Philippe J. Sansonetti Molecular Microbial Pathogenesis Unit Institut Pasteur Biography Publications Institution JoVE Articles Philippe J. Sansonetti has not added a biography. If you are Philippe J. Sansonetti and would like to personalize this page please email our Author Liaison for assistance. Publications Cytokine Receptor Cluster Size Impacts Its Endocytosis and Signaling Proceedings of the National Academy of Sciences of the United States of America. Sep, 2021 | Pubmed ID: 34504012 Vitamin C Levels in a Central-African Mother-infant Cohort: Does Hypovitaminosis C Increase the Risk of Enteric Infections? Maternal & Child Nutrition. Jun, 2021 | Pubmed ID: 34137176 Structural Insights of Translocator IpaB and Its Chaperone IpgC in Solution Frontiers in Cellular and Infection Microbiology. 2021 | Pubmed ID: 33996640 High Prevalence of Intestinal Parasite Infestations Among Stunted and Control Children Aged 2 to 5 Years Old in Two Neighborhoods of Antananarivo, Madagascar PLoS Neglected Tropical Diseases. 04, 2021 | Pubmed ID: 33878113 Survival of the Wealthiest? The EMBO Journal. 12, 2020 | Pubmed ID: 33205839 Immunoglobulin Recognition of Fecal Bacteria in Stunted and Non-stunted Children: Findings from the Afribiota Study Microbiome. 07, 2020 | Pubmed ID: 32718353 COVID-19, Chronicle of an Expected Pandemic EMBO Molecular Medicine. 05, 2020 | Pubmed ID: 32259394 Study of the Operon Coding a Two-Component System and a Putative L,D-Carboxypeptidase in Frontiers in Microbiology. 2020 | Pubmed ID: 32194510 Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism Cell Host & Microbe. Mar, 2020 | Pubmed ID: 32101704 Shigella Impairs Human T Lymphocyte Responsiveness by Hijacking Actin Cytoskeleton Dynamics and T Cell Receptor Vesicular Trafficking Cellular Microbiology. 05, 2020 | Pubmed ID: 31957253 Innate Immune Receptor NOD2 Mediates LGR5 Intestinal Stem Cell Protection Against ROS Cytotoxicity Via Mitophagy Stimulation Proceedings of the National Academy of Sciences of the United States of America. 01, 2020 | Pubmed ID: 31919280 Intracellular Offspring Released from SFB Filaments Are Flagellated Nature Microbiology. 01, 2020 | Pubmed ID: 31819216 Colorectal Cancer-associated Microbiota Contributes to Oncogenic Epigenetic Signatures Proceedings of the National Academy of Sciences of the United States of America. 11, 2019 | Pubmed ID: 31712445 Mapping of Shigella Flexneri's Tissue Distribution and Type III Secretion Apparatus Activity During Infection of the Large Intestine of Guinea Pigs Pathogens and Disease. 10, 2019 | Pubmed ID: 31578543 Shigella-mediated Oxygen Depletion is Essential for Intestinal Mucosa Colonization Nature Microbiology. 11, 2019 | Pubmed ID: 31383999 Crypt- and Mucosa-Associated Core Microbiotas in Humans and Their Alteration in Colon Cancer Patients MBio. 07, 2019 | Pubmed ID: 31311881 Promotes Major Alteration of Gut Epithelial Physiology and Tissue Invasion by Shutting off Host Intracellular Transport Proceedings of the National Academy of Sciences of the United States of America. 07, 2019 | Pubmed ID: 31209035 -mediated Immunosuppression in the Human Gut: Subversion Extends from Innate to Adaptive Immune Responses Human Vaccines & Immunotherapeutics. 