Roland Baur

Publications

• Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors
  The Journal of Biological Chemistry. Aug, 2016  |   Pubmed ID: 27382064
• Molecular Mode of Action of CGS 9895 at α1 β2 γ2 GABAA Receptors
  Journal of Neurochemistry. Sep, 2016  |   Pubmed ID: 27319298
• Novel Positive Allosteric Modulators of GABAA Receptors with Anesthetic Activity
  Scientific Reports. May, 2016  |   Pubmed ID: 27198062
• A New Chromanone Derivative Isolated from Hypericum Lissophloeus (Hypericaceae) Potentiates GABAA Receptor Currents in a Subunit Specific Fashion
  Bioorganic & Medicinal Chemistry. Feb, 2016  |   Pubmed ID: 26791864
• Functional Sites Involved in Modulation of the GABAA Receptor Channel by the Intravenous Anesthetics Propofol, Etomidate and Pentobarbital
  Neuropharmacology. Jun, 2016  |   Pubmed ID: 26767954
• Modulatory Effects of Eschscholzia Californica Alkaloids on Recombinant GABAA Receptors
  Biochemistry Research International. 2015  |   Pubmed ID: 26509084
• Positive Modulation of Synaptic and Extrasynaptic GABAA Receptors by an Antagonist of the High Affinity Benzodiazepine Binding Site
  Neuropharmacology. Aug, 2015  |   Pubmed ID: 25963418
• Monepantel Irreversibly Binds to and Opens Haemonchus Contortus MPTL-1 and Caenorhabditis Elegans ACR-20 Receptors
  Molecular Pharmacology. Jan, 2015  |   Pubmed ID: 25352042
• Structural Analogues of the Natural Products Magnolol and Honokiol As Potent Allosteric Potentiators of GABA(A) Receptors
  Bioorganic & Medicinal Chemistry. Dec, 2014  |   Pubmed ID: 25456080
• A Pentasymmetric Open Channel Blocker for Cys-loop Receptor Channels
  PloS One. 2014  |   Pubmed ID: 25184303
• Moderate Concentrations of 4-O-methylhonokiol Potentiate GABAA Receptor Currents Stronger Than Honokiol
  Biochimica Et Biophysica Acta. Oct, 2014  |   Pubmed ID: 24973566
• Accelerated Discovery of Novel Benzodiazepine Ligands by Experiment-guided Virtual Screening
  ACS Chemical Biology. Aug, 2014  |   Pubmed ID: 24960548
• Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl Glycerol (2-AG) Share Mode of Action and the Binding Site on the β2 Subunit of GABAA Receptors?
  PeerJ. 2013  |   Pubmed ID: 24058880
• Dementia: Treating Patients and Caregivers with Complementary and Alternative Medicine--results of a Clinical Expert Conference Using the World Café Method
  Forschende Komplementarmedizin (2006). 2013  |   Pubmed ID: 24030449
• Acr-23 Encodes a Monepantel-sensitive Channel in Caenorhabditis Elegans
  PLoS Pathogens. 2013  |   Pubmed ID: 23950710
• Effects and Feasibility of an Integrative Medicine Program for Geriatric Patients-a Cluster-randomized Pilot Study
  Clinical Interventions in Aging. 2013  |   Pubmed ID: 23901266
• Molecular Analysis of the Site for 2-arachidonylglycerol (2-AG) on the β₂ Subunit of GABA(A) Receptors
  Journal of Neurochemistry. Jul, 2013  |   Pubmed ID: 23600744
• Influence of GABA(A) Receptor α Subunit Isoforms on the Benzodiazepine Binding Site
  PloS One. 2012  |   Pubmed ID: 22848717
• The Major Central Endocannabinoid Directly Acts at GABA(A) Receptors
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011  |   Pubmed ID: 22025726
• A Residue Close to α1 Loop F Disrupts Modulation of GABAA Receptors by Benzodiazepines While Their Binding is Maintained
  Journal of Neurochemistry. Dec, 2010  |   Pubmed ID: 20946417
• Monepantel Allosterically Activates DEG-3/DES-2 Channels of the Gastrointestinal Nematode Haemonchus Contortus
  Molecular Pharmacology. Nov, 2010  |   Pubmed ID: 20679419
• Diversity of Structure and Function of Alpha1alpha6beta3delta GABAA Receptors: Comparison with Alpha1beta3delta and Alpha6beta3delta Receptors
  The Journal of Biological Chemistry. Jun, 2010  |   Pubmed ID: 20382738
• Highly Potent Modulation of GABA(A) Receptors by Valerenic Acid Derivatives
  ChemMedChem. May, 2010  |   Pubmed ID: 20235267
• Use of Concatamers to Study GABAA Receptor Architecture and Function: Application to Delta-subunit-containing Receptors and Possible Pitfalls
  Biochemical Society Transactions. Dec, 2009  |   Pubmed ID: 19909272
• Relative Positioning of Diazepam in the Benzodiazepine-binding-pocket of GABA Receptors
  Journal of Neurochemistry. Dec, 2009  |   Pubmed ID: 19804380
