Rob Krams Department of Bioengineering Imperial College London Biography Publications Institution JoVE Articles Rob Krams has not added a biography. If you are Rob Krams and would like to personalize this page please email our Author Liaison for assistance. Publications Kissing Balloon or Sequential Dilation of the Side Branch and Main Vessel for Provisional Stenting of Bifurcations: Lessons from Micro-computed Tomography and Computational Simulations JACC. Cardiovascular Interventions. Jan, 2012 | Pubmed ID: 22230150 Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans International Journal of Inflammation. 2011 | Pubmed ID: 22164344 Final Proximal Post-dilatation is Necessary After Kissing Balloon in Bifurcation Stenting EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. Sep, 2011 | Pubmed ID: 21930464 Jailed Side Branches: Fate of Unapposed Struts Studied with 3D Frequency-domain Optical Coherence Tomography Journal of Cardiovascular Medicine (Hagerstown, Md.). Aug, 2011 | Pubmed ID: 21709576 Stabilisation of Atherosclerotic Plaques. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology Thrombosis and Haemostasis. Jul, 2011 | Pubmed ID: 21670845 Disturbed Blood Flow Induces RelA Expression Via C-Jun N-terminal Kinase 1: a Novel Mode of NF-κB Regulation That Promotes Arterial Inflammation Circulation Research. Apr, 2011 | Pubmed ID: 21350211 Dexamethasone Arterializes Venous Endothelial Cells by Inducing Mitogen-activated Protein Kinase Phosphatase-1: a Novel Antiinflammatory Treatment for Vein Grafts? Circulation. Feb, 2011 | Pubmed ID: 21262999 Contrast Enhancement by Differently Sized Paramagnetic MRI Contrast Agents in Mice with Two Phenotypes of Atherosclerotic Plaque Contrast Media & Molecular Imaging. Jan-Feb, 2011 | Pubmed ID: 20882509 Microcalcifications in Atherosclerotic Lesion of Apolipoprotein E-deficient Mouse International Journal of Experimental Pathology. Dec, 2010 | Pubmed ID: 20804542 Flow Interactions with Cells and Tissues: Cardiovascular Flows and Fluid-structure Interactions. Sixth International Bio-Fluid Mechanics Symposium and Workshop, March 28-30, 2008, Pasadena, California Annals of Biomedical Engineering. Mar, 2010 | Pubmed ID: 20336826 MRI-determined Carotid Artery Flow Velocities and Wall Shear Stress in a Mouse Model of Vulnerable and Stable Atherosclerotic Plaque Magma (New York, N.Y.). Apr, 2010 | Pubmed ID: 20229088 C-Jun N-terminal Kinase Primes Endothelial Cells at Atheroprone Sites for Apoptosis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2010 | Pubmed ID: 20056910 Activation of Nrf2 in Endothelial Cells Protects Arteries from Exhibiting a Proinflammatory State Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2009 | Pubmed ID: 19729611 Activation of MMP8 and MMP13 by Angiotensin II Correlates to Severe Intra-plaque Hemorrhages and Collagen Breakdown in Atherosclerotic Lesions with a Vulnerable Phenotype Atherosclerosis. May, 2009 | Pubmed ID: 19233360 Donor Pre-treatment with Tacrolimus Reduces Transplant Vasculopathy Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Apr, 2009 | Pubmed ID: 19162189 Large Variations in Absolute Wall Shear Stress Levels Within One Species and Between Species Atherosclerosis. May, 2009 | Pubmed ID: 18823888 A Primer on the Immune System in the Pathogenesis and Treatment of Atherosclerosis EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. Nov, 2008 | Pubmed ID: 19110813 Personalised Imaging and Biomechanical Modelling of Large Vessels Medical & Biological Engineering & Computing. Nov, 2008 | Pubmed ID: 18987903 Pulmonary Artery Size and Function After Fontan Operation at a Young Age Journal of Magnetic Resonance Imaging : JMRI. Nov, 2008 | Pubmed ID: 18972351 Atherosclerosis: Cell Biology and Lipoproteins--shear Stress and Inflammation in Plaque Formation: New Evidence Current Opinion in Lipidology. Dec, 2008 | Pubmed ID: 18957888 Hemodynamic Parameters Regulating Vascular Inflammation and Atherosclerosis: a Brief Update Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie. Oct, 2008 | Pubmed ID: 18757166 Increased Endothelial Mitogen-activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis Circulation Research. Sep, 2008 | Pubmed ID: 18723442 Atherosclerosis: Cell Biology and Lipoproteins - New Developments in Imaging of Inflammation of the Vulnerable Plaque Current Opinion in Lipidology. Feb, 2008 | Pubmed ID: 18196994 Rapamycin Modulates the ENOS Vs. Shear Stress Relationship Cardiovascular Research. Apr, 2008 | Pubmed ID: 18079107 Endothelial Primary Cilia in Areas of Disturbed Flow Are at the Base of Atherosclerosis Atherosclerosis. Feb, 2008 | Pubmed ID: 17631294 Effect of Shear Stress on Vascular Inflammation and Plaque Development Current Opinion in Lipidology. Oct, 2007 | Pubmed ID: 17885423 Assessment of Unstable Atherosclerosis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2007 | Pubmed ID: 17332492 Shear Stress-induced Changes in Atherosclerotic Plaque Composition Are