Robert Huber Biography Publications JoVE Articles Robert Huber has not added a biography. If you are Robert Huber and would like to personalize this page please email our Author Liaison for assistance. Publications Chemical Biology Approaches Reveal Conserved Features of a C-terminal Processing PDZ Protease Chembiochem : a European Journal of Chemical Biology. Feb, 2012 | Pubmed ID: 22267294 The Cyclin-dependent Kinase Inhibitor Roscovitine Inhibits Kinase Activity, Cell Proliferation, Multicellular Development, and Cdk5 Nuclear Translocation in Dictyostelium Discoideum Journal of Cellular Biochemistry. Mar, 2012 | Pubmed ID: 22234985 EGF-like Peptide of Dictyostelium Discoideum is Not a Chemoattractant but It Does Restore Folate-mediated Chemotaxis in the Presence of Signal Transduction Inhibitors Peptides. Jan, 2012 | Pubmed ID: 22234048 Alteration of C-Fos MRNA in the Accessory Lobe of Crayfish is Associated with a Conditioned-cocaine Induced Reward Neuroscience Research. Mar, 2012 | Pubmed ID: 22178542 Repeated Cocaine Treatments Induce Distinct Locomotor Effects in Crayfish Brain Research Bulletin. Feb, 2012 | Pubmed ID: 22173062 Structure of the Stapled P53 Peptide Bound to Mdm2 Journal of the American Chemical Society. Jan, 2012 | Pubmed ID: 22148351 Hydroxyureas As Noncovalent Proteasome Inhibitors Angewandte Chemie (International Ed. in English). Jan, 2012 | Pubmed ID: 22105886 Predictive Tool for Recombinant Protein Production in Escherichia Coli Shake-Flask Cultures Using an On-line Monitoring System Biotechnology Progress. Jan, 2012 | Pubmed ID: 22012896 Molecular Architecture of the Spire-actin Nucleus and Its Implication for Actin Filament Assembly Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22106272 Aggression Advances in Genetics. 2011 | Pubmed ID: 22078474 Extended Coherence Length Fourier Domain Mode Locked Lasers at 1310 Nm Optics Express. Oct, 2011 | Pubmed ID: 21997102 Wavelength Swept Amplified Spontaneous Emission Source for High Speed Retinal Optical Coherence Tomography at 1060 Nm Journal of Biophotonics. Aug, 2011 | Pubmed ID: 21780301 Nucleocytoplasmic Transfer of Cyclin Dependent Kinase 5 and Its Binding to Puromycin-sensitive Aminopeptidase in Dictyostelium Discoideum Histochemistry and Cell Biology. Aug, 2011 | Pubmed ID: 21766205 Extended Focus High-speed Swept Source OCT with Self-reconstructive Illumination Optics Express. Jun, 2011 | Pubmed ID: 21716451 Instantaneous Lineshape Analysis of Fourier Domain Mode-locked Lasers Optics Express. Apr, 2011 | Pubmed ID: 21643132 Protein Quality Control in the Bacterial Periplasm Annual Review of Microbiology. 2011 | Pubmed ID: 21639788 D-amphetamine Stimulates Unconditioned Exploration/approach Behaviors in Crayfish: Towards a Conserved Evolutionary Function of Ancestral Drug Reward Pharmacology, Biochemistry, and Behavior. Jul, 2011 | Pubmed ID: 21504757 Utilizing High-throughput Experimentation to Enhance Specific Productivity of an E.coli T7 Expression System by Phosphate Limitation BMC Biotechnology. 2011 | Pubmed ID: 21414195 An Extracellular Matrix, Calmodulin-binding Protein from Dictyostelium with EGF-like Repeats That Enhance Cell Motility Cellular Signalling. Jul, 2011 | Pubmed ID: 21402150 Megahertz OCT for Ultrawide-field Retinal Imaging with a 1050 Nm Fourier Domain Mode-locked Laser Optics Express. Feb, 2011 | Pubmed ID: 21369128 HTRA Proteases: Regulated Proteolysis in Protein Quality Control Nature Reviews. Molecular Cell Biology. Mar, 2011 | Pubmed ID: 21326199 Screening for Enzyme Activity in Turbid Suspensions with Scattered Light Biotechnology Progress. Mar-Apr, 2011 | Pubmed ID: 21302369 High-spatial-resolution Sub-surface Imaging Using a Laser-based Acoustic Microscopy Technique IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Jan, 2011 | Pubmed ID: 21244990 EGF-like Peptide-enhanced Cell Motility in Dictyostelium Functions Independently of the CAMP-mediated Pathway and Requires Active Ca2+/calmodulin Signaling Cellular Signalling. Apr, 2011 | Pubmed ID: 21195758 Drug-sensitive Reward in Crayfish: an Invertebrate Model System for the Study of SEEKING, Reward, Addiction, and