Paul W. M. Fedak

Publications

• Potential Role of Epicardial Adipose Tissue in Coronary Artery Endothelial Cell Dysfunction in Type 2 Diabetes
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2021  |   Pubmed ID: 34469050
• Post-Operative Adhesions: A Comprehensive Review of Mechanisms
  Biomedicines. Jul, 2021  |   Pubmed ID: 34440071
• Prevention of Post-Operative Adhesions: A Comprehensive Review of Present and Emerging Strategies
  Biomolecules. 07, 2021  |   Pubmed ID: 34356652
• Aorta-specific DNA Methylation Patterns in Cell-free DNA from Patients with Bicuspid Aortic Valve-associated Aortopathy
  Clinical Epigenetics. Jul, 2021  |   Pubmed ID: 34321094
• International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes
  The Journal of Thoracic and Cardiovascular Surgery. Sep, 2021  |   Pubmed ID: 34304896
• Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional, and Research Purposes
  The Journal of Thoracic and Cardiovascular Surgery. 09, 2021  |   Pubmed ID: 34304894
• Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes
  The Annals of Thoracic Surgery. Sep, 2021  |   Pubmed ID: 34304861
• International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes
  The Annals of Thoracic Surgery. Sep, 2021  |   Pubmed ID: 34304860
• International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes
  European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2021  |   Pubmed ID: 34293102
• Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes
  European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2021  |   Pubmed ID: 34292332
• Commentary: The 4AT Score-Reducing Confusion About Delirium Diagnosis After Cardiac Surgery
  The Journal of Thoracic and Cardiovascular Surgery. Jun, 2021  |   Pubmed ID: 34217535
• Commentary: How to Save and Improve the Lives of Families with Heritable Aortic Diseases
  The Journal of Thoracic and Cardiovascular Surgery. Mar, 2021  |   Pubmed ID: 33781592
• Mechanical and Structural Remodeling of Cardiac Muscle After Aerobic and Resistance Exercise Training in Rats
  Medicine and Science in Sports and Exercise. 08, 2021  |   Pubmed ID: 33731663
• Commentary: Past is Prologue - Leveraging Big Data to Optimize Future Operative Risk Prediction
  Seminars in Thoracic and Cardiovascular Surgery. Mar, 2021  |   Pubmed ID: 33662550
• Commentary: A Picture is Worth a Thousand Words: Improving Surgical Approaches Using Advanced Multimodal Cardiac Imaging
  The Journal of Thoracic and Cardiovascular Surgery. Feb, 2021  |   Pubmed ID: 33642107
• Commentary: The Promise of Precision Cardiovascular Surgery
  The Journal of Thoracic and Cardiovascular Surgery. 02, 2021  |   Pubmed ID: 31818427
• Commentary: Fluoroquinolone Antibiotics Are Antiaortic
  The Journal of Thoracic and Cardiovascular Surgery. Nov, 2020  |   Pubmed ID: 33293062
• Commentary: Transplanting the Powerhouse of the Cell to Enhance Cardiopulmonary Repair
  The Journal of Thoracic and Cardiovascular Surgery. Sep, 2020  |   Pubmed ID: 32980149
• Commentary: The Mutation Matters: Improving Precision for Surgical Management of Hereditary Aortic Syndromes
  The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020  |   Pubmed ID: 32951878
• Commentary: The Return on Investment for Cardiothoracic Surgeon-scientists
  The Journal of Thoracic and Cardiovascular Surgery. Jul, 2020  |   Pubmed ID: 32859412
• Surgical Management of the Aorta in BAV Patients
  Progress in Cardiovascular Diseases. Jul - Aug, 2020  |   Pubmed ID: 32640281
• The Science of BAV Aortopathy
  Progress in Cardiovascular Diseases. Jul - Aug, 2020  |   Pubmed ID: 32599028
• Acellular Bioscaffolds Redirect Cardiac Fibroblasts and Promote Functional Tissue Repair in Rodents and Humans with Myocardial Injury