Modulated by Chemokines The Journal of Clinical Investigation. Mar, 2007 | Pubmed ID: 17304353 Gelatinolytic Activity in Atherosclerotic Plaques is Highly Localized and is Associated with Both Macrophages and Smooth Muscle Cells in Vivo Circulation. Feb, 2007 | Pubmed ID: 17242283 Large Variations in Absolute Wall Shear Stress Levels Within One Species and Between Species Atherosclerosis. Dec, 2007 | Pubmed ID: 17169362 Harmonic Intravascular Ultrasound Imaging with a Dual-frequency Catheter Ultrasound in Medicine & Biology. Nov, 2006 | Pubmed ID: 17112951 Intravascular Ultrasound Tissue Harmonic Imaging in Vivo IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Oct, 2006 | Pubmed ID: 17036792 Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress Circulation. Jun, 2006 | Pubmed ID: 16754802 Norepinephrine-induced Vasoconstriction Results in Decreased Blood Volume in Dialysis Patients Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. May, 2006 | Pubmed ID: 16449290 Three-dimensional Palpography of Human Coronary Arteries. Ex Vivo Validation and In-patient Evaluation Herz. Mar, 2005 | Pubmed ID: 16493546 In Vivo Temperature Heterogeneity is Associated with Plaque Regions of Increased MMP-9 Activity European Heart Journal. Oct, 2005 | Pubmed ID: 16144779 Myocardial Contractility Does Not Determine the Haemodynamic Response During Dialysis Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Nov, 2005 | Pubmed ID: 16115849 Shear Stress Affects the Intracellular Distribution of ENOS: Direct Demonstration by a Novel in Vivo Technique Blood. Dec, 2005 | Pubmed ID: 16105973 Geometry Guided Data Averaging Enables the Interpretation of Shear Stress Related Plaque Development in Human Coronary Arteries Journal of Biomechanics. Jul, 2005 | Pubmed ID: 15922767 Letter Regarding Article by Korshunov and Berk, "Strain-dependent Vascular Remodeling: the 'Glagov Phenomenon' is Genetically Determined" Circulation. Mar, 2005 | Pubmed ID: 15753223 The Role of Shear Stress in Atherosclerosis: Action Through Gene Expression and Inflammation? Cell Biochemistry and Biophysics. 2004 | Pubmed ID: 15475614 Diastolic Coronary Vascular Reserve: a New Index to Detect Changes in the Coronary Microcirculation in Hypertrophic Cardiomyopathy Journal of the American College of Cardiology. Feb, 2004 | Pubmed ID: 14975481 Intravascular Thermography: Immediate Functional and Morphological Vascular Findings European Heart Journal. Jan, 2004 | Pubmed ID: 14720533 The Effect of Reduced Blood-flow on the Coronary Wall Temperature. Are Significant Lesions Suitable for Intravascular Thermography? European Heart Journal. Oct, 2003 | Pubmed ID: 14522575 Functional Expression of Endothelial Nitric Oxide Synthase Fused to Green Fluorescent Protein in Transgenic Mice The American Journal of Pathology. Oct, 2003 | Pubmed ID: 14507674 Extension of Increased Atherosclerotic Wall Thickness into High Shear Stress Regions is Associated with Loss of Compensatory Remodeling Circulation. Jul, 2003 | Pubmed ID: 12821552 Inflammation and Atherosclerosis: Mechanisms Underlying Vulnerable Plaque Journal of Interventional Cardiology. Apr, 2003 | Pubmed ID: 12768913 Augmentation of Wall Shear Stress Inhibits Neointimal Hyperplasia After Stent Implantation: Inhibition Through Reduction of Inflammation? Circulation. Jun, 2003 | Pubmed ID: 12742998 Shear Stress, Vascular Remodeling and Neointimal Formation Journal of Biomechanics. May, 2003 | Pubmed ID: 12694998 High Shear Stress After Successful Balloon Angioplasty is Associated with Restenosis and Target Lesion Revascularization American Heart Journal. Jul, 2002 | Pubmed ID: 12094200 Images in Cardiovascular Medicine. Focal In-stent Restenosis Near Step-up: Roles of Low and Oscillating Shear Stress? Circulation. Jun, 2002 | Pubmed ID: 12057999 Calcium Sensitizer EMD 57033, but Not the Beta1-adrenoreceptor Agonist Dobutamine, Increases Mechanical Efficiency in Stunned Myocardium Journal of Cardiovascular Pharmacology. Jan, 2002 | Pubmed ID: 11743229 Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice Michael T. Kuhlmann1, Simon Cuhlmann2,3, Irmgard Hoppe1, Rob Krams3, Paul C. Evans2, Gustav J. Strijkers4, Klaas Nicolay4, Sven Hermann1, Michael Schäfers1 1European Institute for Molecular Imaging, Westfälische Wilhelms-University Münster, 2British Heart Foundation Cardiovascular Sciences Unit, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Biomedical Engineering, Eindhoven University of Technology JoVE 3308 Medicine
Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice Michael T. Kuhlmann1, Simon Cuhlmann2,3, Irmgard Hoppe1, Rob Krams3, Paul C. Evans2, Gustav J. Strijkers4, Klaas Nicolay4, Sven Hermann1, Michael Schäfers1 1European Institute for Molecular Imaging, Westfälische Wilhelms-University Münster, 2British Heart Foundation Cardiovascular Sciences Unit, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Biomedical Engineering, Eindhoven University of Technology JoVE 3308 Medicine