Withdrawal Neuroscience and Biobehavioral Reviews. Oct, 2011 | Pubmed ID: 21182861 Elucidation of the α-keto-aldehyde Binding Mechanism: a Lead Structure Motif for Proteasome Inhibition Angewandte Chemie (International Ed. in English). Jan, 2011 | Pubmed ID: 21154547 Predissociation Via Conformational Change: Photodissociation of N,N-dimethylnitrosamine in the S(1) State The Journal of Physical Chemistry. A. Dec, 2010 | Pubmed ID: 21090731 Direct Measurement of the Instantaneous Linewidth of Rapidly Wavelength-swept Lasers Optics Letters. Nov, 2010 | Pubmed ID: 21081979 Wavelength Swept Amplified Spontaneous Emission Source for High Speed Retinal Optical Coherence Tomography at 1060 Nm Journal of Biophotonics. Nov, 2010 | Pubmed ID: 21077134 One- and Two-photon Spectroscopy of Highly Excited States of Alkali-metal Atoms on Helium Nanodroplets The Journal of Chemical Physics. Oct, 2010 | Pubmed ID: 21033800 Fourier Domain Mode-locked Swept Source at 1050 Nm Based on a Tapered Amplifier Optics Express. Jul, 2010 | Pubmed ID: 20720964 20S Proteasome Inhibition: Designing Noncovalent Linear Peptide Mimics of the Natural Product TMC-95A ChemMedChem. Oct, 2010 | Pubmed ID: 20715286 Multi-megahertz OCT: High Quality 3D Imaging at 20 Million A-scans and 4.5 GVoxels Per Second Optics Express. Jul, 2010 | Pubmed ID: 20639955 Flavin Mononucleotide-based Fluorescent Reporter Proteins Outperform Green Fluorescent Protein-like Proteins As Quantitative in Vivo Real-time Reporters Applied and Environmental Microbiology. Sep, 2010 | Pubmed ID: 20601504 The Multicopper Oxidase from the Archaeon Pyrobaculum Aerophilum Shows Nitrous Oxide Reductase Activity The FEBS Journal. Aug, 2010 | Pubmed ID: 20597980 Determinants of Structural and Functional Plasticity of a Widely Conserved Protease Chaperone Complex Nature Structural & Molecular Biology. Jul, 2010 | Pubmed ID: 20581826 HtrA Proteases Have a Conserved Activation Mechanism That Can Be Triggered by Distinct Molecular Cues Nature Structural & Molecular Biology. Jul, 2010 | Pubmed ID: 20581825 Structures of Actin-bound Wiskott-Aldrich Syndrome Protein Homology 2 (WH2) Domains of Spire and the Implication for Filament Nucleation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20538977 Replication Methods and Tools in High-throughput Cultivation Processes - Recognizing Potential Variations of Growth and Product Formation by On-line Monitoring BMC Biotechnology. 2010 | Pubmed ID: 20233443 Conversion of a Regulatory into a Degradative Protease Journal of Molecular Biology. Apr, 2010 | Pubmed ID: 20184896 Transdisciplinary EU Science Institute Needs Funds Urgently Nature. Feb, 2010 | Pubmed ID: 20164899 Increased Product Formation Induced by a Directed Secondary Substrate Limitation in a Batch Hansenula Polymorpha Culture Applied Microbiology and Biotechnology. Mar, 2010 | Pubmed ID: 19859706 Effects of a Single and Repeated Morphine Treatment on Conditioned and Unconditioned Behavioral Sensitization in Crayfish Behavioural Brain Research. Mar, 2010 | Pubmed ID: 19836421 Wavelength Swept Amplified Spontaneous Emission Source Optics Express. Oct, 2009 | Pubmed ID: 20372613 Ultra-rapid Dispersion Measurement in Optical Fibers Optics Express. Dec, 2009 | Pubmed ID: 20052213 A Theoretical Description of Fourier Domain Mode Locked Lasers Optics Express. Dec, 2009 | Pubmed ID: 20052113 Structural Basis for Ca2+-independence and Activation by Homodimerization of Tomato Subtilase 3 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009 | Pubmed ID: 19805099 Nonlinear Optical Frequency Conversion of an Amplified Fourier Domain Mode Locked (FDML) Laser Optics Express. Sep, 2009 | Pubmed ID: 19770897 Syringolin A Selectively Labels the 20 S Proteasome in Murine EL4 and Wild-type and Bortezomib-adapted Leukaemic Cell Lines Chembiochem : a European Journal of Chemical Biology. Nov, 2009 | Pubmed ID: 19746508 Structure, Function and Regulation of the Conserved Serine Proteases DegP and DegS of Escherichia Coli Research in Microbiology. Nov, 2009 | Pubmed ID: 19695325 Ultra High-speed Swept Source OCT Imaging of the Anterior Segment of Human Eye at 200 KHz with Adjustable Imaging Range Optics Express. Aug, 2009 | Pubmed ID: 19687967 Structural Basis of Substrate Specificity of Plant 12-oxophytodienoate Reductases Journal of Molecular Biology. Oct, 2009 | Pubmed ID: 19660473 Robo-Lector - a Novel Platform for Automated High-throughput Cultivations in Microtiter Plates with High Information Content Microbial Cell Factories. 