Roland Malli

Publications

• Intact Mitochondrial Ca(2+) Uniport is Essential for Agonist-induced Activation of Endothelial Nitric Oxide Synthase (eNOS)
  Free Radical Biology & Medicine. Jan, 2017  |   Pubmed ID: 27923677
• Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin
  The Journal of Biological Chemistry. Nov, 2016  |   Pubmed ID: 27679490
• PRMT1-mediated Methylation of MICU1 Determines the UCP2/3 Dependency of Mitochondrial Ca(2+) Uptake in Immortalized Cells
  Nature Communications. Sep, 2016  |   Pubmed ID: 27642082
• Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2016  |   Pubmed ID: 27606689
• Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo
  Cell Chemical Biology. Jun, 2016  |   Pubmed ID: 27341431
• Development of Novel FP-based Probes for Live-cell Imaging of Nitric Oxide Dynamics
  Nature Communications. Feb, 2016  |   Pubmed ID: 26842907
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition)
  Autophagy. Jan, 2016  |   Pubmed ID: 26799652
• Rearrangement of MICU1 Multimers for Activation of MCU is Solely Controlled by Cytosolic Ca(2.)
  Scientific Reports. Oct, 2015  |   Pubmed ID: 26489515
• UCP2 Modulates Single-channel Properties of a MCU-dependent Ca(2+) Inward Current in Mitochondria
  Pflugers Archiv : European Journal of Physiology. Dec, 2015  |   Pubmed ID: 26275882
• Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum
  Sensors (Basel, Switzerland). Jun, 2015  |   Pubmed ID: 26053751
• Assessment of Mitochondrial Ca²⁺ Uptake
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25631032
• Oleoyl-lysophosphatidylcholine Limits Endothelial Nitric Oxide Bioavailability by Induction of Reactive Oxygen Species
  PloS One. 2014  |   Pubmed ID: 25419657
• TRPV1 Mediates Cellular Uptake of Anandamide and Thus Promotes Endothelial Cell Proliferation and Network-formation
  Biology Open. Nov, 2014  |   Pubmed ID: 25395667
• Characterization of Rat Serum Amyloid A4 (SAA4): a Novel Member of the SAA Superfamily
  Biochemical and Biophysical Research Communications. Aug, 2014  |   Pubmed ID: 25044109
• IP3-mediated STIM1 Oligomerization Requires Intact Mitochondrial Ca2+ Uptake
  Journal of Cell Science. Jul, 2014  |   Pubmed ID: 24806964
• Adaptations of Energy Metabolism Associated with Increased Levels of Mitochondrial Cholesterol in Niemann-Pick Type C1-deficient Cells
  The Journal of Biological Chemistry. Jun, 2014  |   Pubmed ID: 24790103
• ATP Increases Within the Lumen of the Endoplasmic Reticulum Upon Intracellular Ca2+ Release
  Molecular Biology of the Cell. Feb, 2014  |   Pubmed ID: 24307679
• Mitochondrial Ca(2+) Uniporter (MCU)-dependent and MCU-independent Ca(2+) Channels Coexist in the Inner Mitochondrial Membrane
  Pflugers Archiv : European Journal of Physiology. Jul, 2014  |   Pubmed ID: 24162235
• Molecularly Distinct Routes of Mitochondrial Ca2+ Uptake Are Activated Depending on the Activity of the Sarco/endoplasmic Reticulum Ca2+ ATPase (SERCA)
  The Journal of Biological Chemistry. May, 2013  |   Pubmed ID: 23592775
• N-Arachidonoyl Glycine Suppresses Na⁺/Ca²⁺ Exchanger-mediated Ca²⁺ Entry into Endothelial Cells and Activates BK(Ca) Channels Independently of GPCRs
  British Journal of Pharmacology. Jun, 2013  |   Pubmed ID: 23517055
• Characterization of Distinct Single-channel Properties of Ca²⁺ Inward Currents in Mitochondria
  Pflugers Archiv : European Journal of Physiology. Jul, 2013  |   Pubmed ID: 23397170
• The Endocannabinoid N-arachidonoyl Glycine (NAGly) Inhibits Store-operated Ca2+ Entry by Preventing STIM1-Orai1 Interaction
  Journal of Cell Science. Feb, 2013  |   Pubmed ID: 23239024
• 小説レッド シフト ミトコンドリアのターゲットを絞った Cameleon を用いたゾル性細胞質とミトコンドリアのカルシウム信号の時空間相関。
  PloS One. 2012  |   Pubmed ID: 23029314
• Mitochondrial Ca2+ Uptake 1 (MICU1) and Mitochondrial Ca2+ Uniporter (MCU) Contribute to Metabolism-secretion Coupling in Clonal Pancreatic β-cells
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22904319
