Robert H. Edwards

Publications

• Dopamine Dysregulation in a Mouse Model of Paroxysmal Nonkinesigenic Dyskinesia
  The Journal of Clinical Investigation. Feb, 2012  |   Pubmed ID: 22214848
• Vesicular and Plasma Membrane Transporters for Neurotransmitters
  Cold Spring Harbor Perspectives in Biology. 2012  |   Pubmed ID: 22199021
• Neurotransmitter Corelease: Mechanism and Physiological Role
  Annual Review of Physiology. Mar, 2012  |   Pubmed ID: 22054239
• Presynaptic Regulation of Quantal Size: K+/H+ Exchange Stimulates Vesicular Glutamate Transport
  Nature Neuroscience. Oct, 2011  |   Pubmed ID: 21874016
• Genetic Targeting and Physiological Features of VGLUT3+ Amacrine Cells
  Visual Neuroscience. Sep, 2011  |   Pubmed ID: 21864449
• V-SNARE Composition Distinguishes Synaptic Vesicle Pools
  Neuron. Aug, 2011  |   Pubmed ID: 21835344
• Expression of Vesicular Glutamate Transporters Type 1 and 2 in Sensory and Autonomic Neurons Innervating the Mouse Colorectum
  The Journal of Comparative Neurology. Nov, 2011  |   Pubmed ID: 21800314
• Pathway-specific Genetic Attenuation of Glutamate Release Alters Select Features of Competition-based Visual Circuit Refinement
  Neuron. Jul, 2011  |   Pubmed ID: 21791283
• Cholinergic Interneurons Mediate Fast VGluT3-dependent Glutamatergic Transmission in the Striatum
  PloS One. 2011  |   Pubmed ID: 21544206
• Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein Alpha-synuclein
  The Journal of Biological Chemistry. Jun, 2011  |   Pubmed ID: 21489994
• RNAi Screen Identifies a Role for Adaptor Protein AP-3 in Sorting to the Regulated Secretory Pathway
  The Journal of Cell Biology. Dec, 2010  |   Pubmed ID: 21149569
• VGLUT2 Expression in Primary Afferent Neurons is Essential for Normal Acute Pain and Injury-induced Heat Hypersensitivity
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010  |   Pubmed ID: 21135246
• Metabolic Control of Vesicular Glutamate Transport and Release
  Neuron. Oct, 2010  |   Pubmed ID: 20920794
• Dopaminergic Terminals in the Nucleus Accumbens but Not the Dorsal Striatum Corelease Glutamate
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010  |   Pubmed ID: 20554874
• Vesicular Monoamine and Glutamate Transporters Select Distinct Synaptic Vesicle Recycling Pathways
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2010  |   Pubmed ID: 20534840
• Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease in Vivo
  Neuron. Mar, 2010  |   Pubmed ID: 20223200
• The Behavior of Alpha-synuclein in Neurons
  Movement Disorders : Official Journal of the Movement Disorder Society. 2010  |   Pubmed ID: 20187244
• Increased Expression of Alpha-synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering After Endocytosis
  Neuron. Jan, 2010  |   Pubmed ID: 20152114
• Localized Topological Changes of the Plasma Membrane Upon Exocytosis Visualized by Polarized TIRFM
  The Journal of Cell Biology. Feb, 2010  |   Pubmed ID: 20142424
• Glutamate Co-release at GABA/glycinergic Synapses is Crucial for the Refinement of an Inhibitory Map
  Nature Neuroscience. Feb, 2010  |   Pubmed ID: 20081852
• Injury-induced Mechanical Hypersensitivity Requires C-low Threshold Mechanoreceptors
  Nature. Dec, 2009  |   Pubmed ID: 19915548
• Fluorescent False Neurotransmitters Visualize Dopamine Release from Individual Presynaptic Terminals
  Science (New York, N.Y.). Jun, 2009  |   Pubmed ID: 19423778
• Synaptic and Extrasynaptic Factors Governing Glutamatergic Retinal Waves
  Neuron. Apr, 2009  |   Pubmed ID: 19409268
• Interplay Between Cytosolic Dopamine, Calcium, and Alpha-synuclein Causes Selective Death of Substantia Nigra Neurons
  Neuron. Apr, 2009  |   Pubmed ID: 19409267
