R. Grace Zhai

Publications

• Nmnat Mitigates Sensory Dysfunction in a Model of Paclitaxel-induced Peripheral Neuropathy
  Disease Models & Mechanisms. Jun, 2018  |   Pubmed ID: 29716954
• Publisher Correction: Spermine Synthase Deficiency Causes Lysosomal Dysfunction and Oxidative Stress in Models of Snyder-Robinson Syndrome
  Nature Communications. Jan, 2018  |   Pubmed ID: 29348635
• Spermine Synthase Deficiency Causes Lysosomal Dysfunction and Oxidative Stress in Models of Snyder-Robinson Syndrome
  Nature Communications. Nov, 2017  |   Pubmed ID: 29097652
• NMNAT: It's an NAD Synthase… It's a Chaperone… It's a Neuroprotector
  Current Opinion in Genetics & Development. Jun, 2017  |   Pubmed ID: 28445802
• Attenuation of Polyglutamine-induced Toxicity by Enhancement of Mitochondrial OXPHOS in Yeast and Fly Models of Aging
  Microbial Cell (Graz, Austria). Jul, 2016  |   Pubmed ID: 28357370
• Alternative Splicing of Drosophila Nmnat Functions As a Switch to Enhance Neuroprotection Under Stress
  Nature Communications. Nov, 2015  |   Pubmed ID: 26616331
• Nicotinamide Mononucleotide Adenylyltransferase Maintains Active Zone Structure by Stabilizing Bruchpilot
  EMBO Reports. Jan, 2013  |   Pubmed ID: 23154466
• Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 Via Unanchored Ubiquitin C Termini
  The Journal of Biological Chemistry. Jan, 2012  |   Pubmed ID: 22069321
• CREB-activity and Nmnat2 Transcription Are Down-regulated Prior to Neurodegeneration, While NMNAT2 Over-expression is Neuroprotective, in a Mouse Model of Human Tauopathy
  Human Molecular Genetics. Jan, 2012  |   Pubmed ID: 22027994
• NMNAT Suppresses Tau-induced Neurodegeneration by Promoting Clearance of Hyperphosphorylated Tau Oligomers in a Drosophila Model of Tauopathy
  Human Molecular Genetics. Jan, 2012  |   Pubmed ID: 21965302
• Nmnat Exerts Neuroprotective Effects in Dendrites and Axons
  Molecular and Cellular Neurosciences. Sep, 2011  |   Pubmed ID: 21596138
• Nicotinamide Mononucleotide Adenylyltransferase is a Stress Response Protein Regulated by the Heat Shock Factor/hypoxia-inducible Factor 1alpha Pathway
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21478149
• β-N-Methylamino-L-alanine Induces Neurological Deficits and Shortened Life Span in Drosophila
  Toxins. Nov, 2010  |   Pubmed ID: 22069570
• Dealing with Misfolded Proteins: Examining the Neuroprotective Role of Molecular Chaperones in Neurodegeneration
  Molecules (Basel, Switzerland). 2010  |   Pubmed ID: 20938400
• BMAA Neurotoxicity in Drosophila
  Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 2009  |   Pubmed ID: 19929734
• Nicotinamide/nicotinic Acid Mononucleotide Adenylyltransferase, New Insights into an Ancient Enzyme
  Cellular and Molecular Life Sciences : CMLS. Sep, 2009  |   Pubmed ID: 19448972
• NAD Synthase NMNAT Acts As a Chaperone to Protect Against Neurodegeneration
  Nature. Apr, 2008  |   Pubmed ID: 18344983
• Drosophila NMNAT Maintains Neural Integrity Independent of Its NAD Synthesis Activity
  PLoS Biology. Nov, 2006  |   Pubmed ID: 17132048
• Activity-independent Prespecification of Synaptic Partners in the Visual Map of Drosophila
  Current Biology : CB. Sep, 2006  |   Pubmed ID: 16979562
• The V-ATPase V0 Subunit A1 is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila
  Cell. May, 2005  |   Pubmed ID: 15907473
• Mutations in Drosophila Sec15 Reveal a Function in Neuronal Targeting for a Subset of Exocyst Components
  Neuron. Apr, 2005  |   Pubmed ID: 15848801
• Hauling T-SNAREs on the Microtubule Highway
  Nature Cell Biology. Oct, 2004  |   Pubmed ID: 15459718
• The Architecture of the Active Zone in the Presynaptic Nerve Terminal
  Physiology (Bethesda, Md.). Oct, 2004  |   Pubmed ID: 15381754
• Synaptojanin is Recruited by Endophilin to Promote Synaptic Vesicle Uncoating
  Neuron. Nov, 2003  |   Pubmed ID: 14622578
• Mapping Drosophila Mutations with Molecularly Defined P Element Insertions
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003  |   Pubmed ID: 12960394
• Unitary Assembly of Presynaptic Active Zones from Piccolo-Bassoon Transport Vesicles
  Neuron. Apr, 2003  |   Pubmed ID: 12718858
• Molecular Mechanisms of CNS Synaptogenesis
  Trends in Neurosciences. May, 2002  |   Pubmed ID: 11972960