Ramon Arens

Publications

• A Poly-neoantigen DNA Vaccine Synergizes with PD-1 Blockade to Induce T Cell-mediated Tumor Control
  Oncoimmunology. 2019  |   Pubmed ID: 31646082
• PD-L1 Blockade Engages Tumor-infiltrating Lymphocytes to Co-express Targetable Activating and Inhibitory Receptors
  Journal for Immunotherapy of Cancer. Aug, 2019  |   Pubmed ID: 31412943
• CD8+ T Cells Protect During Vein Graft Disease Development
  Frontiers in Cardiovascular Medicine. 2019  |   Pubmed ID: 31263704
• The Hallmarks of CMV-specific CD8 T-cell Differentiation
  Medical Microbiology and Immunology. Aug, 2019  |   Pubmed ID: 30989333
• Peripheral and Systemic Antigens Elicit an Expandable Pool of Resident Memory CD8 T Cells in the Bone Marrow
  European Journal of Immunology. Jun, 2019  |   Pubmed ID: 30891737
• T Cell Co-stimulation and Co-inhibition in Cardiovascular Disease: a Double-edged Sword
  Nature Reviews. Cardiology. Jun, 2019  |   Pubmed ID: 30770894
• Demarcated Thresholds of Tumor-specific CD8 T Cells Elicited by MCMV-based Vaccine Vectors Provide Robust Correlates of Protection
  Journal for Immunotherapy of Cancer. 01, 2019  |   Pubmed ID: 30704520
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  Science Immunology. 12, 2018  |   Pubmed ID: 30552101
• : A Workflow for Visual and Quantitative Analysis of Flow and Mass Cytometry Data to Discover Immune Signatures and Correlations
  Computational and Structural Biotechnology Journal. 2018  |   Pubmed ID: 30450167
• Cytomegalovirus Infection and Progressive Differentiation of Effector-memory T Cells
  F1000Research. 2018  |   Pubmed ID: 30345004
• OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites
  Frontiers in Cellular and Infection Microbiology. 2018  |   Pubmed ID: 30073152
• FcγRI Expression on Macrophages is Required for Antibody-mediated Tumor Protection by Cytomegalovirus-based Vaccines
  Oncotarget. Jun, 2018  |   Pubmed ID: 30034625
• Impact of Congenital Cytomegalovirus Infection on Transcriptomes from Archived Dried Blood Spots in Relation to Long-term Clinical Outcome
  PloS One. 2018  |   Pubmed ID: 30024899
• A Flexible MHC Class I Multimer Loading System for Large-scale Detection of Antigen-specific T Cells
  The Journal of Experimental Medicine. 05, 2018  |   Pubmed ID: 29666167
• Features of Effective T Cell-Inducing Vaccines Against Chronic Viral Infections
  Frontiers in Immunology. 2018  |   Pubmed ID: 29503649
• Exhaustion and Inflation at Antipodes of T Cell Responses to Chronic Virus Infection
  Trends in Microbiology. 06, 2018  |   Pubmed ID: 29249600
• Human Plasmacytoid Dendritic Cells Acquire Phagocytic Capacity by TLR9 Ligation in the Presence of Soluble Factors Produced by Renal Epithelial Cells
  Kidney International. 02, 2018  |   Pubmed ID: 29061332
• The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose
  Frontiers in Immunology. 2017  |   Pubmed ID: 29367854
• CMV Immune Evasion and Manipulation of the Immune System with Aging
  GeroScience. 06, 2017  |   Pubmed ID: 28647908
• CD4 T Cell and NK Cell Interplay Key to Regression of MHC Class I Tumors Upon TLR7/8 Agonist Therapy
  Cancer Immunology Research. 08, 2017  |   Pubmed ID: 28637878
• Inhibition of 14q32 MicroRNA MiR-495 Reduces Lesion Formation, Intimal Hyperplasia and Plasma Cholesterol Levels in Experimental Restenosis
  Atherosclerosis. 06, 2017  |   Pubmed ID: 28445809
• Enforced OX40 Stimulation Empowers Booster Vaccines to Induce Effective CD4 and CD8 T Cell Responses Against Mouse Cytomegalovirus Infection
  Frontiers in Immunology. 2017  |   Pubmed ID: 28265272
• The Importance of Correctly Timing Cancer Immunotherapy
  Expert Opinion on Biological Therapy. 01, 2017  |   Pubmed ID: 27802061
• Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors
  PLoS Pathogens. Dec, 2016  |   Pubmed ID: 27977791
• Wnt Signaling As Master Regulator of T-Lymphocyte Responses: Implications for Transplant Therapy
  Transplantation. Dec, 2016  |   Pubmed ID: 27861287
• Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination
  Frontiers in Immunology. 2016  |   Pubmed ID: 27656185
• The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy Against Mouse Cytomegalovirus Infection
  PLoS Pathogens. 09, 2016  |   Pubmed ID: 27637068
• Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
  Cancer Research. 10, 2016  |   Pubmed ID: 27569212
• Vaccination During Myeloid Cell Depletion by Cancer Chemotherapy Fosters Robust T Cell Responses
  Science Translational Medicine. Apr, 2016  |   Pubmed ID: 27075626
• Vaccines for Established Cancer: Overcoming the Challenges Posed by Immune Evasion
  Nature Reviews. Cancer. Apr, 2016  |   Pubmed ID: 26965076
• Viral Persistence Induces Antibody Inflation Without Altering Antibody Avidity
  Journal of Virology. May, 2016  |   Pubmed ID: 26889035
• In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity
  Immunity. Feb, 2016  |   Pubmed ID: 26872694