2009 | Pubmed ID: 19646274 Structural and Functional Studies of the Yeast Class II Hda1 Histone Deacetylase Complex Journal of Molecular Biology. Aug, 2009 | Pubmed ID: 19573535 Recent Developments in Fourier Domain Mode Locked Lasers for Optical Coherence Tomography: Imaging at 1310 Nm Vs. 1550 Nm Wavelength Journal of Biophotonics. Jul, 2009 | Pubmed ID: 19565537 Dispersion, Coherence and Noise of Fourier Domain Mode Locked Lasers Optics Express. Jun, 2009 | Pubmed ID: 19506645 Design of Anti- and Pro-aggregation Variants to Assess the Effects of Methionine Oxidation in Human Prion Protein Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19416900 Equalizing Growth in High-throughput Small Scale Cultivations Via Precultures Operated in Fed-batch Mode Biotechnology and Bioengineering. Aug, 2009 | Pubmed ID: 19415772 Synthetic and Structural Studies on Syringolin A and B Reveal Critical Determinants of Selectivity and Potency of Proteasome Inhibition Proceedings of the National Academy of Sciences of the United States of America. Apr, 2009 | Pubmed ID: 19359491 Subharmonic Fourier Domain Mode Locking Optics Letters. Mar, 2009 | Pubmed ID: 19282912 Mammalian Metallopeptidase Inhibition at the Defense Barrier of Ascaris Parasite Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19179285 An EGF-like Peptide Sequence from Dictyostelium Enhances Cell Motility and Chemotaxis Biochemical and Biophysical Research Communications. Feb, 2009 | Pubmed ID: 19121290 The Persisting Challenge of Selective and Specific Proteasome Inhibition Journal of Peptide Science : an Official Publication of the European Peptide Society. Feb, 2009 | Pubmed ID: 19109822 Drug-seeking Behavior in an Invertebrate System: Evidence of Morphine-induced Reward, Extinction and Reinstatement in Crayfish Behavioural Brain Research. Feb, 2009 | Pubmed ID: 18822319 Raman-pumped Fourier-domain Mode-locked Laser: Analysis of Operation and Application for Optical Coherence Tomography Optics Letters. Dec, 2008 | Pubmed ID: 19037436 Real Time En Face Fourier-domain Optical Coherence Tomography with Direct Hardware Frequency Demodulation Optics Letters. Nov, 2008 | Pubmed ID: 18978919 Ultrahigh-speed Optical Coherence Tomography for Three-dimensional and En Face Imaging of the Retina and Optic Nerve Head Investigative Ophthalmology & Visual Science. Nov, 2008 | Pubmed ID: 18658089 Demyelinating Myelin Oligodendrocyte Glycoprotein-specific Autoantibody Response is Focused on One Dominant Conformational Epitope Region in Rodents Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18606679 Structure of Lumazine Protein, an Optical Transponder of Luminescent Bacteria Journal of Molecular Biology. Sep, 2008 | Pubmed ID: 18602927 K-space Linear Fourier Domain Mode Locked Laser and Applications for Optical Coherence Tomography Optics Express. Jun, 2008 | Pubmed ID: 18545605 Photothermal Detection of Gold Nanoparticles Using Phase-sensitive Optical Coherence Tomography Optics Express. Mar, 2008 | Pubmed ID: 18542535 Improved Spectral Optical Coherence Tomography Using Optical Frequency Comb Optics Express. Mar, 2008 | Pubmed ID: 18542513 Interplay of PDZ and Protease Domain of DegP Ensures Efficient Elimination of Misfolded Proteins Proceedings of the National Academy of Sciences of the United States of America. Jun, 2008 | Pubmed ID: 18505836 A Plant Pathogen Virulence Factor Inhibits the Eukaryotic Proteasome by a Novel Mechanism Nature. Apr, 2008 | Pubmed ID: 18401409 X-ray Structures of Sap1 and Sap5: Structural Comparison of the Secreted Aspartic Proteinases from Candida Albicans Proteins. Sep, 2008 | Pubmed ID: 18384081 A New Lineage of Halophilic, Wall-less, Contractile Bacteria from a Brine-filled Deep of the Red Sea Journal of Bacteriology. May, 2008 | Pubmed ID: 