Patricia Sancho Stem Cells & Cancer Group, Molecular Pathology Program Spanish National Cancer Research Center Biography Publications Institution JoVE Articles Patricia Sancho has not added a biography. If you are Patricia Sancho and would like to personalize this page please email our Author Liaison for assistance. Publications Microenvironmental HCAP-18/LL-37 Promotes Pancreatic Ductal Adenocarcinoma by Activating Its Cancer Stem Cell Compartment Gut. Apr, 2015 | Pubmed ID: 25841238 A Mesenchymal-like Phenotype and Expression of CD44 Predict Lack of Apoptotic Response to Sorafenib in Liver Tumor Cells International Journal of Cancer. Journal International Du Cancer. Feb, 2015 | Pubmed ID: 25053293 Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer Via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice Gastroenterology. Nov, 2014 | Pubmed ID: 25127677 The NADPH Oxidase NOX4 Inhibits Hepatocyte Proliferation and Liver Cancer Progression Free Radical Biology & Medicine. Apr, 2014 | Pubmed ID: 24509161 [Cost-consequence Analysis of Respiratory Preventive Intervention Among Institutionalized Older People: Randomized Controlled Trial] Revista Española De Geriatría Y Gerontología. Sep-Oct, 2014 | Pubmed ID: 24417971 TGF-beta Signaling in Cancer Treatment Current Pharmaceutical Design. 2014 | Pubmed ID: 23944366 Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells PloS One. 2013 | Pubmed ID: 24204632 Overactivation of the TGF-β Pathway Confers a Mesenchymal-like Phenotype and CXCR4-dependent Migratory Properties to Liver Tumor Cells Hepatology (Baltimore, Md.). Dec, 2013 | Pubmed ID: 23813475 ROS Production is Essential for the Apoptotic Function of E2F1 in Pheochromocytoma and Neuroblastoma Cell Lines PloS One. 2012 | Pubmed ID: 23251571 Coping Strategies: Gender Differences and Development Throughout Life Span The Spanish Journal of Psychology. Nov, 2012 | Pubmed ID: 23156917 NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death During Liver Fibrosis Development PloS One. 2012 | Pubmed ID: 23049784 Predicting Perceived Health in Angolan Elderly: the Moderator Effect of Being Oldest Old Archives of Gerontology and Geriatrics. Nov-Dec, 2012 | Pubmed ID: 22770711 Protein-tyrosine Phosphatase 1B (PTP1B) Deficiency Confers Resistance to Transforming Growth Factor-β (TGF-β)-induced Suppressor Effects in Hepatocytes The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22427664 Resilience and Coping As Predictors of General Well-being in the Elderly: a Structural Equation Modeling Approach Aging & Mental Health. 2012 | Pubmed ID: 22292552 Lack of Amino Acids in Mouse Hepatocytes in Culture Induces the Selection of Preneoplastic Cells Cellular Signalling. Jan, 2012 | Pubmed ID: 21964063 Sorafenib Sensitizes Hepatocellular Carcinoma Cells to Physiological Apoptotic Stimuli Journal of Cellular Physiology. Apr, 2012 | Pubmed ID: 21604268 Reciprocal Regulation of NADPH Oxidases and the Cyclooxygenase-2 Pathway Free Radical Biology & Medicine. Nov, 2011 | Pubmed ID: 21907277 The Tyrphostin AG1478 Inhibits Proliferation and Induces Death of Liver Tumor Cells Through EGF Receptor-dependent and Independent Mechanisms Biochemical Pharmacology. Dec, 2011 | Pubmed ID: 21864510 The NADPH Oxidase Inhibitor VAS2870 Impairs Cell Growth and Enhances TGF-β-induced Apoptosis of Liver Tumor Cells Biochemical Pharmacology. Apr, 2011 | Pubmed ID: 21276422 Dissecting the Effect of Targeting the Epidermal Growth Factor Receptor on TGF-β-induced-apoptosis in Human Hepatocellular Carcinoma Cells Journal of Hepatology. Aug, 2011 | Pubmed ID: 21147185 Snail1 Suppresses