Philip A. Barker

Publications

• S100B Protein Activates a RAGE-dependent Autocrine Loop in Astrocytes: Implications for Its Role in the Propagation of Reactive Gliosis
  Journal of Neurochemistry. Jun, 2014  |   Pubmed ID: 24923428
• Neurotrophins in the Regulation of Cellular Survival and Death
  Handbook of Experimental Pharmacology. 2014  |   Pubmed ID: 24668474
• P75 Neurotrophin Receptor Cleavage by α- and γ-secretases is Required for Neurotrophin-mediated Proliferation of Brain Tumor-initiating Cells
  The Journal of Biological Chemistry. Mar, 2014  |   Pubmed ID: 24519935
• XIAP Regulates Caspase Activity in Degenerating Axons
  Cell Reports. Aug, 2013  |   Pubmed ID: 23954782
• Interaction and Antagonistic Roles of NF-κB and Hes6 in the Regulation of Cortical Neurogenesis
  Molecular and Cellular Biology. Jul, 2013  |   Pubmed ID: 23689134
• Wengen, the Sole Tumour Necrosis Factor Receptor in Drosophila, Collaborates with Moesin to Control Photoreceptor Axon Targeting During Development
  PloS One. 2013  |   Pubmed ID: 23544124
• ASPP1/2 Regulate P53-dependent Death of Retinal Ganglion Cells Through PUMA and Fas/CD95 Activation in Vivo
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013  |   Pubmed ID: 23365256
• An Inactivating Caspase 11 Passenger Mutation Originating from the 129 Murine Strain in Mice Targeted for C-IAP1
  The Biochemical Journal. Apr, 2012  |   Pubmed ID: 22332634
• Developing a Methodology for Carbon Isotope Analysis of Lacustrine Diatoms
  Rapid Communications in Mass Spectrometry : RCM. Jun, 2011  |   Pubmed ID: 21594931
• Trk-dependent ADAM17 Activation Facilitates Neurotrophin Survival Signaling
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2011  |   Pubmed ID: 21411748
• Stress-induced Expression of the P75 Neurotrophin Receptor is Regulated by O-GlcNAcylation of the Sp1 Transcription Factor
  Journal of Neurochemistry. Feb, 2011  |   Pubmed ID: 21105874
• TRPC Channels Underlie Cholinergic Plateau Potentials and Persistent Activity in Entorhinal Cortex
  Hippocampus. Apr, 2011  |   Pubmed ID: 20082292
• The P75NTR Intracellular Domain Generated by Neurotrophin-induced Receptor Cleavage Potentiates Trk Signaling
  Journal of Cell Science. Jul, 2010  |   Pubmed ID: 20530577
• LGI1 is a Nogo Receptor 1 Ligand That Antagonizes Myelin-based Growth Inhibition
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2010  |   Pubmed ID: 20463223
• De Novo Mutations in the Gene Encoding the Synaptic Scaffolding Protein SHANK3 in Patients Ascertained for Schizophrenia
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010  |   Pubmed ID: 20385823
• ProNGF Induces TNFalpha-dependent Death of Retinal Ganglion Cells Through a P75NTR Non-cell-autonomous Signaling Pathway
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010  |   Pubmed ID: 20133718
• Cellular Inhibitors of Apoptosis CIAP1 and CIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2
  Immunity. Jun, 2009  |   Pubmed ID: 19464198
• Excitotoxic Death of Retinal Neurons in Vivo Occurs Via a Non-cell-autonomous Mechanism
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009  |   Pubmed ID: 19403821
• A P75(NTR) Pivoting Paradigm Propels Perspicacity
  Neuron. Apr, 2009  |   Pubmed ID: 19376060
• Vasculature Guides Migrating Neuronal Precursors in the Adult Mammalian Forebrain Via Brain-derived Neurotrophic Factor Signaling
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2009  |   Pubmed ID: 19339612
• Nuclear Factor Kappa B Signaling Regulates Neuronal Morphology and Cocaine Reward
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2009  |   Pubmed ID: 19295158
• Whither ProBDNF?
