Richard Francis

Publications

• Red Blood Cell Components: Meeting the Quantitative and Qualitative Transfusion Needs
  Presse Medicale (Paris, France : 1983). Jul, 2016  |   Pubmed ID: 27476016
• Attitudes in 2013 to Monitoring Intracranial Pressure for Traumatic Intracerebral Haemorrhage
  Acta Neurochirurgica. Supplement. 2016  |   Pubmed ID: 27165869
• Diagnosis of a Rare Fetal Haemoglobinopathy in the Age of Next-generation Sequencing
  BMJ Case Reports. 2016  |   Pubmed ID: 27095814
• Reference Genotype and Exome Data from an Australian Aboriginal Population for Health-based Research
  Scientific Data. 2016  |   Pubmed ID: 27070114
• DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia
  PLoS Genetics. Feb, 2016  |   Pubmed ID: 26918822
• ViPAR: a Software Platform for the Virtual Pooling and Analysis of Research Data
  International Journal of Epidemiology. Oct, 2015  |   Pubmed ID: 26452388
• Discovery of Four Recessive Developmental Disorders Using Probabilistic Genotype and Phenotype Matching Among 4,125 Families
  Nature Genetics. Nov, 2015  |   Pubmed ID: 26437029
• Characteristics of Traumatic Intracerebral Haemorrhage: An Assessment of Screening Logs from the STITCH(Trauma) Trial
  British Journal of Neurosurgery. 2015  |   Pubmed ID: 26414559
• Surgical Trial In Traumatic IntraCerebral Haemorrhage (STITCH): a Randomised Controlled Trial of Early Surgery Compared with Initial Conservative Treatment
  Health Technology Assessment (Winchester, England). Sep, 2015  |   Pubmed ID: 26346805
• Automated Identification of Abnormal Respiratory Ciliary Motion in Nasal Biopsies
  Science Translational Medicine. Aug, 2015  |   Pubmed ID: 26246169
• G6PD Deficiency in an HIV Clinic Setting in the Dominican Republic
  The American Journal of Tropical Medicine and Hygiene. Oct, 2015  |   Pubmed ID: 26240158
• Red Blood Cell Transfusion is Associated with Increased Hemolysis and an Acute Phase Response in a Subset of Critically Ill Children
  American Journal of Hematology. Oct, 2015  |   Pubmed ID: 26183122
• Distribution of Raphespinal Fibers in the Mouse Spinal Cord
  Molecular Pain. 2015  |   Pubmed ID: 26173454
• The Future of Host Cell Protein (HCP) Identification During Process Development and Manufacturing Linked to a Risk-based Management for Their Control
  Biotechnology and Bioengineering. Sep, 2015  |   Pubmed ID: 25998019
• Novel Jbts17 Mutant Mouse Model of Joubert Syndrome with Cilia Transition Zone Defects and Cerebellar and Other Ciliopathy Related Anomalies
  Human Molecular Genetics. Jul, 2015  |   Pubmed ID: 25877302
• Global Genetic Analysis in Mice Unveils Central Role for Cilia in Congenital Heart Disease
  Nature. May, 2015  |   Pubmed ID: 25807483
• First Genome-wide Association Study in an Australian Aboriginal Population Provides Insights into Genetic Risk Factors for Body Mass Index and Type 2 Diabetes
  PloS One. 2015  |   Pubmed ID: 25760438
• Early Surgery Versus Initial Conservative Treatment in Patients with Traumatic Intracerebral Hemorrhage (STITCH[Trauma]): The First Randomized Trial
  Journal of Neurotrauma. Sep, 2015  |   Pubmed ID: 25738794
• Dexmedetomidine and Fentanyl Exhibit Temperature Dependent Effects on Human Respiratory Cilia
  Frontiers in Pediatrics. 2015  |   Pubmed ID: 25717467
• ANKS6 is the Critical Activator of NEK8 Kinase in Embryonic Situs Determination and Organ Patterning
  Nature Communications. 2015  |   Pubmed ID: 25599650
• Decellularized Tracheal Extracellular Matrix Supports Epithelial Migration, Differentiation, and Function
  Tissue Engineering. Part A. Jan, 2015  |   Pubmed ID: 24980864
• IFT27 Links the BBSome to IFT for Maintenance of the Ciliary Signaling Compartment
  Developmental Cell. Nov, 2014  |   Pubmed ID: 25446516
• The Effects of Temperature and Anesthetic Agents on Ciliary Function in Murine Respiratory Epithelia
