Salvador Ventura Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular Universitat Autònoma de Barcelona Biography Publications Institution JoVE Articles Salvador Ventura has not added a biography. If you are Salvador Ventura and would like to personalize this page please email our Author Liaison for assistance. Publications Minimalist Prion-Inspired Polar Self-Assembling Peptides ACS Nano. Jun, 2018 | Pubmed ID: 29812908 The Disordered C-Terminus of Yeast Hsf1 Contains a Cryptic Low-Complexity Amyloidogenic Region International Journal of Molecular Sciences. May, 2018 | Pubmed ID: 29734798 AGGRESCAN3D: Toward the Prediction of the Aggregation Propensities of Protein Structures Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29594784 Molecular and Clinical Aspects of Protein Aggregation Assays in Neurodegenerative Diseases Molecular Neurobiology. Feb, 2018 | Pubmed ID: 29429052 A Single Cysteine Post-translational Oxidation Suffices to Compromise Globular Proteins Kinetic Stability and Promote Amyloid Formation Redox Biology. Apr, 2018 | Pubmed ID: 29132128 Disulfide Driven Folding for a Conditionally Disordered Protein Scientific Reports. Dec, 2017 | Pubmed ID: 29208936 Characterization of Soft Amyloid Cores in Human Prion-Like Proteins Scientific Reports. Sep, 2017 | Pubmed ID: 28935930 Plasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI) Scientific Reports. Jul, 2017 | Pubmed ID: 28710462 Advances in the Prediction of Protein Aggregation Propensity Current Medicinal Chemistry. Jul, 2017 | Pubmed ID: 28685682 Perfecting Prediction of Mutational Impact on the Aggregation Propensity of the ALS-associated HnRNPA2 Prion-like Protein FEBS Letters. 07, 2017 | Pubmed ID: 28542905 Protein Aggregation into Insoluble Deposits Protects from Oxidative Stress Redox Biology. 08, 2017 | Pubmed ID: 28410533 The Transcription Terminator Rho: A First Bacterial Prion Trends in Microbiology. 06, 2017 | Pubmed ID: 28392113 Cavity Filling Mutations at the Thyroxine-binding Site Dramatically Increase Transthyretin Stability and Prevent Its Aggregation Scientific Reports. Mar, 2017 | Pubmed ID: 28338000 Copper(II) and the Pathological H50Q α-synuclein Mutant: Environment Meets Genetics Communicative & Integrative Biology. 2017 | Pubmed ID: 28289488 Amyloid Cores in Prion Domains: Key Regulators for Prion Conformational Conversion Prion. Jan, 2017 | Pubmed ID: 28281928 Prion-like Proteins and Their Computational Identification in Proteomes Expert Review of Proteomics. 04, 2017 | Pubmed ID: 28271922 High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors International Journal of Molecular Sciences. Mar, 2017 | Pubmed ID: 28257086 DisProt 7.0: a Major Update of the Database of Disordered Proteins Nucleic Acids Research. Jan, 2017 | Pubmed ID: 27965415 DisProt 7.0: a Major Update of the Database of Disordered Proteins Nucleic Acids Research. Jan, 2017 | Pubmed ID: 27899601 The Effects of the Novel A53E Alpha-synuclein Mutation on Its Oligomerization and Aggregation Acta Neuropathologica Communications. 12, 2016 | Pubmed ID: 27938414 Dissecting the Contribution of Staphylococcus Aureus α-phenol-soluble Modulins to Biofilm Amyloid Structure Scientific Reports. 10, 2016 | Pubmed ID: 27708403 Environmental and Genetic Factors Support the Dissociation Between α-synuclein Aggregation and Toxicity Proceedings of the National Academy of Sciences of the United States of America. 10, 2016 | Pubmed ID: 27708160 Characterization of Amyloid Cores in Prion Domains Scientific Reports. Sep, 2016 | Pubmed ID: 27686217 Editorial: Protein Solubility and Aggregation in Bacteria Frontiers in Microbiology. 2016 | Pubmed ID: 27524982 Understanding and Predicting Protein Misfolding and Aggregation: Insights from Proteomics Proteomics. 