2019 | Pubmed ID: 30964713 Pathogenesis: New Insights Through Advanced Methodologies Microbiology Spectrum. 03, 2019 | Pubmed ID: 30953429 Expression of the Human Antimicrobial Peptide β-defensin-1 is Repressed by the EGFR-ERK-MYC Axis in Colonic Epithelial Cells Scientific Reports. 12, 2018 | Pubmed ID: 30575780 Natural Molecules Induce and Synergize to Boost Expression of the Human Antimicrobial Peptide β-defensin-3 Proceedings of the National Academy of Sciences of the United States of America. 10, 2018 | Pubmed ID: 30275324 Shigella and Enteroinvasive Escherichia Coli Current Topics in Microbiology and Immunology. 2018 | Pubmed ID: 30218158 Disentangling Host-Microbiota Regulation of Lipid Secretion by Enterocytes: Insights from Commensals and MBio. 09, 2018 | Pubmed ID: 30181250 Stunted Childhood Growth is Associated with Decompartmentalization of the Gastrointestinal Tract and Overgrowth of Oropharyngeal Taxa Proceedings of the National Academy of Sciences of the United States of America. 09, 2018 | Pubmed ID: 30126990 Identifying the Etiology and Pathophysiology Underlying Stunting and Environmental Enteropathy: Study Protocol of the AFRIBIOTA Project BMC Pediatrics. 07, 2018 | Pubmed ID: 30025542 Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion Immunity. 06, 2018 | Pubmed ID: 29858013 Measles 2018: a Tale of Two Anniversaries EMBO Molecular Medicine. 05, 2018 | Pubmed ID: 29685959 MUB Binds to Lactoferrin and Stands As a Specific Neutrophil Marker Cell Chemical Biology. Apr, 2018 | Pubmed ID: 29478905 Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors Trends in Microbiology. 04, 2018 | Pubmed ID: 29477730 Rhinoscleroma Pathogenesis: The Type K3 Capsule of Klebsiella Rhinoscleromatis is a Virulence Factor Not Involved in Mikulicz Cells Formation PLoS Neglected Tropical Diseases. 01, 2018 | Pubmed ID: 29381692 Pathogens, Microbiome and the Host: Emergence of the Ecological Koch's Postulates FEMS Microbiology Reviews. 05, 2018 | Pubmed ID: 29325027 Colorectal Cancer Specific Conditions Promote Gut Colonization Proceedings of the National Academy of Sciences of the United States of America. 01, 2018 | Pubmed ID: 29279402 Editorial: Editorial for the Virtual Issue on Microbiome FEMS Microbiology Reviews. 03, 2018 | Pubmed ID: 29228184 Identification of Novel Substrates of Shigella T3SA Through Analysis of Its Virulence Plasmid-encoded Secretome PloS One. 2017 | Pubmed ID: 29073283 Lipopolysaccharide from Crypt-Specific Core Microbiota Modulates the Colonic Epithelial Proliferation-to-Differentiation Balance MBio. 10, 2017 | Pubmed ID: 29042502 Injection of T3SS Effectors Not Resulting in Invasion is the Main Targeting Mechanism of Toward Human Lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 09, 2017 | Pubmed ID: 28847968 Comparative Genomic Analysis of Acinetobacter Strains Isolated from Murine Colonic Crypts BMC Genomics. 