  Frontiers in Pediatrics. 2014  |   Pubmed ID: 25360434
• Airway Ciliary Dysfunction and Sinopulmonary Symptoms in Patients with Congenital Heart Disease
  Annals of the American Thoracic Society. Nov, 2014  |   Pubmed ID: 25302410
• Marine Geophysics. New Global Marine Gravity Model from CryoSat-2 and Jason-1 Reveals Buried Tectonic Structure
  Science (New York, N.Y.). Oct, 2014  |   Pubmed ID: 25278606
• DataSHIELD: Taking the Analysis to the Data, Not the Data to the Analysis
  International Journal of Epidemiology. Dec, 2014  |   Pubmed ID: 25261970
• Methaemoglobinaemia and Haemolysis Following Pegloticase Infusion for Refractory Gout in a Patient with a Falsely Negative Glucose-6-phosphate Dehydrogenase Deficiency Result
  Rheumatology (Oxford, England). Dec, 2014  |   Pubmed ID: 25224415
• Macrophages Clear Refrigerator Storage-damaged Red Blood Cells and Subsequently Secrete Cytokines in Vivo, but Not in Vitro, in a Murine Model
  Transfusion. Dec, 2014  |   Pubmed ID: 25041478
• Transfusion of Stored Blood Impairs Host Defenses Against Gram-negative Pathogens in Mice
  Transfusion. May, 2014  |   Pubmed ID: 24840185
• A Comparison of Adverse Reaction Rates for PAS C Versus Plasma Platelet Units
  Transfusion. Aug, 2014  |   Pubmed ID: 24735171
• Genetic and Functional Evidence for a Locus Controlling Otitis Media at Chromosome 10q26.3
  BMC Medical Genetics. 2014  |   Pubmed ID: 24499112
• Attitudes to Intracranial Pressure Monitoring of Traumatic Intracerebral Haemorrhage
  British Journal of Neurosurgery. Oct, 2014  |   Pubmed ID: 24479704
• Interrogating Congenital Heart Defects with Noninvasive Fetal Echocardiography in a Mouse Forward Genetic Screen
  Circulation. Cardiovascular Imaging. Jan, 2014  |   Pubmed ID: 24319090
• Ion Torrent Sequencing for Conducting Genome-wide Scans for Mutation Mapping Analysis
  Mammalian Genome : Official Journal of the International Mammalian Genome Society. Apr, 2014  |   Pubmed ID: 24306492
• GOLink: Finding Cooccurring Terms Across Gene Ontology Namespaces
  International Journal of Genomics. 2013  |   Pubmed ID: 24524070
• Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton
  PLoS Biology. Nov, 2013  |   Pubmed ID: 24302887
• Imaging Techniques for Visualizing and Phenotyping Congenital Heart Defects in Murine Models
  Birth Defects Research. Part C, Embryo Today : Reviews. Jun, 2013  |   Pubmed ID: 23897594
• Increased Postoperative Respiratory Complications in Heterotaxy Congenital Heart Disease Patients with Respiratory Ciliary Dysfunction
  The Journal of Thoracic and Cardiovascular Surgery. Jul, 2013  |   Pubmed ID: 23886032
• DYX1C1 is Required for Axonemal Dynein Assembly and Ciliary Motility
  Nature Genetics. Jul, 2013  |   Pubmed ID: 23872636
• The Ability of an Arginine to Tryptophan Substitution in Saccharomyces Cerevisiae TRNA Nucleotidyltransferase to Alleviate a Temperature-sensitive Phenotype Suggests a Role for Motif C in Active Site Organization
  Biochimica Et Biophysica Acta. Oct, 2013  |   Pubmed ID: 23872483
• ARMC4 Mutations Cause Primary Ciliary Dyskinesia with Randomization of Left/Right Body Asymmetry
  American Journal of Human Genetics. Jul, 2013  |   Pubmed ID: 23849778
• Microcomputed Tomography Provides High Accuracy Congenital Heart Disease Diagnosis in Neonatal and Fetal Mice
  Circulation. Cardiovascular Imaging. Jul, 2013  |   Pubmed ID: 23759365
• Strain-specific Red Blood Cell Storage, Metabolism, and Eicosanoid Generation in a Mouse Model
  Transfusion. May, 2013  |   Pubmed ID: 23721209
• The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends
  Journal of Autism and Developmental Disorders. Apr, 2013  |   Pubmed ID: 23563868
• The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions During Autophagy
