Paul J. Zhang Department of Pathology and Lab Medicine, Perelman School of Medicine University of Pennsylvania Biography Publications Institution JoVE Articles Paul J. Zhang has not added a biography. If you are Paul J. Zhang and would like to personalize this page please email our Author Liaison for assistance. Publications Retroperitoneal Dedifferentiated Liposarcoma Lacking MDM2 Amplification in a Patient with a Germ Line CHEK2 Mutation Virchows Archiv : an International Journal of Pathology. Mar, 2014 | Pubmed ID: 24595525 TTF-1 and Napsin-A Are Expressed in a Subset of Cholangiocarcinomas Arising from the Gallbladder and Hepatic Ducts: Continued Caveats for Utilization of Immunohistochemistry Panels The American Journal of Surgical Pathology. Feb, 2014 | Pubmed ID: 24418856 Expression of Notch Signaling Components in Cutaneous Foreign Body and Sarcoidal Granulomas and Fusing Macrophages The American Journal of Dermatopathology. Jan, 2014 | Pubmed ID: 24394305 Proximal-type Epithelioid Sarcoma of the Head and Neck (HN): A Study with Immunohistochemical and Molecular Analysis of SMARCB1 Journal of Clinical & Experimental Oncology. 2013 | Pubmed ID: 24308011 Hypoxia-inducible Factors: Mediators of Cancer Progression; Prognostic and Therapeutic Targets in Soft Tissue Sarcomas Cancers. 2013 | Pubmed ID: 24216979 Fibroblast Activation Protein Expression by Stromal Cells and Tumor-associated Macrophages in Human Breast Cancer Human Pathology. Nov, 2013 | Pubmed ID: 24074532 E-Cadherin Is Expressed by Mono- and Multinucleated Histiocytes in Cutaneous Sarcoidal and Foreign Body Granulomas The American Journal of Dermatopathology. May, 2013 | Pubmed ID: 23719484 Melanocytic Tumors Express Connexin 43 but Not 26: Immunohistochemical Analysis With Potential Significance in Melanocytic Oncogenesis The American Journal of Dermatopathology. Jan, 2013 | Pubmed ID: 23344009 Sirtuin 1 (SIRT1): a Potential Immunohistochemical Marker and Therapeutic Target in Soft Tissue Neoplasms with Myoid Differentiation Human Pathology. Jun, 2013 | Pubmed ID: 23332867 Intraosseous Hibernoma: a Potential Mimic of Metastatic Carcinoma Annals of Diagnostic Pathology. Apr, 2013 | Pubmed ID: 22884657 MITF Accurately Highlights Epidermal Melanocytes in Atypical Intraepidermal Melanocytic Proliferations The American Journal of Dermatopathology. Feb, 2013 | Pubmed ID: 22668579 Ectopic Functioning Adrenocortical Oncocytic Adenoma (oncocytoma) with Myelolipoma Causing Virilization Case Reports in Pathology. 2012 | Pubmed ID: 23094172 Cardiac Epithelioid PEComa: Report of Two Cases and Review of the Literature Case Reports in Medicine. 2012 | Pubmed ID: 22973317 Clear Cell Sarcoma: a Case Report with Radiological and Pathological Features of an Atypical Case Case Reports in Oncology. May, 2012 | Pubmed ID: 22949909 Malignant Mixed Mullerian Tumor: an Immunohistochemical Study Pathology Research International. 2012 | Pubmed ID: 22848863 Aberrant Connexin 43 and 26 Expression in Cervical Dysplasia Analytical and Quantitative Cytology and Histology / the International Academy of Cytology [and] American Society of Cytology. Feb, 2012 | Pubmed ID: 22590817 CDX2 Expression in Columnar Cell Variant of Papillary Thyroid Carcinoma American Journal of Clinical Pathology. May, 2012 | Pubmed ID: 22523209 P53 in Pure Epithelioid PEComa: an Immunohistochemistry Study and Gene Mutation Analysis International Journal of Surgical Pathology. Apr, 2012 | Pubmed ID: 22459898 Mesothelin, a Novel Immunotherapy Target for Triple Negative Breast Cancer Breast Cancer Research and Treatment. Jun, 2012 | Pubmed ID: 22418702 Lymphatic Invasion is Independently Prognostic of Metastasis in Primary Cutaneous Melanoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2012 | Pubmed ID: 22096024 The Extent of Retraction Clefts Correlates with Lymphatic Vessel Density and VEGF-C Expression and Predicts Nodal Metastasis and Poor Prognosis in Early-stage Breast Carcinoma Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2012 | Pubmed ID: 22020194 MUM-1 Expression Differentiates Tumors in the PEComa Family from Clear Cell Sarcoma and Melanoma International Journal of Surgical Pathology. Feb, 2012 | Pubmed ID: 21903680 Diagnosis and Endoscopic Management of Sinonasal Schwannomas ORL; Journal for Oto-rhino-laryngology and Its Related Specialties. 