18326567 Di-myo-inositol Phosphate and Novel UDP-sugars Accumulate in the Extreme Hyperthermophile Pyrolobus Fumarii Extremophiles : Life Under Extreme Conditions. May, 2008 | Pubmed ID: 18286223 High-resolution Optical Coherence Tomography Imaging of the Living Kidney Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2008 | Pubmed ID: 18268476 Halorhabdus Tiamatea Sp. Nov., a Non-pigmented, Extremely Halophilic Archaeon from a Deep-sea, Hypersaline Anoxic Basin of the Red Sea, and Emended Description of the Genus Halorhabdus International Journal of Systematic and Evolutionary Microbiology. Jan, 2008 | Pubmed ID: 18175711 Comparison of Three-dimensional Optical Coherence Tomography and High Resolution Photography for Art Conservation Studies Optics Express. Nov, 2007 | Pubmed ID: 19550884 High Speed Engine Gas Thermometry by Fourier-domain Mode-locked Laser Absorption Spectroscopy Optics Express. Nov, 2007 | Pubmed ID: 19550795 Swept Source Optical Coherence Microscopy Using a Fourier Domain Mode-locked Laser Optics Express. May, 2007 | Pubmed ID: 19546926 Chymotryptic Specificity Determinants in the 1.0 A Structure of the Zinc-inhibited Human Tissue Kallikrein 7 Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17909180 Behavioral Functions of the Mesolimbic Dopaminergic System: an Affective Neuroethological Perspective Brain Research Reviews. Dec, 2007 | Pubmed ID: 17905440 Structural Basis of the Zinc Inhibition of Human Tissue Kallikrein 5 Journal of Molecular Biology. Nov, 2007 | Pubmed ID: 17881000 Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin Biochemistry. Sep, 2007 | Pubmed ID: 17685636 Crystal Structures of MMP-9 Complexes with Five Inhibitors: Contribution of the Flexible Arg424 Side-chain to Selectivity Journal of Molecular Biology. Aug, 2007 | Pubmed ID: 17599356 The Crystal Structure of the Secreted Aspartic Proteinase 3 from Candida Albicans and Its Complex with Pepstatin A Proteins. Aug, 2007 | Pubmed ID: 17510964 Marinobacter Salsuginis Sp. Nov., Isolated from the Brine-seawater Interface of the Shaban Deep, Red Sea International Journal of Systematic and Evolutionary Microbiology. May, 2007 | Pubmed ID: 17473254 A Robust Metallo-oxidase from the Hyperthermophilic Bacterium Aquifex Aeolicus The FEBS Journal. Jun, 2007 | Pubmed ID: 17451433 Crystal Structure of the Catalytic Domain of DESC1, a New Member of the Type II Transmembrane Serine Proteinase Family The FEBS Journal. Apr, 2007 | Pubmed ID: 17388811 Phase-sensitive Optical Coherence Tomography at Up to 370,000 Lines Per Second Using Buffered Fourier Domain Mode-locked Lasers Optics Letters. Mar, 2007 | Pubmed ID: 17308582 Open and Closed Structures of the UDP-glucose Pyrophosphorylase from Leishmania Major The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17303565 Dissociation and Recombination in the Photochemical Decay of Carbonyl Cyanide CO(CN)2 in Cryogenic Matrixes The Journal of Physical Chemistry. A. Feb, 2007 | Pubmed ID: 17266215 Crystal Structure of the Human Carboxypeptidase N (kininase I) Catalytic Domain Journal of Molecular Biology. Feb, 2007 | Pubmed ID: 17157876 Characterization of Two Splice Variants of Human Organic Anion Transporting Polypeptide 3A1 Isolated from Human Brain American Journal of Physiology. Cell Physiology. Feb, 2007 | Pubmed ID: 16971491 Buffered Fourier Domain Mode Locking: Unidirectional Swept Laser Sources for Optical Coherence Tomography Imaging at 370,000 Lines/s Optics Letters. Oct, 2006 | Pubmed ID: 17001371 Crystal Structure of 12-oxophytodienoate Reductase 3 from Tomato: Self-inhibition by Dimerization Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16983071 The Crystal Structure of the Rare-cutting Restriction Enzyme SdaI Reveals Unexpected Domain Architecture Structure (London, England : 1993). Sep, 2006 | Pubmed ID: 16962970 Crystal Structures of Human Tissue Kallikrein 4: Activity Modulation by a Specific Zinc Binding Site Journal of Molecular Biology. Oct, 2006 | Pubmed ID: 16950394 Structural Basis for the Inhibition of Insulin-like Growth Factors by Insulin-like Growth Factor-binding Proteins Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16924115 