10, 2016 | Pubmed ID: 27479752 Data on Correlation Between Aβ42 Structural Aggregation Propensity and Toxicity in Bacteria Data in Brief. Jun, 2016 | Pubmed ID: 27408907 Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals PLoS Pathogens. Jun, 2016 | Pubmed ID: 27327765 Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation International Journal of Molecular Sciences. Jun, 2016 | Pubmed ID: 27322259 Mammalian Prion Amyloid Formation in Bacteria Prion. 03, 2016 | Pubmed ID: 26910379 Repositioning Tolcapone As a Potent Inhibitor of Transthyretin Amyloidogenesis and Associated Cellular Toxicity Nature Communications. Feb, 2016 | Pubmed ID: 26902880 Amyloid Properties of the Leader Peptide of Variant B Cystatin C: Implications for Alzheimer and Macular Degeneration FEBS Letters. Mar, 2016 | Pubmed ID: 26865059 Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis PLoS Genetics. Jan, 2016 | Pubmed ID: 26815787 Curing Bacterial Infections with Protein Aggregates Molecular Microbiology. Mar, 2016 | Pubmed ID: 26714186 A Fast and Specific Method to Screen for Intracellular Amyloid Inhibitors Using Bacterial Model Systems European Journal of Medicinal Chemistry. Oct, 2016 | Pubmed ID: 26608003 In Vivo Amyloid Aggregation Kinetics Tracked by Time-lapse Confocal Microscopy in Real-time Biotechnology Journal. Jan, 2016 | Pubmed ID: 26580000 Possible Roles of Amyloids in Malaria Pathophysiology Future Science OA. Sep, 2015 | Pubmed ID: 28031872 Aggregation Propensity of Neuronal Receptors: Potential Implications in Neurodegenerative Disorders Future Science OA. Sep, 2015 | Pubmed ID: 28031868 Protein Misfolding Diseases Future Science OA. Sep, 2015 | Pubmed ID: 28031867 The Rho Termination Factor of Clostridium Botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core Frontiers in Microbiology. 2015 | Pubmed ID: 26779170 Mammalian Prion Protein (PrP) Forms Conformationally Different Amyloid Intracellular Aggregates in Bacteria Microbial Cell Factories. Nov, 2015 | Pubmed ID: 26536866 Computational Analysis of Candidate Prion-like Proteins in Bacteria and Their Role Frontiers in Microbiology. 2015 | Pubmed ID: 26528269 Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor PloS One. 2015 | Pubmed ID: 26168158 The Prion-like RNA-processing Protein HNRPDL Forms Inherently Toxic Amyloid-like Inclusion Bodies in Bacteria Microbial Cell Factories. Jul, 2015 | Pubmed ID: 26160665 PrionW: a Server to Identify Proteins Containing Glutamine/asparagine Rich Prion-like Domains and Their Amyloid Cores Nucleic Acids Research. Jul, 2015 | Pubmed ID: 25977297 AGGRESCAN3D (A3D): Server for Prediction of Aggregation Properties of Protein Structures Nucleic Acids Research. Jul, 2015 | Pubmed ID: 25883144 Proteome Response at the Edge of Protein Aggregation Open Biology. Feb, 2015 | Pubmed ID: 25673330 What Makes a Protein Sequence a Prion? PLoS Computational Biology. Jan, 2015 | Pubmed ID: 25569335 Characterization of Amyloid-like Properties in Bacterial Intracellular Aggregates Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25447861 Amyloid Formation by Human Carboxypeptidase D Transthyretin-like Domain Under Physiological Conditions The Journal of Biological Chemistry. Dec, 2014 | Pubmed ID: 25294878 Fluorescent Dye ProteoStat to Detect and Discriminate Intracellular Amyloid-like Aggregates in Escherichia Coli Biotechnology Journal. Oct, 2014 | Pubmed ID: 25112199 The Small GTPase Rab11 Co-localizes with α-synuclein in Intracellular Inclusions and Modulates Its Aggregation, Secretion and Toxicity Human Molecular Genetics. Dec, 2014 | Pubmed ID: 25092884 The Importance of a Gatekeeper Residue on the Aggregation of Transthyretin: Implications for Transthyretin-related Amyloidoses The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25086037 Association Between Foldability and Aggregation Propensity in Small Disulfide-rich Proteins Antioxidants & Redox Signaling. Jul, 2014 | Pubmed ID: 24635049 The Mitochondrial Intermembrane Space Oxireductase Mia40 Funnels the Oxidative Folding Pathway of the Cytochrome C Oxidase Assembly Protein Cox19 The Journal of Biological Chemistry. Apr, 2014 | Pubmed ID: 24569988 N-terminal Protein Tails Act As Aggregation Protective Entropic Bristles: the SUMO Case Biomacromolecules. Apr, 2014 | Pubmed ID: 24564702 Screening for Amyloid Aggregation: In-silico, In-vitro and In-vivo Detection Current Protein & Peptide Science. 