07, 2017 | Pubmed ID: 28697749 Shigella Sonnei Encodes a Functional T6SS Used for Interbacterial Competition and Niche Occupancy Cell Host & Microbe. Jun, 2017 | Pubmed ID: 28618272 Impact of High-fat Diet on the Intestinal Microbiota and Small Intestinal Physiology Before and After the Onset of Obesity Biochimie. May, 2017 | Pubmed ID: 28571979 Segmented Filamentous Bacteria, Th17 Inducers and Helpers in a Hostile World Current Opinion in Microbiology. Feb, 2017 | Pubmed ID: 28453971 Threonine Eliminylation by Bacterial Phosphothreonine Lyases Rapidly Causes Cross-linking of Mitogen-activated Protein Kinase (MAPK) in Live Cells The Journal of Biological Chemistry. May, 2017 | Pubmed ID: 28325837 Moving Molecular Medicine EMBO Molecular Medicine. Apr, 2017 | Pubmed ID: 28314782 Candidate Immune Biomarkers for Radioimmunotherapy Biochimica Et Biophysica Acta. Feb, 2017 | Pubmed ID: 28254528 CD34+ Mesenchymal Cells Are a Major Component of the Intestinal Stem Cells Niche at Homeostasis and After Injury Proceedings of the National Academy of Sciences of the United States of America. Jan, 2017 | Pubmed ID: 28074039 The Infectious Hypoxia: Occurrence and Causes During Shigella Infection Microbes and Infection. Mar, 2017 | Pubmed ID: 27884799 [Microbiota-intestinal Stem Cells Dialog: a Key Element for Intestinal Regeneration] Medecine Sciences : M/S. Nov, 2016 | Pubmed ID: 28008839 Complete Genome Sequence of Delftia Tsuruhatensis CM13 Isolated from Murine Proximal Colonic Tissue Genome Announcements. Dec, 2016 | Pubmed ID: 27979948 Multifaceted Functions of NOD-Like Receptor Proteins in Myeloid Cells at the Intersection of Innate and Adaptive Immunity Microbiology Spectrum. Aug, 2016 | Pubmed ID: 27726775 From Homeostasis to Pathology: Decrypting Microbe-host Symbiotic Signals in the Intestinal Crypt Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Nov, 2016 | Pubmed ID: 27672151 High-fat Diet Modifies the PPAR-γ Pathway Leading to Disruption of Microbial and Physiological Ecosystem in Murine Small Intestine Proceedings of the National Academy of Sciences of the United States of America. Oct, 2016 | Pubmed ID: 27638207 Intestinal Organoids As a Novel Tool to Study Microbes-Epithelium Interactions Methods in Molecular Biology (Clifton, N.J.). Sep, 2016 | Pubmed ID: 27628134 Anoxia and Glucose Supplementation Preserve Neutrophil Viability and Function Blood. Aug, 2016 | Pubmed ID: 27402974 Shigella Flexneri Modulates Stress Granule Composition and Inhibits Stress Granule Aggregation Cellular Microbiology. 07, 2016 | Pubmed ID: 27282465 Histone Deacetylase Inhibition Enhances Antimicrobial Peptide but Not Inflammatory Cytokine Expression Upon Bacterial Challenge Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27162363 Shigella Diversity and Changing Landscape: Insights for the Twenty-First Century Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27148494 A Synthetic Carbohydrate Conjugate Vaccine Candidate Against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity Bioconjugate Chemistry. Apr, 2016 | Pubmed ID: 26918643 PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment Cell Reports. Feb, 2016 | Pubmed ID: 26776508 Draft Genome Sequences of Acinetobacter Parvus CM11, Acinetobacter Radioresistens CM38, and Stenotrophomonas Maltophilia BR12, Isolated from Murine Proximal Colonic Tissue Genome Announcements. Oct, 2015 | Pubmed ID: 26472823 Diet and Specific Microbial Exposure Trigger Features of Environmental Enteropathy in a Novel Murine Model Nature Communications. Aug, 2015 | Pubmed ID: 26241678 Bioimage Analysis of Shigella Infection Reveals Targeting of Colonic Crypts Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 