Rheal Towner Department of Chemistry University of Prince Edward Island Biography Publications Institution JoVE Articles Rheal Towner has not added a biography. If you are Rheal Towner and would like to personalize this page please email our Author Liaison for assistance. Publications Rapamycin Restores Brain Vasculature, Metabolism, and Blood-brain Barrier in an Inflammaging Model GeroScience. 04, 2021 | Pubmed ID: 33846885 ELTD1 As a Biomarker for Multiple Sclerosis: Pre-clinical Molecular-targeted Studies in a Mouse Experimental Autoimmune Encephalomyelitis Model Multiple Sclerosis and Related Disorders. Apr, 2021 | Pubmed ID: 33517175 OKlahoma Nitrone-007: Novel Treatment for Diffuse Intrinsic Pontine Glioma Journal of Translational Medicine. 11, 2020 | Pubmed ID: 33168005 Assessment of an ScFv Antibody Fragment Against ELTD1 in a G55 Glioblastoma Xenograft Model Translational Oncology. Mar, 2020 | Pubmed ID: 32208341 Anti-inflammatory Agent, OKN-007, Reverses Long-term Neuroinflammatory Responses in a Rat Encephalopathy Model As Assessed by Multi-parametric MRI: Implications for Aging-associated Neuroinflammation GeroScience. 08, 2019 | Pubmed ID: 31478121 Mechanics of the Tricuspid Valve-From Clinical Diagnosis/Treatment, In-Vivo and In-Vitro Investigations, to Patient-Specific Biomechanical Modeling Bioengineering (Basel, Switzerland). May, 2019 | Pubmed ID: 31121881 OKN-007 Increases Temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth Translational Oncology. Feb, 2019 | Pubmed ID: 30468988 Assessing Long-term Neuroinflammatory Responses to Encephalopathy Using MRI Approaches in a Rat Endotoxemia Model GeroScience. 02, 2018 | Pubmed ID: 29417380 A Feasibility Study to Determine Whether Clinical Contrast Enhanced Magnetic Resonance Imaging Can Detect Increased Bladder Permeability in Patients with Interstitial Cystitis The Journal of Urology. Mar, 2016 | Pubmed ID: 26307161 A New Anti-glioma Therapy, AG119: Pre-clinical Assessment in a Mouse GL261 Glioma Model BMC Cancer. Jul, 2015 | Pubmed ID: 26177924 OKN-007 Decreases Free Radical Levels in a Preclinical F98 Rat Glioma Model Free Radical Biology & Medicine. Oct, 2015 | Pubmed ID: 26119786 Contrast Enhanced Magnetic Resonance Imaging As a Diagnostic Tool to Assess Bladder Permeability and Associated Colon Cross Talk: Preclinical Studies in a Rat Model The Journal of Urology. Apr, 2015 | Pubmed ID: 25463988 Experimental Validation of 5 In-silico Predicted Glioma Biomarkers Neuro-oncology. Dec, 2013 | Pubmed ID: 24158112 In Vivo Detection of Free Radicals in Mouse Septic Encephalopathy Using Molecular MRI and Immuno-spin Trapping Free Radical Biology & Medicine. 12, 2013 | Pubmed ID: 23978375 Combined Molecular MRI and Immuno-spin-trapping for in Vivo Detection of Free Radicals in Orthotopic Mouse GL261 Gliomas Biochimica Et Biophysica Acta. Dec, 2013 | Pubmed ID: 23959048 In Vivo Detection of Free Radicals Using Molecular MRI and Immuno-spin Trapping in a Mouse Model for Amyotrophic Lateral Sclerosis Free Radical Biology & Medicine. Oct, 2013 | Pubmed ID: 23722162 Regression of Glioma Tumor Growth in F98 and U87 Rat Glioma Models by the Nitrone OKN-007 Neuro-oncology. Mar, 2013 | Pubmed ID: 23328810 ELTD1, a Potential New Biomarker for Gliomas Neurosurgery. Jan, 2013 | Pubmed ID: 23096411 In Vivo Imaging of Immuno-spin Trapped Radicals with Molecular Magnetic Resonance Imaging in a Diabetic Mouse Model Diabetes. Oct, 2012 | Pubmed ID: 22698922 In Vivo Detection of Inducible Nitric Oxide Synthase in Rodent Gliomas Free Radical Biology & Medicine. Mar, 2010 | Pubmed ID: 20034558 Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy Michael G. Melek1, Rheal Towner2,3, Johannes Kung1, Debra Saunders4, Michelle Zales3,4, Faizah Bhatti1,3 1Department of Pediatrics, University of Oklahoma Health Sciences Center, 2Department of Chemistry, University of Prince Edward Island, 3Center for Neuroscience, University of Oklahoma Health Sciences Center, 4Oklahoma Medical Research Foundation JoVE 64183 Medicine
Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy Michael G. Melek1, Rheal Towner2,3, Johannes Kung1, Debra Saunders4, Michelle Zales3,4, Faizah Bhatti1,3 1Department of Pediatrics, University of Oklahoma Health Sciences Center, 2Department of Chemistry, University of Prince Edward Island, 3Center for Neuroscience, University of Oklahoma Health Sciences Center, 4Oklahoma Medical Research Foundation JoVE 64183 Medicine
