular Carcinoma Cells to Physiological Apoptotic Stimuli
  Journal of Cellular Physiology. Apr, 2012  |   Pubmed ID: 21604268
• Reciprocal Regulation of NADPH Oxidases and the Cyclooxygenase-2 Pathway
  Free Radical Biology & Medicine. Nov, 2011  |   Pubmed ID: 21907277
• The Tyrphostin AG1478 Inhibits Proliferation and Induces Death of Liver Tumor Cells Through EGF Receptor-dependent and Independent Mechanisms
  Biochemical Pharmacology. Dec, 2011  |   Pubmed ID: 21864510
• The NADPH Oxidase Inhibitor VAS2870 Impairs Cell Growth and Enhances TGF-β-induced Apoptosis of Liver Tumor Cells
  Biochemical Pharmacology. Apr, 2011  |   Pubmed ID: 21276422
• Dissecting the Effect of Targeting the Epidermal Growth Factor Receptor on TGF-β-induced-apoptosis in Human Hepatocellular Carcinoma Cells
  Journal of Hepatology. Aug, 2011  |   Pubmed ID: 21147185
• Snail1 Suppresses TGF-beta-induced Apoptosis and is Sufficient to Trigger EMT in Hepatocytes
  Journal of Cell Science. Oct, 2010  |   Pubmed ID: 20930141
• NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells Through Up-regulation of the Epidermal Growth Factor Receptor Pathway
  The Journal of Biological Chemistry. Aug, 2010  |   Pubmed ID: 20525691
• Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF-{beta}-induced Cell Death Through Impairing Up-regulation of the NADPH Oxidase NOX4
  Cancer Research. Oct, 2009  |   Pubmed ID: 19773433
• Role of CXCR4/SDF-1 Alpha in the Migratory Phenotype of Hepatoma Cells That Have Undergone Epithelial-mesenchymal Transition in Response to the Transforming Growth Factor-beta
  Cellular Signalling. Nov, 2009  |   Pubmed ID: 19586611
• Caspase-independent Type III Programmed Cell Death in Chronic Lymphocytic Leukemia: the Key Role of the F-actin Cytoskeleton
  Haematologica. Apr, 2009  |   Pubmed ID: 19278964
• The Inhibition of the Epidermal Growth Factor (EGF) Pathway Enhances TGF-beta-induced Apoptosis in Rat Hepatoma Cells Through Inducing Oxidative Stress Coincident with a Change in the Expression Pattern of the NADPH Oxidases (NOX) Isoforms
  Biochimica Et Biophysica Acta. Feb, 2009  |   Pubmed ID: 18848961
• Upregulation of the NADPH Oxidase NOX4 by TGF-beta in Hepatocytes is Required for Its Pro-apoptotic Activity
  Journal of Hepatology. Dec, 2008  |   Pubmed ID: 18845355
• Inhibition of the EGF Receptor Blocks Autocrine Growth and Increases the Cytotoxic Effects of Doxorubicin in Rat Hepatoma Cells: Role of Reactive Oxygen Species Production and Glutathione Depletion
  Biochemical Pharmacology. May, 2008  |   Pubmed ID: 18371937
• Drp1 Mediates Caspase-independent Type III Cell Death in Normal and Leukemic Cells
  Molecular and Cellular Biology. Oct, 2007  |   Pubmed ID: 17682056
• Pharmacological Inhibitors of Extracellular Signal-regulated Protein Kinases Attenuate the Apoptotic Action of Cisplatin in Human Myeloid Leukemia Cells Via Glutathione-independent Reduction in Intracellular Drug Accumulation
  Biochimica Et Biophysica Acta. Apr, 2005  |   Pubmed ID: 15843040
• Pharmacologic Inhibitors of PI3K/Akt Potentiate the Apoptotic Action of the Antileukemic Drug Arsenic Trioxide Via Glutathione Depletion and Increased Peroxide Accumulation in Myeloid Leukemia Cells
  Blood. May, 2005  |   Pubmed ID: 15665116
• 12-O-tetradecanoylphorbol-13-acetate May Both Potentiate and Decrease the Generation of Apoptosis by the Antileukemic Agent Arsenic Trioxide in Human Promonocytic Cells. Regulation by Extracellular Signal-regulated Protein Kinases and Glutathione
  The Journal of Biological Chemistry. Jan, 2004  |   Pubmed ID: 14610070
• Differential Effects of Catalase on Apoptosis Induction in Human Promonocytic Cells. Relationships with Heat-shock Protein Expression
  Molecular Pharmacology. Mar, 2003  |   Pubmed ID: 12606765