Rafael Linden

Publications

• Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration
  Investigative Ophthalmology & Visual Science. 02, 2022  |   Pubmed ID: 35103748
• Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions
  Cells. 07, 2021  |   Pubmed ID: 34359994
• Dissociation of Genotype-dependent Cognitive and Motor Behavior in a Strain of Aging Mice Devoid of the Prion Protein
  Behavioural Brain Research. 08, 2021  |   Pubmed ID: 34052264
• Retinal Genomic Fabric Remodeling After Optic Nerve Injury
  Genes. 03, 2021  |   Pubmed ID: 33799827
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)
  Autophagy. Feb, 2021  |   Pubmed ID: 33634751
• Cell Proliferation in the Central Nervous System of an Adult Semiterrestrial Crab
  Cell and Tissue Research. Apr, 2021  |   Pubmed ID: 33599819
• Neuroprotection from Optic Nerve Injury and Modulation of Oxidative Metabolism by Transplantation of Active Mitochondria to the Retina
  Biochimica Et Biophysica Acta. Molecular Basis of Disease. 05, 2020  |   Pubmed ID: 31953215
• Substrain-related Dependence of Cu(I)-ATPase Activity Among Prion Protein-null Mice
  Brain Research. 01, 2020  |   Pubmed ID: 31726043
• A Subacute Model of Glaucoma Based on Limbal Plexus Cautery in Pigmented Rats
  Scientific Reports. 11, 2019  |   Pubmed ID: 31705136
• Retina Transduction by RAAV2 After Intravitreal Injection: Comparison Between Mouse and Rat
  Gene Therapy. 12, 2019  |   Pubmed ID: 31562387
• Genesis of Retinal Ganglion Cells by Targeted Expression of
  Development (Cambridge, England). 08, 2019  |   Pubmed ID: 31405994
• RAAV8-733-Mediated Gene Transfer of CHIP/Stub-1 Prevents Hippocampal Neuronal Death in Experimental Brain Ischemia
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 02, 2017  |   Pubmed ID: 28153090
• The Prion Protein Selectively Binds to and Modulates the Content of Purinergic Receptor P2X4R
  Biochemical and Biophysical Research Communications. Apr, 2016  |   Pubmed ID: 26946358
• Increased P53 and Decreased P21 Accompany Apoptosis Induced by Ultraviolet Radiation in the Nervous System of a Crustacean
  Aquatic Toxicology (Amsterdam, Netherlands). Apr, 2016  |   Pubmed ID: 26807499
• Reply to Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice
  The Journal of Biological Chemistry. Oct, 2015  |   Pubmed ID: 26500296
• Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice
  The Journal of Biological Chemistry. Aug, 2015  |   Pubmed ID: 26152722
• Antioxidant Activity Stimulated by Ultraviolet Radiation in the Nervous System of a Crustacean
  Aquatic Toxicology (Amsterdam, Netherlands). Mar, 2015  |   Pubmed ID: 25630046
• CHIP, a Carboxy Terminus HSP-70 Interacting Protein, Prevents Cell Death Induced by Endoplasmic Reticulum Stress in the Central Nervous System
  Frontiers in Cellular Neuroscience. 2014  |   Pubmed ID: 25620910
• A Snapshot of Gene Therapy in Latin America
  Genetics and Molecular Biology. Mar, 2014  |   Pubmed ID: 24764763
• Pleiotropic Functions of Pituitary Adenylyl Cyclase-activating Polypeptide on Retinal Ontogenesis: Involvement of KLF4 in the Control of Progenitor Cell Proliferation
  Journal of Molecular Neuroscience : MN. Nov, 2014  |   Pubmed ID: 24715357
• Advances in Recombinant Adeno-associated Viral Vectors for Gene Delivery
  Current Gene Therapy. Oct, 2013  |   Pubmed ID: 24060313
• Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22910907
• Allosteric Function and Dysfunction of the Prion Protein
  Cellular and Molecular Life Sciences : CMLS. Apr, 2012  |   Pubmed ID: 21984610
• Platelet Activating Factor Blocks Interkinetic Nuclear Migration in Retinal Progenitors Through an Arrest of the Cell Cycle at the S/G2 Transition
  PloS One. Jan, 2011  |   Pubmed ID: 21298035
• Protein Kinases JAK and ERK Mediate Protective Effect of Interleukin-2 Upon Ganglion Cells of the Developing Rat Retina
  Journal of Neuroimmunology. Apr, 2011  |   Pubmed ID: 21262542
• Rod Photoreceptor Cell Death is Induced by Okadaic Acid Through Activation of PKC and L-type Voltage-dependent Ca2+ Channels and Prevented by IGF-1