  Nature Neuroscience. Feb, 2009  |   Pubmed ID: 19172162
• Observations on the Function of Nuclear Factor Kappa B (NF-kappaB) in the Survival of Adult Primary Sensory Neurons After Nerve Injury
  Molecular and Cellular Neurosciences. Feb, 2009  |   Pubmed ID: 19049877
• Mutations in the Calcium-related Gene IL1RAPL1 Are Associated with Autism
  Human Molecular Genetics. Dec, 2008  |   Pubmed ID: 18801879
• Edar and Troy Signalling Pathways Act Redundantly to Regulate Initiation of Hair Follicle Development
  Human Molecular Genetics. Nov, 2008  |   Pubmed ID: 18689798
• Apoptotic Sensitivity of Murine IAP-deficient Cells
  The Biochemical Journal. Oct, 2008  |   Pubmed ID: 18684108
• CIAP1 and CIAP2 Facilitate Cancer Cell Survival by Functioning As E3 Ligases That Promote RIP1 Ubiquitination
  Molecular Cell. Jun, 2008  |   Pubmed ID: 18570872
• Soluble Adenylyl Cyclase is Not Required for Axon Guidance to Netrin-1
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008  |   Pubmed ID: 18400890
• Proneurotrophins Require Endocytosis and Intracellular Proteolysis to Induce TrkA Activation
  The Journal of Biological Chemistry. May, 2008  |   Pubmed ID: 18299325
• Photic Injury Promotes Cleavage of P75NTR by TACE and Nuclear Trafficking of the P75 Intracellular Domain
  Molecular and Cellular Neurosciences. Dec, 2007  |   Pubmed ID: 17904861
• Atmospheric Science. The Monsoon's Past
  Science (New York, N.Y.). Jun, 2007  |   Pubmed ID: 17540892
• Something Old, Something New: BDNF-induced Neuron Survival Requires TRPC Channel Function
  Nature Neuroscience. May, 2007  |   Pubmed ID: 17453053
• Stabilization of P73 by Nuclear IkappaB Kinase-alpha Mediates Cisplatin-induced Apoptosis
  The Journal of Biological Chemistry. Jun, 2007  |   Pubmed ID: 17452332
• Hypo-osmolar Stress Induces P75NTR Expression by Activating Sp1-dependent Transcription
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007  |   Pubmed ID: 17287525
• High Affinity Not in the Vicinity?
  Neuron. Jan, 2007  |   Pubmed ID: 17196523
• The Epilepsy Gene LGI1 Encodes a Secreted Glycoprotein That Binds to the Cell Surface
  Human Molecular Genetics. Dec, 2006  |   Pubmed ID: 17067999
• Ligand-dependent Cleavage of the P75 Neurotrophin Receptor is Necessary for NRIF Nuclear Translocation and Apoptosis in Sympathetic Neurons
  Neuron. Apr, 2006  |   Pubmed ID: 16630834
• AEG3482 is an Antiapoptotic Compound That Inhibits Jun Kinase Activity and Cell Death Through Induced Expression of Heat Shock Protein 70
  Chemistry & Biology. Feb, 2006  |   Pubmed ID: 16492569
• Tumor Necrosis Factor-alpha Triggers Mucus Production in Airway Epithelium Through an IkappaB Kinase Beta-dependent Mechanism
  The Journal of Biological Chemistry. Oct, 2005  |   Pubmed ID: 16123045
• P75 Neurotrophin Receptor Reduces Ligand-induced Trk Receptor Ubiquitination and Delays Trk Receptor Internalization and Degradation
  EMBO Reports. Oct, 2005  |   Pubmed ID: 16113645
• Getting RIP'd Stunts Your Growth
  Neuron. Jun, 2005  |   Pubmed ID: 15953410
• Nuclear Factor-kappaB Induced by Doxorubicin is Deficient in Phosphorylation and Acetylation and Represses Nuclear Factor-kappaB-dependent Transcription in Cancer Cells
  Cancer Research. May, 2005  |   Pubmed ID: 15899819
• Characterization of the C-Jun N-terminal Kinase-BimEL Signaling Pathway in Neuronal Apoptosis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2004  |   Pubmed ID: 15470142
• TRAF6-dependent NF-kB Transcriptional Activity During Mouse Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2004  |   Pubmed ID: 15305292
• P75NTR is Positively Promiscuous: Novel Partners and New Insights
  Neuron. May, 2004  |   Pubmed ID: 15157416
• Protein Kinase A Activation Promotes Plasma Membrane Insertion of DCC from an Intracellular Pool: A Novel Mechanism Regulating Commissural Axon Extension
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004  |   Pubmed ID: 15044543
• A Pro-apoptotic Fragment of the P75 Neurotrophin Receptor is Expressed in P75NTRExonIV Null Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2004  |   Pubmed ID: 14985432
• The P75 Neurotrophin Receptor: Multiple Interactors and Numerous Functions
  Progress in Brain Research. 2004  |   Pubmed ID: 14699954
• Apoptosis Induced by P75NTR Overexpression Requires Jun Kinase-dependent Phosphorylation of Bad
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2003  |   Pubmed ID: 14673001
• K252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERK
  The Journal of Biological Chemistry. Dec, 2002  |   Pubmed ID: 12388555
• NRAGE, a P75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death Through a JNK-dependent Mitochondrial Pathway
  The Journal of Biological Chemistry. Dec, 2002  |   Pubmed ID: 12376548
• Constitutive Nuclear Factor-kappa B Activity is Required for Central Neuron Survival
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002  |   Pubmed ID: 12351721
• Expression Analysis of a Novel P75(NTR) Signaling Protein, Which Regulates Cell Cycle Progression and Apoptosis
  Mechanisms of Development. Sep, 2002  |   Pubmed ID: 12204258
• Neurotrophin Signaling Through the P75 Neurotrophin Receptor
  Progress in Neurobiology. Jun, 2002  |   Pubmed ID: 12169297
• Retrograde Signaling by the Neurotrophins Follows a Well-worn Trk
  Trends in Neurosciences. Aug, 2002  |   Pubmed ID: 12127743
• The MAGE Proteins: Emerging Roles in Cell Cycle Progression, Apoptosis, and Neurogenetic Disease
  Journal of Neuroscience Research. Mar, 2002  |   Pubmed ID: 11891783