  Scientific Reports. 06, 2020  |   Pubmed ID: 32528051
• Fluoroquinolone-Associated Type A Aortic Dissection in Alpha-1 Anti-Trypsin Deficiency
  The Annals of Thoracic Surgery. 12, 2020  |   Pubmed ID: 32492444
• Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration
  Journal of Clinical Medicine. May, 2020  |   Pubmed ID: 32380775
• Promoting Cardiac Regeneration and Repair Using Acellular Biomaterials
  Frontiers in Bioengineering and Biotechnology. 2020  |   Pubmed ID: 32363184
• Direct Effects of Empagliflozin on Extracellular Matrix Remodelling in Human Cardiac Myofibroblasts: Novel Translational Clues to Explain EMPA-REG OUTCOME Results
  The Canadian Journal of Cardiology. 04, 2020  |   Pubmed ID: 31837891
• SKA-31, an Activator of Ca-activated K Channels, Improves Cardiovascular Function in Aging
  Pharmacological Research. 01, 2020  |   Pubmed ID: 31707036
• Commentary: Cause or Consequence? The Influence of Mitral Regurgitation on Post-myocardial Infarction Structural Remodeling is Better Defined Using a New Rodent Model
  The Journal of Thoracic and Cardiovascular Surgery. Sep, 2019  |   Pubmed ID: 31610958
• Application of Bioengineered Materials in the Surgical Management of Heart Failure
  Frontiers in Cardiovascular Medicine. 2019  |   Pubmed ID: 31482096
• On the 'cusp' of Clinical Feasibility: Aortic Wall Shear Stress Derived Non-invasively with 4D Flow MRI
  Journal of Thoracic Disease. Jul, 2019  |   Pubmed ID: 31463155
• Gata6 Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis
  Immunity. 07, 2019  |   Pubmed ID: 31315031
• Acellular Extracellular Matrix Bioscaffolds for Cardiac Repair and Regeneration
  Frontiers in Cell and Developmental Biology. 2019  |   Pubmed ID: 31080800
• Minimally Invasive Cardiac Surgery Presents Challenges for Design of Randomized Clinical Trials
  The Journal of Thoracic and Cardiovascular Surgery. 04, 2019  |   Pubmed ID: 30901801
• Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy
  Frontiers in Cardiovascular Medicine. 2019  |   Pubmed ID: 30886849
• Minimally Invasive Cardiac Surgery and the Importance of Qualitative Patient-centered Metrics to Guide Innovations
  The Journal of Thoracic and Cardiovascular Surgery. 06, 2019  |   Pubmed ID: 30871840
• Commentary: Using Ex vivo Modeling to Validate Technical Innovations in Cardiac Surgery
  The Journal of Thoracic and Cardiovascular Surgery. 08, 2019  |   Pubmed ID: 30857816
• Utilizing Wall Shear Stress As a Clinical Biomarker for Bicuspid Valve-associated Aortopathy
  Current Opinion in Cardiology. 03, 2019  |   Pubmed ID: 30633073
• Induction of Human Aortic Myofibroblast-mediated Extracellular Matrix Dysregulation: A Potential Mechanism of Fluoroquinolone-associated Aortopathy
  The Journal of Thoracic and Cardiovascular Surgery. 01, 2019  |   Pubmed ID: 30528439
• Commentary: Structural Valve Degeneration in the Era of Precision Medicine
  The Journal of Thoracic and Cardiovascular Surgery. 04, 2019  |   Pubmed ID: 30389129
• Precision and Targeted Therapy in Cardiac Surgery
  Journal of Thoracic Disease. Nov, 2018  |   Pubmed ID: 30631535
• Targeting Selected Extracellular Matrix Components to Attenuate Cardiac Fibrosis
  Annals of Translational Medicine. Nov, 2018  |   Pubmed ID: 30613624
• Validating Innovations to Improve Recovery After Heart Surgery
  Annals of Translational Medicine. Nov, 2018  |   Pubmed ID: 30613588
• Coronary Bypass Surgery for Diabetes and Multivessel Disease: Forget the SYNTAX
  Journal of the American College of Cardiology. 12, 2018  |   Pubmed ID: 30522647
• Make Sternotomy Great Again
  The Journal of Thoracic and Cardiovascular Surgery. 12, 2018  |   Pubmed ID: 30107920
• Modify, Simplify, Apply: Do We Need Preclinical Models for Surgical Innovation?
