Robert A. Winn Department of Pulmonary, Critical Care, Sleep, and Allergy University of Illinois at Chicago Biography Publications Institution JoVE Articles Robert A. Winn has not added a biography. If you are Robert A. Winn and would like to personalize this page please email our Author Liaison for assistance. Publications Heterotrimeric G-protein, Gα16, is a Critical Downstream Effector of Non-canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer PloS One. 2013 | Pubmed ID: 24204697 Hsa-miR29b, a Critical Downstream Target of Non-canonical Wnt Signaling, Plays an Anti-proliferative Role in Non-small Cell Lung Cancer Cells Via Targeting MDM2 Expression Biology Open. Jul, 2013 | Pubmed ID: 23862015 Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2013 | Pubmed ID: 23757356 Non-small-cell Lung Cancer: Molecular Targeted Therapy and Personalized Medicine - Drug Resistance, Mechanisms, and Strategies Pharmacogenomics and Personalized Medicine. 2013 | Pubmed ID: 23690695 Dishevelled3 is a Novel Arginine Methyl Transferase Substrate Scientific Reports. 2012 | Pubmed ID: 23150776 Stromal Cell-derived Factor 1α Mediates Resistance to MTOR-directed Therapy in Pancreatic Cancer Neoplasia (New York, N.Y.). Aug, 2012 | Pubmed ID: 22952422 Methylation of Wnt7a is Modulated by DNMT1 and Cigarette Smoke Condensate in Non-small Cell Lung Cancer PloS One. 2012 | Pubmed ID: 22403725 The Many Faces of Wnt and Pancreatic Ductal adenocarcinoma Oncogenesis Cancers. 2011 | Pubmed ID: 24212973 "Un-slugging" Resistance to Epidermal Growth Factor Receptor Inhibition. A Positive Outlook for the Future of Lung Cancer Therapy American Journal of Respiratory and Critical Care Medicine. Apr, 2011 | Pubmed ID: 21498821 Sprouty-4 Inhibits Transformed Cell Growth, Migration and Invasion, and Epithelial-mesenchymal Transition, and is Regulated by Wnt7A Through PPARgamma in Non-small Cell Lung Cancer Molecular Cancer Research : MCR. Jun, 2010 | Pubmed ID: 20501643 Prostacyclin Inhibits Non-small Cell Lung Cancer Growth by a Frizzled 9-dependent Pathway That is Blocked by Secreted Frizzled-related Protein 1 Neoplasia (New York, N.Y.). Mar, 2010 | Pubmed ID: 20234818 Peroxisome Proliferator-activated Receptor-gamma Inhibits Transformed Growth of Non-small Cell Lung Cancer Cells Through Selective Suppression of Snail Neoplasia (New York, N.Y.). Mar, 2010 | Pubmed ID: 20234816 The Role of Prostacyclin in Lung Cancer Translational Research : the Journal of Laboratory and Clinical Medicine. Feb, 2010 | Pubmed ID: 20129485 Depletion of Cytosolic Phospholipase A2 in Bone Marrow-derived Macrophages Protects Against Lung Cancer Progression and Metastasis Cancer Research. Mar, 2009 | Pubmed ID: 19208832 Oncogenic K-Ras Regulates Proliferation and Cell Junctions in Lung Epithelial Cells Through Induction of Cyclooxygenase-2 and Activation of Metalloproteinase-9 Molecular Biology of the Cell. Feb, 2009 | Pubmed ID: 19037103 Prostacyclin Prevents Murine Lung Cancer Independent of the Membrane Receptor by Activation of Peroxisomal Proliferator--activated Receptor Gamma Cancer Prevention Research (Philadelphia, Pa.). Oct, 2008 | Pubmed ID: 19138979 Analysis of Wnt7a-stimulated JNK Activity and CJun Phosphorylation in Non-small Cell Lung Cancer Cells Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 19099255 The Cancer Paradigm of Severe Pulmonary Arterial Hypertension American Journal of Respiratory and Critical Care Medicine. Sep, 2008 | Pubmed ID: 18556624 Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-gamma Ligands in Lung Cancer PPAR Research. 