Robert Damoiseaux University of California Los Angeles Biography Publications Institution JoVE Articles Robert Damoiseaux has not added a biography. If you are Robert Damoiseaux and would like to personalize this page please email our Author Liaison for assistance. Publications Reprogramming of Nucleotide Metabolism by Interferon Confers Dependence on the Replication Stress Response Pathway in Pancreatic Cancer Cells Cell Reports. 01, 2022 | Pubmed ID: 35021095 Antiviral Drug Screen Identifies DNA-damage Response Inhibitor As Potent Blocker of SARS-CoV-2 Replication Cell Reports. 04, 2021 | Pubmed ID: 33784499 PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 04, 2021 | Pubmed ID: 33441295 Commercial Immunoglobulin Products Contain Cross-reactive but Not Neutralizing Antibodies Against SARS-CoV-2 The Journal of Allergy and Clinical Immunology. 03, 2021 | Pubmed ID: 33358557 Uncoupling Interferon Signaling and Antigen Presentation to Overcome Immunotherapy Resistance Due to JAK1 Loss in Melanoma Science Translational Medicine. 10, 2020 | Pubmed ID: 33055240 High-throughput Screening Identifies Modulators of Sarcospan That Stabilize Muscle Cells and Exhibit Activity in the Mouse Model of Duchenne Muscular Dystrophy Skeletal Muscle. 09, 2020 | Pubmed ID: 32948250 Repurposing Metformin, Simvastatin and Digoxin As a Combination for Targeted Therapy for Pancreatic Ductal Adenocarcinoma Cancer Letters. 10, 2020 | Pubmed ID: 32829010 Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors Within Nucleotide Metabolism Cell Chemical Biology. 02, 2020 | Pubmed ID: 31734178 Development of a High-throughput Screen to Identify Small Molecule Enhancers of Sarcospan for the Treatment of Duchenne Muscular Dystrophy Skeletal Muscle. 12, 2019 | Pubmed ID: 31831063 A Scalable Filtration Method for High Throughput Screening Based on Cell Deformability Lab on a Chip. 01, 2019 | Pubmed ID: 30566156 Reporter Gene Assays Using Viral Functional Genomics Libraries Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29671267 Reporter Gene Assays Using Transfectable Functional Genomics Libraries Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29671266 Making It All Work: Functional Genomics and Reporter Gene Assays Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29671265 High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29671264 Gα Facilitates Shortening in Human Airway Smooth Muscle by Modulating Phosphoinositide 3-kinase-mediated Activation in a RhoA-dependent Manner British Journal of Pharmacology. Dec, 2017 | Pubmed ID: 28921504 Direct Quantification of Gamma H2AX by Cell-based High Throughput Screening for Evaluation of Genotoxicity of Pesticides in a Human Thyroid Cell Lines Environmental and Molecular Mutagenesis. 08, 2017 | Pubmed ID: 28640454 Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44 The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28167535 Glucocorticoids Suppress Renal Cell Carcinoma Progression by Enhancing Na,K-ATPase Beta-1 Subunit Expression PloS One. 2015 | Pubmed ID: 25836370 Identification of Small Molecules That Disrupt Signaling Between ABL and Its Positive Regulator RIN1 PloS One. 2015 | Pubmed ID: 25811598 Cytolethal Distending Toxins Require Components of the ER-associated Degradation Pathway for Host Cell Entry PLoS Pathogens. Jul, 2014 | Pubmed ID: 25078082 UCLA's Molecular Screening Shared Resource: Enhancing Small Molecule Discovery with Functional Genomics and New Technology Combinatorial Chemistry & High Throughput Screening. May, 2014 | Pubmed ID: 24661210 Calcium Signaling Via Orai1 is Essential for Induction of the Nuclear Orphan Receptor Pathway to Drive Th17 Differentiation