• Acyl Chain-dependent Effect of Lysophosphatidylcholine on Cyclooxygenase (COX)-2 Expression in Endothelial Cells
  Atherosclerosis. Oct, 2012  |   Pubmed ID: 22901457
• The Vascular Barrier-protecting Hawthorn Extract WS® 1442 Raises Endothelial Calcium Levels by Inhibition of SERCA and Activation of the IP3 Pathway
  Journal of Molecular and Cellular Cardiology. Oct, 2012  |   Pubmed ID: 22814436
• パルミチン酸誘起ネクロトーシス内皮細胞のオートファジーの阻害を救助します。
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22556413
• Mutation in NSUN2, Which Encodes an RNA Methyltransferase, Causes Autosomal-recessive Intellectual Disability
  American Journal of Human Genetics. May, 2012  |   Pubmed ID: 22541562
• Docosahexaenoic Acid-induced Unfolded Protein Response, Cell Cycle Arrest, and Apoptosis in Vascular Smooth Muscle Cells Are Triggered by Ca²⁺-dependent Induction of Oxidative Stress
  Free Radical Biology & Medicine. May, 2012  |   Pubmed ID: 22391221
• Endothelial Mitochondria--less Respiration, More Integration
  Pflugers Archiv : European Journal of Physiology. Jul, 2012  |   Pubmed ID: 22382745
• Studying Mitochondrial Ca(2+) Uptake - a Revisit
  Molecular and Cellular Endocrinology. Apr, 2012  |   Pubmed ID: 22100614
• Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways
  The Journal of Biological Chemistry. Aug, 2011  |   Pubmed ID: 21613221
• The GPR55 Agonist Lysophosphatidylinositol Directly Activates Intermediate-conductance Ca2+ -activated K+ Channels
  Pflugers Archiv : European Journal of Physiology. Aug, 2011  |   Pubmed ID: 21603896
• Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture and in Vivo
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21454708
• Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
  The Journal of Biological Chemistry. Mar, 2011  |   Pubmed ID: 21196579
• Uncoupling Protein 3 Adjusts Mitochondrial Ca(2+) Uptake to High and Low Ca(2+) Signals
  Cell Calcium. Nov, 2010  |   Pubmed ID: 21047682
• GPR55-dependent and -independent Ion Signalling in Response to Lysophosphatidylinositol in Endothelial Cells
  British Journal of Pharmacology. Sep, 2010  |   Pubmed ID: 20735417
• Acyl Chain-dependent Effect of Lysophosphatidylcholine on Endothelial Prostacyclin Production
  Journal of Lipid Research. Oct, 2010  |   Pubmed ID: 20610733
• Mitochondrial Ca2+ Uptake and Not Mitochondrial Motility is Required for STIM1-Orai1-dependent Store-operated Ca2+ Entry
  Journal of Cell Science. Aug, 2010  |   Pubmed ID: 20587595
• The Contribution of UCP2 and UCP3 to Mitochondrial Ca(2+) Uptake is Differentially Determined by the Source of Supplied Ca(2+)
  Cell Calcium. May, 2010  |   Pubmed ID: 20403634
• Vesicular Calcium Regulates Coat Retention, Fusogenicity, and Size of Pre-Golgi Intermediates
  Molecular Biology of the Cell. Mar, 2010  |   Pubmed ID: 20089833
• Mitochondrial Ca2+ Channels: Great Unknowns with Important Functions
  FEBS Letters. May, 2010  |   Pubmed ID: 20074570
• Lysophosphatidic Acid Receptor Activation Affects the C13NJ Microglia Cell Line Proteome Leading to Alterations in Glycolysis, Motility, and Cytoskeletal Architecture
  Proteomics. Jan, 2010  |   Pubmed ID: 19899077
• Mitochondrial Protein Phosphorylation: Instigator or Target of Lipotoxicity?
  Trends in Endocrinology and Metabolism: TEM. May, 2009  |   Pubmed ID: 19356948
• Cytosolic Ca2+ Prevents the Subplasmalemmal Clustering of STIM1: an Intrinsic Mechanism to Avoid Ca2+ Overload
  Journal of Cell Science. Oct, 2008  |   Pubmed ID: 18765567
• Integrin Clustering Enables Anandamide-induced Ca2+ Signaling in Endothelial Cells Via GPR55 by Protection Against CB1-receptor-triggered Repression
  Journal of Cell Science. May, 2008  |   Pubmed ID: 18445684
• The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding
  The Journal of Biological Chemistry. Jun, 2008  |   Pubmed ID: 18445597
• Mitochondrial Ca2+, the Secret Behind the Function of Uncoupling Proteins 2 and 3?