  Developmental Cell. Apr, 2013  |   Pubmed ID: 23562278
• Genetic and Functional Evidence for a Role for SLC11A1 in Susceptibility to Otitis Media in Early Childhood in a Western Australian Population
  Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. Jun, 2013  |   Pubmed ID: 23538334
• Acquired Hemoglobin Variants and Exposure to Glucose-6-phosphate Dehydrogenase Deficient Red Blood Cell Units During Exchange Transfusion for Sickle Cell Disease in a Patient Requiring Antigen-matched Blood
  Journal of Clinical Apheresis. Mar, 2013  |   Pubmed ID: 23450789
• Frequency of Glucose-6-phosphate Dehydrogenase-deficient Red Blood Cell Units in a Metropolitan Transfusion Service
  Transfusion. Mar, 2013  |   Pubmed ID: 22738400
• TENS (transcutaneous Electrical Nerve Stimulation) for Labour Pain
  The Practising Midwife. May, 2012  |   Pubmed ID: 22788003
• FusionFinder: a Software Tool to Identify Expressed Gene Fusion Candidates from RNA-Seq Data
  PloS One. 2012  |   Pubmed ID: 22761941
• High Prevalence of Respiratory Ciliary Dysfunction in Congenital Heart Disease Patients with Heterotaxy
  Circulation. May, 2012  |   Pubmed ID: 22499950
• West Nile Virus Infection in Blood Donors in the New York City Area During the 2010 Seasonal Epidemic
  Transfusion. Dec, 2012  |   Pubmed ID: 22486471
• Rapid Detection of Klebsiella Pneumoniae Carbapenemase Genes in Enterobacteriaceae Directly from Blood Culture Bottles by Real-time PCR
  American Journal of Clinical Pathology. Apr, 2012  |   Pubmed ID: 22431540
• Congenital Heart Disease and the Specification of Left-right Asymmetry
  American Journal of Physiology. Heart and Circulatory Physiology. May, 2012  |   Pubmed ID: 22408017
• The Characteristics of Acupuncture-like Transcutaneous Electrical Nerve Stimulation (acupuncture-like TENS): a Literature Review
  Acupuncture & Electro-therapeutics Research. 2011  |   Pubmed ID: 22443026
• Traumatic Intracerebral Hemorrhage--to Operate or Not?
  World Neurosurgery. Dec, 2011  |   Pubmed ID: 22251488
• Connexin43 Modulates Cell Polarity and Directional Cell Migration by Regulating Microtubule Dynamics
  PloS One. 2011  |   Pubmed ID: 22022608
• Transfusion of Human Volunteers with Older, Stored Red Blood Cells Produces Extravascular Hemolysis and Circulating Non-transferrin-bound Iron
  Blood. Dec, 2011  |   Pubmed ID: 22021369
• Comparison of Post-treatment Effects of Conventional and Acupuncture-like Transcutaneous Electrical Nerve Stimulation (TENS): A Randomised Placebo-controlled Study Using Cold-induced Pain and Healthy Human Participants
  Physiotherapy Theory and Practice. Nov, 2011  |   Pubmed ID: 22007892
• Conventional Versus Acupuncture-like Transcutaneous Electrical Nerve Stimulation on Cold-induced Pain in Healthy Human Participants: Effects During Stimulation
  Clinical Physiology and Functional Imaging. Sep, 2011  |   Pubmed ID: 21771255
• Genetic and Functional Evidence Implicating DLL1 As the Gene That Influences Susceptibility to Visceral Leishmaniasis at Chromosome 6q27
  The Journal of Infectious Diseases. Aug, 2011  |   Pubmed ID: 21742847
• Comparison of Post-treatment Effects of Conventional and Acupuncture-like Transcutaneous Electrical Nerve Stimulation (TENS): A Randomised Placebo-controlled Study Using Cold-induced Pain and Healthy Human Participants
  Physiotherapy Theory and Practice. Jul, 2011  |   Pubmed ID: 21721994
• Predominance of Nontypeable Haemophilus Influenzae in Children with Otitis Media Following Introduction of a 3+0 Pneumococcal Conjugate Vaccine Schedule
  Vaccine. Jul, 2011  |   Pubmed ID: 21621576
• Disruption of Mks1 Localization to the Mother Centriole Causes Cilia Defects and Developmental Malformations in Meckel-Gruber Syndrome
  Disease Models & Mechanisms. Jan, 2011  |   Pubmed ID: 21045211