26056271 Escape of Actively Secreting Shigella Flexneri from ATG8/LC3-Positive Vacuoles Formed During Cell-To-Cell Spread Is Facilitated by IcsB and VirA MBio. May, 2015 | Pubmed ID: 26015503 Functional Genomic Screen Identifies Klebsiella Pneumoniae Factors Implicated in Blocking Nuclear Factor κB (NF-κB) Signaling The Journal of Biological Chemistry. Jul, 2015 | Pubmed ID: 25971969 Mucosal Physical and Chemical Innate Barriers: Lessons from Microbial Evasion Strategies Seminars in Immunology. Mar, 2015 | Pubmed ID: 25936225 An O Antigen Capsule Modulates Bacterial Pathogenesis in Shigella Sonnei PLoS Pathogens. Mar, 2015 | Pubmed ID: 25794007 Pathogen Manipulation of B Cells: the Best Defence is a Good Offence Nature Reviews. Microbiology. Mar, 2015 | Pubmed ID: 25659322 Growth and Host Interaction of Mouse Segmented Filamentous Bacteria in Vitro Nature. Apr, 2015 | Pubmed ID: 25600271 Apical Invasion of Intestinal Epithelial Cells by Salmonella Typhimurium Requires Villin to Remodel the Brush Border Actin Cytoskeleton Cell Host & Microbe. Feb, 2015 | Pubmed ID: 25600187 TOM1 is a PI5P Effector Involved in the Regulation of Endosomal Maturation Journal of Cell Science. Feb, 2015 | Pubmed ID: 25588840 Type III Secretion System Current Biology : CB. Sep, 2014 | Pubmed ID: 25202865 The Cofilin Phosphatase Slingshot Homolog 1 (SSH1) Links NOD1 Signaling to Actin Remodeling PLoS Pathogens. Sep, 2014 | Pubmed ID: 25187968 Rapid 96-well Plates DNA Extraction and Sequencing Procedures to Identify Genome-wide Transposon Insertion Sites in a Difficult to Lyse Bacterium: Lactobacillus Casei Journal of Microbiological Methods. Nov, 2014 | Pubmed ID: 25135488 Functional Genomics of Lactobacillus Casei Establishment in the Gut Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014 | Pubmed ID: 25024222 The Cytosolic Bacterial Peptidoglycan Sensor Nod2 Affords Stem Cell Protection and Links Microbes to Gut Epithelial Regeneration Cell Host & Microbe. Jun, 2014 | Pubmed ID: 24882705 B Lymphocytes Undergo TLR2-dependent Apoptosis Upon Shigella Infection The Journal of Experimental Medicine. Jun, 2014 | Pubmed ID: 24863068 Tracking Bacterial Pathogens with Genetically-encoded Reporters FEBS Letters. Aug, 2014 | Pubmed ID: 24859085 Non-stoichiometric O-acetylation of Shigella Flexneri 2a O-specific Polysaccharide: Synthesis and Antigenicity Organic & Biomolecular Chemistry. Jun, 2014 | Pubmed ID: 24836582 The LacdiNAc-specific Adhesin LabA Mediates Adhesion of Helicobacter Pylori to Human Gastric Mucosa The Journal of Infectious Diseases. Oct, 2014 | Pubmed ID: 24755437 New Insights into the Crosstalk Between Shigella and T Lymphocytes Trends in Microbiology. Apr, 2014 | Pubmed ID: 24613405 ZapE is a Novel Cell Division Protein Interacting with FtsZ and Modulating the Z-ring Dynamics MBio. Mar, 2014 | Pubmed ID: 24595368 A Fluorescent Reporter Reveals On/off Regulation of the Shigella Type III Secretion Apparatus During Entry and Cell-to-cell Spread Cell Host & Microbe. Feb, 2014 | Pubmed ID: 24528864 A Shigella Effector Dampens Inflammation by Regulating Epithelial Release of Danger Signal ATP Through Production of the Lipid Mediator PtdIns5P Immunity. Dec, 2013 | Pubmed ID: 24332032 Microbiota and the Immune System, an