• Vesicular Glutamate and GABA Transporters Sort to Distinct Sets of Vesicles in a Population of Presynaptic Terminals
  Cerebral Cortex (New York, N.Y. : 1991). Jan, 2009  |   Pubmed ID: 18502731
• Optical Reporters for the Conformation of Alpha-synuclein Reveal a Specific Interaction with Mitochondria
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008  |   Pubmed ID: 19020024
• Fast Subplasma Membrane Ca2+ Transients Control Exo-endocytosis of Synaptic-like Microvesicles in Astrocytes
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2008  |   Pubmed ID: 18784293
• Vesicular Glutamate Transporter 3-immunoreactive Pericellular Baskets Ensheath a Distinct Population of Neurons in the Lateral Septum
  Journal of Chemical Neuroanatomy. Dec, 2008  |   Pubmed ID: 18611437
• Expression and Function of the Rat Vesicular Monoamine Transporter 2
  American Journal of Physiology. Cell Physiology. Apr, 2008  |   Pubmed ID: 18287335
• Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3
  Neuron. Jan, 2008  |   Pubmed ID: 18215623
• Pharmacology of Neurotransmitter Transport into Secretory Vesicles
  Handbook of Experimental Pharmacology. 2008  |   Pubmed ID: 18064412
• Vesicular Neurotransmitter Transporters As Targets for Endogenous and Exogenous Toxic Substances
  Annual Review of Pharmacology and Toxicology. 2008  |   Pubmed ID: 17883368
• The Neurotransmitter Cycle and Quantal Size
  Neuron. Sep, 2007  |   Pubmed ID: 17880890
• Physiology Versus Pathology in Parkinson's Disease
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007  |   Pubmed ID: 17623781
• Vesicular Glutamate Transporter 1 is Required for Photoreceptor Synaptic Signaling but Not for Intrinsic Visual Functions
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2007  |   Pubmed ID: 17611277
• Thyronamines Inhibit Plasma Membrane and Vesicular Monoamine Transport
  ACS Chemical Biology. Jun, 2007  |   Pubmed ID: 17530732
• Do Different Endocytic Pathways Make Different Synaptic Vesicles?
  Current Opinion in Neurobiology. Jun, 2007  |   Pubmed ID: 17449236
• Alpha-synuclein Overexpression in PC12 and Chromaffin Cells Impairs Catecholamine Release by Interfering with a Late Step in Exocytosis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2006  |   Pubmed ID: 17108165
• Secretion of L-glutamate from Osteoclasts Through Transcytosis
  The EMBO Journal. Sep, 2006  |   Pubmed ID: 16957773
• Alpha-synuclein Overexpression Increases Cytosolic Catecholamine Concentration
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2006  |   Pubmed ID: 16957086
• Synaptic Vesicles: Half Full or Half Empty?
  Neuron. Sep, 2006  |   Pubmed ID: 16950150
• Distinct Endocytic Pathways Control the Rate and Extent of Synaptic Vesicle Protein Recycling
  Neuron. Jul, 2006  |   Pubmed ID: 16815333
• Distribution of Vesicular Glutamate Transporters 1 and 2 in the Rat Spinal Cord, with a Note on the Spinocervical Tract
  The Journal of Comparative Neurology. Aug, 2006  |   Pubmed ID: 16786558
• Vesicular Glutamate Transporter 3 (VGLUT3) Identifies Spatially Segregated Excitatory Terminals in the Rat Substantia Nigra
  The European Journal of Neuroscience. Feb, 2006  |   Pubmed ID: 16519671
• PharmGKB Submission Update: VI. PMT Submissions of Genetic Variations in Neurotransmitter Transporters (SLC6, SLC17, and SLC18) to the PharmGKB Network
  Pharmacological Reviews. Mar, 2006  |   Pubmed ID: 16507879
• Structural Variants in the Vesicular Monoamine Transporter Do Not Contribute to Sporadic Parkinson's Disease
  Movement Disorders : Official Journal of the Movement Disorder Society. Mar, 2006  |   Pubmed ID: 16450345
• Changes in Purinergic Signaling After Cerebral Injury -- Involvement of Glutamatergic Mechanisms?