  The Journal of Thoracic and Cardiovascular Surgery. 11, 2018  |   Pubmed ID: 30098807
• Aortic Valve-mediated Wall Shear Stress is Heterogeneous and Predicts Regional Aortic Elastic Fiber Thinning in Bicuspid Aortic Valve-associated Aortopathy
  The Journal of Thoracic and Cardiovascular Surgery. 12, 2018  |   Pubmed ID: 30060930
• The American Association for Thoracic Surgery Consensus Guidelines on Bicuspid Aortic Valve-related Aortopathy: Full Online-only Version
  The Journal of Thoracic and Cardiovascular Surgery. 08, 2018  |   Pubmed ID: 30011777
• The American Association for Thoracic Surgery Consensus Guidelines on Bicuspid Aortic Valve-related Aortopathy: Executive Summary
  The Journal of Thoracic and Cardiovascular Surgery. 08, 2018  |   Pubmed ID: 30011756
• Human Pericardial Proteoglycan 4 (lubricin): Implications for Postcardiotomy Intrathoracic Adhesion Formation
  The Journal of Thoracic and Cardiovascular Surgery. 10, 2018  |   Pubmed ID: 29859675
• Using Acellular Bioactive Extracellular Matrix Scaffolds to Enhance Endogenous Cardiac Repair
  Frontiers in Cardiovascular Medicine. 2018  |   Pubmed ID: 29696148
• Aortic Valve Replacement in an Era of Rapid Innovation: Better the Devil You Know
  Journal of the American College of Cardiology. 04, 2018  |   Pubmed ID: 29598860
• Aortic Diameter: The Beginning of the End of an Era
  The Journal of Thoracic and Cardiovascular Surgery. 08, 2018  |   Pubmed ID: 29510930
• Bridging to Heart Transplant with Extracorporeal Membrane Oxygenation: Good or VAD?
  The Journal of Thoracic and Cardiovascular Surgery. 04, 2018  |   Pubmed ID: 29310932
• Seeing a Tree Through the Forest: Precision Medicine Tools Can Enhance Donor Allocation in Heart Transplantation
  The Journal of Thoracic and Cardiovascular Surgery. 04, 2018  |   Pubmed ID: 29310930
• Perioperative Evaluation of Regional Aortic Wall Shear Stress Patterns in Patients Undergoing Aortic Valve And/or Proximal Thoracic Aortic Replacement
  The Journal of Thoracic and Cardiovascular Surgery. 06, 2018  |   Pubmed ID: 29248286
• Bicuspid Aortic Valve-associated Aortopathy: Update on Biomarkers
  Current Opinion in Cardiology. 03, 2018  |   Pubmed ID: 29095713
• Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold
  Tissue Engineering. Part A. 01, 2018  |   Pubmed ID: 28457186
• Bioactive Extracellular Matrix Scaffold Promotes Adaptive Cardiac Remodeling and Repair
  JACC. Basic to Translational Science. Aug, 2017  |   Pubmed ID: 30062163
• Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure
  JACC. Basic to Translational Science. Aug, 2017  |   Pubmed ID: 30062155
• Mind the Gap: Current Challenges and Future State of Heart Failure Care
  The Canadian Journal of Cardiology. 11, 2017  |   Pubmed ID: 29111107
• Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy
  Frontiers in Physiology. 2017  |   Pubmed ID: 28740468
• The Cost of Frailty in Cardiac Surgery
  The Canadian Journal of Cardiology. 08, 2017  |   Pubmed ID: 28666616
• Adhesive-Enhanced Sternal Closure: Feasibility and Safety of Late Sternal Reentry
  Case Reports in Surgery. 2017  |   Pubmed ID: 28634566
• Bicuspid Aortic Valve Aortopathy: Mechanistic and Clinical Insights from Recent Studies
  Current Opinion in Cardiology. Mar, 2017  |   Pubmed ID: 28182589
• Reply: Final Common Pathway of Aortic Dilation?: Heterogeneity of Aortic Wall Property Causes The Aneurysmal Change
  Journal of the American College of Cardiology. Feb, 2016  |   Pubmed ID: 26868701