Philippe Georgel ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Centre de Recherche d'Immunologie et d'Hématologie Université de Strasbourg Biography Publications Institution JoVE Articles Philippe Georgel has not added a biography. If you are Philippe Georgel and would like to personalize this page please email our Author Liaison for assistance. Publications The MiR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation During Rheumatoid Arthritis Frontiers in Immunology. 2013 | Pubmed ID: 23516027 MiR-20a Regulates ASK1 Expression and TLR4-dependent Cytokine Release in Rheumatoid Fibroblast-like Synoviocytes Annals of the Rheumatic Diseases. Jun, 2013 | Pubmed ID: 23087182 ENU-induced Phenovariance in Mice: Inferences from 587 Mutations BMC Research Notes. 2012 | Pubmed ID: 23095377 Deregulation of Type I IFN-dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice PloS One. 2012 | Pubmed ID: 22916300 MeCP2 Binds to Nucleosome Free (linker DNA) Regions and to H3K9/H3K27 Methylated Nucleosomes in the Brain Nucleic Acids Research. Apr, 2012 | Pubmed ID: 22144686 TLR2 Expression is Regulated by MicroRNA MiR-19 in Rheumatoid Fibroblast-like Synoviocytes Journal of Immunology (Baltimore, Md. : 1950). Jan, 2012 | Pubmed ID: 22105995 MeCP2: Structure and Function Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Feb, 2011 | Pubmed ID: 21326358 The Non-conventional MHC Class I MR1 Molecule Controls Infection by Klebsiella Pneumoniae in Mice Molecular Immunology. Feb, 2011 | Pubmed ID: 21190736 Slc15a4, AP-3, and Hermansky-Pudlak Syndrome Proteins Are Required for Toll-like Receptor Signaling in Plasmacytoid Dendritic Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21045126 Virus-host Interactions in Hepatitis C Virus Infection: Implications for Molecular Pathogenesis and Antiviral Strategies Trends in Molecular Medicine. Jun, 2010 | Pubmed ID: 20537953 Silencing and Re-expression of Retinoic Acid Receptor Beta2 in Human Melanoma Pigment Cell & Melanoma Research. Jun, 2010 | Pubmed ID: 20374520 Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis Viruses. Dec, 2009 | Pubmed ID: 21994556 The Heterogeneous Allelic Repertoire of Human Toll-like Receptor (TLR) Genes PloS One. 2009 | Pubmed ID: 19924287 Genetic and Epigenetic Regulations of Prostate Cancer by Genistein Drug News & Perspectives. Jun, 2009 | Pubmed ID: 19609462 Chromatin Stability at Low Concentration Depends on Histone Octamer Saturation Levels Biophysical Journal. Mar, 2009 | Pubmed ID: 19254554 Role of Nucleic Acid Binding in Sir3p-dependent Interactions with Chromatin Fibers Biochemistry. Jan, 2009 | Pubmed ID: 19099415 ENU Mutagenesis in Mice Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370145 TLR4/CD14-mediated PI3K Activation is an Essential Component of Interferon-dependent VSV Resistance in Macrophages Molecular Immunology. May, 2008 | Pubmed ID: 18339426 Role of Chromatin/epigenetic Modifications on DNA Accessibility Drug News & Perspectives. Nov, 2007 | Pubmed ID: 18176659 CHD Proteins: a Diverse Family with Strong Ties Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2007 | Pubmed ID: 17713581 Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-deficient Mice is Due to Impaired MiR24 and MiR93 Expression Immunity. Jul, 2007 | Pubmed ID: 17613256 The Use of Quantitative Agarose Gel Electrophoresis for Rapid Analysis of the Integrity of Protein-DNA Complexes Journal of Biochemical and Biophysical Methods. Aug, 2007 | Pubmed ID: 17604110 Vesicular Stomatitis Virus Glycoprotein G Activates a Specific Antiviral Toll-like Receptor 4-dependent Pathway Virology. Jun, 2007 | Pubmed ID: 17292937 [Toll-dependent and Toll-independent Innate Antiviral Immunity] Médecine Sciences : M/S. Nov, 2006 | Pubmed ID: 17101098 Cell-associated Double-stranded RNA Enhances Antitumor Activity Through the Production of Type I IFN Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006 | Pubmed ID: 17056539 Genetic Analysis of Innate Immunity Advances in Immunology. 