TGF-beta-induced Apoptosis and is Sufficient to Trigger EMT in Hepatocytes Journal of Cell Science. Oct, 2010 | Pubmed ID: 20930141 NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells Through Up-regulation of the Epidermal Growth Factor Receptor Pathway The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20525691 Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF-{beta}-induced Cell Death Through Impairing Up-regulation of the NADPH Oxidase NOX4 Cancer Research. Oct, 2009 | Pubmed ID: 19773433 Role of CXCR4/SDF-1 Alpha in the Migratory Phenotype of Hepatoma Cells That Have Undergone Epithelial-mesenchymal Transition in Response to the Transforming Growth Factor-beta Cellular Signalling. Nov, 2009 | Pubmed ID: 19586611 Caspase-independent Type III Programmed Cell Death in Chronic Lymphocytic Leukemia: the Key Role of the F-actin Cytoskeleton Haematologica. Apr, 2009 | Pubmed ID: 19278964 The Inhibition of the Epidermal Growth Factor (EGF) Pathway Enhances TGF-beta-induced Apoptosis in Rat Hepatoma Cells Through Inducing Oxidative Stress Coincident with a Change in the Expression Pattern of the NADPH Oxidases (NOX) Isoforms Biochimica Et Biophysica Acta. Feb, 2009 | Pubmed ID: 18848961 Upregulation of the NADPH Oxidase NOX4 by TGF-beta in Hepatocytes is Required for Its Pro-apoptotic Activity Journal of Hepatology. Dec, 2008 | Pubmed ID: 18845355 Inhibition of the EGF Receptor Blocks Autocrine Growth and Increases the Cytotoxic Effects of Doxorubicin in Rat Hepatoma Cells: Role of Reactive Oxygen Species Production and Glutathione Depletion Biochemical Pharmacology. May, 2008 | Pubmed ID: 18371937 Drp1 Mediates Caspase-independent Type III Cell Death in Normal and Leukemic Cells Molecular and Cellular Biology. Oct, 2007 | Pubmed ID: 17682056 Pharmacological Inhibitors of Extracellular Signal-regulated Protein Kinases Attenuate the Apoptotic Action of Cisplatin in Human Myeloid Leukemia Cells Via Glutathione-independent Reduction in Intracellular Drug Accumulation Biochimica Et Biophysica Acta. Apr, 2005 | Pubmed ID: 15843040 Pharmacologic Inhibitors of PI3K/Akt Potentiate the Apoptotic Action of the Antileukemic Drug Arsenic Trioxide Via Glutathione Depletion and Increased Peroxide Accumulation in Myeloid Leukemia Cells Blood. May, 2005 | Pubmed ID: 15665116 12-O-tetradecanoylphorbol-13-acetate May Both Potentiate and Decrease the Generation of Apoptosis by the Antileukemic Agent Arsenic Trioxide in Human Promonocytic Cells. Regulation by Extracellular Signal-regulated Protein Kinases and Glutathione The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14610070 Differential Effects of Catalase on Apoptosis Induction in Human Promonocytic Cells. Relationships with Heat-shock Protein Expression Molecular Pharmacology. Mar, 2003 | Pubmed ID: 12606765 دراسة سرطان البنكرياس الجذعية خصائص الخلايا لتطوير استراتيجيات علاجية جديدة Enza Lonardo1,2, Michele Cioffi1, Patricia Sancho1,3, Shanthini Crusz3, Christopher Heeschen1,3 1Stem Cells & Cancer Group, Molecular Pathology Program, Spanish National Cancer Research Center, 2Institute for Research in Biomedicine (IRB Barcelona), 3Center for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London Medicine
دراسة سرطان البنكرياس الجذعية خصائص الخلايا لتطوير استراتيجيات علاجية جديدة Enza Lonardo1,2, Michele Cioffi1, Patricia Sancho1,3, Shanthini Crusz3, Christopher Heeschen1,3 1Stem Cells & Cancer Group, Molecular Pathology Program, Spanish National Cancer Research Center, 2Institute for Research in Biomedicine (IRB Barcelona), 3Center for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London Medicine