Patrick J. M. Murphy

Publications

• Regulation of the Dynamics of Hsp90 Action on the Glucocorticoid Receptor by Acetylation/deacetylation of the Chaperone
  The Journal of Biological Chemistry. Oct, 2005  |   Pubmed ID: 16087666
• HDAC6 Regulates Hsp90 Acetylation and Chaperone-dependent Activation of Glucocorticoid Receptor
  Molecular Cell. May, 2005  |   Pubmed ID: 15916966
• Evidence for Glucocorticoid Receptor Transport on Microtubules by Dynein
  The Journal of Biological Chemistry. Dec, 2004  |   Pubmed ID: 15485845
• Role of Molecular Chaperones in Steroid Receptor Action
  Essays in Biochemistry. 2004  |   Pubmed ID: 15242338
• The Role of Hsp90 in Heme-dependent Activation of Apo-neuronal Nitric-oxide Synthase
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15155759
• Pifithrin-alpha Inhibits P53 Signaling After Interaction of the Tumor Suppressor Protein with Hsp90 and Its Nuclear Translocation
  The Journal of Biological Chemistry. Jul, 2004  |   Pubmed ID: 15145929
• The Hsp90 Cochaperone P23 is the Limiting Component of the Multiprotein Hsp90/hsp70-based Chaperone System in Vivo Where It Acts to Stabilize the Client Protein: Hsp90 Complex
  The Journal of Biological Chemistry. Dec, 2003  |   Pubmed ID: 14507910
• Visualization and Mechanism of Assembly of a Glucocorticoid Receptor.Hsp70 Complex That is Primed for Subsequent Hsp90-dependent Opening of the Steroid Binding Cleft
  The Journal of Biological Chemistry. Sep, 2003  |   Pubmed ID: 12807878
• Binding of Hsp90-associated Immunophilins to Cytoplasmic Dynein: Direct Binding and in Vivo Evidence That the Peptidylprolyl Isomerase Domain is a Dynein Interaction Domain
  Biochemistry. Nov, 2002  |   Pubmed ID: 12427021
• Mutations at Positions 547-553 of Rat Glucocorticoid Receptors Reveal That Hsp90 Binding Requires the Presence, but Not Defined Composition, of a Seven-amino Acid Sequence at the Amino Terminus of the Ligand Binding Domain
  The Journal of Biological Chemistry. Sep, 2002  |   Pubmed ID: 12145311
• Hsp90 is Required for Heme Binding and Activation of Apo-neuronal Nitric-oxide Synthase: Geldanamycin-mediated Oxidant Generation is Unrelated to Any Action of Hsp90
  The Journal of Biological Chemistry. Jun, 2002  |   Pubmed ID: 11923316