2014 | Pubmed ID: 24555899 PrionScan: an Online Database of Predicted Prion Domains in Complete Proteomes BMC Genomics. Feb, 2014 | Pubmed ID: 24498877 Selection Against Toxic Aggregation-prone Protein Sequences in Bacteria Biochimica Et Biophysica Acta. May, 2014 | Pubmed ID: 24472658 Structure-based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy PloS One. 2013 | Pubmed ID: 24358189 Protein Aggregation Propensity is a Crucial Determinant of Intracellular Inclusion Formation and Quality Control Degradation Biochimica Et Biophysica Acta. Dec, 2013 | Pubmed ID: 23856334 Discovering Putative Prion Sequences in Complete Proteomes Using Probabilistic Representations of Q/N-rich Domains BMC Genomics. May, 2013 | Pubmed ID: 23663289 The N-terminal Helix Controls the Transition Between the Soluble and Amyloid States of an FF Domain PloS One. 2013 | Pubmed ID: 23505482 About Targets and Causes in Protein Folding Journal of Biomolecular Structure & Dynamics. 2013 | Pubmed ID: 23297814 Zinc Induced Folding is Essential for TIM15 Activity As an MtHsp70 Chaperone Biochimica Et Biophysica Acta. Jan, 2013 | Pubmed ID: 23063975 Cross-β-sheet Supersecondary Structure in Amyloid Folds: Techniques for Detection and Characterization Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 22987357 Modeling Amyloids in Bacteria Microbial Cell Factories. Dec, 2012 | Pubmed ID: 23272903 Protein Aggregation Profile of the Human Kinome Frontiers in Physiology. 2012 | Pubmed ID: 23181023 Thioflavin-S Staining Coupled to Flow Cytometry. A Screening Tool to Detect in Vivo Protein Aggregation Molecular BioSystems. Nov, 2012 | Pubmed ID: 22868714 Yeast Prions Form Infectious Amyloid Inclusion Bodies in Bacteria Microbial Cell Factories. Jun, 2012 | Pubmed ID: 22731490 Protein Oxidative Folding in the Intermembrane Mitochondrial Space: More Than Protein Trafficking Current Protein & Peptide Science. May, 2012 | Pubmed ID: 22612783 Native Structure Protects SUMO Proteins from Aggregation into Amyloid Fibrils Biomacromolecules. Jun, 2012 | Pubmed ID: 22559198 Using Bacterial Inclusion Bodies to Screen for Amyloid Aggregation Inhibitors Microbial Cell Factories. May, 2012 | Pubmed ID: 22553999 Effect of the Surface Charge of Artificial Model Membranes on the Aggregation of Amyloid β-peptide Biochimie. Aug, 2012 | Pubmed ID: 22542639 The Effect of Amyloidogenic Peptides on Bacterial Aging Correlates with Their Intrinsic Aggregation Propensity Journal of Molecular Biology. Aug, 2012 | Pubmed ID: 22200483 AGGRESCAN: Method, Application, and Perspectives for Drug Design Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22183539 Temperature Dependence of the Aggregation Kinetics of Sup35 and Ure2p Yeast Prions Biomacromolecules. Feb, 2012 | Pubmed ID: 22176525 Contribution of Disulfide Bonds to Stability, Folding, and Amyloid Fibril Formation: the PI3-SH3 Domain Case Antioxidants & Redox Signaling. Jan, 2012 | Pubmed ID: 21797671 Biological Role of Bacterial Inclusion Bodies: a Model for Amyloid Aggregation The FEBS Journal. Jul, 2011 | Pubmed ID: 21569209 The Aggregation Properties of Escherichia Coli Proteins Associated with Their Cellular Abundance Biotechnology Journal. Jun, 2011 | Pubmed ID: 21538899 Linking Amyloid Protein Aggregation and Yeast Survival Molecular BioSystems. Apr, 2011 | Pubmed ID: 21240401 Does Stoichiometry Drive Protein Folding? Journal of Biomolecular Structure & Dynamics. Feb, 2011 | Pubmed ID: 21142251 