2011 | Pubmed ID: 21986025 Tracheobronchopathia Osteochondroplastica Presenting As a Single Dominant Tracheal Mass Annals of Diagnostic Pathology. Dec, 2011 | Pubmed ID: 21778098 Adult Urinary Bladder Tumors with Rhabdomyosarcomatous Differentiation: Clinical, Pathological and Immunohistochemical Studies Diagnostic Pathology. 2011 | Pubmed ID: 21762516 Connexin43 Expression Increases in the Epithelium and Stroma Along the Colonic Neoplastic Progression Pathway: Implications for Its Oncogenic Role Gastroenterology Research and Practice. 2011 | Pubmed ID: 21754925 Connexin 43 is a Potential Prognostic Biomarker for Ewing Sarcoma/primitive Neuroectodermal Tumor Sarcoma. 2011 | Pubmed ID: 21647307 Fluorescent in Situ Hybridization of a Skin Biopsy: an Adjunctive Tool to Support a Diagnosis of Graft-versus-host Disease Journal of the American Academy of Dermatology. Jun, 2011 | Pubmed ID: 21571154 The Significance of HER-2/neu Receptor Positivity and Immunophenotype in Ductal Carcinoma in Situ with Early Invasive Disease Journal of Surgical Oncology. Oct, 2011 | Pubmed ID: 21557226 High Lymphatic Vessel Density and Lymphatic Invasion Underlie the Adverse Prognostic Effect of Radial Growth Phase Regression in Melanoma The American Journal of Surgical Pathology. Feb, 2011 | Pubmed ID: 21263244 TFE3 Expression in Tumors of the Microphthalmia-associated Transcription Factor (MiTF) Family International Journal of Surgical Pathology. Feb, 2011 | Pubmed ID: 20164056 Invasive Ductal Carcinomas of the Breast Showing Partial Reversed Cell Polarity Are Associated with Lymphatic Tumor Spread and May Represent Part of a Spectrum of Invasive Micropapillary Carcinoma The American Journal of Surgical Pathology. Nov, 2010 | Pubmed ID: 20975342 Role for Trauma in Inducing Pencil "lead" Granuloma in the Skin Journal of the American Academy of Dermatology. Jun, 2010 | Pubmed ID: 20466188 Analysis of HIF-1alpha and Its Regulator, PHD2, in Retroperitoneal Sarcomas: Clinico-pathologic Implications Cancer Biology & Therapy. Feb, 2010 | Pubmed ID: 20026900 Hemangiomas of the Brachial Plexus: a Case Series Neurosurgery. Oct, 2009 | Pubmed ID: 19927066 IMP-3 is Differentially Expressed in Normal and Neoplastic Lymphoid Tissue Human Pathology. Dec, 2009 | Pubmed ID: 19698973 Thyroid Transcription Factor 1 Expression in Sellar Tumors: a Histogenetic Marker? Journal of Neuropathology and Experimental Neurology. May, 2009 | Pubmed ID: 19525896 Thyroid Transcription Factor-1 Expression in Normal Gynecologic Tissues and Its Potential Significance International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Jul, 2009 | Pubmed ID: 19483637 HER-2/neu Overexpression As a Predictor for the Transition from in Situ to Invasive Breast Cancer Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. May, 2009 | Pubmed ID: 19383888 TTF-1 Expression in Ovarian and Uterine Epithelial Neoplasia and Its Potential Significance, an Immunohistochemical Assessment with Multiple Monoclonal Antibodies and Different Secondary Detection Systems International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Jan, 2009 | Pubmed ID: 19047914 The Presence of Micropapillary Features and Retraction Artifact in Core Needle Biopsy Material Predicts Lymph