Richard A Van Etten

Publications

• Essential Role for Stat5a/b in Myeloproliferative Neoplasms Induced by BCR-ABL1 and Jak2V617F in Mice
  Blood. Jan, 2012  |   Pubmed ID: 22234689
• Distinct Graft-versus-leukemic Stem Cell Effects of Early or Delayed Donor Leukocyte Infusions in a Mouse Chronic Myeloid Leukemia Model
  Blood. Jan, 2012  |   Pubmed ID: 22072555
• Targeting CXCR4 with Cell-penetrating Pepducins in Lymphoma and Lymphocytic Leukemia
  Blood. Dec, 2011  |   Pubmed ID: 22186993
• Comparison of MRNA and Lentiviral Based Transfection of Natural Killer Cells with Chimeric Antigen Receptors Recognizing Lymphoid Antigens
  Leukemia & Lymphoma. Dec, 2011  |   Pubmed ID: 22023526
• Chronic Myeloid Leukemia 2011: Successes, Challenges, and Strategies--proceedings of the 5th Annual BCR-ABL1 Positive and BCR-ABL1 Negative Myeloproliferative Neoplasms Workshop
  American Journal of Hematology. Sep, 2011  |   Pubmed ID: 21850662
• BCL6: a Novel Target for Therapy of Ph+ B Cell Acute Lymphoblastic Leukemia
  Cancer Cell. Jul, 2011  |   Pubmed ID: 21741592
• CDK6 Kinase Activity is Required for Thymocyte Development
  Blood. Jun, 2011  |   Pubmed ID: 21508411
• Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-control Inhibitor DCC-2036
  Cancer Cell. Apr, 2011  |   Pubmed ID: 21481795
• Navigating the Road Toward Optimal Initial Therapy for Chronic Myeloid Leukemia
  Current Opinion in Hematology. Mar, 2011  |   Pubmed ID: 21252655
• The Ph-positive and Ph-negative Myeloproliferative Neoplasms: Some Topical Pre-clinical and Clinical Issues
  Haematologica. Apr, 2011  |   Pubmed ID: 21242185
• Targeting Autophagy Potentiates Tyrosine Kinase Inhibitor-induced Cell Death in Philadelphia Chromosome-positive Cells, Including Primary CML Stem Cells
  The Journal of Clinical Investigation. May, 2009  |   Pubmed ID: 19363292
• GCK is Essential to Systemic Inflammation and Pattern Recognition Receptor Signaling to JNK and P38
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009  |   Pubmed ID: 19246396
• Murine Retroviral Bone Marrow Transplantation Models for the Study of Human Myeloproliferative Disorders
  Current Protocols in Pharmacology / Editorial Board, S.J. Enna (editor-in-chief) ... [et Al.]. Dec, 2008  |   Pubmed ID: 22294220
• Suppression of E-protein Activity Interferes with the Development of BCR-ABL-mediated Myeloproliferative Disease
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008  |   Pubmed ID: 18725623
• Peroxiredoxin1 Prevents Excessive Endothelial Activation and Early Atherosclerosis
  Circulation Research. Sep, 2008  |   Pubmed ID: 18689572
• Bedside to Bench: Interfering with Leukemic Stem Cells
  Nature Medicine. May, 2008  |   Pubmed ID: 18463658
• Right on Target: Eradicating Leukemic Stem Cells
  Trends in Molecular Medicine. Nov, 2007  |   Pubmed ID: 17981087
• Molecular Mechanisms of Cardiotoxicity of Tyrosine Kinase Inhibition
  Nature Reviews. Cancer. May, 2007  |   Pubmed ID: 17457301
• Oncogenic Signaling: New Insights and Controversies from Chronic Myeloid Leukemia
  The Journal of Experimental Medicine. Mar, 2007  |   Pubmed ID: 17353369
• Ubiquitous and Uniform in Vivo Fluorescence in ROSA26-EGFP BAC Transgenic Mice
  Genesis (New York, N.Y. : 2000). Feb, 2007  |   Pubmed ID: 17269129