Amazing Mutualism Forged by Co-evolution Seminars in Immunology. Nov, 2013 | Pubmed ID: 24269722 Virulent Shigella Flexneri Affects Secretion, Expression, and Glycosylation of Gel-forming Mucins in Mucus-producing Cells Infection and Immunity. Oct, 2013 | Pubmed ID: 23876800 Epithelial Cell Proliferation Arrest Induced by Lactate and Acetate from Lactobacillus Casei and Bifidobacterium Breve PloS One. 2013 | Pubmed ID: 23646174 A Novel Murine Model of Rhinoscleroma Identifies Mikulicz Cells, the Disease Signature, As IL-10 Dependent Derivatives of Inflammatory Monocytes EMBO Molecular Medicine. Apr, 2013 | Pubmed ID: 23554169 Shigella Impairs T Lymphocyte Dynamics in Vivo Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23417297 [Acute Intestinal Infections: Current and Upcoming Vaccines] Presse Medicale (Paris, France : 1983). Jan, 2013 | Pubmed ID: 23237786 Shigella Effector IpaB-induced Cholesterol Relocation Disrupts the Golgi Complex and Recycling Network to Inhibit Host Cell Secretion Cell Host & Microbe. Sep, 2012 | Pubmed ID: 22980334 Quantitative RT-PCR Profiling of the Rabbit Immune Response: Assessment of Acute Shigella Flexneri Infection PloS One. 2012 | Pubmed ID: 22675469 A Crypt-specific Core Microbiota Resides in the Mouse Colon MBio. 2012 | Pubmed ID: 22617141 Characterization of the Promoter, MxiE Box and 5' UTR of Genes Controlled by the Activity of the Type III Secretion Apparatus in Shigella Flexneri PloS One. 2012 | Pubmed ID: 22427898 Design of a Specific Colonic Mucus Marker Using a Human Commensal Bacterium Cell Surface Domain The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22427651 ATP-mediated Erk1/2 Activation Stimulates Bacterial Capture by Filopodia, Which Precedes Shigella Invasion of Epithelial Cells Cell Host & Microbe. Jun, 2011 | Pubmed ID: 21669399 The Shigella Flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism Cell Host & Microbe. Apr, 2011 | Pubmed ID: 21501826 Antigen-specific CD8(+) T Cells Fail to Respond to Shigella Flexneri Infection and Immunity. May, 2011 | Pubmed ID: 21357720 Breathing Life into Pathogens: the Influence of Oxygen on Bacterial Virulence and Host Responses in the Gastrointestinal Tract Cellular Microbiology. Feb, 2011 | Pubmed ID: 21166974 Framing a Concept and an Agenda for Infectious Diseases in EMBO Molecular Medicine EMBO Molecular Medicine. Jul, 2009 | Pubmed ID: 20049719 Learning Tolerance While Fighting Ignorance Cell. Aug, 2009 | Pubmed ID: 19665961 Characterisation of Early Mucosal and Neuronal Lesions Following Shigella Flexneri Infection in Human Colon PloS One. 2009 | Pubmed ID: 19274103 A Synthetic Carbohydrate-protein Conjugate Vaccine Candidate Against Shigella Flexneri 2a Infection Journal of Immunology (Baltimore, Md. : 1950). Feb, 2009 | Pubmed ID: 19201878 The IpaC Carboxyterminal Effector Domain Mediates Src-dependent Actin Polymerization During Shigella Invasion of Epithelial Cells PLoS Pathogens. Jan, 2009 | Pubmed ID: 19165331 赤痢菌 T3SS エフェクター IpaH の構造は、E3 ユビキチンリ ガーゼの新しいクラスを定義します。 