• Murine Cytomegalovirus (CMV) Infection Via the Intranasal Route Offers a Robust Model of Immunity Upon Mucosal CMV Infection
  The Journal of General Virology. Jan, 2016  |   Pubmed ID: 26555192
• Cytomegalovirus- and Epstein-Barr Virus-Induced T-Cell Expansions in Young Children Do Not Impair Naive T-cell Populations or Vaccination Responses: The Generation R Study
  The Journal of Infectious Diseases. Jan, 2016  |   Pubmed ID: 26142434
• The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2015  |   Pubmed ID: 26453748
• Abatacept Decreases Disease Activity in a Absence of CD4(+) T Cells in a Collagen-induced Arthritis Model
  Arthritis Research & Therapy. Aug, 2015  |   Pubmed ID: 26290328
• The Viral Context Instructs the Redundancy of Costimulatory Pathways in Driving CD8(+) T Cell Expansion
  ELife. Aug, 2015  |   Pubmed ID: 26263500
• Therapeutic Cancer Vaccines
  The Journal of Clinical Investigation. Sep, 2015  |   Pubmed ID: 26214521
• New Approaches in Vaccine-based Immunotherapy for Human Papillomavirus-induced Cancer
  Current Opinion in Immunology. Aug, 2015  |   Pubmed ID: 26001120
• Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression
  Cancer Immunology Research. Sep, 2015  |   Pubmed ID: 25888578
• 5(th) International Workshop on CMV and Immunosenescence - A Shadow of Cytomegalovirus Infection on Immunological Memory
  European Journal of Immunology. Apr, 2015  |   Pubmed ID: 25857239
• Enhanced CD8 T Cell Responses Through GITR-mediated Costimulation Resolve Chronic Viral Infection
  PLoS Pathogens. Mar, 2015  |   Pubmed ID: 25738498
• CD55 Deposited on Synovial Collagen Fibers Protects from Immune Complex-mediated Arthritis
  Arthritis Research & Therapy. Jan, 2015  |   Pubmed ID: 25596646
• Vaccine-induced Tumor Necrosis Factor-producing T Cells Synergize with Cisplatin to Promote Tumor Cell Death
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2015  |   Pubmed ID: 25501579
• The Activation of the Adaptive Immune System: Cross-talk Between Antigen-presenting Cells, T Cells and B Cells
  Immunology Letters. Dec, 2014  |   Pubmed ID: 25455596
• T Cell Factor 1 Represses CD8+ Effector T Cell Formation and Function
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2014  |   Pubmed ID: 25355919
• Enhanced Cross-presentation and Improved CD8+ T Cell Responses After Mannosylation of Synthetic Long Peptides in Mice
  PloS One. 2014  |   Pubmed ID: 25137039
• New Advances in CMV and Immunosenescence
  Experimental Gerontology. Jul, 2014  |   Pubmed ID: 24703889
• Viral Inoculum Dose Impacts Memory T-cell Inflation
  European Journal of Immunology. Apr, 2014  |   Pubmed ID: 24356925
• Local Immunomodulation for Cancer Therapy: Providing Treatment Where Needed
  Oncoimmunology. Nov, 2013  |   Pubmed ID: 24490127
• Nodular Inflammatory Foci Are Sites of T Cell Priming and Control of Murine Cytomegalovirus Infection in the Neonatal Lung
  PLoS Pathogens. 2013  |   Pubmed ID: 24348257
• The Distinct Role of T Cell Costimulation in Antiviral Immunity
  Current Opinion in Virology. Aug, 2013  |   Pubmed ID: 23850168
• Lysine Acetyltransferase PCAF is a Key Regulator of Arteriogenesis
  Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2013  |   Pubmed ID: 23788761
• Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-cell-dependent Tumor Eradication and Decreases Risk of Toxic Side Effects
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2013  |   Pubmed ID: 23788581
• Prospects of Combinatorial Synthetic Peptide Vaccine-based Immunotherapy Against Cancer
  Seminars in Immunology. Apr, 2013  |   Pubmed ID: 23706598
• CD27-CD70 Costimulation Controls T Cell Immunity During Acute and Persistent Cytomegalovirus Infection
  Journal of Virology. Jun, 2013  |   Pubmed ID: 23576505
• Predicting the Efficacy of Cancer Vaccines by Evaluating T-cell Responses
  Oncoimmunology. Jan, 2013  |   Pubmed ID: 23482345
• Vaccine-induced Effector-memory CD8+ T Cell Responses Predict Therapeutic Efficacy Against Tumors
  Journal of Immunology (Baltimore, Md. : 1950). Oct, 2012  |   Pubmed ID: 22914049
• Polyfunctional CD4+ T Cell Responses to Immunodominant Epitopes Correlate with Disease Activity of Virulent Salmonella
  PloS One. 2012  |   Pubmed ID: 22912884
• Rational Design of Vaccines: Learning from Immune Evasion Mechanisms of Persistent Viruses and Tumors
  Advances in Immunology. 2012  |   Pubmed ID: 22449784
• Local Activation of CD8 T Cells and Systemic Tumor Eradication Without Toxicity Via Slow Release and Local Delivery of Agonistic CD40 Antibody
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2011  |   Pubmed ID: 21389097
• Differential B7-CD28 Costimulatory Requirements for Stable and Inflationary Mouse Cytomegalovirus-specific Memory CD8 T Cell Populations
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2011  |   Pubmed ID: 21357256
• Immunotherapy for Persistent Viral Infections and Associated Disease
  Trends in Immunology. Mar, 2011  |   Pubmed ID: 21227751