Pierre Hardy Departments of Pediatrics and Pharmacology University of Montréal Biography Publications Institution JoVE Articles Pierre Hardy has not added a biography. If you are Pierre Hardy and would like to personalize this page please email our Author Liaison for assistance. Publications Retinal Neurons Curb Inflammation and Enhance Revascularization in Ischemic Retinopathies Via Proteinase-Activated Receptor-2 The American Journal of Pathology. Feb, 2015 | Pubmed ID: 25478809 Subcellular Localization of Coagulation Factor II Receptor-like 1 in Neurons Governs Angiogenesis Nature Medicine. Oct, 2014 | Pubmed ID: 25216639 Anti-proliferative and Anti-tumour Effects of Lymphocyte-derived Microparticles Are Neither Species- nor Tumour-type Specific Journal of Extracellular Vesicles. 2014 | Pubmed ID: 24834146 Lymphocyte-derived Microparticles Induce Apoptosis of Airway Epithelial Cells Through Activation of P38 MAPK and Production of Arachidonic Acid Apoptosis : an International Journal on Programmed Cell Death. Jul, 2014 | Pubmed ID: 24777398 P75 Neurotrophin Receptor Participates in the Choroidal Antiangiogenic and Apoptotic Effects of T-lymphocyte-derived Microparticles Investigative Ophthalmology & Visual Science. Sep, 2013 | Pubmed ID: 23920372 Microglia and Interleukin-1β in Ischemic Retinopathy Elicit Microvascular Degeneration Through Neuronal Semaphorin-3A Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2013 | Pubmed ID: 23766263 Fatty Acid Receptor Gpr40 Mediates Neuromicrovascular Degeneration Induced by Transarachidonic Acids in Rodents Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2013 | Pubmed ID: 23520164 Lymphocyte-derived Microparticles Induce Bronchial Epithelial Cells' Pro-inflammatory Cytokine Production and Apoptosis Molecular Immunology. Oct, 2013 | Pubmed ID: 23517738 Role of Receptor-mediated Endocytosis in the Antiangiogenic Effects of Human T Lymphoblastic Cell-derived Microparticles American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2012 | Pubmed ID: 22338082 Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis Through GHSR-1a Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21642627 Choroidal Involution is a Key Component of Oxygen-induced Retinopathy Investigative Ophthalmology & Visual Science. Aug, 2011 | Pubmed ID: 21546530 Cortactin Activation by FVIIa/tissue Factor and PAR2 Promotes Endothelial Cell Migration American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2011 | Pubmed ID: 21160057 CD36 Plays an Important Role in the Clearance of OxLDL and Associated Age-dependent Sub-retinal Deposits Aging. Dec, 2010 | Pubmed ID: 21098885 Retinopathy of Prematurity: Understanding Ischemic Retinal Vasculopathies at an Extreme of Life The Journal of Clinical Investigation. Sep, 2010 | Pubmed ID: 20811158 Low Density Lipoprotein Receptor Mediates Anti-VEGF Effect of Lymphocyte T-derived Microparticles in Lewis Lung Carcinoma Cells Cancer Biology & Therapy. Sep, 2010 | Pubmed ID: 20603610 Sustained Hypercapnia Induces Cerebral Microvascular Degeneration in the Immature Brain Through Induction of Nitrative Stress American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2010 | Pubmed ID: 20357019 Understanding Ischemic Retinopathies: Emerging Concepts from Oxygen-induced Retinopathy Documenta Ophthalmologica. Advances in Ophthalmology. Feb, 2010 | Pubmed ID: 19882183 Hypoxia Up-regulates CD36 Expression and Function Via Hypoxia-inducible Factor-1- and Phosphatidylinositol 3-kinase-dependent Mechanisms The Journal of Biological Chemistry. Sep, 2009 | Pubmed ID: 19640849 The Role of