Robert A. Winn

Publications

• Heterotrimeric G-protein, Gα16, is a Critical Downstream Effector of Non-canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer
  PloS One. 2013  |   Pubmed ID: 24204697
• Hsa-miR29b, a Critical Downstream Target of Non-canonical Wnt Signaling, Plays an Anti-proliferative Role in Non-small Cell Lung Cancer Cells Via Targeting MDM2 Expression
  Biology Open. Jul, 2013  |   Pubmed ID: 23862015
• Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2013  |   Pubmed ID: 23757356
• Non-small-cell Lung Cancer: Molecular Targeted Therapy and Personalized Medicine - Drug Resistance, Mechanisms, and Strategies
  Pharmacogenomics and Personalized Medicine. 2013  |   Pubmed ID: 23690695
• Dishevelled3 is a Novel Arginine Methyl Transferase Substrate
  Scientific Reports. 2012  |   Pubmed ID: 23150776
• Stromal Cell-derived Factor 1α Mediates Resistance to MTOR-directed Therapy in Pancreatic Cancer
  Neoplasia (New York, N.Y.). Aug, 2012  |   Pubmed ID: 22952422
• Methylation of Wnt7a is Modulated by DNMT1 and Cigarette Smoke Condensate in Non-small Cell Lung Cancer
  PloS One. 2012  |   Pubmed ID: 22403725
• The Many Faces of Wnt and Pancreatic Ductal adenocarcinoma Oncogenesis
  Cancers. 2011  |   Pubmed ID: 24212973
• "Un-slugging" Resistance to Epidermal Growth Factor Receptor Inhibition. A Positive Outlook for the Future of Lung Cancer Therapy
  American Journal of Respiratory and Critical Care Medicine. Apr, 2011  |   Pubmed ID: 21498821
• Sprouty-4 Inhibits Transformed Cell Growth, Migration and Invasion, and Epithelial-mesenchymal Transition, and is Regulated by Wnt7A Through PPARgamma in Non-small Cell Lung Cancer
  Molecular Cancer Research : MCR. Jun, 2010  |   Pubmed ID: 20501643
• Prostacyclin Inhibits Non-small Cell Lung Cancer Growth by a Frizzled 9-dependent Pathway That is Blocked by Secreted Frizzled-related Protein 1
  Neoplasia (New York, N.Y.). Mar, 2010  |   Pubmed ID: 20234818
• Peroxisome Proliferator-activated Receptor-gamma Inhibits Transformed Growth of Non-small Cell Lung Cancer Cells Through Selective Suppression of Snail
  Neoplasia (New York, N.Y.). Mar, 2010  |   Pubmed ID: 20234816
• The Role of Prostacyclin in Lung Cancer
  Translational Research : the Journal of Laboratory and Clinical Medicine. Feb, 2010  |   Pubmed ID: 20129485
• Depletion of Cytosolic Phospholipase A2 in Bone Marrow-derived Macrophages Protects Against Lung Cancer Progression and Metastasis
  Cancer Research. Mar, 2009  |   Pubmed ID: 19208832
• Oncogenic K-Ras Regulates Proliferation and Cell Junctions in Lung Epithelial Cells Through Induction of Cyclooxygenase-2 and Activation of Metalloproteinase-9
  Molecular Biology of the Cell. Feb, 2009  |   Pubmed ID: 19037103
• Prostacyclin Prevents Murine Lung Cancer Independent of the Membrane Receptor by Activation of Peroxisomal Proliferator--activated Receptor Gamma
  Cancer Prevention Research (Philadelphia, Pa.). Oct, 2008  |   Pubmed ID: 19138979
• Analysis of Wnt7a-stimulated JNK Activity and CJun Phosphorylation in Non-small Cell Lung Cancer Cells
  Methods in Molecular Biology (Clifton, N.J.). 2008  |   Pubmed ID: 19099255
• The Cancer Paradigm of Severe Pulmonary Arterial Hypertension
  American Journal of Respiratory and Critical Care Medicine. Sep, 2008  |   Pubmed ID: 18556624
• Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-gamma Ligands in Lung Cancer
  PPAR Research. 2008  |   Pubmed ID: 18509496
• Wnt Signaling Pathway and Lung Disease
  Translational Research : the Journal of Laboratory and Clinical Medicine. Apr, 2008  |   Pubmed ID: 18355764
• Antitumorigenic Effects of Peroxisome Proliferator-activated Receptor-gamma in Non-small-cell Lung Cancer Cells Are Mediated by Suppression of Cyclooxygenase-2 Via Inhibition of Nuclear Factor-kappaB
  Molecular Pharmacology. Mar, 2008  |   Pubmed ID: 18055759
• Role of the Wnt Signaling Pathway and Lung Cancer
  Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Oct, 2007  |   Pubmed ID: 17909349
• Antitumorigenic Effect of Wnt 7a and Fzd 9 in Non-small Cell Lung Cancer Cells is Mediated Through ERK-5-dependent Activation of Peroxisome Proliferator-activated Receptor Gamma
  The Journal of Biological Chemistry. Sep, 2006  |   Pubmed ID: 16835228
• Beta-catenin in the Fibroproliferative Response to Acute Lung Injury
  American Journal of Respiratory Cell and Molecular Biology. Mar, 2006  |   Pubmed ID: 16272459
• Inhibited Neurogenesis in JNK1-deficient Embryonic Stem Cells
  Molecular and Cellular Biology. Dec, 2005  |   Pubmed ID: 16314504
• Role of Nuclear Receptors in Lung Tumourigenesis
  European Journal of Cancer (Oxford, England : 1990). Nov, 2005  |   Pubmed ID: 16199155
• A Middle-aged Woman with Recurrent Respiratory Infections
  Respiration; International Review of Thoracic Diseases. Jul-Aug, 2005  |   Pubmed ID: 16088289
• Restoration of Wnt-7a Expression Reverses Non-small Cell Lung Cancer Cellular Transformation Through Frizzled-9-mediated Growth Inhibition and Promotion of Cell Differentiation
  The Journal of Biological Chemistry. May, 2005  |   Pubmed ID: 15705594
• Dysphagia, Chest Pain, and Refractory Asthma in a 42-year-old Woman
  Chest. Nov, 2004  |   Pubmed ID: 15539746
• Gamma-catenin Expression is Reduced or Absent in a Subset of Human Non-small Cell Lung Cancers, and Its Re-expression Inhibits Cell Growth
  Chest. May, 2004  |   Pubmed ID: 15136458
• Multiple Pulmonary Nodules in an HIV-positive Man on Highly Active Antiretroviral Therapy
  Chest. Nov, 2002  |   Pubmed ID: 12426290
• Peroxisome Proliferator-activated Receptor-gamma is a Target of Nonsteroidal Anti-inflammatory Drugs Mediating Cyclooxygenase-independent Inhibition of Lung Cancer Cell Growth
  Molecular Pharmacology. Nov, 2002  |   Pubmed ID: 12391285
• Gamma-Catenin Expression is Reduced or Absent in a Subset of Human Lung Cancers and Re-expression Inhibits Transformed Cell Growth
  Oncogene. Oct, 2002  |   Pubmed ID: 12386812