• Classification and Regression Tree and Spatial Analyses Reveal Geographic Heterogeneity in Genome Wide Linkage Study of Indian Visceral Leishmaniasis
  PloS One. 2010  |   Pubmed ID: 21209823
• An Automated Packed Protein G Micro-pipette Tip Assay for Rapid Quantification of Polyclonal Antibodies in Ovine Serum
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Nov, 2010  |   Pubmed ID: 20951101
• Validation of a Mouse Xenograft Model System for Gene Expression Analysis of Human Acute Lymphoblastic Leukaemia
  BMC Genomics. 2010  |   Pubmed ID: 20406497
• La Transfusión De Glóbulos Rojos Tras Un Almacenamiento Prolongado Produce Efectos Nocivos Que Están Mediadas Por Hierro Y La Inflamación
  Blood. May, 2010  |   Pubmed ID: 20299509
• A Screen for Endocytic Motifs
  Traffic (Copenhagen, Denmark). Jun, 2010  |   Pubmed ID: 20214754
• Armus is a Rac1 Effector That Inactivates Rab7 and Regulates E-cadherin Degradation
  Current Biology : CB. Feb, 2010  |   Pubmed ID: 20116244
• Ventricular Rotation is Independent of Cardiac Looping: a Study in Mice with Situs Inversus Totalis Using Speckle-tracking Echocardiography
  Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Mar, 2010  |   Pubmed ID: 20097527
• Conexina 43 Regula La Polaridad De La Célula Epicárdica Y Migración En El Desarrollo Vascular Coronaria
  Development (Cambridge, England). Sep, 2009  |   Pubmed ID: 19700622
• FoxM1 is a Downstream Target and Marker of HER2 Overexpression in Breast Cancer
  International Journal of Oncology. Jul, 2009  |   Pubmed ID: 19513552
• Initiation and Maturation of Cilia-generated Flow in Newborn and Postnatal Mouse Airway
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2009  |   Pubmed ID: 19346437
• Gefitinib (Iressa) Represses FOXM1 Expression Via FOXO3a in Breast Cancer
  Molecular Cancer Therapeutics. Mar, 2009  |   Pubmed ID: 19276163
• Massively Parallel Sequencing Identifies the Gene Megf8 with ENU-induced Mutation Causing Heterotaxy
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009  |   Pubmed ID: 19218456
• Murine CENPF Interacts with Syntaxin 4 in the Regulation of Vesicular Transport
  Journal of Cell Science. Oct, 2008  |   Pubmed ID: 18827011
• The D Subunit Plays a Central Role in Human Vacuolar H(+)-ATPases
  Journal of Bioenergetics and Biomembranes. Aug, 2008  |   Pubmed ID: 18752060
• Doxorubicin Activates FOXO3a to Induce the Expression of Multidrug Resistance Gene ABCB1 (MDR1) in K562 Leukemic Cells
  Molecular Cancer Therapeutics. Mar, 2008  |   Pubmed ID: 18347152
• Global Sensitivity Analysis for the Determination of Parameter Importance in Bio-manufacturing Processes
  Biotechnology and Applied Biochemistry. Oct, 2008  |   Pubmed ID: 18205624
• Modelo De Ratón De Heterotaxia Con Espectro De Ventrículo único De Anomalías Cardiacas
  Pediatric Research. Jan, 2008  |   Pubmed ID: 18043505
• The Transcription Factor FOXO3a is a Crucial Cellular Target of Gefitinib (Iressa) in Breast Cancer Cells
  Molecular Cancer Therapeutics. Dec, 2007  |   Pubmed ID: 18089711
• Heterotaxia Y Defectos Estructurales Complejos Del Corazón En Un Modelo De Ratón Mutante De La Discinesia Ciliar Primaria
  The Journal of Clinical Investigation. Dec, 2007  |   Pubmed ID: 18037990
• Evaluation of a Novel Agarose-based Synthetic Ligand Adsorbent for the Recovery of Antibodies from Ovine Serum
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Dec, 2007  |   Pubmed ID: 18024245
• Evolution of Differences in Transport Function in Slc11a Family Members
  The Journal of Biological Chemistry. Dec, 2007  |   Pubmed ID: 17932044
• A Prototype Software Methodology for the Rapid Evaluation of Biomanufacturing Process Options
  Biotechnology and Applied Biochemistry. Oct, 2007  |   Pubmed ID: 17868020
• Decision-support Software for the Industrial-scale Chromatographic Purification of Antibodies
