Paul Witting Redox Biology Group, Discipline of Pathology, School of Medical Sciences University of Sydney Biography Publications Institution JoVE Articles Paul Witting has not added a biography. If you are Paul Witting and would like to personalize this page please email our Author Liaison for assistance. Publications Glutathione Enhances Antibiotic Efficiency and Effectiveness of DNase I in Disrupting Pseudomonas Aeruginosa Biofilms While Also Inhibiting Pyocyanin Activity, Thus Facilitating Restoration of Cell Enzymatic Activity, Confluence and Viability Frontiers in Microbiology. 2017 | Pubmed ID: 29312161 The Nitroxide 4-methoxy TEMPO Inhibits Neutrophil-stimulated Kinase Activation in H9c2 Cardiomyocytes Archives of Biochemistry and Biophysics. Sep, 2017 | Pubmed ID: 28688768 Protective Role for Antioxidants in Acute Kidney Disease Nutrients. Jul, 2017 | Pubmed ID: 28686196 Analogues of Desferrioxamine B Designed to Attenuate Iron-mediated Neurodegeneration: Synthesis, Characterisation and Activity in the MPTP-mouse Model of Parkinson's Disease Metallomics : Integrated Biometal Science. Jul, 2017 | Pubmed ID: 28466891 Neutrophils Recruited to the Myocardium After Acute Experimental Myocardial Infarct Generate Hypochlorous Acid That Oxidizes Cardiac Myoglobin Archives of Biochemistry and Biophysics. Dec, 2016 | Pubmed ID: 27789204 Measuring Redox-active Species in Cells and Tissues. Focus on "A Case of Mistaken Identity: Are Reactive Oxygen Species Actually Reactive Sulfide Species?" American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2016 | Pubmed ID: 26887430 Targeting of Cytosolic Phospholipase A2α Impedes Cell Cycle Re-entry of Quiescent Prostate Cancer Cells Oncotarget. Oct, 2015 | Pubmed ID: 26416244 Serum Amyloid A Receptor Blockade and Incorporation into High-density Lipoprotein Modulates Its Pro-inflammatory and Pro-thrombotic Activities on Vascular Endothelial Cells International Journal of Molecular Sciences. May, 2015 | Pubmed ID: 25988387 Effects of 8 Weeks of CPAP on Lipid-based Oxidative Markers in Obstructive Sleep Apnea: a Randomized Trial Journal of Sleep Research. Jun, 2015 | Pubmed ID: 25533591 XAS Studies of Se Speciation in Selenite-fed Rats Metallomics : Integrated Biometal Science. Dec, 2014 | Pubmed ID: 25363824 Therapeutic Inflammatory Monocyte Modulation Using Immune-modifying Microparticles Science Translational Medicine. Jan, 2014 | Pubmed ID: 24431111 The Smoking-associated Oxidant Hypothiocyanous Acid Induces Endothelial Nitric Oxide Synthase Dysfunction The Biochemical Journal. Jan, 2014 | Pubmed ID: 24112082 Selective Inhibition of the Master Regulator Transcription Factor Egr-1 with Catalytic Oligonucleotides Reduces Myocardial Injury and Improves Left Ventricular Systolic Function in a Preclinical Model of Myocardial Infarction Journal of the American Heart Association. Jul, 2013 | Pubmed ID: 23902638 Oxidative Stress in Alzheimer's Disease: Primary Villain or Physiological By-product? Redox Report : Communications in Free Radical Research. 2013 | Pubmed ID: 23849337 Serum Amyloid A Stimulates Cultured Endothelial Cells to Migrate and Proliferate: Inhibition by the Multikinase Inhibitor BIBF1120 Clinical and Experimental Pharmacology & Physiology. Sep, 2013 | Pubmed ID: 23819722 Selenium Metabolism in Cancer Cells: the Combined Application of XAS and XFM Techniques to the Problem of Selenium Speciation in Biological Systems Nutrients. May, 2013 | Pubmed ID: 23698165 Cytosolic Phospholipase A2α Sustains PAKT, PERK and AR Levels in PTEN-null/mutated Prostate Cancer Cells Biochimica Et Biophysica Acta. Jun, 2013 | Pubmed ID: 23500889 Human Indoleamine 2,3-dioxygenase is a Catalyst of Physiological Heme Peroxidase Reactions: Implications for the Inhibition of Dioxygenase Activity by Hydrogen Peroxide The Journal of Biological Chemistry. Jan, 2013 | Pubmed ID: 23209301 Selenium Inhibits Renal Oxidation and Inflammation but Not Acute Kidney Injury in an Animal Model of Rhabdomyolysis Antioxidants & Redox Signaling. Mar, 2013 | Pubmed ID: 22937747 Beneficial Effects of the Synthetic Antioxidant Tert-butyl Bisphenol on the Hepatic Microcirculation in a Rat Model of Diabetes Mellitus Acta Diabetologica. Aug, 2013 | Pubmed ID: 22183926 Cosupplementation with a Synthetic, Lipid-soluble Polyphenol and Vitamin C Inhibits Oxidative Damage and Improves Vascular Function Yet Does Not Inhibit Acute Renal Injury in an Animal Model of Rhabdomyolysis Free Radical Biology & Medicine. May, 2012 | Pubmed ID: 22343418 Synchrotron Radiation Induced X-ray Emission Studies of the Antioxidant Mechanism of the Organoselenium Drug Ebselen Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Apr, 2012 | Pubmed ID: 22327627 Metabolism of Selenite in Human Lung Cancer Cells: X-ray Absorption and Fluorescence Studies Journal of the American Chemical Society. Nov, 2011 | Pubmed ID: 21957893 The Acute-phase Protein Serum Amyloid A Induces Endothelial Dysfunction That is Inhibited by High-density Lipoprotein Free Radical