Protease Inhibitors As Models for the Study of Oxidative Folding Antioxidants & Redox Signaling. Jan, 2011 | Pubmed ID: 20812859 Deciphering the Role of the Thermodynamic and Kinetic Stabilities of SH3 Domains on Their Aggregation Inside Bacteria Proteomics. Dec, 2010 | Pubmed ID: 21086517 Amyloid-like Protein Inclusions in Tobacco Transgenic Plants PloS One. Oct, 2010 | Pubmed ID: 21049018 The Role of Protein Sequence and Amino Acid Composition in Amyloid Formation: Scrambling and Backward Reading of IAPP Amyloid Fibrils Journal of Molecular Biology. Nov, 2010 | Pubmed ID: 20887731 Protein Folding and Aggregation in Bacteria Cellular and Molecular Life Sciences : CMLS. Aug, 2010 | Pubmed ID: 20358253 Protein Aggregation Profile of the Bacterial Cytosol PloS One. Feb, 2010 | Pubmed ID: 20195530 Characterization of the Amyloid Bacterial Inclusion Bodies of the HET-s Fungal Prion Microbial Cell Factories. Oct, 2009 | Pubmed ID: 19863787 Deciphering the Structural Basis That Guides the Oxidative Folding of Leech-derived Tryptase Inhibitor The Journal of Biological Chemistry. Dec, 2009 | Pubmed ID: 19820233 Amyloidogenic Regions and Interaction Surfaces Overlap in Globular Proteins Related to Conformational Diseases PLoS Computational Biology. Aug, 2009 | Pubmed ID: 19696882 Amyloids in Bacterial Inclusion Bodies Trends in Biochemical Sciences. Aug, 2009 | Pubmed ID: 19647433 Designing out Disulfide Bonds of Leech Carboxypeptidase Inhibitor: Implications for Its Folding, Stability and Function Journal of Molecular Biology. Sep, 2009 | Pubmed ID: 19559710 Protein Complementation Assays: Approaches for the in Vivo Analysis of Protein Interactions FEBS Letters. Jun, 2009 | Pubmed ID: 19269288 Detecting and Interfering Protein Interactions: Towards the Control of Biochemical Pathways Current Medicinal Chemistry. 2009 | Pubmed ID: 19149583 Design, Selection, and Characterization of Thioflavin-based Intercalation Compounds with Metal Chelating Properties for Application in Alzheimer's Disease Journal of the American Chemical Society. Feb, 2009 | Pubmed ID: 19133767 Kinetic and Thermodynamic Stability of Bacterial Intracellular Aggregates FEBS Letters. Oct, 2008 | Pubmed ID: 18840434 Monitoring the Interference of Protein-protein Interactions in Vivo by Bimolecular Fluorescence Complementation: the DnaK Case Proteomics. Sep, 2008 | Pubmed ID: 18686297 Studies on Bacterial Inclusion Bodies Future Microbiology. Aug, 2008 | Pubmed ID: 18651814 The NMR Structures of the Major Intermediates of the Two-domain Tick Carboxypeptidase Inhibitor Reveal Symmetry in Its Folding and Unfolding Pathways The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18640980 Inclusion Bodies: Specificity in Their Aggregation Process and Amyloid-like Structure Biochimica Et Biophysica Acta. Oct, 2008 | Pubmed ID: 18619498 Direct Interaction Between a Human Digestive Protease and the Mucoadhesive Poly(acrylic Acid) Acta Crystallographica. Section D, Biological Crystallography. Jul, 2008 | Pubmed ID: 18566513 The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate with Their Conformational Stability: the SH3 Case Journal of Molecular Biology. May, 2008 | Pubmed ID: 18423663 Study and Selection of in Vivo Protein Interactions by Coupling Bimolecular Fluorescence Complementation and Flow Cytometry Nature Protocols. 