  Neurochemistry International. Sep, 2010  |   Pubmed ID: 20466029
• ATP Controls Cell Cycle and Induces Proliferation in the Mouse Developing Retina
  International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Feb, 2010  |   Pubmed ID: 19799993
• Interleukin-4 Blocks Thapsigargin-induced Cell Death in Rat Rod Photoreceptors: Involvement of CAMP/PKA Pathway
  Journal of Neuroscience Research. Jul, 2009  |   Pubmed ID: 19235892
• Ras Pathway Activation in Gliomas: a Strategic Target for Intranasal Administration of Perillyl Alcohol
  Archivum Immunologiae Et Therapiae Experimentalis. Jul-Aug, 2008  |   Pubmed ID: 18726148
• Endocytosis of Prion Protein is Required for ERK1/2 Signaling Induced by Stress-inducible Protein 1
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008  |   Pubmed ID: 18579743
• Physiology of the Prion Protein
  Physiological Reviews. Apr, 2008  |   Pubmed ID: 18391177
• Interleukin-4 Blocks Proliferation of Retinal Progenitor Cells and Increases Rod Photoreceptor Differentiation Through Distinct Signaling Pathways
  Journal of Neuroimmunology. May, 2008  |   Pubmed ID: 18378323
• DNA Damage-induced Cell Death: Lessons from the Central Nervous System
  Cell Research. Jan, 2008  |   Pubmed ID: 18087290
• Development of a Ligand Blot Assay Using Biotinylated Live Cells
  Journal of Biomolecular Screening. Oct, 2007  |   Pubmed ID: 17942794
• STI1 Promotes Glioma Proliferation Through MAPK and PI3K Pathways
  Glia. Dec, 2007  |   Pubmed ID: 17886292
• Hop/STI1 Modulates Retinal Proliferation and Cell Death Independent of PrPC
  Biochemical and Biophysical Research Communications. Sep, 2007  |   Pubmed ID: 17651690
• Antifungal Pisum Sativum Defensin 1 Interacts with Neurospora Crassa Cyclin F Related to the Cell Cycle
  Biochemistry. Jan, 2007  |   Pubmed ID: 17240982
• A Conserved Domain of the Gp85/trans-sialidase Family Activates Host Cell Extracellular Signal-regulated Kinase and Facilitates Trypanosoma Cruzi Infection
  Experimental Cell Research. Jan, 2007  |   Pubmed ID: 17101128
• Requirement of P38 Stress-activated MAP Kinase for Cell Death in the Developing Retina Depends on the Stage of Cell Differentiation
  Neurochemistry International. Oct, 2006  |   Pubmed ID: 16782232
• Neuritogenesis and Neuronal Differentiation Promoted by 2,4-dinitrophenol, a Novel Anti-amyloidogenic Compound
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2005  |   Pubmed ID: 16195371
• Control of Programmed Cell Death by Neurotransmitters and Neuropeptides in the Developing Mammalian Retina
  Progress in Retinal and Eye Research. Jul, 2005  |   Pubmed ID: 15845345
• The Surfer Wears a Suit. A Report on the II Symposium on Creativity, Imagination and Interactivity in Science Education
  Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. Mar, 2005  |   Pubmed ID: 15761610
• The Cellular Prion Protein Modulates Phagocytosis and Inflammatory Response
  Journal of Leukocyte Biology. Feb, 2005  |   Pubmed ID: 15539455
• Biosynthesis and Metabolism of Sulfated Glycosaminoglycans During Drosophila Melanogaster Development
  Glycobiology. Jun, 2004  |   Pubmed ID: 15044397
• Alternative Programs of Cell Death in Developing Retinal Tissue
  The Journal of Biological Chemistry. Oct, 2003  |   Pubmed ID: 12917395
• Hydrogen Peroxide Induces Caspase Activation and Programmed Cell Death in the Amitochondrial Tritrichomonas Foetus
  Histochemistry and Cell Biology. Aug, 2003  |   Pubmed ID: 12844218
• Structure of Laminin Substrate Modulates Cellular Signaling for Neuritogenesis
  Journal of Cell Science. Dec, 2002  |   Pubmed ID: 12432074
• Fas Ligand Triggers Pulmonary Silicosis
  The Journal of Experimental Medicine. Jul, 2001  |   Pubmed ID: 11457890
• The Anti-death League: Associative Control of Apoptosis in Developing Retinal Tissue
  Brain Research. Brain Research Reviews. Apr, 2000  |   Pubmed ID: 10751664
• Nuclear Exclusion of Transcription Factors Associated with Apoptosis in Developing Nervous Tissue
  Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. Jul, 1999  |   Pubmed ID: 10454738