A Cold-loving Crenarchaeon is a Substantial Part of a Novel Microbial Community in Cold Sulphidic Marsh Water FEMS Microbiology Ecology. Jul, 2006 | Pubmed ID: 16819950 Biosynthesis of Riboflavin: Structure and Properties of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate Reductase of Methanocaldococcus Jannaschii Journal of Molecular Biology. Jun, 2006 | Pubmed ID: 16730025 Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of Beta-lactone Ring Opening and a Mechanism for Irreversible Binding Journal of the American Chemical Society. Apr, 2006 | Pubmed ID: 16608349 First Steps of Retinal Photoisomerization in Proteorhodopsin Biophysical Journal. Jul, 2006 | Pubmed ID: 16603495 Inhibitor-binding Mode of Homobelactosin C to Proteasomes: New Insights into Class I MHC Ligand Generation Proceedings of the National Academy of Sciences of the United States of America. Mar, 2006 | Pubmed ID: 16537370 X-ray Structures of Free and Leupeptin-complexed Human AlphaI-tryptase Mutants: Indication for an Alpha-->beta-tryptase Transition Journal of Molecular Biology. Mar, 2006 | Pubmed ID: 16414069 New Insights into the Lifestyle of the Cold-loving SM1 Euryarchaeon: Natural Growth As a Monospecies Biofilm in the Subsurface Applied and Environmental Microbiology. Jan, 2006 | Pubmed ID: 16391042 Rigidity and Flexibility of Dipeptidyl Peptidase IV: Crystal Structures of and Docking Experiments with DPIV Journal of Molecular Biology. Jan, 2006 | Pubmed ID: 16330047 Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: Stereochemical Implications The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16272154 Peptidyl Prolyl Cis/trans-isomerases: Comparative Reactivities of Cyclophilins, FK506-binding Proteins, and Parvulins with Fluorinated Oligopeptide and Protein Substrates Biochemistry. Dec, 2005 | Pubmed ID: 16331962 Purification, Crystallization, and X-ray Analysis of the Yeast 20S Proteasome Methods in Enzymology. 2005 | Pubmed ID: 16275340 Structure of the Metal-independent Restriction Enzyme BfiI Reveals Fusion of a Specific DNA-binding Domain with a Nonspecific Nuclease Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16247004 Crystal Structures of Active SRC Kinase Domain Complexes Journal of Molecular Biology. Oct, 2005 | Pubmed ID: 16168436 Study of a Major Intermediate in the Oxidative Folding of Leech Carboxypeptidase Inhibitor: Contribution of the Fourth Disulfide Bond Journal of Molecular Biology. Sep, 2005 | Pubmed ID: 16126224 Gene Transfer and Genome Plasticity in Thermotoga Maritima, a Model Hyperthermophilic Species Journal of Bacteriology. Jul, 2005 | Pubmed ID: 15995209 X-ray Snapshots of Peptide Processing in Mutants of Tricorn-interacting Factor F1 from Thermoplasma Acidophilum The Journal of Biological Chemistry. Sep, 2005 | Pubmed ID: 15994304 The Three-dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode Journal of Molecular Biology. Jul, 2005 | Pubmed ID: 15961103 Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma Acidophilum, a Zinc Aminopeptidase in Three Different Conformations Journal of Molecular Biology. Jun, 2005 | Pubmed ID: 15893768 The Endoproteinase Furin Contains Two Essential Ca2+ Ions Stabilizing Its N-terminus and the Unique S1 Specificity Pocket Acta Crystallographica. Section D, Biological Crystallography. May, 2005 | Pubmed ID: 15858259 The Unique Structure of Archaeal 'hami', Highly Complex Cell Appendages with Nano-grappling Hooks Molecular Microbiology. Apr, 2005 | Pubmed ID: 15813730 The 1.1 A Resolution Crystal Structure of the P130cas SH3 Domain and Ramifications for Ligand Selectivity Journal of Molecular Biology. Apr, 2005 | Pubmed ID: 15784259 Structural and Spectral Response of Aequorea Victoria Green Fluorescent Proteins to Chromophore Fluorination Biochemistry. Mar, 2005 | Pubmed ID: 15751943 Structures of Escherichia Coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15699042 PH-dependent Photoisomerization of Retinal in Proteorhodopsin Biochemistry. Feb, 2005 | Pubmed ID: 15697205 Molecular Machines for Protein Degradation Chembiochem : a European Journal of Chemical Biology. Feb, 2005 | Pubmed