Articles by Rosario Merino-García in JoVE
Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate Rosario Merino-García1, Samuel Hernández-Anzaldo1, Yasmi Reyes-Ortega1 1Centro de Química, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla Herein, we report the synthesis and crystallization of 3,5-lutidine N-oxide dehydrate by a simple protocol that differs from the classical synthesis of pyridine N-oxide. This protocol utilizes different starting material and involves less reaction time to yield a new solvated supramolecular structure, which crystallizes under slow evaporation.
Other articles by Rosario Merino-García on PubMed
Crystal Structure of 3,5-di-methyl-pyridine -oxide Dihydrate Acta Crystallographica. Section E, Crystallographic Communications. Dec, 2016 | Pubmed ID: 27980810 In the title compound, also known as 3,5-lutidine -oxide dihydrate, CHNO·2HO, the N-O bond is weakened due to the involvement of the O atom as an acceptor of hydrogen bonds from the two water mol-ecules of crystallization present in the asymmetric unit. Fused (10) ring motifs based on O-H⋯O hydrogen bonds form chains in the  direction, which are further connected by weak C-H⋯O inter-molecular contacts. As a result, the lutidine mol-ecules are stacked in an efficient manner, with π-π contacts characterized by a short separation of 3.569 (1) Å between the benzene rings.