Nature Structural & Molecular Biology. Dec, 2008 | Pubmed ID: 18997778 Vaccination Against Shigellosis: is It the Path That is Difficult or is It the Difficult That is the Path? Microbes and Infection. Jul, 2008 | Pubmed ID: 18672087 Host-bacteria Homeostasis in the Healthy and Inflamed Gut Current Opinion in Gastroenterology. Jul, 2008 | Pubmed ID: 18622156 Virulent Shigella Flexneri Subverts the Host Innate Immune Response Through Manipulation of Antimicrobial Peptide Gene Expression The Journal of Experimental Medicine. May, 2008 | Pubmed ID: 18426984 Phase 1 Clinical Trial of Live Attenuated Shigella Dysenteriae Type-1 DeltaicsA Deltaent Deltafep DeltastxA:HgR Oral Vaccine SC599 in Healthy Human Adult Volunteers Vaccine. Feb, 2008 | Pubmed ID: 18207287 Cytoplasmic Targeting of IpaC to the Bacterial Pole Directs Polar Type III Secretion in Shigella The EMBO Journal. Jan, 2008 | Pubmed ID: 18188151 Molecular and Cellular Bases of Bacterial Virulence: Guessing the Future Episodes of an Ongoing Saga Research in Microbiology. Jan-Feb, 2008 | Pubmed ID: 18162373 The Pattern-recognition Molecule Nod1 is Localized at the Plasma Membrane at Sites of Bacterial Interaction Cellular Microbiology. Feb, 2008 | Pubmed ID: 17970764 Epigenetic Regulation of Host Response to LPS: Causing Tolerance While Avoiding Toll Errancy Cell Host & Microbe. Jun, 2007 | Pubmed ID: 18005703 Type III Secretion Effectors of the IpaH Family Are E3 Ubiquitin Ligases Cell Host & Microbe. Mar, 2007 | Pubmed ID: 18005683 Debugging How Bacteria Manipulate the Immune Response Immunity. Feb, 2007 | Pubmed ID: 17307704 アクチン フィラメントの赤痢菌 IpaA のカルボキシル末端ドメインによってアクティブ ビンキュリンでキャッピング。 FEBS Letters. Mar, 2007 | Pubmed ID: 17289036 Shigella's Ways of Manipulating the Host Intestinal Innate and Adaptive Immune System: a Tool Box for Survival? Immunology and Cell Biology. Feb-Mar, 2007 | Pubmed ID: 17213832 Sensing of Bacteria: NOD a Lonely Job Current Opinion in Microbiology. Feb, 2007 | Pubmed ID: 17161646 An Injected Bacterial Effector Targets Chromatin Access for Transcription Factor NF-kappaB to Alter Transcription of Host Genes Involved in Immune Responses Nature Immunology. Jan, 2007 | Pubmed ID: 17159983 Rupture, Invasion and Inflammatory Destruction of the Intestinal Barrier by Shigella: the Yin and Yang of Innate Immunity The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Medicale. Mar, 2006 | Pubmed ID: 18418486 The Innate Signaling of Dangers and the Dangers of Innate Signaling Nature Immunology. Dec, 2006 | Pubmed ID: 17110939 The Bacterial Weaponry: Lessons from Shigella Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057210 Shigellosis: an Old Disease in New Clothes? PLoS Medicine. Sep, 2006 | Pubmed ID: 16968125 PtdIns5P Activates the Host Cell PI3-kinase/Akt Pathway During Shigella Flexneri Infection The EMBO Journal. Mar, 2006 | Pubmed ID: 16482216 Magnetic Resonance Imaging of Klebsiella Pneumoniae-induced Pneumonia in Mice Cellular Microbiology. Jan, 2006 | Pubmed ID: 16367864 Murine Nod1 but Not Its Human Orthologue Mediates Innate Immune Detection of Tracheal Cytotoxin EMBO Reports. Dec, 2005 | Pubmed ID: 16211083 Identification of the Critical Residues Involved in Peptidoglycan Detection by Nod1 The Journal of Biological Chemistry. Nov, 2005 | Pubmed ID: 16172124 The Shigella Flexneri Effector OspG Interferes with Innate Immune Responses by Targeting Ubiquitin-conjugating Enzymes Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16162672 Adherence Modifies the Regulation