  Biotechnology Progress. Jul-Aug, 2007  |   Pubmed ID: 17630695
• Detection and Quantification of Affinity Ligand Leaching and Specific Antibody Fragment Concentration Within Chromatographic Fractions Using Surface Plasmon Resonance
  Biotechnology and Applied Biochemistry. Dec, 2007  |   Pubmed ID: 17516918
• Multipotent Hematopoietic Cells Susceptible to Alternative Double-strand Break Repair Pathways That Promote Genome Rearrangements
  Genes & Development. May, 2007  |   Pubmed ID: 17473170
• TCF7L2 Polymorphisms Modulate Proinsulin Levels and Beta-cell Function in a British Europid Population
  Diabetes. Jul, 2007  |   Pubmed ID: 17416797
• Rb Induces a Proliferative Arrest and Curtails Brn-2 Expression in Retinoblastoma Cells
  Molecular Cancer. 2006  |   Pubmed ID: 17163992
• The Integrated Simulation and Assessment of the Impacts of Process Change in Biotherapeutic Antibody Production
  Biotechnology Progress. Nov-Dec, 2006  |   Pubmed ID: 17137309
• Connexin 43-mediated Modulation of Polarized Cell Movement and the Directional Migration of Cardiac Neural Crest Cells
  Development (Cambridge, England). Sep, 2006  |   Pubmed ID: 16914489
• Primordial Germ Cell Deficiency in the Connexin 43 Knockout Mouse Arises from Apoptosis Associated with Abnormal P53 Activation
  Development (Cambridge, England). Sep, 2006  |   Pubmed ID: 16887824
• The Forkhead Box M1 Protein Regulates the Transcription of the Estrogen Receptor Alpha in Breast Cancer Cells
  The Journal of Biological Chemistry. Sep, 2006  |   Pubmed ID: 16809346
• From Genome to Vaccines for Leishmaniasis: Screening 100 Novel Vaccine Candidates Against Murine Leishmania Major Infection
  Vaccine. Mar, 2006  |   Pubmed ID: 16406227
• It's a Puzzle All Right: the Hippocampus and Food Hoarding
  Trends in Ecology & Evolution. Sep, 2005  |   Pubmed ID: 16701422
• Application of a Decision-support Tool to Assess Pooling Strategies in Perfusion Culture Processes Under Uncertainty
  Biotechnology Progress. Jul-Aug, 2005  |   Pubmed ID: 16080707
• Optimal Conditions for the Papain Digestion of Polyclonal Ovine IgG for the Production of Bio-therapeutic Fab Fragments
  Biotechnology and Applied Biochemistry. Oct, 2005  |   Pubmed ID: 15799716
• Connexin43 Associated with an N-cadherin-containing Multiprotein Complex is Required for Gap Junction Formation in NIH3T3 Cells
  The Journal of Biological Chemistry. May, 2005  |   Pubmed ID: 15741167
• Optimised Affinity Purification of Polyclonal Antibodies from Hyper Immunised Ovine Serum Using a Synthetic Protein A Adsorbent, MAbsorbent A2P
  Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Jan, 2005  |   Pubmed ID: 15639441
• Separation of Immunoglobulin G Precipitate from Contaminating Proteins Using Microfiltration
  Biotechnology and Applied Biochemistry. Apr, 2004  |   Pubmed ID: 15032745
• Shared Scheme for Assessing Drugs for Multiple Sclerosis: Cost Effective Provision of Effective Treatments for Multiple Sclerosis
  BMJ (Clinical Research Ed.). May, 2003  |   Pubmed ID: 12775633
• Changes in Activin and Activin Receptor Subunit Expression in Rat Liver During the Development of CCl4-induced Cirrhosis
  Molecular and Cellular Endocrinology. Mar, 2003  |   Pubmed ID: 12706302
• Evaluation and Management of Scoliosis
  Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners. Jan-Feb, 2003  |   Pubmed ID: 12533733
• P107 and P130 Coordinately Regulate Proliferation, Cbfa1 Expression, and Hypertrophic Differentiation During Endochondral Bone Development
  Developmental Biology. Jul, 2002  |   Pubmed ID: 12086466
• Endothelin Receptor A Blockade Ameliorates Hypothermic Ischemia-reperfusion-related Microhemodynamic Disturbances During Liver Transplantation in the Rat
  The Journal of Surgical Research. Feb, 2002  |   Pubmed ID: 11796000