ID: 15678420 Localization of Organic Anion Transporting Polypeptides in the Rat and Human Ciliary Body Epithelium Experimental Eye Research. Jan, 2005 | Pubmed ID: 15652527 Structural Basis for the Regulation of Insulin-like Growth Factors by IGF Binding Proteins Structure (London, England : 1993). Jan, 2005 | Pubmed ID: 15642270 Design and Crystal Structures of Protein Kinase B-selective Inhibitors in Complex with Protein Kinase A and Mutants Journal of Medicinal Chemistry. Jan, 2005 | Pubmed ID: 15634010 Application of QSAR Analysis to Organic Anion Transporting Polypeptide 1a5 (Oatp1a5) Substrates Bioorganic & Medicinal Chemistry. Jan, 2005 | Pubmed ID: 15598568 Ecology and Microbial Structures of Archaeal/bacterial Strings-of-pearls Communities and Archaeal Relatives Thriving in Cold Sulfidic Springs FEMS Microbiology Ecology. Oct, 2004 | Pubmed ID: 19712372 Photochemistry of Molecules Relevant to the Atmosphere: Photodissociation of Nitric Acid in the Gas Phase Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Nov, 2004 | Pubmed ID: 15580925 Structure of the Streptococcal Endopeptidase IdeS, a Cysteine Proteinase with Strict Specificity for IgG Proceedings of the National Academy of Sciences of the United States of America. Dec, 2004 | Pubmed ID: 15574492 Inhibitors of the Eukaryotic 20S Proteasome Core Particle: a Structural Approach Biochimica Et Biophysica Acta. Nov, 2004 | Pubmed ID: 15571807 Varshavsky's Contributions Science (New York, N.Y.). Nov, 2004 | Pubmed ID: 15550643 Structural Basis of CTP-dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia Coli PPC Synthetase Structure (London, England : 1993). Nov, 2004 | Pubmed ID: 15530362 Evolution of Vitamin B2 Biosynthesis. A Novel Class of Riboflavin Synthase in Archaea Journal of Molecular Biology. Oct, 2004 | Pubmed ID: 15381435 Binding Mode of TMC-95A Analogues to Eukaryotic 20S Proteasome Chembiochem : a European Journal of Chemical Biology. Sep, 2004 | Pubmed ID: 15368577 Structural Basis for the Interaction of Escherichia Coli NusA with Protein N of Phage Lambda Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15365170 Molecular Structure of the Rod Domain of Dictyostelium Filamin Journal of Molecular Biology. Oct, 2004 | Pubmed ID: 15364587 Cloning, Expression, Crystallization and Initial Crystallographic Analysis of the C-terminal Domain of the Amyloid Precursor Protein APP Acta Crystallographica. Section D, Biological Crystallography. Sep, 2004 | Pubmed ID: 15333934 Potential Anti-infective Targets in Pathogenic Yeasts: Structure and Properties of 3,4-dihydroxy-2-butanone 4-phosphate Synthase of Candida Albicans Journal of Molecular Biology. Aug, 2004 | Pubmed ID: 15328619 Gender-selective Patterns of Aggressive Behavior in Drosophila Melanogaster Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15302936 Active Site Geometry and Substrate Recognition of the Molybdenum Hydroxylase Quinoline 2-oxidoreductase Structure (London, England : 1993). Aug, 2004 | Pubmed ID: 15296736 Structural Basis of Charge Transfer Complex Formation by Riboflavin Bound to 6,7-dimethyl-8-ribityllumazine Synthase European Journal of Biochemistry / FEBS. Aug, 2004 | Pubmed ID: 15265040 A Fast Photoswitch for Minimally Perturbed Peptides: Investigation of the Trans-->cis Photoisomerization of N-methylthioacetamide Journal of the American Chemical Society. Jul, 2004 | Pubmed ID: 15250736 1.2 A Crystal Structure of the Serine Carboxyl Proteinase Pro-kumamolisin; Structure of an Intact Pro-subtilase Structure (London, England : 1993). Jul, 2004 | Pubmed ID: 15242607 Ethological Analyses of Crayfish Behavior: a New Invertebrate System for Measuring the Rewarding Properties of Psychostimulants Behavioural Brain Research. Aug, 2004 | Pubmed ID: 15219718 Biochemical Characterization of Bacillus Subtilis Type II Isopentenyl Diphosphate Isomerase, and Phylogenetic Distribution of Isoprenoid Biosynthesis Pathways European Journal of Biochemistry / FEBS. Jul, 2004 | Pubmed ID: 15206931 The Typically Disordered N-terminus of PKA Can Fold As a Helix and Project the Myristoylation Site into Solution Biochemistry. Jun, 2004 | Pubmed ID: 15196017 A Rapid Method for Analyzing Recombinant Protein Inclusion Bodies by Mass Spectrometry Analytical Biochemistry. Jul, 2004 | Pubmed ID: 15183772 Biosynthesis of Tetrahydrofolate in Plants: Crystal Structure of 7,8-dihydroneopterin Aldolase from Arabidopsis Thaliana Reveals a Novel Adolase Class Journal of Molecular Biology. Jun, 2004 | Pubmed ID: 15165863 The Role of Emotional Systems in Addiction: a Neuroethological Perspective Nebraska Symposium on Motivation. Nebraska Symposium on Motivation. 