Reinis Vilskersts

Publications

• Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19
  International Journal of Molecular Sciences. Dec, 2021  |   Pubmed ID: 35008470
• Low Cardiac Content of Long-chain Acylcarnitines in TMLHE Knockout Mice Prevents Ischaemia-reperfusion-induced Mitochondrial and Cardiac Damage
  Free Radical Biology & Medicine. 12, 2021  |   Pubmed ID: 34728372
• Microbiota-Derived Metabolite Trimethylamine N-Oxide Protects Mitochondrial Energy Metabolism and Cardiac Functionality in a Rat Model of Right Ventricle Heart Failure
  Frontiers in Cell and Developmental Biology. 2020  |   Pubmed ID: 33520996
• Rats with Congenital Hydronephrosis Show Increased Susceptibility to Renal Ischemia-reperfusion Injury
  Physiological Reports. 11, 2020  |   Pubmed ID: 33207081
• Inhibition of CPT2 Exacerbates Cardiac Dysfunction and Inflammation in Experimental Endotoxaemia
  Journal of Cellular and Molecular Medicine. 10, 2020  |   Pubmed ID: 32896106
• 4-Pyridinio-1,4-Dihydropyridines As Calcium Ion Transport Modulators: Antagonist, Agonist, and Dual Action
  Oxidative Medicine and Cellular Longevity. 2020  |   Pubmed ID: 32308799
• Sulfonyl Group Dance: A Tool for the Synthesis of 6-Azido-2-sulfonylpurine Derivatives
  The Journal of Organic Chemistry. 04, 2020  |   Pubmed ID: 32150410
• Delivery Systems for Birch-bark Triterpenoids and Their Derivatives in Anticancer Research
  Current Medicinal Chemistry. 2020  |   Pubmed ID: 29848269
• Mitochondrial Function in the Kidney and Heart, but Not the Brain, is Mainly Altered in an Experimental Model of Endotoxaemia
  Shock (Augusta, Ga.). 12, 2019  |   Pubmed ID: 30640252
• Acute and Long-term Administration of Palmitoylcarnitine Induces Muscle-specific Insulin Resistance in Mice
  BioFactors (Oxford, England). Sep, 2017  |   Pubmed ID: 28759135
• Trimethylamine N-oxide Impairs Pyruvate and Fatty Acid Oxidation in Cardiac Mitochondria
  Toxicology Letters. Feb, 2017  |   Pubmed ID: 28049038
• Long-chain Acylcarnitines Determine Ischaemia/reperfusion-induced Damage in Heart Mitochondria
  The Biochemical Journal. 05, 2016  |   Pubmed ID: 26936967
• Pharmacological Effects of Meldonium: Biochemical Mechanisms and Biomarkers of Cardiometabolic Activity
  Pharmacological Research. 11, 2016  |   Pubmed ID: 26850121
• Methyl-γ-butyrobetaine Decreases Levels of Acylcarnitines and Attenuates the Development of Atherosclerosis
  Vascular Pharmacology. Sep, 2015  |   Pubmed ID: 25989106
• Selective Inhibition of OCTN2 is More Effective Than Inhibition of Gamma-butyrobetaine Dioxygenase to Decrease the Availability of L-carnitine and to Reduce Myocardial Infarct Size
  Pharmacological Research. Jul, 2014  |   Pubmed ID: 24836867
• Magnesium Nitrate Attenuates Blood Pressure Rise in SHR Rats
  Magnesium Research. Jan-Mar, 2014  |   Pubmed ID: 24827813
• The Heart is Better Protected Against Myocardial Infarction in the Fed State Compared to the Fasted State
  Metabolism: Clinical and Experimental. Jan, 2014  |   Pubmed ID: 24140100
• Elevated Vascular γ-butyrobetaine Levels Attenuate the Development of High Glucose-induced Endothelial Dysfunction
  Clinical and Experimental Pharmacology & Physiology. Aug, 2013  |   Pubmed ID: 23710938
• Synthesis and Biological Evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide Stereoisomers As Novel Positive Allosteric Modulators of Sigma-1 Receptor
  Bioorganic & Medicinal Chemistry. May, 2013  |   Pubmed ID: 23582449
• Glyoxalase 1 and Glyoxalase 2 Activities in Blood and Neuronal Tissue Samples from Experimental Animal Models of Obesity and Type 2 Diabetes Mellitus
  The Journal of Physiological Sciences : JPS. Nov, 2012  |   Pubmed ID: 22893478
• The Cardioprotective Effect of Mildronate is Diminished After Co-treatment with L-carnitine
  Journal of Cardiovascular Pharmacology and Therapeutics. Jun, 2012  |   Pubmed ID: 21903968
• Administration of L-carnitine and Mildronate Improves Endothelial Function and Decreases Mortality in Hypertensive Dahl Rats
  Pharmacological Reports : PR. 2011  |   Pubmed ID: 21857086
• The Anti-inflammatory and Antinociceptive Effects of NF-kappaB Inhibitory Guanidine Derivative ME10092
  International Immunopharmacology. Apr, 2010  |   Pubmed ID: 20074673
• Effects of Long-term Mildronate Treatment on Cardiac and Liver Functions in Rats
  Basic & Clinical Pharmacology & Toxicology. Dec, 2009  |   Pubmed ID: 19663820
• Protective Effects of Mildronate in an Experimental Model of Type 2 Diabetes in Goto-Kakizaki Rats
  British Journal of Pharmacology. Aug, 2009  |   Pubmed ID: 19594753
• Myocardial Infarct Size-limiting and Anti-arrhythmic Effects of Mildronate Orotate in the Rat Heart
  Cardiovascular Drugs and Therapy. Aug, 2009  |   Pubmed ID: 19536647
• Mildronate Decreases Carnitine Availability and Up-regulates Glucose Uptake and Related Gene Expression in the Mouse Heart
  Life Sciences. Oct, 2008  |   Pubmed ID: 18801379
• Mildronate, an Inhibitor of Carnitine Biosynthesis, Induces an Increase in Gamma-butyrobetaine Contents and Cardioprotection in Isolated Rat Heart Infarction
  Journal of Cardiovascular Pharmacology. Dec, 2006  |   Pubmed ID: 17204911