Journal of Immunology (Baltimore, Md. : 1950). Jan, 2014 | Pubmed ID: 24307733 Selective Inhibitor of Endosomal Trafficking Pathways Exploited by Multiple Toxins and Viruses Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24191014 Genome-wide RNAi High-throughput Screen Identifies Proteins Necessary for the AHR-dependent Induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2013 | Pubmed ID: 23997114 Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography Journal of Medicinal Chemistry. Sep, 2013 | Pubmed ID: 23947754 A New Series of Small Molecular Weight Compounds Induce Read Through of All Three Types of Nonsense Mutations in the ATM Gene Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2013 | Pubmed ID: 23774824 A Broadly Applicable High-throughput Screening Strategy Identifies New Regulators of Dlg4 (Psd-95) Alternative Splicing Genome Research. Jun, 2013 | Pubmed ID: 23636947 A Small Molecule Inhibitor of Redox-regulated Protein Translocation into Mitochondria Developmental Cell. Apr, 2013 | Pubmed ID: 23597483 High-throughput Screening of Small Molecules Identifies Hepcidin Antagonists Molecular Pharmacology. Mar, 2013 | Pubmed ID: 23292796 Zebrafish High-throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1 Small (Weinheim an Der Bergstrasse, Germany). May, 2013 | Pubmed ID: 23180726 Size Influences the Cytotoxicity of Poly (lactic-co-glycolic Acid) (PLGA) and Titanium Dioxide (TiO(2)) Nanoparticles Archives of Toxicology. Jun, 2013 | Pubmed ID: 22983807 Size of TiO(2) Nanoparticles Influences Their Phototoxicity: an in Vitro Investigation Archives of Toxicology. Jan, 2013 | Pubmed ID: 22885792 Dantrolene Enhances Antisense-mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy Science Translational Medicine. Dec, 2012 | Pubmed ID: 23241744 Genome-wide Assessment in Escherichia Coli Reveals Time-dependent Nanotoxicity Paradigms ACS Nano. Nov, 2012 | Pubmed ID: 23039911 Inhibition of Aminoacylase 3 Protects Rat Brain Cortex Neuronal Cells from the Toxicity of 4-hydroxy-2-nonenal Mercapturate and 4-hydroxy-2-nonenal Toxicology and Applied Pharmacology. Sep, 2012 | Pubmed ID: 22819785 Fluoxetine is a Potent Inhibitor of Coxsackievirus Replication Antimicrobial Agents and Chemotherapy. Sep, 2012 | Pubmed ID: 22751539 Quantitative Detection of PfHRP2 in Saliva of Malaria Patients in the Philippines Malaria Journal. 2012 | Pubmed ID: 22631858 Automated Phenotype Recognition for Zebrafish Embryo Based in Vivo High Throughput Toxicity Screening of Engineered Nano-materials PloS One. 2012 | Pubmed ID: 22506062 Use of Metal Oxide Nanoparticle Band Gap to Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation ACS Nano. May, 2012 | Pubmed ID: 22502734 Combination of Rad001 (everolimus) and Propachlor Synergistically Induces Apoptosis Through Enhanced Autophagy in Prostate Cancer Cells Molecular Cancer Therapeutics. Jun, 2012 | Pubmed ID: 22491797 Genome-wide Bacterial Toxicity Screening Uncovers the Mechanisms of Toxicity of a Cationic Polystyrene Nanomaterial Environmental Science & Technology. Feb, 2012 | Pubmed ID: 22148163 Synergistic Bactericidal Activity of Ag-TiO₂ Nanoparticles in Both Light and Dark Conditions Environmental Science & Technology. Oct, 2011 | Pubmed ID: 21866941 A Molecular Screening Approach to Identify and Characterize Inhibitors of Glioblastoma Stem Cells Molecular Cancer Therapeutics. Oct, 2011 | Pubmed ID: 21859839 High Content Screening in Zebrafish Speeds Up Hazard Ranking of Transition Metal Oxide Nanoparticles ACS Nano. Sep, 2011 | Pubmed ID: 21851096 Seeing the Light: Luminescent Reporter Gene Assays Combinatorial Chemistry & High Throughput Screening. Sep, 2011 | Pubmed ID: 21564017 High Throughput Screening of Small Molecule Libraries for Modifiers of Radiation Responses International Journal of Radiation Biology. Aug, 2011 | Pubmed ID: 21401317 Differential Expression of Syndecan-1 Mediates Cationic Nanoparticle Toxicity in Undifferentiated Versus Differentiated Normal Human Bronchial Epithelial Cells ACS Nano. Apr, 2011 | Pubmed ID: 21366263 Use of a High-throughput Screening Approach Coupled with in Vivo Zebrafish Embryo Screening to Develop Hazard Ranking for Engineered Nanomaterials ACS Nano. Mar, 2011 | Pubmed ID: 21323332 No Time to Lose--high Throughput Screening to Assess Nanomaterial Safety Nanoscale. Apr, 2011 | Pubmed ID: 21301704 Self-organizing Map Analysis of Toxicity-related Cell Signaling Pathways for Metal and Metal Oxide Nanoparticles Environmental Science & Technology. Feb, 2011 | Pubmed ID: 21250674 Metabolic Imaging Allows Early Prediction of Response to Vandetanib Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2011 | Pubmed ID: 21233183 Stability, Bioavailability, and Bacterial Toxicity of ZnO and Iron-doped ZnO Nanoparticles in Aquatic Media Environmental Science & Technology. Jan, 2011 | Pubmed ID: 21133426 Microfluidic Image Cytometry Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21104065 High-throughput Screening of Silver Nanoparticle Stability and Bacterial Inactivation in Aquatic Media: Influence of Specific Ions Environmental Science & Technology. Oct, 2010 | Pubmed ID: 20873875 High-content Screening for Biofilm Assays Journal of Biomolecular Screening. Aug, 2010 | Pubmed ID: 20639506 Chemical Genetics Screen for Enhancers of Rapamycin Identifies a Specific Inhibitor of an SCF Family E3 Ubiquitin Ligase Nature Biotechnology. Jul, 2010 | Pubmed ID: 20581845 Substrate Specificity of the TIM22 Mitochondrial Import Pathway Revealed with Small Molecule Inhibitor of Protein Translocation Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20457929 A Broad-spectrum Antiviral Targeting Entry of Enveloped Viruses Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133606 Integrated Pathways for Neutrophil Recruitment and Inflammation in Leprosy The Journal of Infectious Diseases. Feb, 2010 | Pubmed ID: 20070238 Use of a Rapid Cytotoxicity Screening Approach to Engineer a Safer Zinc Oxide Nanoparticle Through Iron Doping ACS Nano. Jan, 2010 | Pubmed ID: 20043640 Rottlerin Stimulates Apoptosis in Pancreatic Cancer Cells Through Interactions with Proteins of the Bcl-2 Family American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2010 | Pubmed ID: 19762431 High-throughput Screening Identifies Two Classes of Antibiotics As Radioprotectors: Tetracyclines and Fluoroquinolones Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2009 | Pubmed ID: 19920105 Discovery and Structure-activity Relationship Analysis of Staphylococcus Aureus Sortase A Inhibitors Bioorganic & Medicinal Chemistry. Oct, 2009 | Pubmed ID: 19781950 Nonaminoglycoside Compounds Induce Readthrough of Nonsense Mutations The Journal of Experimental Medicine. Sep, 2009 | Pubmed ID: 19770270 Integrated Chemical Genomics Reveals Modifiers of Survival in Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2009 | Pubmed ID: 19074420 Ion Channel and Toxin Measurement Using a High Throughput Lipid Membrane Platform Biosensors & Bioelectronics. Feb, 2009 | Pubmed ID: 18849158 A High-throughput Screening Strategy Identifies Cardiotonic Steroids As Alternative Splicing Modulators Proceedings of the National Academy of Sciences of the United States of America. Aug, 2008 | Pubmed ID: 18678901 Regulation of Kaposi's Sarcoma-associated Herpesvirus Reactivation by Dopamine Receptor-mediated