of Gene Expression Induced by Interleukin-10 Cytokine. Jan, 2005 | Pubmed ID: 15579372 War and Peace at Mucosal Surfaces Nature Reviews. Immunology. Dec, 2004 | Pubmed ID: 15573130 Nod1 Responds to Peptidoglycan Delivered by the Helicobacter Pylori Cag Pathogenicity Island Nature Immunology. Nov, 2004 | Pubmed ID: 15489856 IL-8 is a Key Chemokine Regulating Neutrophil Recruitment in a New Mouse Model of Shigella-induced Colitis Journal of Immunology (Baltimore, Md. : 1950). Sep, 2004 | Pubmed ID: 15356171 CortactinおよびCrkは、上皮細胞の赤痢菌の侵入時にはアクチン重合をトリガーするために協力 The Journal of Cell Biology. Jul, 2004 | Pubmed ID: 15263018 Bacterial Invasion: the Paradigms of Enteroinvasive Pathogens Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15073367 Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2 The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12871942 Anti-inflammatory Role for Intracellular Dimeric Immunoglobulin a by Neutralization of Lipopolysaccharide in Epithelial Cells Immunity. Jun, 2003 | Pubmed ID: 12818156 The Invasive Phenotype of Shigella Flexneri Directs a Distinct Gene Expression Pattern in the Human Intestinal Epithelial Cell Line Caco-2 The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12813033 Nod1 Detects a Unique Muropeptide from Gram-negative Bacterial Peptidoglycan Science (New York, N.Y.). Jun, 2003 | Pubmed ID: 12791997 Shigella Interaction with Intestinal Epithelial Cells Determines the Innate Immune Response in Shigellosis International Journal of Medical Microbiology : IJMM. Apr, 2003 | Pubmed ID: 12755366 Gene-environment Interaction Modulated by Allelic Heterogeneity in Inflammatory Diseases Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12626759 Identification of the Cis-acting Site Involved in Activation of Promoters Regulated by Activity of the Type III Secretion Apparatus in Shigella Flexneri Journal of Bacteriology. Dec, 2002 | Pubmed ID: 12446624 Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri Effector IpgD Reorganizes Host Cell Morphology The EMBO Journal. Oct, 2002 | Pubmed ID: 12356723 Human Monocytes Kill Shigella Flexneri but then Die by Apoptosis Associated with Suppression of Proinflammatory Cytokine Production Infection and Immunity. Jul, 2002 | Pubmed ID: 12065527 The Contribution of Accessory Toxins of Vibrio Cholerae O1 El Tor to the Proinflammatory Response in a Murine Pulmonary Cholera Model The Journal of Experimental Medicine. Jun, 2002 | Pubmed ID: 12045243 急性細菌性赤痢のアポトーシスはFas / Fasリガンド、パーフォリン、カスパーゼ1、カスパーゼ3の増産がBcl-2とインターロイキン2産生の減少に関係している Infection and Immunity. Jun, 2002 | Pubmed ID: 12011015 Two MsbB Genes Encoding Maximal Acylation of Lipid A Are Required for Invasive Shigella Flexneri to Mediate Inflammatory Rupture and Destruction of the Intestinal Epithelium Journal of Immunology (Baltimore, Md. : 1950). May, 2002 | Pubmed ID: 11994481 Intracellular Vs Extracellular Recognition of Pathogens--common Concepts in Mammals and Flies Trends in Microbiology. Apr, 2002 | Pubmed ID: 11912027 Predominance of Serotype-specific Mucosal Antibody Response in Shigella Flexneri-infected Humans Living in an Area of Endemicity Infection and Immunity. Sep, 2001 | Pubmed ID: 11500390 CARD4/Nod1 Mediates NF-kappaB and JNK Activation by Invasive Shigella Flexneri