• Molecular Pathogenesis and Therapy of Polycythemia Induced in Mice by JAK2 V617F
  PloS One. 2006  |   Pubmed ID: 17183644
• Requirement for CD44 in Homing and Engraftment of BCR-ABL-expressing Leukemic Stem Cells
  Nature Medicine. Oct, 2006  |   Pubmed ID: 16998483
• Cardiotoxicity of the Cancer Therapeutic Agent Imatinib Mesylate
  Nature Medicine. Aug, 2006  |   Pubmed ID: 16862153
• Tyrosine Kinases As Targets for Cancer Therapy
  The New England Journal of Medicine. Jul, 2005  |   Pubmed ID: 16014887
• Tyrosine 394 is Phosphorylated in Alzheimer's Paired Helical Filament Tau and in Fetal Tau with C-Abl As the Candidate Tyrosine Kinase
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2005  |   Pubmed ID: 16014719
• JAKing Up Hematopoietic Proliferation
  Cancer Cell. Apr, 2005  |   Pubmed ID: 15837617
• Imatinib Mesylate Radiosensitizes Human Glioblastoma Cells Through Inhibition of Platelet-derived Growth Factor Receptor
  Blood Cells, Molecules & Diseases. Mar-Apr, 2005  |   Pubmed ID: 15727903
• Focus on Myeloproliferative Diseases and Myelodysplastic Syndromes
  Cancer Cell. Dec, 2004  |   Pubmed ID: 15607959
• Adoptive Immunotherapy of BCR-ABL-induced Chronic Myeloid Leukemia-like Myeloproliferative Disease in a Murine Model
  Blood. Dec, 2004  |   Pubmed ID: 15308567
• A Direct Binding Site for Grb2 Contributes to Transformation and Leukemogenesis by the Tel-Abl (ETV6-Abl) Tyrosine Kinase
  Molecular and Cellular Biology. Jun, 2004  |   Pubmed ID: 15143164
• Requirement of Src Kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic Leukemia but Not Chronic Myeloid Leukemia
  Nature Genetics. May, 2004  |   Pubmed ID: 15098032
• Distinct Stem Cell Myeloproliferative/T Lymphoma Syndromes Induced by ZNF198-FGFR1 and BCR-FGFR1 Fusion Genes from 8p11 Translocations
  Cancer Cell. Mar, 2004  |   Pubmed ID: 15050920
• Mechanisms of Transformation by the BCR-ABL Oncogene: New Perspectives in the Post-imatinib Era
  Leukemia Research. May, 2004  |   Pubmed ID: 15036938
• C-Abl Regulation: a Tail of Two Lipids
  Current Biology : CB. Aug, 2003  |   Pubmed ID: 12906815
• Essential Role for the Peroxiredoxin Prdx1 in Erythrocyte Antioxidant Defence and Tumour Suppression
  Nature. Jul, 2003  |   Pubmed ID: 12891360
• Autoinhibition of Bcr-Abl Through Its SH3 Domain
  Molecular Cell. Jul, 2003  |   Pubmed ID: 12887890
• Studying the Pathogenesis of BCR-ABL+ Leukemia in Mice
  Oncogene. Dec, 2002  |   Pubmed ID: 12476310
• Clinical Resistance to the Kinase Inhibitor STI-571 in Chronic Myeloid Leukemia by Mutation of Tyr-253 in the Abl Kinase Domain P-loop
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2002  |   Pubmed ID: 12149456
• Critical Role for Gab2 in Transformation by BCR/ABL
  Cancer Cell. Jun, 2002  |   Pubmed ID: 12124177
• Tyrosine Phosphorylation of Mdm2 by C-Abl: Implications for P53 Regulation
  The EMBO Journal. Jul, 2002  |   Pubmed ID: 12110584
• The Tel-Abl (ETV6-Abl) Tyrosine Kinase, Product of Complex (9;12) Translocations in Human Leukemia, Induces Distinct Myeloproliferative Disease in Mice
  Blood. Jun, 2002  |   Pubmed ID: 12036890
• A Murine Model of CML Blast Crisis Induced by Cooperation Between BCR/ABL and NUP98/HOXA9
  Proceedings of the National Academy of Sciences of the United States of America. May, 2002  |   Pubmed ID: 12032333