Node Metastasis in Breast Carcinoma The American Journal of Surgical Pathology. Feb, 2009 | Pubmed ID: 18987549 Embryonal and Alveolar Rhabdomyosarcoma of Parameningeal Sites in Adults: a Report of 13 Cases International Journal of Surgical Pathology. Feb, 2009 | Pubmed ID: 18945709 ALK Expression in Rhabdomyosarcomas: Correlation with Histologic Subtype and Fusion Status Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. Jul-Aug, 2009 | Pubmed ID: 18788887 Glomus Tumor Archives of Pathology & Laboratory Medicine. Sep, 2008 | Pubmed ID: 18788860 Cutaneous Sarcomatoid Carcinoma with Features of Giant Cell Tumor of Soft Parts--a Case Report The American Journal of Dermatopathology. Aug, 2008 | Pubmed ID: 18645315 Primary Cardiac Sarcomas: a Clinicopathologic Analysis of a Series with Follow-up Information in 17 Patients and Emphasis on Long-term Survival Human Pathology. Sep, 2008 | Pubmed ID: 18602663 Intraosseous Glomus Tumor of the Great Toe: a Case Report with Review of the Literature The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons. Jul-Aug, 2008 | Pubmed ID: 18590892 Cytoplasmic Overexpression of WT-1 in Gastrointestinal Stromal Tumor and Other Soft Tissue Tumors Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Jul, 2008 | Pubmed ID: 18528287 Myxofibrosarcoma in the Skin Journal of Cutaneous Pathology. Oct, 2008 | Pubmed ID: 18494817 Lymphatic Invasion Revealed by Multispectral Imaging is Common in Primary Melanomas and Associates with Prognosis Human Pathology. Jun, 2008 | Pubmed ID: 18440591 The Selective Expression of CD43 in Adenoid Cystic Carcinoma Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Mar, 2008 | Pubmed ID: 18227725 Patterns and Levels of Hypoxia in Head and Neck Squamous Cell Carcinomas and Their Relationship to Patient Outcome International Journal of Radiation Oncology, Biology, Physics. Nov, 2007 | Pubmed ID: 17967299 Targeting HER-2/neu in Early Breast Cancer Development Using Dendritic Cells with Staged Interleukin-12 Burst Secretion Cancer Research. Feb, 2007 | Pubmed ID: 17293384 Podoplanin is a Highly Sensitive and Specific Marker to Distinguish Primary Skin Adnexal Carcinomas from Adenocarcinomas Metastatic to Skin The American Journal of Surgical Pathology. Feb, 2007 | Pubmed ID: 17255777 Cancer/testis (CT) Antigens Are Expressed in Fetal Ovary Cancer Immunity. 2007 | Pubmed ID: 17217256 Mitotic Recombination As Evidence of Alternative Pathogenesis of Gastrointestinal Stromal Tumours in Neurofibromatosis Type 1 Journal of Medical Genetics. Jan, 2007 | Pubmed ID: 17209131 Extensive Retraction Artifact Correlates with Lymphatic Invasion and Nodal Metastasis and Predicts Poor Outcome in Early Stage Breast Carcinoma The American Journal of Surgical Pathology. Jan, 2007 | Pubmed ID: 17197929 Immunoprofile of Endocervical and Endometrial Stromal Cells and Its Potential Application in Localization of Tumor Involvement International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Jan, 2007 | Pubmed ID: 17197901 D2-40 Functions As an Effective Chondroid Marker Distinguishing True Chondroid Tumors from Chordoma Acta Neuropathologica. Jan, 2007 | Pubmed ID: 17021752 The Impact of Genetics on Sarcoma Diagnosis: an Evolving Science Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2006 | Pubmed ID: 17000654 Can Melan-A Replace S-100 and HMB-45 in the Evaluation of Sentinel Lymph Nodes from Patients with Malignant Melanoma? Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Sep, 2006 | Pubmed ID: 16932024 Complete Endoscopic Resection of an Esophageal Duplication Cyst (with Video) Gastrointestinal Endoscopy. Aug, 2006 | Pubmed ID: 16860091 Diagnostic Utility of Mucin Profile in Fine-needle Aspiration Specimens of the Pancreas: an Immunohistochemical Study with Surgical Pathology Correlation Cancer. Jun, 2006 | Pubmed ID: 16628655 Low Podoplanin Expression in Pretreatment Biopsy Material Predicts Poor Prognosis in Advanced-stage Squamous Cell Carcinoma of the Uterine Cervix Treated by Primary Radiation Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. May, 2006 | Pubmed ID: 16528371 Peritumoral Lymphatic Vessel Density and Vascular Endothelial Growth Factor C Expression in Early-stage Squamous Cell Carcinoma of the Uterine Cervix Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2005 | Pubmed ID: 16322297 Extrathoracic Solitary Fibrous Tumor of the Pelvic Peritoneum with Central Malignant Degeneration on CT and MRI Journal of Magnetic Resonance Imaging : JMRI. Nov, 2005 | Pubmed ID: 16215968 Comparison of P63 and P73 Expression in Benign and Malignant Salivary Gland Lesions Head & Neck. Aug, 2005 | Pubmed ID: 16021638 Lymphatic and Blood Vessel Density in the Follicular Patterned Lesions of Thyroid Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Nov, 2005 | Pubmed ID: 15920537 D2-40, a Novel Monoclonal Antibody Against the M2A Antigen As a Marker to Distinguish Hemangioblastomas from Renal Cell Carcinomas Acta Neuropathologica. May, 2005 | Pubmed ID: 15864611 Case Report: Glomus Tumor of the Colon Annals of Clinical and Laboratory Science. 2005 | Pubmed ID: 15830716 Is the Myofibrillarlytic Myocyte a Forme Fruste Apoptotic Myocyte? The Annals of Thoracic Surgery. Apr, 2005 | Pubmed ID: 15797072 Malignant Fibrous Histiocytoma of the Pharynx AJR. American Journal of Roentgenology. Mar, 2005 | Pubmed ID: 15728001 Low D2-40 Immunoreactivity Correlates with Lymphatic Invasion and Nodal Metastasis in Early-stage Squamous Cell Carcinoma of the Uterine Cervix Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jan, 2005 | Pubmed ID: 15467716 PDGF-A, PDGF-Rbeta, TGFbeta3 and Bone Morphogenic Protein-4 in Desmoplastic Small Round Cell Tumors with EWS-WT1 Gene Fusion Product and Their Role in Stromal Desmoplasia: an Immunohistochemical Study Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Mar, 2005 | Pubmed ID: 15389255 Utility of D2-40, a Novel Mesothelial Marker, in the Diagnosis of Malignant Mesothelioma Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jan, 2005 | Pubmed ID: 15389250 Expression of Melan-A and Ki-67 in Desmoplastic Melanoma and Desmoplastic Nevi The American Journal of Dermatopathology. Dec, 2004 | Pubmed ID: 15618925 Bone Morphogenetic Proteins Are Expressed by Both Bone-forming and Non-bone-forming Lesions Archives of Pathology & Laboratory Medicine. Nov, 2004 | Pubmed ID: 15508192 Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions Archives of Pathology & Laboratory Medicine. 11, 2004 | Pubmed ID: 15506826 Immunohistochemical Evaluation of Microphthalmia-associated Transcription Factor Expression in Giant Cell Lesions Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Dec, 2004 | Pubmed ID: 15205688 The Role of Beta-catenin, TGF Beta 3, NGF2, FGF2, IGFR2, and BMP4 in the Pathogenesis of Mesenteric Sclerosis and Angiopathy in Midgut Carcinoids Human Pathology. Jun, 2004 | Pubmed ID: 15188132 WT1 is Differentially Expressed in Serous, Endometrioid, Clear Cell, and Mucinous Carcinomas of the Peritoneum, Fallopian Tube, Ovary, and Endometrium International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Apr, 2004 | Pubmed ID: 15084838 Fibrillin and Other Matrix Proteins in Mitral Valve Prolapse Syndrome The Annals of Thoracic Surgery. Feb, 2004 | Pubmed ID: 14759433 Cytokeratin 7 Immunoreactivity in Rectal Adenocarcinomas Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Dec, 2003 | Pubmed ID: 14663355 Growth Factors and Receptors in Juvenile Nasopharyngeal Angiofibroma and Nasal Polyps: an Immunohistochemical Study Archives of Pathology & Laboratory Medicine. Nov, 2003 | Pubmed ID: 14567719 Role of Different Immunostaining Patterns in HercepTest Interpretation and Criteria for Gene Amplification As Determined by Fluorescence in Situ Hybridization Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication of the Society for Applied Immunohistochemistry. Sep, 2003 | Pubmed ID: 12966348 Tyrosinase Expression in Malignant Melanoma, Desmoplastic Melanoma, and Peripheral Nerve Tumors Archives of Pathology & Laboratory Medicine. Sep, 2003 | Pubmed ID: 12951966 Corticomedullary Mixed Tumor of the Adrenal Gland with Concurrent Adrenal Myelolipoma Archives of Pathology & Laboratory Medicine. Aug, 2003 | Pubmed ID: 12873195 The Role of Calretinin, Inhibin, Melan-A, BCL-2, and C-kit in Differentiating Adrenal Cortical and Medullary Tumors: an Immunohistochemical Study Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jun, 2003 | Pubmed ID: 12808065 Hypoxia-inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression The American Journal of Pathology. Jun, 2003 | Pubmed ID: 12759237 Expression of Neurotrophin Receptor Trk-C in Nevi and Melanomas Journal of Cutaneous Pathology. May, 2003 | Pubmed ID: 12753172 C-kit Immunoreactivity in Endometrial Adenocarcinomas and Its Clinicopathologic Significance International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Apr, 2003 | Pubmed ID: 12649669 Immunophenotype of Desmoplastic Small Round Cell Tumors As Detected in Cases with EWS-WT1 Gene Fusion Product Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Mar, 2003 | Pubmed ID: 12640103 Detection and Diagnostic Utilization of Placental Alkaline Phosphatase in Muscular Tissue and Tumors with Myogenic Differentiation The American Journal of Surgical Pathology. Dec, 2002 | Pubmed ID: 12459630 Immunohistochemical Expression of Erythropoietin and Erythropoietin Receptor in Breast Carcinoma Cancer. Sep, 2002 | Pubmed ID: 12209679 Clonal Human (hNT) Neuron Grafts for Stroke Therapy: Neuropathology in a Patient 27 Months After Implantation The American Journal of Pathology. Apr, 2002 | Pubmed ID: 11943704 Immunoprofile of MITF, Tyrosinase, Melan-A, and MAGE-1 in HMB45-negative Melanomas The American Journal of Surgical Pathology. Jan, 2002 | Pubmed ID: 11756773 乳腺癌的一种新的转基因小鼠模型:转移性乳腺癌通过瞄准导管上皮与腺病毒Cre重组酶的启动 Melanie R. Rutkowski*1, Michael J. Allegrezza*1, Nikolaos Svoronos1, Amelia J. Tesone1, Tom L. Stephen1, Alfredo Perales-Puchalt1, Jenny Nguyen1, Paul J. Zhang2, Steven N. Fiering3, Julia Tchou4,5,6, Jose R. Conejo-Garcia1 1Tumor Microenvironment and Metastasis Program, Wistar Institute, 2Department of Pathology and Lab Medicine, Perelman School of Medicine, University of Pennsylvania, 3Department of Microbiology and Immunology and Department of Genetics, Geisel School of Medicine at Dartmouth, 4Division of Endocrine and Oncologic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, 5Rena Rowan Breast Center, Abramson Cancer Center, University of Pennsylvania, 6Center for Advanced Medicine, University of Pennsylvania JoVE 51171 Medicine
乳腺癌的一种新的转基因小鼠模型:转移性乳腺癌通过瞄准导管上皮与腺病毒Cre重组酶的启动 Melanie R. Rutkowski*1, Michael J. Allegrezza*1, Nikolaos Svoronos1, Amelia J. Tesone1, Tom L. Stephen1, Alfredo Perales-Puchalt1, Jenny Nguyen1, Paul J. Zhang2, Steven N. Fiering3, Julia Tchou4,5,6, Jose R. Conejo-Garcia1 1Tumor Microenvironment and Metastasis Program, Wistar Institute, 2Department of Pathology and Lab Medicine, Perelman School of Medicine, University of Pennsylvania, 3Department of Microbiology and Immunology and Department of Genetics, Geisel School of Medicine at Dartmouth, 4Division of Endocrine and Oncologic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, 5Rena Rowan Breast Center, Abramson Cancer Center, University of Pennsylvania, 6Center for Advanced Medicine, University of Pennsylvania JoVE 51171 Medicine