Lysophosphatidic Acid Receptor (LPA1) in the Oxygen-induced Retinal Ganglion Cell Degeneration Investigative Ophthalmology & Visual Science. Mar, 2009 | Pubmed ID: 18978343 Interleukin-1 and Ischemic Brain Injury in the Newborn: Development of a Small Molecule Inhibitor of IL-1 Receptor Seminars in Perinatology. Oct, 2008 | Pubmed ID: 18929155 The Succinate Receptor GPR91 in Neurons Has a Major Role in Retinal Angiogenesis Nature Medicine. Oct, 2008 | Pubmed ID: 18836459 Genetic Ablation of CD36 Induces Age-related Corneal Neovascularization Cornea. Oct, 2008 | Pubmed ID: 18812768 Trans-Arachidonic Acids Induce a Heme Oxygenase-dependent Vasorelaxation of Cerebral Microvasculature Free Radical Biology & Medicine. Mar, 2008 | Pubmed ID: 18082639 Lymphocytic Microparticles Inhibit Angiogenesis by Stimulating Oxidative Stress and Negatively Regulating VEGF-induced Pathways American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2008 | Pubmed ID: 18046016 Lysophosphatidic Acid Induces Endothelial Cell Death by Modulating the Redox Environment American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2007 | Pubmed ID: 17122328 Hyperoxic Exposure Leads to Nitrative Stress and Ensuing Microvascular Degeneration and Diminished Brain Mass and Function in the Immature Subject Stroke; a Journal of Cerebral Circulation. Nov, 2006 | Pubmed ID: 17008616 Activation of CD36 Inhibits and Induces Regression of Inflammatory Corneal Neovascularization Investigative Ophthalmology & Visual Science. Oct, 2006 | Pubmed ID: 17003426 Hypercapnia Prevents Neovascularization Via Nitrative Stress Free Radical Biology & Medicine. Feb, 2006 | Pubmed ID: 16443170 Dominant Role for Calpain in Thromboxane-induced Neuromicrovascular Endothelial Cytotoxicity The Journal of Pharmacology and Experimental Therapeutics. Feb, 2006 | Pubmed ID: 16214879 Inflammatory Lipid Mediators in Ischemic Retinopathy Pharmacological Reports : PR. 2005 | Pubmed ID: 16415498 Trans-arachidonic Acids Generated During Nitrative Stress Induce a Thrombospondin-1-dependent Microvascular Degeneration Nature Medicine. Dec, 2005 | Pubmed ID: 16311602 New Insights into the Retinal Circulation: Inflammatory Lipid Mediators in Ischemic Retinopathy Prostaglandins, Leukotrienes, and Essential Fatty Acids. May, 2005 | Pubmed ID: 15850712 Redox-dependent Effects of Nitric Oxide on Microvascular Integrity in Oxygen-induced Retinopathy Free Radical Biology & Medicine. Dec, 2004 | Pubmed ID: 15528047 Pharmacokinetics and Safety of the Ketolide Telithromycin in Patients with Renal Impairment Journal of Clinical Pharmacology. Mar, 2004 | Pubmed ID: 14973302 PGE(2)-mediated ENOS Induction in Prolonged Hypercapnia Investigative Ophthalmology & Visual Science. May, 2002 | Pubmed ID: 11980874 Generación de linfocítica micropartículas y detección de su efecto proapoptótico sobre las células epiteliales de la vía aérea Chun Yang*1, Wei Xiong*2, Qian Qiu2, Houda Tahiri1, Carmen Gagnon1, Guoxiang Liu2, Pierre Hardy1 1Departments of Pediatrics and Pharmacology, University of Montréal, 2Department of Pulmonology, Chongqing Southwest Hospital, Third Military Medical University JoVE 52651 Immunology and Infection
Generación de linfocítica micropartículas y detección de su efecto proapoptótico sobre las células epiteliales de la vía aérea Chun Yang*1, Wei Xiong*2, Qian Qiu2, Houda Tahiri1, Carmen Gagnon1, Guoxiang Liu2, Pierre Hardy1 1Departments of Pediatrics and Pharmacology, University of Montréal, 2Department of Pulmonology, Chongqing Southwest Hospital, Third Military Medical University JoVE 52651 Immunology and Infection