2006 | Pubmed ID: 16938541 GAGA Protein: a Multi-faceted Transcription Factor Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2006 | Pubmed ID: 16936828 Details of Toll-like Receptor:adapter Interaction Revealed by Germ-line Mutagenesis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16832055 HDAC1 Acetylation is Linked to Progressive Modulation of Steroid Receptor-induced Gene Transcription Molecular Cell. Jun, 2006 | Pubmed ID: 16762839 Analysis of the MCMV Resistome by ENU Mutagenesis Mammalian Genome : Official Journal of the International Mammalian Genome Society. May, 2006 | Pubmed ID: 16688530 Characterization of Chromatin Samples in the Presence of Drosophila Embryo Extract by Quantitative Agarose Gel Electrophoresis Journal of Biochemical and Biophysical Methods. Jun, 2006 | Pubmed ID: 16580731 Genetic Analysis of Host Resistance: Toll-like Receptor Signaling and Immunity at Large Annual Review of Immunology. 2006 | Pubmed ID: 16551253 R-form LPS, the Master Key to the Activation OfTLR4/MD-2-positive Cells European Journal of Immunology. Mar, 2006 | Pubmed ID: 16506285 The Unc93b1 Mutation 3d Disrupts Exogenous Antigen Presentation and Signaling Via Toll-like Receptors 3, 7 and 9 Nature Immunology. Feb, 2006 | Pubmed ID: 16415873 Genetic Analysis of Innate Resistance to Mouse Cytomegalovirus (MCMV) Briefings in Functional Genomics & Proteomics. Nov, 2005 | Pubmed ID: 16420746 Chromatin Potentiation of the Hsp70 Promoter is Linked to GAGA-factor Recruitment Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2005 | Pubmed ID: 16094459 Chromatin Remodeling Complexes: ATP-dependent Machines in Action Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. Aug, 2005 | Pubmed ID: 16094444 A Toll-like Receptor 2-responsive Lipid Effector Pathway Protects Mammals Against Skin Infections with Gram-positive Bacteria Infection and Immunity. Aug, 2005 | Pubmed ID: 16040962 Genetic Analysis of Innate Immunity: Identification and Function of the TIR Adapter Proteins Advances in Experimental Medicine and Biology. 2005 | Pubmed ID: 15934170 CD14 is Required for MyD88-independent LPS Signaling Nature Immunology. Jun, 2005 | Pubmed ID: 15895089 CD36 is a Sensor of Diacylglycerides Nature. Feb, 2005 | Pubmed ID: 15690042 Genetic Dissection of Innate Immunity to Infection: the Mouse Cytomegalovirus Model Current Opinion in Immunology. Feb, 2005 | Pubmed ID: 15653308 Genetic Analysis of Innate Immunity: TIR Adapter Proteins in Innate and Adaptive Immune Responses Microbes and Infection / Institut Pasteur. Dec, 2004 | Pubmed ID: 15596123 Expansion and Function of CD8+ T Cells Expressing Ly49 Inhibitory Receptors Specific for MHC Class I Molecules Journal of Immunology (Baltimore, Md. : 1950). Sep, 2004 | Pubmed ID: 15356124 To the 30-nm Chromatin Fiber and Beyond Biochimica Et Biophysica Acta. Mar, 2004 | Pubmed ID: 15020041 Toll-like Receptors 9 and 3 As Essential Components of Innate Immune Defense Against Mouse Cytomegalovirus Infection Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14993594 Biophysical Analysis of Specific Genomic Loci Assembled As Chromatin in Vivo Methods in Enzymology. 2004 | Pubmed ID: 14975296 Lps2 and Signal Transduction in Sepsis: at the Intersection of Host Responses to Bacteria and Viruses Scandinavian Journal of Infectious Diseases. 2003 | Pubmed ID: 14620135 Formation of Higher-order Secondary and Tertiary Chromatin Structures by Genomic Mouse Mammary Tumor Virus Promoters Genes & Development. Jul, 2003 | Pubmed ID: 12842912 Chromatin Compaction by Human MeCP2. Assembly of Novel Secondary Chromatin Structures in the Absence of DNA Methylation The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12788925 Quantitative Characterization of Specific Genomic Promoters Using Agarose Gel Electrophoresis Biopolymers. Apr, 2003 | Pubmed ID: 12666180 The Drosophila Immune Defense Against Gram-negative Infection Requires the Death Protein DFADD Immunity. Nov, 2002 | Pubmed ID: 12433364 Differential Core Histone Binding Behavior: RNA Polymerase I Promoter Region Vs 5S RDNA Positioning DNA Sequences Cell Biochemistry and Biophysics. 2002 | Pubmed ID: 12398413 Chromatin Structure of Eukaryotic Promoters: a Changing Perspective Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 2002 | Pubmed ID: 12123282 Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates Eleonore Ostermann1, Cécile Macquin1, Seiamak Bahram1, Philippe Georgel1 1ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Centre de Recherche d'Immunologie et d'Hématologie, Université de Strasbourg JoVE 50409 Immunology and Infection
Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates Eleonore Ostermann1, Cécile Macquin1, Seiamak Bahram1, Philippe Georgel1 1ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Centre de Recherche d'Immunologie et d'Hématologie, Université de Strasbourg JoVE 50409 Immunology and Infection