Raymond R. Mattingly

Publications

• Angiotensin II-dependent Phosphorylation at Ser-11/Ser-18 and Ser-938 Shift the E2 Conformations of Rat Kidney Na,K-ATPase
  The Biochemical Journal. Dec, 2011  |   Pubmed ID: 22145807
• Aborted Autophagy and Nonapoptotic Death Induced by Farnesyl Transferase Inhibitor and Lovastatin
  The Journal of Pharmacology and Experimental Therapeutics. Apr, 2011  |   Pubmed ID: 21228063
• The Role of Neurofibromin in N-Ras Mediated AP-1 Regulation in Malignant Peripheral Nerve Sheath Tumors
  Molecular and Cellular Biochemistry. Nov, 2010  |   Pubmed ID: 20680410
• A Novel Geranylgeranyl Transferase Inhibitor in Combination with Lovastatin Inhibits Proliferation and Induces Autophagy in STS-26T MPNST Cells
  The Journal of Pharmacology and Experimental Therapeutics. Apr, 2010  |   Pubmed ID: 20086055
• Three-dimensional Overlay Culture Models of Human Breast Cancer Reveal a Critical Sensitivity to Mitogen-activated Protein Kinase Kinase Inhibitors
  The Journal of Pharmacology and Experimental Therapeutics. Mar, 2010  |   Pubmed ID: 19952304
• Working Together: Farnesyl Transferase Inhibitors and Statins Block Protein Prenylation
  Molecular and Cellular Pharmacology. Jan, 2009  |   Pubmed ID: 20419048
• Restoration of E-cadherin Cell-cell Junctions Requires Both Expression of E-cadherin and Suppression of ERK MAP Kinase Activation in Ras-transformed Breast Epithelial Cells
  Neoplasia (New York, N.Y.). Dec, 2008  |   Pubmed ID: 19048123
• Suppression of Proliferation of Two Independent NF1 Malignant Peripheral Nerve Sheath Tumor Cell Lines by the Pan-ErbB Inhibitor CI-1033
  Cancer Biology & Therapy. Dec, 2008  |   Pubmed ID: 18927496
• P21-Activated Kinase 1 Coordinates Aberrant Cell Survival and Pericellular Proteolysis in a Three-dimensional Culture Model for Premalignant Progression of Human Breast Cancer
  Neoplasia (New York, N.Y.). Apr, 2008  |   Pubmed ID: 18392133
• Induction of Apoptosis in Neurofibromatosis Type 1 Malignant Peripheral Nerve Sheath Tumor Cell Lines by a Combination of Novel Farnesyl Transferase Inhibitors and Lovastatin
  The Journal of Pharmacology and Experimental Therapeutics. Jul, 2008  |   Pubmed ID: 18367665
• Angiotensin II Stimulates Elution of Na-K-ATPase from a Digoxin-affinity Column by Increasing the Kinetic Response to Ligands That Trigger the Decay of E2-P
  American Journal of Physiology. Renal Physiology. Apr, 2008  |   Pubmed ID: 18272598
• Low and Nontoxic Inorganic Mercury Burdens Attenuate BCR-mediated Signal Transduction
  Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2007  |   Pubmed ID: 17656488
• Synthesis, Biochemical, and Cellular Evaluation of Farnesyl Monophosphate Prodrugs As Farnesyltransferase Inhibitors
  Journal of Medicinal Chemistry. Jul, 2007  |   Pubmed ID: 17555307
• Epac- and Rap- Independent ERK1/2 Phosphorylation Induced by Gs-coupled Receptor Stimulation in HEK293 Cells
  FEBS Letters. Jan, 2007  |   Pubmed ID: 17174312
• Molecular Targets for Emerging Anti-tumor Therapies for Neurofibromatosis Type 1
  Biochemical Pharmacology. Nov, 2006  |   Pubmed ID: 16797490
• The Ras-GRF1 Exchange Factor Coordinates Activation of H-Ras and Rac1 to Control Neuronal Morphology
  Molecular Biology of the Cell. May, 2006  |   Pubmed ID: 16481401
• Inorganic Mercury Inhibits the Activation of LAT in T-cell Receptor-mediated Signal Transduction
  Toxicological Sciences : an Official Journal of the Society of Toxicology. Jan, 2006  |   Pubmed ID: 16251484
• The Mitogen-activated Protein Kinase/extracellular Signal-regulated Kinase Kinase Inhibitor PD184352 (CI-1040) Selectively Induces Apoptosis in Malignant Schwannoma Cell Lines
  The Journal of Pharmacology and Experimental Therapeutics. Jan, 2006  |   Pubmed ID: 16239399
• Active P21-activated Kinase 1 Rescues MCF10A Breast Epithelial Cells from Undergoing Anoikis
  Neoplasia (New York, N.Y.). Jul, 2005  |   Pubmed ID: 16026643
• Endogenous Expression and Protein Kinase A-dependent Phosphorylation of the Guanine Nucleotide Exchange Factor Ras-GRF1 in Human Embryonic Kidney 293 Cells
  The FEBS Journal. May, 2005  |   Pubmed ID: 15853814
• Angiotensin II Directly Stimulates Activity and Alters the Phosphorylation of Na-K-ATPase in Rat Proximal Tubule with a Rapid Time Course
  American Journal of Physiology. Renal Physiology. Oct, 2004  |   Pubmed ID: 15161602
• TNF-alpha-mediated Apoptosis in Normal Human Prostate Epithelial Cells and Tumor Cell Lines
  Cancer Letters. Jan, 2004  |   Pubmed ID: 14732222
• Gbetagamma Subunits Stimulate P21-activated Kinase 1 (PAK1) Through Activation of PI3-kinase and Akt but Act Independently of Rac1/Cdc42
  FEBS Letters. Jan, 2004  |   Pubmed ID: 14706848
• Cell Surface Receptors Activate P21-activated Kinase 1 Via Multiple Ras and PI3-kinase-dependent Pathways
  Cellular Signalling. Dec, 2003  |   Pubmed ID: 14575865
• Mitogen-activated Protein Kinase Signaling in Drug-resistant Neuroblastoma Cells
  Methods in Molecular Biology (Clifton, N.J.). 2003  |   Pubmed ID: 12616713
• Phosphorylation of the Ras-GRF1 Exchange Factor at Ser916/898 Reveals Activation of Ras Signaling in the Cerebral Cortex
  The Journal of Biological Chemistry. Apr, 2003  |   Pubmed ID: 12538592
• Potent Suppression of Proliferation of A10 Vascular Smooth Muscle Cells by Combined Treatment with Lovastatin and 3-allylfarnesol, an Inhibitor of Protein Farnesyltransferase
  The Journal of Pharmacology and Experimental Therapeutics. Oct, 2002  |   Pubmed ID: 12235235
• Mechanism of 17-beta-estradiol-induced Erk1/2 Activation in Breast Cancer Cells. A Role for HER2 AND PKC-delta
  The Journal of Biological Chemistry. Jun, 2002  |   Pubmed ID: 11960991
• High RhoA Activity Maintains the Undifferentiated Mesenchymal Cell Phenotype, Whereas RhoA Down-regulation by Laminin-2 Induces Smooth Muscle Myogenesis
  The Journal of Cell Biology. Mar, 2002  |   Pubmed ID: 11877460