  International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience. Apr-May, 2006  |   Pubmed ID: 16387466
• Functional Implications of Neurotransmitter Co-release: Glutamate and GABA Share the Load
  Current Opinion in Pharmacology. Feb, 2006  |   Pubmed ID: 16359920
• Neural Activity Controls the Synaptic Accumulation of Alpha-synuclein
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2005  |   Pubmed ID: 16306404
• Sorting of Vesicular Monoamine Transporter 2 to the Regulated Secretory Pathway Confers the Somatodendritic Exocytosis of Monoamines
  Neuron. Nov, 2005  |   Pubmed ID: 16301178
• A Combinatorial Code for the Interaction of Alpha-synuclein with Membranes
  The Journal of Biological Chemistry. Sep, 2005  |   Pubmed ID: 16020543
• Antidepressants and the Monoamine Masquerade
  Neuron. Apr, 2005  |   Pubmed ID: 15820686
• Normal Biogenesis and Cycling of Empty Synaptic Vesicles in Dopamine Neurons of Vesicular Monoamine Transporter 2 Knockout Mice
  Molecular Biology of the Cell. Jan, 2005  |   Pubmed ID: 15496457
• Expression of the Vesicular Glutamate Transporters During Development Indicates the Widespread Corelease of Multiple Neurotransmitters
  The Journal of Comparative Neurology. Dec, 2004  |   Pubmed ID: 15515175
• The Effect of Rare Human Sequence Variants on the Function of Vesicular Monoamine Transporter 2
  Pharmacogenetics. Sep, 2004  |   Pubmed ID: 15475732
• Evidence That Certain Retinal Bipolar Cells Use Both Glutamate and GABA
  The Journal of Comparative Neurology. Oct, 2004  |   Pubmed ID: 15368537
• Vesicular Glutamate Transporter 3 Expression Identifies Glutamatergic Amacrine Cells in the Rodent Retina
  The Journal of Comparative Neurology. Sep, 2004  |   Pubmed ID: 15329888
• Lipid Rafts Mediate the Synaptic Localization of Alpha-synuclein
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004  |   Pubmed ID: 15282274
• Endocannabinoid-independent Retrograde Signaling at Inhibitory Synapses in Layer 2/3 of Neocortex: Involvement of Vesicular Glutamate Transporter 3
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2004  |   Pubmed ID: 15163690
• Vesicular Glutamate Transporters 1 and 2 Target to Functionally Distinct Synaptic Release Sites
  Science (New York, N.Y.). Jun, 2004  |   Pubmed ID: 15118123
• VGLUTs Define Subsets of Excitatory Neurons and Suggest Novel Roles for Glutamate
  Trends in Neurosciences. Feb, 2004  |   Pubmed ID: 15102489
• Electrochemical Monitoring of Transport by a Vesicular Monoamine Transporter Expressed in Xenopus Oocytes
  Journal of Neuroscience Methods. Feb, 2004  |   Pubmed ID: 14757360
• Organic Anion Transport is the Primary Function of the SLC17/type I Phosphate Transporter Family
  Pflügers Archiv : European Journal of Physiology. Feb, 2004  |   Pubmed ID: 12811560
• Complementary Distribution of Type 1 Cannabinoid Receptors and Vesicular Glutamate Transporter 3 in Basal Forebrain Suggests Input-specific Retrograde Signalling by Cholinergic Neurons
  The European Journal of Neuroscience. Oct, 2003  |   Pubmed ID: 14622230
• Expression of Plasma Membrane GABA Transporters but Not of the Vesicular GABA Transporter in Dentate Granule Cells After Kainic Acid Seizures
  Hippocampus. 2003  |   Pubmed ID: 14620876
• Plasma Membrane and Vesicular Glutamate Transporter MRNAs/proteins in Hypothalamic Neurons That Regulate Body Weight
  The European Journal of Neuroscience. Sep, 2003  |   Pubmed ID: 12956725
• Complementary Distribution of Vesicular Glutamate Transporters 1 and 2 in the Nucleus Accumbens of Rat: Relationship to Calretinin-containing Extrinsic Innervation and Calbindin-immunoreactive Neurons
  The Journal of Comparative Neurology. Oct, 2003  |   Pubmed ID: 12926012
• Cellular Localization of Three Vesicular Glutamate Transporter MRNAs and Proteins in Rat Spinal Cord and Dorsal Root Ganglia
  Synapse (New York, N.Y.). Nov, 2003  |   Pubmed ID: 12923814
• The H+-coupled Electrogenic Lysosomal Amino Acid Transporter LYAAT1 Localizes to the Axon and Plasma Membrane of Hippocampal Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2003  |   Pubmed ID: 12598615
• Postnatal Development of the Glutamate Vesicular Transporter VGLUT1 in Rat Cerebral Cortex
  Brain Research. Developmental Brain Research. Feb, 2003  |   Pubmed ID: 12586437
• Vesicular Neurotransmitter Transporter Expression in Developing Postnatal Rodent Retina: GABA and Glycine Precede Glutamate
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2003  |   Pubmed ID: 12533612
• The Identification of Vesicular Glutamate Transporter 3 Suggests Novel Modes of Signaling by Glutamate
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002  |   Pubmed ID: 12388773
• Methamphetamine-induced Degeneration of Dopaminergic Neurons Involves Autophagy and Upregulation of Dopamine Synthesis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2002  |   Pubmed ID: 12388602
• Cell-specific Expression of the Glutamine Transporter SN1 Suggests Differences in Dependence on the Glutamine Cycle
  The European Journal of Neuroscience. May, 2002  |   Pubmed ID: 12059969
• The Glutamine Commute: Take the N Line and Transfer to the A
  The Journal of Cell Biology. Apr, 2002  |   Pubmed ID: 11980913
• Regulation of the Glutamine Transporter SN1 by Extracellular PH and Intracellular Sodium Ions
  The Journal of Physiology. Feb, 2002  |   Pubmed ID: 11850497
• Glutamine Uptake by Neurons: Interaction of Protons with System a Transporters
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002  |   Pubmed ID: 11756489