  Cell Calcium. Jul, 2008  |   Pubmed ID: 18282596
• Mitochondria and Ca(2+) Signaling: Old Guests, New Functions
  Pflugers Archiv : European Journal of Physiology. Dec, 2007  |   Pubmed ID: 17611770
• Uncoupling Proteins 2 and 3 Are Fundamental for Mitochondrial Ca2+ Uniport
  Nature Cell Biology. Apr, 2007  |   Pubmed ID: 17351641
• Mg2+ Deprivation Elicits Rapid Ca2+ Uptake and Activates Ca2+/calcineurin Signaling in Saccharomyces Cerevisiae
  Eukaryotic Cell. Apr, 2007  |   Pubmed ID: 17337637
• Mitochondria Maintain Maturation and Secretion of Lipoprotein Lipase in the Endoplasmic Reticulum
  The Biochemical Journal. May, 2006  |   Pubmed ID: 16466345
• A New Type of Non-Ca2+-buffering Apo(a)-based Fluorescent Indicator for Intraluminal Ca2+ in the Endoplasmic Reticulum
  The Journal of Biological Chemistry. Feb, 2006  |   Pubmed ID: 16368693
• Twenty Years of Calcium Imaging: Cell Physiology to Dye For
  Molecular Interventions. Apr, 2005  |   Pubmed ID: 15821159
• Hyperglycemic Conditions Affect Shape and Ca2+ Homeostasis of Mitochondria in Endothelial Cells
  Journal of Cardiovascular Pharmacology. Oct, 2004  |   Pubmed ID: 15454850
• Kisspeptin 10 キス 1/metastin 由来の Decapeptide プライマリひと培養トロホブ ラストの生理的侵略阻害剤です。
  Journal of Cell Science. Mar, 2004  |   Pubmed ID: 15020672
• Heterozygous Missense Mutations in BSCL2 Are Associated with Distal Hereditary Motor Neuropathy and Silver Syndrome
  Nature Genetics. Mar, 2004  |   Pubmed ID: 14981520
• Anandamide Initiates Ca(2+) Signaling Via CB2 Receptor Linked to Phospholipase C in Calf Pulmonary Endothelial Cells
  British Journal of Pharmacology. Dec, 2003  |   Pubmed ID: 14645143
• Sustained Ca2+ Transfer Across Mitochondria is Essential for Mitochondrial Ca2+ Buffering, Sore-operated Ca2+ Entry, and Ca2+ Store Refilling
  The Journal of Biological Chemistry. Nov, 2003  |   Pubmed ID: 12941956
• Mitochondria Efficiently Buffer Subplasmalemmal Ca2+ Elevation During Agonist Stimulation
  The Journal of Biological Chemistry. Mar, 2003  |   Pubmed ID: 12529366
• Novel High Energy Intermediate Analogues with Triazasterol-related Structures As Inhibitors of Ergosterol Biosynthesis. Part I: Synthesis and Antifungal Activity of N-alkyl-N'-(phenethyl- and Cyclohexenylethyl)guanidines and N2-substituted 2-imidazolinamines
  Archiv Der Pharmazie. 2002  |   Pubmed ID: 12596218
• Nitric Oxide Inhibits Capacitative Ca2+ Entry by Suppression of Mitochondrial Ca2+ Handling
  British Journal of Pharmacology. Nov, 2002  |   Pubmed ID: 12411413
• Functional Analysis of Histamine Receptor Subtypes Involved in Endothelium-mediated Relaxation of the Human Uterine Artery
  Clinical and Experimental Pharmacology & Physiology. Aug, 2002  |   Pubmed ID: 12100006
• Subplasmalemmal Endoplasmic Reticulum Controls K(Ca) Channel Activity Upon Stimulation with a Moderate Histamine Concentration in a Human Umbilical Vein Endothelial Cell Line
  The Journal of Physiology. Apr, 2002  |   Pubmed ID: 11927670
• Tissue-specific Expression of Human Lipoprotein Lipase in the Vascular System Affects Vascular Reactivity in Transgenic Mice
  British Journal of Pharmacology. Jan, 2002  |   Pubmed ID: 11786490
• Oxidized Phospholipids Stimulate Tissue Factor Expression in Human Endothelial Cells Via Activation of ERK/EGR-1 and Ca(++)/NFAT
  Blood. Jan, 2002  |   Pubmed ID: 11756172