Signaling Pathways Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2008 | Pubmed ID: 18645521 The Small Molecule Harmine is an Antidiabetic Cell-type-specific Regulator of PPARgamma Expression Cell Metabolism. May, 2007 | Pubmed ID: 17488638 Amiodarone and Bepridil Inhibit Anthrax Toxin Entry into Host Cells Antimicrobial Agents and Chemotherapy. Jul, 2007 | Pubmed ID: 17485504 Mycophenolic Acid is a Potent Inhibitor of Angiogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2006 | Pubmed ID: 16990565 Cell-based Chemical Genetic Screen Identifies Damnacanthal As an Inhibitor of HIV-1 Vpr Induced Cell Death Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16904642 PNA-encoded Protease Substrate Microarrays Chemistry & Biology. Oct, 2004 | Pubmed ID: 15489162 SRC Family Kinases: Potential Targets for the Treatment of Human Cancer and Leukemia Current Pharmaceutical Design. 2003 | Pubmed ID: 14529415 Towards the Generation of Artificial O6-alkylguanine-DNA Alkyltransferases: in Vitro Selection of Antibodies with Reactive Cysteine Residues Chembiochem : a European Journal of Chemical Biology. Jun, 2002 | Pubmed ID: 12325014 Гидрогелевые матрицы обеспечивают повышенную пропускную способность для скрининговых эффектов компонентов матрицы и терапии в 3D-моделях опухолей Jesse Liang1, Alireza Sohrabi1, Mary Epperson1, Laila M. Rad1, Kelly Tamura1, Mayilone Sathialingam1, Thamira Skandakumar1, Philip Lue1, Jeremy Huang1, James Popoli1, Aidan Yackly1, Michael Bick1, Ze Zhong Wang1, Chia-Chun Chen1, Grigor Varuzhanyan1, Robert Damoiseaux1, Stephanie K. Seidlits1 1University of California Los Angeles JoVE 63791 Bioengineering Упрощенный высокопроизводительный анализ сократимости одноклеточных клеток с использованием микроструктурированных эластомеров Lara Hairapetian1, Enrico Cortes1, Junyi Zhao1, Yao Wang1, Ricky Huang1, Robert Damoiseaux1,2, Ivan Pushkarsky1 1Forcyte Biotechnologies, 2University of California, Los Angeles JoVE 63211 Bioengineering Комплексная оценка зародышевой линии химической токсичности Использование нематоды Daniela A. Parodi1, Robert Damoiseaux3, Patrick Allard1,2 1Institute for Society and Genetics, University of California, Los Angeles, 2Environmental Health Sciences, University of California, Los Angeles, 3California Nanosystems Institute, Department of Molecular and Medical Pharmacology, University of California, Los Angeles Developmental Biology
Гидрогелевые матрицы обеспечивают повышенную пропускную способность для скрининговых эффектов компонентов матрицы и терапии в 3D-моделях опухолей Jesse Liang1, Alireza Sohrabi1, Mary Epperson1, Laila M. Rad1, Kelly Tamura1, Mayilone Sathialingam1, Thamira Skandakumar1, Philip Lue1, Jeremy Huang1, James Popoli1, Aidan Yackly1, Michael Bick1, Ze Zhong Wang1, Chia-Chun Chen1, Grigor Varuzhanyan1, Robert Damoiseaux1, Stephanie K. Seidlits1 1University of California Los Angeles JoVE 63791 Bioengineering
Упрощенный высокопроизводительный анализ сократимости одноклеточных клеток с использованием микроструктурированных эластомеров Lara Hairapetian1, Enrico Cortes1, Junyi Zhao1, Yao Wang1, Ricky Huang1, Robert Damoiseaux1,2, Ivan Pushkarsky1 1Forcyte Biotechnologies, 2University of California, Los Angeles JoVE 63211 Bioengineering
Комплексная оценка зародышевой линии химической токсичности Использование нематоды Daniela A. Parodi1, Robert Damoiseaux3, Patrick Allard1,2 1Institute for Society and Genetics, University of California, Los Angeles, 2Environmental Health Sciences, University of California, Los Angeles, 3California Nanosystems Institute, Department of Molecular and Medical Pharmacology, University of California, Los Angeles Developmental Biology