2008 | Pubmed ID: 18193018 Oxidative Folding of Leech-derived Tryptase Inhibitor Via Native Disulfide-bonded Intermediates Antioxidants & Redox Signaling. Jan, 2008 | Pubmed ID: 18004973 Self-assembly of Human Latexin into Amyloid-like Oligomers BMC Structural Biology. Nov, 2007 | Pubmed ID: 17996039 Detection of Transient Protein-protein Interactions by Bimolecular Fluorescence Complementation: the Abl-SH3 Case Proteomics. Apr, 2007 | Pubmed ID: 17352427 AGGRESCAN: a Server for the Prediction and Evaluation of "hot Spots" of Aggregation in Polypeptides BMC Bioinformatics. Feb, 2007 | Pubmed ID: 17324296 Ile-phe Dipeptide Self-assembly: Clues to Amyloid Formation Biophysical Journal. Mar, 2007 | Pubmed ID: 17172307 Effect of Temperature on Protein Quality in Bacterial Inclusion Bodies FEBS Letters. Nov, 2006 | Pubmed ID: 17101131 Design and NMR Conformational Study of a Beta-sheet Peptide Based on Betanova and WW Domains Protein Science : a Publication of the Protein Society. Oct, 2006 | Pubmed ID: 16963647 The Chaperone DnaK Controls the Fractioning of Functional Protein Between Soluble and Insoluble Cell Fractions in Inclusion Body-forming Cells Microbial Cell Factories. Aug, 2006 | Pubmed ID: 16893469 Characterizing the Tick Carboxypeptidase Inhibitor: Molecular Basis for Its Two-domain Nature The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16760476 Protein Activity in Bacterial Inclusion Bodies Correlates with Predicted Aggregation Rates Journal of Biotechnology. Aug, 2006 | Pubmed ID: 16621081 Folding of Small Disulfide-rich Proteins: Clarifying the Puzzle Trends in Biochemical Sciences. May, 2006 | Pubmed ID: 16600598 Protein Quality in Bacterial Inclusion Bodies Trends in Biotechnology. Apr, 2006 | Pubmed ID: 16503059 Mutagenesis of the Central Hydrophobic Cluster in Abeta42 Alzheimer's Peptide. Side-chain Properties Correlate with Aggregation Propensities The FEBS Journal. Feb, 2006 | Pubmed ID: 16420488 Prediction of "hot Spots" of Aggregation in Disease-linked Polypeptides BMC Structural Biology. Sep, 2005 | Pubmed ID: 16197548 Aggregation As Bacterial Inclusion Bodies Does Not Imply Inactivation of Enzymes and Fluorescent Proteins Microbial Cell Factories. Sep, 2005 | Pubmed ID: 16156893 Study of a Major Intermediate in the Oxidative Folding of Leech Carboxypeptidase Inhibitor: Contribution of the Fourth Disulfide Bond Journal of Molecular Biology. Sep, 2005 | Pubmed ID: 16126224 NMR Structural Characterization and Computational Predictions of the Major Intermediate in Oxidative Folding of Leech Carboxypeptidase Inhibitor Structure (London, England : 1993). Aug, 2005 | Pubmed ID: 16084391 Sequence Determinants of Protein Aggregation: Tools to Increase Protein Solubility Microbial Cell Factories. Apr, 2005 | Pubmed ID: 15847694 Amyloid-like Properties of Bacterial Inclusion Bodies Journal of Molecular Biology. Apr, 2005 | Pubmed ID: 15784261 Structure of Human Carboxypeptidase A4 with Its Endogenous Protein Inhibitor, Latexin Proceedings of the National Academy of Sciences of the United States of America. Mar, 2005 | Pubmed ID: 15738388 Amyloid Fibril Formation by a Partially Structured Intermediate State of Alpha-chymotrypsin Journal of Molecular Biology. Sep, 2004 | Pubmed ID: 15313627 Human Kallikrein 6 Activity is Regulated Via an Autoproteolytic Mechanism of Activation/inactivation Biological Chemistry. Jun, 2004 | Pubmed ID: 15255184 Role of Kinetic Intermediates in the Folding of Leech Carboxypeptidase Inhibitor The Journal of Biological Chemistry. Sep, 2004 | Pubmed ID: 15226306 Secondary Binding Site of the Potato Carboxypeptidase Inhibitor. Contribution to Its Structure, Folding, and Biological Properties Biochemistry. Jun, 2004 | Pubmed ID: 15196042 Designing Proteins from the Inside Out Proteins. Jul, 2004 | Pubmed ID: 15162481 Short Amino Acid Stretches Can Mediate Amyloid Formation in Globular Proteins: the Src Homology 3 (SH3) Case Proceedings of the National Academy of Sciences of the United States of America. May, 2004 | Pubmed ID: 15123800 تقييم أثر تراكم البروتين في الأكسدة الخلوية في الخميرة Anita Carija1, Salvador Ventura1, Susanna Navarro1 1Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona JoVE 57470 Biochemistry
تقييم أثر تراكم البروتين في الأكسدة الخلوية في الخميرة Anita Carija1, Salvador Ventura1, Susanna Navarro1 1Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona JoVE 57470 Biochemistry