2004 | Pubmed ID: 15160639 Structure of the Molybdenum-cofactor Biosynthesis Protein MoaB of Escherichia Coli Acta Crystallographica. Section D, Biological Crystallography. Jun, 2004 | Pubmed ID: 15159566 Crystallographic Evidence for Isomeric Chromophores in 3-fluorotyrosyl-green Fluorescent Protein Chembiochem : a European Journal of Chemical Biology. May, 2004 | Pubmed ID: 15122645 The Crystal Structures of Zea Mays and Arabidopsis 4-hydroxyphenylpyruvate Dioxygenase Plant Physiology. Apr, 2004 | Pubmed ID: 15084729 The Genome Sequence of the Extreme Thermophile Thermus Thermophilus Nature Biotechnology. May, 2004 | Pubmed ID: 15064768 Crystal Structure of Protoporphyrinogen IX Oxidase: a Key Enzyme in Haem and Chlorophyll Biosynthesis The EMBO Journal. Apr, 2004 | Pubmed ID: 15057273 Phenanthridinium As an Artificial Base and Charge Donor in DNA Angewandte Chemie (International Ed. in English). Mar, 2004 | Pubmed ID: 15054791 The 2.0 A Crystal Structure and Substrate Specificity of the KDEL-tailed Cysteine Endopeptidase Functioning in Programmed Cell Death of Ricinus Communis Endosperm Journal of Molecular Biology. Mar, 2004 | Pubmed ID: 15037072 Structure-based Optimization of Novel Azepane Derivatives As PKB Inhibitors Journal of Medicinal Chemistry. Mar, 2004 | Pubmed ID: 14998327 The Protein Kinase C Inhibitor Bisindolyl Maleimide 2 Binds with Reversed Orientations to Different Conformations of Protein Kinase A The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 14996846 Synthesis of DNA with Phenanthridinium As an Artificial DNA Base The Journal of Organic Chemistry. Feb, 2004 | Pubmed ID: 14750800 A Functional Ni-Ni-[4Fe-4S] Cluster in the Monomeric Acetyl-CoA Synthase from Carboxydothermus Hydrogenoformans Proceedings of the National Academy of Sciences of the United States of America. Jan, 2004 | Pubmed ID: 14699043 Crystal Structure of Fervidolysin from Fervidobacterium Pennivorans, a Keratinolytic Enzyme Related to Subtilisin Journal of Molecular Biology. Jan, 2004 | Pubmed ID: 14687574 Riboflavin Synthase of Schizosaccharomyces Pombe. Protein Dynamics Revealed by 19F NMR Protein Perturbation Experiments BMC Biochemistry. Dec, 2003 | Pubmed ID: 14690539 Aggression in Invertebrates Current Opinion in Neurobiology. Dec, 2003 | Pubmed ID: 14662376 Protein Kinase A in Complex with Rho-kinase Inhibitors Y-27632, Fasudil, and H-1152P: Structural Basis of Selectivity Structure (London, England : 1993). Dec, 2003 | Pubmed ID: 14656443 The Crystal Structure of Murine CMP-5-N-acetylneuraminic Acid Synthetase Journal of Molecular Biology. Dec, 2003 | Pubmed ID: 14636592 Liposomes in Assessment of Annexin-membrane Interactions Methods in Enzymology. 2003 | Pubmed ID: 14610814 Staphylocoagulase is a Prototype for the Mechanism of Cofactor-induced Zymogen Activation Nature. Oct, 2003 | Pubmed ID: 14523451 The Isolation and Characterization of Cytochrome C Nitrite Reductase Subunits (NrfA and NrfH) from Desulfovibrio Desulfuricans ATCC 27774. Re-evaluation of the Spectroscopic Data and Redox Properties European Journal of Biochemistry / FEBS. Oct, 2003 | Pubmed ID: 14511372 Oxygen-dependent Coproporphyrinogen-III Oxidase from Escherichia Coli: One-step Purification and Biochemical Characterisation FEMS Microbiology Letters. Sep, 2003 | Pubmed ID: 13129604 X-ray Structure of Isoaspartyl Dipeptidase from E.coli: a Dinuclear Zinc Peptidase Evolved from Amidohydrolases Journal of Molecular Biology. Sep, 2003 | Pubmed ID: 12946361 Pyrene As a Fluorescent Probe for DNA Base Radicals Chemical Communications (Cambridge, England). Aug, 2003 | Pubmed ID: 12932012 Structure and Properties