EMBO Reports. Aug, 2001 | Pubmed ID: 11463746 Parameters Underlying Successful Protection with Live Attenuated Mutants in Experimental Shigellosis Infection and Immunity. Feb, 2001 | Pubmed ID: 11160004 Induction of Necrosis in Human Neutrophils by Shigella Flexneri Requires Type III Secretion, IpaB and IpaC Invasins, and Actin Polymerization Infection and Immunity. Mar, 2000 | Pubmed ID: 10678940 Increased Interleukin-1 (IL-1) and Imbalance Between IL-1 and IL-1 Receptor Antagonist During Acute Inflammation in Experimental Shigellosis Infection and Immunity. Nov, 1999 | Pubmed ID: 10531267 Activation of the CDC42 Effector N-WASP by the Shigella Flexneri IcsA Protein Promotes Actin Nucleation by Arp2/3 Complex and Bacterial Actin-based Motility The Journal of Cell Biology. Sep, 1999 | Pubmed ID: 10491394 Vaccination Against Shigellosis with Attenuated Shigella Flexneri 2a Strain SC602 Infection and Immunity. Jul, 1999 | Pubmed ID: 10377124 Trafficking of Shigella Lipopolysaccharide in Polarized Intestinal Epithelial Cells The Journal of Cell Biology. May, 1999 | Pubmed ID: 10330399 Immunogenicity of IpaC-hybrid Proteins Expressed in the Shigella Flexneri 2a Vaccine Candidate SC602 Infection and Immunity. Jan, 1998 | Pubmed ID: 9423842 活性酸素種感受性蛍光発生プローブを用いたマウス腸管オルガノイドの酸化ストレス解析 Aline Stedman1,3, Antonin Levy1,4, Philippe J. Sansonetti1,2,5, Giulia Nigro1,6 1Molecular Microbial Pathogenesis Unit, Institut Pasteur, 2Chaire de Microbiologie et Maladies Infectieuses, Collège de France, 3Institut de Biologie Paris Seine (IBPS) - Developmental Biology Unit, Sorbonne Université, CNRS UMR7622, INSERM U1156, 4Molecular Radiotherapy, INSERM U1030, Gustave Roussy, Université Paris-Saclay, 5The Center for Microbes, Development and Health, Institut Pasteur Shanghai and Chinese Academy of Sciences, 6Microenvironment and Immunity Unit, Institut Pasteur JoVE 62880 Biology 哺乳動物細胞の細菌攻撃後のストレス顆粒形成の免疫蛍光分析 Pascale Vonaesch1, Philippe J. Sansonetti1,2, Pamela Schnupf3 1Unité de Pathogénie Microbienne Moléculaire, INSERM U786, Institut Pasteur, 2Microbiologie et Maladies Infectieuses, Collège de France, 3Laboratory of Intestinal Immunity, Institut Imagine-INSERM UMR 1163, Université Paris Descartes-Sorbonne Paris Cité JoVE 55536 Immunology and Infection
活性酸素種感受性蛍光発生プローブを用いたマウス腸管オルガノイドの酸化ストレス解析 Aline Stedman1,3, Antonin Levy1,4, Philippe J. Sansonetti1,2,5, Giulia Nigro1,6 1Molecular Microbial Pathogenesis Unit, Institut Pasteur, 2Chaire de Microbiologie et Maladies Infectieuses, Collège de France, 3Institut de Biologie Paris Seine (IBPS) - Developmental Biology Unit, Sorbonne Université, CNRS UMR7622, INSERM U1156, 4Molecular Radiotherapy, INSERM U1030, Gustave Roussy, Université Paris-Saclay, 5The Center for Microbes, Development and Health, Institut Pasteur Shanghai and Chinese Academy of Sciences, 6Microenvironment and Immunity Unit, Institut Pasteur JoVE 62880 Biology
哺乳動物細胞の細菌攻撃後のストレス顆粒形成の免疫蛍光分析 Pascale Vonaesch1, Philippe J. Sansonetti1,2, Pamela Schnupf3 1Unité de Pathogénie Microbienne Moléculaire, INSERM U786, Institut Pasteur, 2Microbiologie et Maladies Infectieuses, Collège de France, 3Laboratory of Intestinal Immunity, Institut Imagine-INSERM UMR 1163, Université Paris Descartes-Sorbonne Paris Cité JoVE 55536 Immunology and Infection