• Structure of Alpha6 Beta3 Delta GABA(A) Receptors and Their Lack of Ethanol Sensitivity
  Journal of Neurochemistry. Dec, 2009  |   Pubmed ID: 19765192
• Homeopathic Treatment of Patients with Chronic Low Back Pain: A Prospective Observational Study with 2 Years' Follow-up
  The Clinical Journal of Pain. May, 2009  |   Pubmed ID: 19590483
• Unanticipated Structural and Functional Properties of Delta-subunit-containing GABAA Receptors
  The Journal of Biological Chemistry. Mar, 2009  |   Pubmed ID: 19141615
• Covalent Modification of GABAA Receptor Isoforms by a Diazepam Analogue Provides Evidence for a Novel Benzodiazepine Binding Site That Prevents Modulation by These Drugs
  Journal of Neurochemistry. Sep, 2008  |   Pubmed ID: 18643789
• Novel Chloride Channel Mutations Leading to Mild Myotonia Among Chinese
  Neuromuscular Disorders : NMD. Aug, 2008  |   Pubmed ID: 18579381
• The Promiscuous Role of the Epsilon Subunit in GABAA Receptor Biogenesis
  Molecular and Cellular Neurosciences. Mar, 2008  |   Pubmed ID: 18206389
• Replacement of Histidine in Position 105 in the α₅ Subunit by Cysteine Stimulates Zolpidem Sensitivity of α₅β₂γ₂ GABA(A) Receptors
  Journal of Neurochemistry. Dec, 2007  |   Pubmed ID: 17953656
• Two Neighboring Residues of Loop A of the Alpha1 Subunit Point Towards the Benzodiazepine Binding Site of GABAA Receptors
  FEBS Letters. Oct, 2007  |   Pubmed ID: 17854801
• Proximity-accelerated Chemical Coupling Reaction in the Benzodiazepine-binding Site of Gamma-aminobutyric Acid Type A Receptors: Superposition of Different Allosteric Modulators
  The Journal of Biological Chemistry. Sep, 2007  |   Pubmed ID: 17626010
• A GABA(A) Receptor of Defined Subunit Composition and Positioning: Concatenation of Five Subunits
  FEBS Letters. Mar, 2006  |   Pubmed ID: 16494876
• Consequence of the Presence of Two Different Beta Subunit Isoforms in a GABA(A) Receptor
  Journal of Neurochemistry. Dec, 2005  |   Pubmed ID: 16300645
• Influence of the Point Mutation Alpha-1-H101R on the Assembly of Gamma-aminobutyric Acid Type A Receptors
  Neuroreport. Nov, 2005  |   Pubmed ID: 16272886
• Homeopathic Medical Practice: Long-term Results of a Cohort Study with 3981 Patients
  BMC Public Health. Nov, 2005  |   Pubmed ID: 16266440
• Novel Plant Substances Acting As Beta Subunit Isoform-selective Positive Allosteric Modulators of GABAA Receptors
  Molecular Pharmacology. Sep, 2005  |   Pubmed ID: 15939801
• Conformational Changes at Benzodiazepine Binding Sites of GABA(A) Receptors Detected with a Novel Technique
  Journal of Neurochemistry. Feb, 2005  |   Pubmed ID: 15686488
• Benzodiazepines Affect Channel Opening of GABA A Receptors Induced by Either Agonist Binding Site
  Molecular Pharmacology. Apr, 2005  |   Pubmed ID: 15657366
• The Flavone Hispidulin, a Benzodiazepine Receptor Ligand with Positive Allosteric Properties, Traverses the Blood-brain Barrier and Exhibits Anticonvulsive Effects
  British Journal of Pharmacology. Jul, 2004  |   Pubmed ID: 15231642
• Individual Properties of the Two Functional Agonist Sites in GABA(A) Receptors
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2003  |   Pubmed ID: 14657175
• Naturally Occurring 2'-hydroxyl-substituted Flavonoids As High-affinity Benzodiazepine Site Ligands
  Biochemical Pharmacology. Dec, 2003  |   Pubmed ID: 14637197
• On High- and Low-affinity Agonist Sites in GABAA Receptors
  Journal of Neurochemistry. Oct, 2003  |   Pubmed ID: 14511110
• Anxiolytic Effect of Wogonin, a Benzodiazepine Receptor Ligand Isolated from Scutellaria Baicalensis Georgi
  Biochemical Pharmacology. Nov, 2002  |   Pubmed ID: 12392823
• Forced Subunit Assembly in Alpha1beta2gamma2 GABAA Receptors. Insight into the Absolute Arrangement
  The Journal of Biological Chemistry. Nov, 2002  |   Pubmed ID: 12324466
• Functional Characterization of the New Human GABA(A) Receptor Mutation Beta3(R192H)
  Human Genetics. Aug, 2002  |   Pubmed ID: 12189488
• N-Substituted 4-amino-3,3-dipropyl-2(3H)-furanones: New Positive Allosteric Modulators of the GABA(A) Receptor Sharing Electrophysiological Properties with the Anticonvulsant Loreclezole
  Journal of Medicinal Chemistry. Jun, 2002  |   Pubmed ID: 12061884