of an Engineered Transketolase from Maize Plant Physiology. Aug, 2003 | Pubmed ID: 12913150 Structure of 3,4-dihydroxy-2-butanone 4-phosphate Synthase from Methanococcus Jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-phosphate: Implications for the Catalytic Mechanism The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12904291 Structure of MrsD, an FAD-binding Protein of the HFCD Family Acta Crystallographica. Section D, Biological Crystallography. Aug, 2003 | Pubmed ID: 12876343 Structural Insights into the Antigenicity of Myelin Oligodendrocyte Glycoprotein Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003 | Pubmed ID: 12874380 In Situ Growth of the Novel SM1 Euryarchaeon from a String-of-pearls-like Microbial Community in Its Cold Biotope, Its Physical Separation and Insights into Its Structure and Physiology Archives of Microbiology. Sep, 2003 | Pubmed ID: 12856110 Crystal Structure of the Carboxyltransferase Subunit of the Bacterial Sodium Ion Pump Glutaconyl-coenzyme A Decarboxylase The EMBO Journal. Jul, 2003 | Pubmed ID: 12853465 Mutants of Protein Kinase A That Mimic the ATP-binding Site of Protein Kinase B (AKT) Journal of Molecular Biology. Jun, 2003 | Pubmed ID: 12798691 Crystal Structure of the Type II Isopentenyl Diphosphate:dimethylallyl Diphosphate Isomerase from Bacillus Subtilis Journal of Molecular Biology. Jun, 2003 | Pubmed ID: 12798687 The Crystal Structure of the Proprotein Processing Proteinase Furin Explains Its Stringent Specificity Nature Structural Biology. Jul, 2003 | Pubmed ID: 12794637 Hyperthermostabilization of Bacillus Licheniformis Alpha-amylase and Modulation of Its Stability over a 50 Degrees C Temperature Range Protein Engineering. Apr, 2003 | Pubmed ID: 12736372 Expansion of the Genetic Code Enables Design of a Novel "gold" Class of Green Fluorescent Proteins Journal of Molecular Biology. May, 2003 | Pubmed ID: 12729742 Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization Journal of Molecular Biology. May, 2003 | Pubmed ID: 12729736 Determinants of Enzymatic Specificity in the Cys-Met-metabolism PLP-dependent Enzymes Family: Crystal Structure of Cystathionine Gamma-lyase from Yeast and Intrafamiliar Structure Comparison Biological Chemistry. Mar, 2003 | Pubmed ID: 12715888 The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals Its Functional Regulation and Enzymatic Mechanism Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12690074 Substrate Access and Processing by the 20S Proteasome Core Particle The International Journal of Biochemistry & Cell Biology. May, 2003 | Pubmed ID: 12672453 Isolation and Characterization of the Prokaryotic Proteasome Homolog HslVU (ClpQY) from Thermotoga Maritima and the Crystal Structure of HslV Biophysical Chemistry. 2003 | Pubmed ID: 12646382 Isolation, Characterization and Electron Microscopic Single Particle Analysis of the NADH:ubiquinone Oxidoreductase (complex I) from the Hyperthermophilic Eubacterium Aquifex Aeolicus Biochemistry. Mar, 2003 | Pubmed ID: 12627969 Structural Basis of Fosmidomycin Action Revealed by the Complex with 2-C-methyl-D-erythritol 4-phosphate Synthase (IspC). Implications for the Catalytic Mechanism and Anti-malaria Drug Development The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12621040 Cytochrome C Nitrite Reductase from Desulfovibrio Desulfuricans ATCC 27774. The Relevance of the Two Calcium Sites in the Structure of the Catalytic Subunit (NrfA) The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12618432 Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate Journal of Molecular Biology. Mar, 2003 | Pubmed ID: 12614618 Investigations on the Maturation and Regulation of Archaebacterial Proteasomes Journal of Molecular Biology. Mar, 2003 | Pubmed ID: 12614609 Crystal Structure of Schizosaccharomyces Pombe Riboflavin Kinase Reveals a Novel ATP and Riboflavin-binding Fold Journal of Molecular Biology. Mar, 2003 | Pubmed ID: 12595258 The 2008 Lindau Nobel Laureate Meeting: Robert Huber, Chemistry 1988 Robert Huber JoVE 1128 Editorial
The 2008 Lindau Nobel Laureate Meeting: Robert Huber, Chemistry 1988 Robert Huber JoVE 1128 Editorial