Richard I. Christopherson School of Molecular Bioscience University of Sydney Biography Publications Institution JoVE Articles Richard I. Christopherson has not added a biography. If you are Richard I. Christopherson and would like to personalize this page please email our Author Liaison for assistance. Publications The Phosphoinositide 3-kinase Inhibitor LY294002, Decreases Aminoacyl-tRNA Synthetases, Chaperones and Glycolytic Enzymes in Human HT-29 Colorectal Cancer Cells Journal of Proteomics. Feb, 2012 | Pubmed ID: 22172953 The Hsp90 Inhibitor SNX-7081 Synergizes with and Restores Sensitivity to Fludarabine in Chronic Lymphocytic Leukemia Cells with Lesions in the TP53 Pathway: a Potential Treatment Strategy for Fludarabine Refractory Disease Leukemia & Lymphoma. Jan, 2012 | Pubmed ID: 22149137 Biomarkers of Breast Cancer Apoptosis Induced by Chemotherapy and TRAIL Journal of Proteome Research. Feb, 2012 | Pubmed ID: 22133146 Surface Profiles for Sub-classification of Chronic Lymphocytic Leukemia Leukemia & Lymphoma. Oct, 2011 | Pubmed ID: 22023531 Comprehensive Proteomic Analysis of the Effects of Purine Analogs on Human Raji B-cell Lymphoma Journal of Proteome Research. Mar, 2011 | Pubmed ID: 21182289 Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders International Journal of Proteomics. 2010 | Pubmed ID: 22084681 Cell Surface Markers in Colorectal Cancer Prognosis International Journal of Molecular Sciences. 2010 | Pubmed ID: 21339979 An Extended Antibody Microarray for Surface Profiling Metastatic Melanoma Journal of Immunological Methods. Jun, 2010 | Pubmed ID: 20363224 Surface Antigen Profiling of Colorectal Cancer Using Antibody Microarrays with Fluorescence Multiplexing Journal of Immunological Methods. Apr, 2010 | Pubmed ID: 20156443 Membrane Proteomics for Leukemia Classification and Drug Target Identification Current Opinion in Molecular Therapeutics. Dec, 2009 | Pubmed ID: 20072937 Profiling CD Antigens on Leukaemias with an Antibody Microarray FEBS Letters. Jun, 2009 | Pubmed ID: 19298816 The Applicability of a Cluster of Differentiation Monoclonal Antibody Microarray to the Diagnosis of Human Disease Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370105 Structure and Inhibition of Orotidine 5'-monophosphate Decarboxylase from Plasmodium Falciparum Biochemistry. Mar, 2008 | Pubmed ID: 18303855 All-trans Retinoic Acid Induces Different Immunophenotypic Changes on Human HL60 and NB4 Myeloid Leukaemias Leukemia Research. Feb, 2008 | Pubmed ID: 17561254 Differentially Expressed Nuclear Proteins in Human CCRF-CEM, HL-60, MEC-1 and Raji Cells Correlate with Cellular Properties Proteomics. Clinical Applications. Oct, 2007 | Pubmed ID: 21136623 Profiling of Apoptotic Changes in Human Breast Cancer Cells Using SELDI-TOF Mass Spectrometry Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2007 | Pubmed ID: 17762184 Kinetic and Structural Analysis of Mutant Escherichia Coli Dihydroorotases: a Flexible Loop Stabilizes the Transition State Biochemistry. Sep, 2007 | Pubmed ID: 17711307 Differentially Expressed Cytosolic Proteins in Human Leukemia and Lymphoma Cell Lines Correlate with Lineages and Functions Biochimica Et Biophysica Acta. Sep, 2007 | Pubmed ID: 17698427 Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia Coli: Implications for Loop Movement in Inhibitor Design Journal of Molecular Biology. Jul, 2007 | Pubmed ID: 17550785 The Nuclear Proteome