2008 | Pubmed ID: 18509496 Wnt Signaling Pathway and Lung Disease Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2008 | Pubmed ID: 18355764 Antitumorigenic Effects of Peroxisome Proliferator-activated Receptor-gamma in Non-small-cell Lung Cancer Cells Are Mediated by Suppression of Cyclooxygenase-2 Via Inhibition of Nuclear Factor-kappaB Molecular Pharmacology. Mar, 2008 | Pubmed ID: 18055759 Role of the Wnt Signaling Pathway and Lung Cancer Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Oct, 2007 | Pubmed ID: 17909349 Antitumorigenic Effect of Wnt 7a and Fzd 9 in Non-small Cell Lung Cancer Cells is Mediated Through ERK-5-dependent Activation of Peroxisome Proliferator-activated Receptor Gamma The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16835228 Beta-catenin in the Fibroproliferative Response to Acute Lung Injury American Journal of Respiratory Cell and Molecular Biology. Mar, 2006 | Pubmed ID: 16272459 Inhibited Neurogenesis in JNK1-deficient Embryonic Stem Cells Molecular and Cellular Biology. Dec, 2005 | Pubmed ID: 16314504 Role of Nuclear Receptors in Lung Tumourigenesis European Journal of Cancer (Oxford, England : 1990). Nov, 2005 | Pubmed ID: 16199155 A Middle-aged Woman with Recurrent Respiratory Infections Respiration; International Review of Thoracic Diseases. Jul-Aug, 2005 | Pubmed ID: 16088289 Restoration of Wnt-7a Expression Reverses Non-small Cell Lung Cancer Cellular Transformation Through Frizzled-9-mediated Growth Inhibition and Promotion of Cell Differentiation The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15705594 Dysphagia, Chest Pain, and Refractory Asthma in a 42-year-old Woman Chest. Nov, 2004 | Pubmed ID: 15539746 Gamma-catenin Expression is Reduced or Absent in a Subset of Human Non-small Cell Lung Cancers, and Its Re-expression Inhibits Cell Growth Chest. May, 2004 | Pubmed ID: 15136458 Multiple Pulmonary Nodules in an HIV-positive Man on Highly Active Antiretroviral Therapy Chest. Nov, 2002 | Pubmed ID: 12426290 Peroxisome Proliferator-activated Receptor-gamma is a Target of Nonsteroidal Anti-inflammatory Drugs Mediating Cyclooxygenase-independent Inhibition of Lung Cancer Cell Growth Molecular Pharmacology. Nov, 2002 | Pubmed ID: 12391285 Gamma-Catenin Expression is Reduced or Absent in a Subset of Human Lung Cancers and Re-expression Inhibits Transformed Cell Growth Oncogene. Oct, 2002 | Pubmed ID: 12386812 Soft Agar Colony Formation Assay Stanley Borowicz1, Michelle Van Scoyk2, Sreedevi Avasarala2, Manoj Kumar Karuppusamy Rathinam2, Jordi Tauler2, Rama Kamesh Bikkavilli2, Robert A. Winn2,3 1Department of Hematology and Oncology, University of Illinois at Chicago, 2Department of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 3Jesse Brown Veterans Affairs Medical Center Biology In vitro Methylering Assay til at studere protein Arginin Methylering Rama Kamesh Bikkavilli1, Sreedevi Avasarala1, Michelle Van Scoyk1, Manoj Kumar Karuppusamy Rathinam1, Jordi Tauler1, Stanley Borowicz1,2, Robert A. Winn1,3 1Department of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 2Department of Hematology and Oncology, University of Illinois at Chicago, 3Jesse Brown Veterans Affairs Medical Center JoVE 51997 Biology
Soft Agar Colony Formation Assay Stanley Borowicz1, Michelle Van Scoyk2, Sreedevi Avasarala2, Manoj Kumar Karuppusamy Rathinam2, Jordi Tauler2, Rama Kamesh Bikkavilli2, Robert A. Winn2,3 1Department of Hematology and Oncology, University of Illinois at Chicago, 2Department of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 3Jesse Brown Veterans Affairs Medical Center Biology
In vitro Methylering Assay til at studere protein Arginin Methylering Rama Kamesh Bikkavilli1, Sreedevi Avasarala1, Michelle Van Scoyk1, Manoj Kumar Karuppusamy Rathinam1, Jordi Tauler1, Stanley Borowicz1,2, Robert A. Winn1,3 1Department of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 2Department of Hematology and Oncology, University of Illinois at Chicago, 3Jesse Brown Veterans Affairs Medical Center JoVE 51997 Biology