Biology & Medicine. Oct, 2011 | Pubmed ID: 21784147 Phenolic Antioxidants Tert-butyl-bisphenol and Vitamin E Decrease Oxidative Stress and Enhance Vascular Function in an Animal Model of Rhabdomyolysis Yet Do Not Improve Acute Renal Dysfunction Free Radical Research. Sep, 2011 | Pubmed ID: 21726176 Tissue Vibration Induces Carotid Artery Endothelial Dysfunction: a Mechanism Linking Snoring and Carotid Atherosclerosis? Sleep. Jun, 2011 | Pubmed ID: 21629363 Comparing the Potential Renal Protective Activity of Desferrioxamine B and the Novel Chelator Desferrioxamine B-N-(3-hydroxyadamant-1-yl)carboxamide in a Cell Model of Myoglobinuria The Biochemical Journal. May, 2011 | Pubmed ID: 21320071 Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity Via Mitochondrial Complex II The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21059645 Boronated Phosphonium Salts Containing Arylboronic Acid, Closo-carborane, or Nido-carborane: Synthesis, X-ray Diffraction, in Vitro Cytotoxicity, and Cellular Uptake Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2010 | Pubmed ID: 20694490 The Synthetic Polyphenol Tert-butyl-bisphenol Inhibits Myoglobin-induced Dysfunction in Cultured Kidney Epithelial Cells Free Radical Research. Aug, 2010 | Pubmed ID: 20528578 Silicon Nitride As a Versatile Growth Substrate for Microspectroscopic Imaging and Mapping of Individual Cells Molecular BioSystems. Jul, 2010 | Pubmed ID: 20445927 Neuroglobin Overexpression in Cultured Human Neuronal Cells Protects Against Hydrogen Peroxide Insult Via Activating Phosphoinositide-3 Kinase and Opening the Mitochondrial K(ATP) Channel Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20367258 Kynurenine is an Endothelium-derived Relaxing Factor Produced During Inflammation Nature Medicine. Mar, 2010 | Pubmed ID: 20190767 Conjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators As Potential Agents for Treating Iron Overload Journal of Medicinal Chemistry. Feb, 2010 | Pubmed ID: 20041672 A Role for Acute-phase Serum Amyloid A and High-density Lipoprotein in Oxidative Stress, Endothelial Dysfunction and Atherosclerosis Redox Report : Communications in Free Radical Research. 2009 | Pubmed ID: 19843373 Activated Actin-depolymerizing Factor/cofilin Sequesters Phosphorylated Microtubule-associated Protein During the Assembly of Alzheimer-like Neuritic Cytoskeletal Striations The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2009 | Pubmed ID: 19828813 Pitfalls in the Use of Arachidonic Acid Oxidation Products to Assign Lipoxygenase Activity in Cancer Cells Free Radical Research. Oct, 2009 | Pubmed ID: 19680997 Endogenous Adenosine Selectively Modulates Oxidant Stress Via the A1 Receptor in Ischemic Hearts Antioxidants & Redox Signaling. Nov, 2009 | Pubmed ID: 19552606 Serum Amyloid A Induction of Cytokines in Monocytes/macrophages and Lymphocytes Atherosclerosis. Dec, 2009 | Pubmed ID: 19535079 Molecules in Focus: Cytosolic Phospholipase A2-alpha The International Journal of Biochemistry & Cell Biology. May, 2009 | Pubmed ID: 18761105 Serum Amyloid A May Potentiate Prothrombotic and Proinflammatory Events in Acute Coronary Syndromes Atherosclerosis. Feb, 2009 | Pubmed ID: 18571179 Rat Models of Myocardial Infarction. Pathogenetic Insights and Clinical Relevance Thrombosis and Haemostasis. Nov, 2006 | Pubmed ID: 17080217 Antioxidants Protect from Atherosclerosis by a Heme Oxygenase-1 Pathway That is Independent of Free Radical Scavenging The Journal of Experimental Medicine. Apr, 2006 | Pubmed ID: 16606673 Regio- and Stereo-chemical Oxidation of Linoleic Acid by Human Myoglobin and Hydrogen Peroxide: Tyr(103) Affects Rate and Product Distribution The Biochemical Journal. Jul, 2004 | Pubmed ID: 15035657 Preparação ideal de formol fixada amostras para peptídeo baseado Matrix assistida por espectrometria de massa de ionização/dessorção Laser Imaging fluxos de trabalho Matthew B. O'Rourke1,2, Matthew P. Padula2, Caine Smith3, Priscilla Youssef4, Stuart Cordwell1, Paul Witting4, Greg Sutherland3, Ben Crossett1 1Mass Spectrometry Core Facility, University of Sydney, 2Proteomics Core Facility, University of Technology Sydney, 3Neuropathology Group, Discipline of Pathology, School of Medical Sciences, University of Sydney, 4Redox Biology Group, Discipline of Pathology, School of Medical Sciences, University of Sydney JoVE 56778 Biochemistry
Preparação ideal de formol fixada amostras para peptídeo baseado Matrix assistida por espectrometria de massa de ionização/dessorção Laser Imaging fluxos de trabalho Matthew B. O'Rourke1,2, Matthew P. Padula2, Caine Smith3, Priscilla Youssef4, Stuart Cordwell1, Paul Witting4, Greg Sutherland3, Ben Crossett1 1Mass Spectrometry Core Facility, University of Sydney, 2Proteomics Core Facility, University of Technology Sydney, 3Neuropathology Group, Discipline of Pathology, School of Medical Sciences, University of Sydney, 4Redox Biology Group, Discipline of Pathology, School of Medical Sciences, University of Sydney JoVE 56778 Biochemistry