and DNA-binding Fraction of Human Raji Lymphoma Cells Biochimica Et Biophysica Acta. Apr, 2007 | Pubmed ID: 17369005 Analysis of Human Leukaemias and Lymphomas Using Extensive Immunophenotypes from an Antibody Microarray British Journal of Haematology. Oct, 2006 | Pubmed ID: 16939496 The Application of CD Antigen Proteomics to Pharmacogenomics Pharmacogenomics. Jul, 2006 | Pubmed ID: 16886900 Thermodynamic Analysis of Catalysis by the Dihydroorotases from Hamster and Bacillus Caldolyticus, As Compared with the Uncatalyzed Reaction Biochemistry. Jul, 2006 | Pubmed ID: 16819826 13C and 15N Isotope Effects for Conversion of L-dihydroorotate to N-carbamyl-L-aspartate Using Dihydroorotase from Hamster and Bacillus Caldolyticus Biochemistry. Jun, 2006 | Pubmed ID: 16752903 Classification of AML Using a Monoclonal Antibody Microarray Methods in Molecular Medicine. 2006 | Pubmed ID: 16502589 Multiplex Detection of Surface Molecules on Colorectal Cancers Proteomics. Mar, 2006 | Pubmed ID: 16485257 Screening Microarrays of Novel Monoclonal Antibodies for Binding to T-, B- and Myeloid Leukaemia Cells Journal of Immunological Methods. Oct, 2005 | Pubmed ID: 16125720 Human Epidermal and Monocyte-derived Langerhans Cells Express Functional P2X Receptors The Journal of Investigative Dermatology. Sep, 2005 | Pubmed ID: 16117789 Immunophenotypic Changes Induced on Human HL60 Leukaemia Cells by 1alpha,25-dihydroxyvitamin D3 and 12-O-tetradecanoyl Phorbol-13-acetate Leukemia Research. Oct, 2005 | Pubmed ID: 16111532 Conservation of Unique Cell-surface CD Antigen Mosaics in HIV-1-infected Individuals Blood. Aug, 2005 | Pubmed ID: 15827132 Dihydroorotase from Escherichia Coli: Loop Movement and Cooperativity Between Subunits Journal of Molecular Biology. May, 2005 | Pubmed ID: 15826651 Metabolic Response Patterns of Nucleotides in B-cell Chronic Lymphocytic Leukaemias to Cladribine, Fludarabine and Deoxycoformycin Leukemia Research. Jul, 2004 | Pubmed ID: 15158094 Identification of Repertoires of Surface Antigens on Leukemias Using an Antibody Microarray Proteomics. Nov, 2003 | Pubmed ID: 14595814 Crystallization of Hamster Dihydroorotase: Involvement of a Disulfide-linked Tetrameric Form Acta Crystallographica. Section D, Biological Crystallography. Feb, 2003 | Pubmed ID: 12554960 Antibody Arrays: an Embryonic but Rapidly Growing Technology Drug Discovery Today. Sep, 2002 | Pubmed ID: 12546881 Inhibitors of De Novo Nucleotide Biosynthesis As Drugs Accounts of Chemical Research. Nov, 2002 | Pubmed ID: 12437321 Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing Jerry Zhou1, Larissa Belov1, Michael J. Solomon2, Charles Chan3, Stephen J. Clarke4, Richard I. Christopherson1 1School of Molecular Bioscience, University of Sydney, 2Department of Surgery, Royal Prince Alfred Hospital, 3Department of Anatomical Pathology, Department of Anatomical Pathology, 4Department of Medicine, Concord Repatriation General Hospital JoVE 3322 Immunology and Infection
Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing Jerry Zhou1, Larissa Belov1, Michael J. Solomon2, Charles Chan3, Stephen J. Clarke4, Richard I. Christopherson1 1School of Molecular Bioscience, University of Sydney, 2Department of Surgery, Royal Prince Alfred Hospital, 3Department of Anatomical Pathology, Department of Anatomical Pathology, 4Department of Medicine, Concord Repatriation General Hospital JoVE 3322 Immunology and Infection
